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Linearized PDF PDFMetadata: Objects: 690 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Association of serum and fecal microRNA profiles in cats with gastrointestinal cancer and chronic inflammatory enteropathy Destination: atl_JVIM_16813_ Children: Item: Title: 1 INTRODUCTION Destination: HeadingJVIM_16813jvim16813-sec-0007 Item: Title: 2 MATERIALS AND METHODS Destination: HeadingJVIM_16813jvim16813-sec-0008 Children: Item: Title: 2.1 Study design and ethics approval Destination: HeadingJVIM_16813jvim16813-sec-0009 Item: Title: 2.2 Cat recruitment Destination: HeadingJVIM_16813jvim16813-sec-0010 Item: Title: 2.3 Sample collection Destination: HeadingJVIM_16813jvim16813-sec-0011 Item: Title: 2.4 RNA isolation Destination: HeadingJVIM_16813jvim16813-sec-0012 Item: Title: 2.5 Small RNAseq screening Destination: HeadingJVIM_16813jvim16813-sec-0013 Item: Title: 2.6 RT-qPCR identification of miRNA biomarker candidates Destination: HeadingJVIM_16813jvim16813-sec-0014 Item: Title: 2.7 Data analyses Destination: HeadingJVIM_16813jvim16813-sec-0015 Children: Item: Title: 2.7.1 Clinical data Destination: HeadingJVIM_16813jvim16813-sec-0016 Item: Title: 2.7.2 Small RNAseq data Destination: HeadingJVIM_16813jvim16813-sec-0017 Item: Title: 2.7.3 qPCR data Destination: HeadingJVIM_16813jvim16813-sec-0018 Item: Title: 3 RESULTS Destination: HeadingJVIM_16813jvim16813-sec-0019 Children: Item: Title: 3.1 Cat characteristics Destination: HeadingJVIM_16813jvim16813-sec-0020 Item: Title: 3.2 RNA isolation Destination: HeadingJVIM_16813jvim16813-sec-0021 Item: Title: 3.3 Small RNAseq screening of cat serum and feces Destination: HeadingJVIM_16813jvim16813-sec-0022 Children: Item: Title: 3.3.1 Serum Destination: HeadingJVIM_16813jvim16813-sec-0023 Item: Title: 3.3.2 Feces Destination: HeadingJVIM_16813jvim16813-sec-0024 Item: Title: 3.4 qPCR identification of cat miRNA biomarkers that differentiate GIC from CIE Destination: HeadingJVIM_16813jvim16813-sec-0025 Children: Item: Title: 3.4.1 Serum Destination: HeadingJVIM_16813jvim16813-sec-0026 Item: Title: 3.4.2 Feces Destination: HeadingJVIM_16813jvim16813-sec-0027 Item: Title: 3.5 Diagnostic performance of serum miR-223-3p for differentiation of GIC from CIE or healthy cats Destination: HeadingJVIM_16813jvim16813-sec-0028 Item: Title: 3.6 qPCR identification of cat miRNA biomarkers that differentiate SCL from CIE Destination: HeadingJVIM_16813jvim16813-sec-0029 Children: Item: Title: 3.6.1 Serum Destination: HeadingJVIM_16813jvim16813-sec-0030 Item: Title: 3.6.2 Feces Destination: HeadingJVIM_16813jvim16813-sec-0031 Item: Title: 4 DISCUSSION Destination: HeadingJVIM_16813jvim16813-sec-0032 Item: Title: ACKNOWLEDGMENT Destination: HeadingJVIM_16813jvim16813-sec-0033 Item: Title: CONFLICT OF INTEREST STATEMENT Destination: HeadingJVIM_16813jvim16813-sec-0034 Children: Item: Title: DATA AVAILABILITY STATEMENT Destination: 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