01fef2f93ad9d963e339b33a27cb7fbd  pmc_10632909.pdf
d640db4cf42eee6faeb293853a5801e03c4f17f3  pmc_10632909.pdf
cc3cb8af1253b202864f4e1de47ed0078732c3dd823fd0a90effca27de8a20b7  pmc_10632909.pdf

Creator:         Adobe InDesign CS6 (Windows)
Producer:        Adobe PDF Library 10.0.1
CreationDate:    Tue Nov  7 07:23:25 2023 CET
ModDate:         Tue Nov  7 07:23:27 2023 CET
Custom Metadata: yes
Metadata Stream: yes
Tagged:          no
UserProperties:  no
Suspects:        no
Form:            none
JavaScript:      no
Pages:           10
Encrypted:       no
Page size:       595.276 x 793.701 pts
Page rot:        0
File size:       4422755 bytes
Optimized:       yes
PDF version:     1.4


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
WPGUEW+HelveticaNeueLTStd-Bd         Type 1C           Custom           yes yes yes    222  0
PTNXPK+HelveticaNeueLTStd-BdCn       Type 1C           WinAnsi          yes yes yes    230  0
WNFPEW+HelveticaLTStd-BoldCond       Type 1C           WinAnsi          yes yes yes    231  0
SVBUFE+HelveticaNeueLTStd-Cn         Type 1C           Custom           yes yes yes    232  0
QSCIDI+HelveticaNeueLTStd-CnO        Type 1C           Custom           yes yes yes    233  0
DIPFYI+HelveticaNeueLTStd-Roman      Type 1C           Custom           yes yes yes    234  0
AGBIIO+Helvetica-Condensed-Bold      Type 1C           WinAnsi          yes yes yes    250  0
ZCRCUQ+NewBaskerville-Roman          Type 1C           Custom           yes yes yes    252  0
TTPSOC+Symbol                        Type 1C           Custom           yes yes yes    253  0
OBETWM+BookAntiqua-Bold              TrueType          WinAnsi          yes yes yes    238  0
SVBUFE+HelveticaNeueLTStd-Cn         Type 1C           WinAnsi          yes yes yes    293  0
QSCIDI+HelveticaNeueLTStd-CnO        Type 1C           Custom           yes yes yes    295  0
PTNXPK+HelveticaNeueLTStd-BdCn       Type 1C           WinAnsi          yes yes yes    297  0
RQQGMG+SymbolMT                      CID TrueType      Identity-H       yes yes yes    148  0
OJCOWM+NewBaskerville-Bold           Type 1C           WinAnsi          yes yes yes    144  0
LHOWGS+TimesNewRomanPSMT             CID TrueType      Identity-H       yes yes yes    156  0
HWQYCA+Arial-BoldMT                  CID TrueType      Identity-H       yes yes yes    166  0
UFCYCA+FrutigerLTStd-Bold            Type 1C           WinAnsi          yes yes yes    168  0
FGPMAE+HelveticaNeueLTStd-It         Type 1C           Custom           yes yes yes    167  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2025-02-17 17:01:51 CET
 RepresentationInformation: pmc_10632909.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2025-01-28 02:34:40 CET
  Size: 4422755
  Format: PDF
  Version: 1.4
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: Linearized PDF
  PDFMetadata: 
   Objects: 310
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    ViewerPreferences: 
     HideToolbar: false
     HideMenubar: false
     HideWindowUI: false
     FitWindow: false
     CenterWindow: false
     DisplayDocTitle: false
     NonFullScreenPageMode: UseNone
     Direction: L2R
     ViewArea: CropBox
     ViewClip: CropBox
     PrintArea: CropBox
     PageClip: CropBox
    PageLayout: SinglePage
    PageMode: UseNone
    Outlines: 
     Item: 
      Title: Vall d’Hebron Risk Score II for myocardial infarction and cardiac death
      Children: 
       Item: 
        Title: ABSTRACT
       Item: 
        Title: Introduction
       Item: 
        Title: Materials and methods
        Children: 
         Item: 
          Title: Patients
         Item: 
          Title: Exercise stress test
         Item: 
          Title: Myocardial perfusion-gated SPECT
         Item: 
          Title: Clinical outcomes
         Item: 
          Title: Statistical analysis
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: Predictors of CEs in patients without previous myocardial infarction and/or coronary revascularisation
         Item: 
          Title: Predictors of CEs in patients with previous myocardial infarction and/or coronary revascularisation
         Item: 
          Title: Validation group
       Item: 
        Title: Discussion
        Children: 
         Item: 
          Title: Limitations
       Item: 
        Title: Conclusions
