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kinetics of type I IFN genes during acute and chronic LCMV infections Destination: B1 Item: Title: CD169+ marginal zone macrophages produce the second wave of IFN-I expression during acute LCMV infection Destination: B2 Item: Title: Early CD169+ marginal zone macrophage depletion in chronic infection is mediated by CD8+ T’cells Destination: B3 Item: Title: The second wave of type I IFN in acute infected mice is required to induce inflammatory monocytes/macrophages and virus-specific CD8 T’cells Destination: B4 Item: Title: Early IFN-I kinetics determines the appearance of fibrosis in lymphatic’tissue Destination: B5 Item: Title: Discussion Destination: A3 Item: Title: Methods Destination: A4 Children: Item: Title: Mice Destination: B6 Item: Title: Virus infections Destination: B7 Item: Title: In vivo treatments with antibodies Destination: B8 Item: Title: In vivo cell depletion Destination: B9 Item: Title: Flow cytometry and sorting Destination: B10 Item: Title: Magnetic-activated cell sorting Destination: B11 Item: Title: Histological staining Destination: B12 Item: Title: Immunofluorescence Destination: B13 Item: Title: Virus load quantification Destination: B14 Item: Title: ELISA Destination: B15 Item: Title: Quantitative real-time’PCR Destination: B16 Item: Title: RNA-seq library preparation, sequencing and bioinformatic analysis Destination: B17 Item: Title: Quantification and statistical analysis Destination: B18 Item: Title: Reporting summary Destination: B19 Item: Title: References Destination: A5 Item: Title: Acknowledgements Destination: A6 Item: Title: Author contributions Destination: A7 Item: Title: Competing interests Destination: A8 Item: Title: Ethics approval Destination: A9 Item: Title: ACKNOWLEDGMENTS Destination: M1 Item: Title: ADDITIONAL INFORMATION Destination: M1 Info: Title: Differential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation Author: Valentina Casella Subject: Cell Death and 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