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Title:           Unveiling the role of PUS7-mediated pseudouridylation in host protein interactions specific for the SARS-CoV-2 RNA genome
Subject:         Molecular Therapy: Nucleic Acid, 34 (2023) 102052. doi:10.1016/j.omtn.2023.102052
Author:          Roberto Giambruno
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      Title: Unveiling the role of PUS7-mediated pseudouridylation in host protein interactions specific for the SARS-CoV-2 RNA genome
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        Title: Introduction
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        Title: Results
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         Item: 
          Title: Prediction of SARS-CoV-2 regions with the greatest propensity to interact with host proteins
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         Item: 
          Title: Identification of the human interactome for the 5′ and 3′ ends of the SARS-CoV-2 genome
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         Item: 
          Title: Correlation between computationally predicted and experimentally validated RNA-host protein interactors
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         Item: 
          Title: SARS-CoV-2 sgRNAs bear multiple putative pseudouridylated sites
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         Item: 
          Title: PUS7-dependent pseudouridylation of TRS-L could modulate the binding of NSP1 to the viral 5′ UTR
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        Title: Discussion
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        Title: Materials and methods
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          Title: Preliminary predictions of protein-RNA interactions
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          Title: Reagents and plasmids
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          Title: Cell lines
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          Title: Virus isolation and cell infection
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          Title: RNA extraction and nanopore DRS
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          Title: RaPID assay
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          Title: In-gel digestion
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          Title: Nano-LC-MS/MS analysis
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          Title: Data analysis of MS data
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          Title: Computational evaluation of experimental interactions
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          Title: GO analysis
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          Title: RNA secondary structure investigation
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          Title: Nanopore DRS and nanocompore analysis
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          Title: Merging analysis
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          Title: Comparison with RaPID fragments
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          Title: Genomic RNAs analysis
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          Title: UV-RIP assay
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        Title: Data and code availability
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        Title: Declaration of interests
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   Type: CRC32
  Checksum: a9a87823068ebda06b0de2fe642facf2
   Type: MD5
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