       Item: 
        Title: References
   Info: 
    Creator: Adobe InDesign CS6 (Windows)
    Producer: Adobe PDF Library 10.0.1
    CreationDate: Tue Nov 07 07:53:25 CET 2023
    ModDate: Tue Nov 07 07:53:27 CET 2023
   ID: 0xcef289f27ab2d84487ca8d2011ac1506, 0x14fd17b14470184aa645ff070af38af0
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 383
      ImageHeight: 84
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1761
      ImageHeight: 1070
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1704
      ImageHeight: 840
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1684
      ImageHeight: 821
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1752
      ImageHeight: 2533
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
   Fonts: 
    Type0: 
     Font: 
      BaseFont: RQQGMG+SymbolMT
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: HWQYCA+Arial-BoldMT
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: LHOWGS+TimesNewRomanPSMT
      Encoding: Identity-H
      ToUnicode: true
    Type1: 
     Font: 
      BaseFont: OJCOWM+NewBaskerville-Bold
      FontSubset: true
      FirstChar: 55
      LastChar: 55
      FontDescriptor: 
       FontName: OJCOWM+NewBaskerville-Bold
       Flags: Serif, Nonsymbolic
       FontBBox: -196, -270, 1189, 908
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: PTNXPK+HelveticaNeueLTStd-BdCn
      FontSubset: true
      FirstChar: 32
      LastChar: 121
      FontDescriptor: 
       FontName: PTNXPK+HelveticaNeueLTStd-BdCn
       Flags: Nonsymbolic
       FontBBox: -164, -224, 1066, 961
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: WNFPEW+HelveticaLTStd-BoldCond
      FontSubset: true
      FirstChar: 32
      LastChar: 116
      FontDescriptor: 
       FontName: WNFPEW+HelveticaLTStd-BoldCond
       Flags: Nonsymbolic
       FontBBox: -169, -250, 1091, 991
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: FGPMAE+HelveticaNeueLTStd-It
      FontSubset: true
      FirstChar: 31
      LastChar: 118
      FontDescriptor: 
       FontName: FGPMAE+HelveticaNeueLTStd-It
       Flags: Nonsymbolic, Italic
       FontBBox: -166, -214, 1106, 957
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: SVBUFE+HelveticaNeueLTStd-Cn
      FontSubset: true
      FirstChar: 28
      LastChar: 250
      FontDescriptor: 
       FontName: SVBUFE+HelveticaNeueLTStd-Cn
       Flags: Nonsymbolic
       FontBBox: -164, -212, 1000, 932
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: UFCYCA+FrutigerLTStd-Bold
      FontSubset: true
      FirstChar: 67
      LastChar: 83
      FontDescriptor: 
       FontName: UFCYCA+FrutigerLTStd-Bold
       Flags: Nonsymbolic
       FontBBox: -166, -250, 1000, 935
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: QSCIDI+HelveticaNeueLTStd-CnO
      FontSubset: true
      FirstChar: 31
      LastChar: 116
      FontDescriptor: 
       FontName: QSCIDI+HelveticaNeueLTStd-CnO
       Flags: Nonsymbolic, Italic
       FontBBox: -171, -272, 1068, 932
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: AGBIIO+Helvetica-Condensed-Bold
      FontSubset: true
      FirstChar: 65
      LastChar: 84
      FontDescriptor: 
       FontName: AGBIIO+Helvetica-Condensed-Bold
       Flags: Nonsymbolic
       FontBBox: -169, -250, 1091, 991
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: DIPFYI+HelveticaNeueLTStd-Roman
      FontSubset: true
      FirstChar: 29
      LastChar: 243
      FontDescriptor: 
       FontName: DIPFYI+HelveticaNeueLTStd-Roman
       Flags: Nonsymbolic
       FontBBox: -166, -214, 1076, 952
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: ZCRCUQ+NewBaskerville-Roman
      FontSubset: true
      FirstChar: 31
      LastChar: 177
      FontDescriptor: 
       FontName: ZCRCUQ+NewBaskerville-Roman
       Flags: Serif, Nonsymbolic
       FontBBox: -205, -272, 1207, 906
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: TTPSOC+Symbol
      FontSubset: true
      FirstChar: 29
      LastChar: 31
      FontDescriptor: 
       FontName: TTPSOC+Symbol
       Flags: Symbolic
       FontBBox: -180, -293, 1090, 1010
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: WPGUEW+HelveticaNeueLTStd-Bd
      FontSubset: true
      FirstChar: 31
      LastChar: 134
      FontDescriptor: 
       FontName: WPGUEW+HelveticaNeueLTStd-Bd
       Flags: Nonsymbolic
       FontBBox: -166, -218, 1078, 975
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
    TrueType: 
     Font: 
      BaseFont: OBETWM+BookAntiqua-Bold
      FontSubset: true
      FirstChar: 32
      LastChar: 146
      FontDescriptor: 
       FontName: OBETWM+BookAntiqua-Bold
       Flags: Serif, Nonsymbolic
       FontBBox: -134, -337, 1193, 1021
       FontFile2: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
    CIDFontType2: 
     Font: 
      BaseFont: RQQGMG+SymbolMT
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: RQQGMG+SymbolMT
       Flags: Symbolic
       FontBBox: 0, -220, 1113, 1005
       FontFile2: true
     Font: 
      BaseFont: HWQYCA+Arial-BoldMT
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: HWQYCA+Arial-BoldMT
       Flags: Symbolic
       FontBBox: -628, -376, 2000, 1018
       FontFile2: true
     Font: 
      BaseFont: LHOWGS+TimesNewRomanPSMT
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: LHOWGS+TimesNewRomanPSMT
       Flags: Serif, Symbolic
       FontBBox: -568, -307, 2046, 1040
       FontFile2: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 5.3-c011 66.145661, 2012/02/06-14:56:27        ">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:identifier>doi:openhrt-2023-002431</dc:identifier>
         <dc:format>application/pdf</dc:format>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmp="http://ns.adobe.com/xap/1.0/">
         <xmp:CreateDate>2023-11-07T11:53:25+05:30</xmp:CreateDate>
         <xmp:MetadataDate>2023-11-07T11:53:27+05:30</xmp:MetadataDate>
         <xmp:ModifyDate>2023-11-07T11:53:27+05:30</xmp:ModifyDate>
         <xmp:CreatorTool>Adobe InDesign CS6 (Windows)</xmp:CreatorTool>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/"
            xmlns:stRef="http://ns.adobe.com/xap/1.0/sType/ResourceRef#"
            xmlns:stEvt="http://ns.adobe.com/xap/1.0/sType/ResourceEvent#">
         <xmpMM:InstanceID>uuid:dfb0c6e5-64b5-4dca-9a1e-51590e4e317b</xmpMM:InstanceID>
         <xmpMM:OriginalDocumentID>xmp.did:B2C59A163194E611BD009A7CB80B8EC7</xmpMM:OriginalDocumentID>
         <xmpMM:DocumentID>xmp.id:6E2A661F367DEE118743CE31F7C1220B</xmpMM:DocumentID>
         <xmpMM:RenditionClass>proof:pdf</xmpMM:RenditionClass>
         <xmpMM:DerivedFrom rdf:parseType="Resource">
            <stRef:instanceID>xmp.iid:6D2A661F367DEE118743CE31F7C1220B</stRef:instanceID>
            <stRef:documentID>xmp.did:383B9E463D2068118C14CF26067AF65C</stRef:documentID>
            <stRef:originalDocumentID>xmp.did:B2C59A163194E611BD009A7CB80B8EC7</stRef:originalDocumentID>
            <stRef:renditionClass>default</stRef:renditionClass>
         </xmpMM:DerivedFrom>
         <xmpMM:History>
            <rdf:Seq>
               <rdf:li rdf:parseType="Resource">
                  <stEvt:action>converted</stEvt:action>
                  <stEvt:parameters>from application/x-indesign to application/pdf</stEvt:parameters>
                  <stEvt:softwareAgent>Adobe InDesign CS6 (Windows)</stEvt:softwareAgent>
                  <stEvt:changed>/</stEvt:changed>
                  <stEvt:when>2023-11-07T11:53:25+05:30</stEvt:when>
               </rdf:li>
            </rdf:Seq>
         </xmpMM:History>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/">
         <pdfx:jobID>e22f77bc-1470-4abf-9c66-f4b53e1b3b8d</pdfx:jobID>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:Producer>Adobe PDF Library 10.0.1</pdf:Producer>
         <pdf:Trapped>False</pdf:Trapped>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 499, 35, 538, 16
      Annotation: 
       Subtype: Link
       Rect: 39, 34, 64, 18
      Annotation: 
       Subtype: Link
       Rect: 276, 670, 285, 658
      Annotation: 
       Subtype: Link
       Rect: 39, 463, 135, 441
      Annotation: 
       Subtype: Link
       Rect: 173, 218, 186, 206
       ActionDest: 80
      Annotation: 
       Subtype: Link
       Rect: 246, 194, 263, 182
       ActionDest: 80
      Annotation: 
       Subtype: Link
       Rect: 311, 182, 320, 170
       ActionDest: 80
      Annotation: 
       Subtype: Link
       Rect: 291, 110, 298, 98
       ActionDest: 80
      Annotation: 
       Subtype: Link
       Rect: 497, 290, 500, 278
       ActionDest: 80
    Page: 
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 136, 344, 170, 332
       ActionDest: 1
      Annotation: 
       Subtype: Link
       Rect: 178, 332, 181, 320
       ActionDest: 80
      Annotation: 
       Subtype: Link
       Rect: 402, 349, 417, 338
       ActionDest: 80
    Page: 
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 234, 470, 268, 458
       ActionDest: 29
      Annotation: 
       Subtype: Link
       Rect: 41, 458, 76, 446
       ActionDest: 29
      Annotation: 
       Subtype: Link
       Rect: 497, 290, 532, 278
       ActionDest: 33
      Annotation: 
       Subtype: Link
       Rect: 318, 254, 353, 242
       ActionDest: 33
      Annotation: 
       Subtype: Link
       Rect: 420, 230, 458, 218
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 384, 206, 423, 194
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 317, 158, 355, 146
       ActionDest: 59
    Page: 
     Sequence: 4
    Page: 
     Sequence: 5
    Page: 
     Sequence: 6
    Page: 
     Sequence: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 127, 437, 163, 424
       ActionDest: 33
      Annotation: 
       Subtype: Link
       Rect: 224, 412, 260, 400
       ActionDest: 33
      Annotation: 
       Subtype: Link
       Rect: 90, 376, 131, 364
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 64, 352, 105, 340
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 357, 484, 397, 472
       ActionDest: 59
    Page: 
     Sequence: 8
    Page: 
     Sequence: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 131, 662, 173, 650
       ActionDest: 59
      Annotation: 
       Subtype: Link
       Rect: 67, 638, 107, 626
       ActionDest: 59
      Annotation: 
       Subtype: Link
       Rect: 79, 326, 104, 314
       ActionDest: 80
      Annotation: 
       Subtype: Link
       Rect: 349, 482, 355, 470
       ActionDest: 80
      Annotation: 
       Subtype: Link
       Rect: 447, 350, 454, 338
       ActionDest: 80
      Annotation: 
       Subtype: Link
       Rect: 500, 242, 534, 230
       ActionDest: 59
      Annotation: 
       Subtype: Link
       Rect: 365, 182, 398, 170
       ActionDest: 59
    Page: 
     Sequence: 10
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 380, 726, 521, 717
      Annotation: 
       Subtype: Link
       Rect: 382, 699, 499, 690
      Annotation: 
       Subtype: Link
       Rect: 494, 644, 538, 635
      Annotation: 
       Subtype: Link
       Rect: 499, 618, 549, 609
      Annotation: 
       Subtype: Link
       Rect: 322, 610, 348, 601
      Annotation: 
       Subtype: Link
       Rect: 365, 593, 402, 584
      Annotation: 
       Subtype: Link
       Rect: 398, 576, 414, 567
      Annotation: 
       Subtype: Link
       Rect: 352, 550, 397, 541
      Annotation: 
       Subtype: Link
       Rect: 542, 533, 552, 524
      Annotation: 
       Subtype: Link
       Rect: 322, 525, 362, 516
      Annotation: 
       Subtype: Link
       Rect: 449, 491, 528, 482
      Annotation: 
       Subtype: Link
       Rect: 322, 482, 349, 473
      Annotation: 
       Subtype: Link
       Rect: 384, 465, 442, 456
      Annotation: 
       Subtype: Link
       Rect: 388, 440, 426, 431
      Annotation: 
       Subtype: Link
       Rect: 378, 406, 393, 397
      Annotation: 
       Subtype: Link
       Rect: 485, 389, 522, 380
      Annotation: 
       Subtype: Link
       Rect: 322, 329, 360, 320
      Annotation: 
       Subtype: Link
       Rect: 486, 312, 532, 303
      Annotation: 
       Subtype: Link
       Rect: 498, 270, 541, 261
      Annotation: 
       Subtype: Link
       Rect: 441, 244, 476, 235
      Annotation: 
       Subtype: Link
       Rect: 458, 227, 506, 218
      Annotation: 
       Subtype: Link
       Rect: 322, 185, 404, 176
      Annotation: 
       Subtype: Link
       Rect: 507, 168, 531, 159
      Annotation: 
       Subtype: Link
       Rect: 322, 159, 346, 150
      Annotation: 
       Subtype: Link
       Rect: 389, 134, 436, 125
      Annotation: 
       Subtype: Link
       Rect: 410, 108, 468, 99
      Annotation: 
       Subtype: Link
       Rect: 465, 83, 513, 74
  Checksum: c057d9fd
   Type: CRC32
  Checksum: 01fef2f93ad9d963e339b33a27cb7fbd
   Type: MD5
  Checksum: d640db4cf42eee6faeb293853a5801e03c4f17f3
   Type: SHA-1
  Checksum: cc3cb8af1253b202864f4e1de47ed0078732c3dd823fd0a90effca27de8a20b7
   Type: SHA-256