e7da749858b13642025834345d96c9ad pmc_10966234.pdf f98e8b224f8e9c233b98e7694d1d08e74a51c8ee pmc_10966234.pdf 528fcc917efeb8b10d6161414d79ecc9b8be4c2f4904c1052713833d66480a03 pmc_10966234.pdf Title: Role of vericiguat in management of patients with heart failure with reduced ejection fraction after worsening episode Subject: Keywords: 10.1002/ehf2.14647 and Heart failure; Sacubitril–valsartan; SGLT2; Vericiguat; Worsening Author: Aleix Olivella, Luis Almenar‐Bonet, Pedro Moliner, Emmanuel Coloma, Antoni Martínez‐Rubio, Marco Paz Bermejo, Ramon Boixeda, German Cediel, Ana Belén Méndez Fernández, Lorenzo Facila Rubio Creator: Arbortext Advanced Print Publisher 9.1.520/W Unicode Producer: Acrobat Distiller 23.0 (Windows) CreationDate: Wed Mar 20 11:44:19 2024 CET ModDate: Mon Mar 25 02:48:30 2024 CET Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 9 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 854178 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- GLFPIO+Calibri Type 1C WinAnsi yes yes no 386 0 GLGBCF+CalibriItalic Type 1C WinAnsi yes yes no 385 0 GLGBCG+CalibriItalic+20 Type 1C WinAnsi yes yes no 369 0 GLGBCH+Calibri+fb Type 1C Custom yes yes yes 398 0 GLGBCI+Calibri+20 Type 1C WinAnsi yes yes no 400 0 GLGBDJ+CalibriBold Type 1C WinAnsi yes yes no 391 0 GLGBEJ+TimesNewRomanUnic+22 Type 1C Custom yes yes yes 200 0 GLGBEK+TeXCMMathsItalic Type 1C WinAnsi yes yes no 209 0 GLGJDM+Humanist777BTUnicRomanB Type 1C WinAnsi yes yes no 57 0 GLGJDN+Humanist777BTUnicRomanB+fb Type 1C Custom yes yes yes 60 0 GLGJDO+Humanist777BTUnicRomanB+20 Type 1C WinAnsi yes yes no 61 0 GLGJDP+Humanist777BTUnicItalicB Type 1C WinAnsi yes yes no 78 0 GLGJCL+Humanist777BTUnicBoldB Type 1C WinAnsi yes yes no 56 0 GLGLKB+CalibriBold+fb Type 1C Custom yes yes yes 84 0 GLGLMB+AdvTTf696b0bf.B Type 1C WinAnsi yes yes no 143 0 GLGLMC+CharterITCUnic Type 1C WinAnsi yes yes no 203 0 GLGLMD+CharterITCUnicItalic Type 1C WinAnsi yes yes no 216 0 GLGLME+CharterITCUnic+20 Type 1C WinAnsi yes yes no 117 0 GLGLMF+CharterITCUnicBold Type 1C WinAnsi yes yes no 206 0 GLGLMG+CharterITCUnic+fb Type 1C Custom yes yes yes 208 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-07-06 02:47:01 CEST RepresentationInformation: pmc_10966234.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-07-05 02:35:37 CEST Size: 854178 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 402 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Role of vericiguat in management of patients with heart failure with reduced ejection fraction after worsening episode Destination: maintitle Item: Title: Introduction Destination: sectionehf214647-sec-0001 Item: Title: Need for a comprehensive treatment of patients with heart failure with reduced ejection fraction Destination: sectionehf214647-sec-0002 Item: Title: Role of vericiguat in „post„‐„event management in heart failure with reduced ejection fraction Destination: sectionehf214647-sec-0003 Item: Title: Practical aspects of vericiguat Destination: sectionehf214647-sec-0004 Item: Title: Vericiguat and current guidelines Destination: sectionehf214647-sec-0005 Item: Title: Expert opinion Destination: sectionehf214647-sec-0006 Item: Title: Conclusions Destination: sectionehf214647-sec-0007 Item: Title: Lay summary Destination: sectionehf214647-sec-0008 Item: Title: Acknowledgements Destination: sectionehf214647-sec-0009 Item: Title: Conflict of interest Destination: sectionehf214647-sec-0010 Item: Title: References Destination: ref_title Info: Title: Role of vericiguat in management of patients with heart failure with reduced ejection fraction after worsening episode Author: Aleix Olivella, Luis Almenar‐Bonet, Pedro Moliner, Emmanuel Coloma, Antoni Martínez‐Rubio, Marco Paz Bermejo, Ramon Boixeda, German Cediel, Ana Belén Méndez Fernández, Lorenzo Facila Rubio Subject: Keywords: 10.1002/ehf2.14647 and Heart failure; Sacubitril valsartan; SGLT2; Vericiguat; Worsening Creator: Arbortext Advanced Print Publisher 9.1.520/W Unicode Producer: Acrobat Distiller 23.0 (Windows) CreationDate: Wed Mar 20 11:44:19 CET 2024 ModDate: Mon Mar 25 02:48:30 CET 2024 Trapped: False ID: 0x2a0fb19bf7660b5ff3e77831e7fa1ee2, 0xae0a22c6ffa328b5cc4750bd7a0d23d6 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 46 ImageHeight: 45 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1536 ImageHeight: 956 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1654 ImageHeight: 1199 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1477 ImageHeight: 980 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1421 ImageHeight: 1031 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: Perceptual Fonts: Type1: Font: BaseFont: GLGBCF+CalibriItalic FontSubset: true FirstChar: 40 LastChar: 243 FontDescriptor: FontName: GLGBCF+CalibriItalic Flags: Serif, Nonsymbolic, Italic FontBBox: -104, -187, 937, 843 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GLFPIO+Calibri FontSubset: true FirstChar: 37 LastChar: 237 FontDescriptor: FontName: GLFPIO+Calibri Flags: Serif, Nonsymbolic FontBBox: -93, -187, 854, 843 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GLGBDJ+CalibriBold FontSubset: true FirstChar: 45 LastChar: 121 FontDescriptor: FontName: GLGBDJ+CalibriBold Flags: Nonsymbolic FontBBox: -83, -187, 875, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GLGBEJ+TimesNewRomanUnic+22 FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: GLGBEJ+TimesNewRomanUnic+22 Flags: Symbolic FontBBox: -41, -270, 1177, 1020 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: GLGLMC+CharterITCUnic FontSubset: true FirstChar: 40 LastChar: 248 FontDescriptor: FontName: GLGLMC+CharterITCUnic Flags: Serif, Nonsymbolic FontBBox: -218, -229, 937, 958 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GLGBCH+Calibri+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: GLGBCH+Calibri+fb Flags: Symbolic FontBBox: -114, -302, 906, 885 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: GLGJDP+Humanist777BTUnicItalicB FontSubset: true FirstChar: 83 LastChar: 117 FontDescriptor: FontName: GLGJDP+Humanist777BTUnicItalicB Flags: Nonsymbolic, Italic FontBBox: -218, -229, 1000, 968 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GLGLMF+CharterITCUnicBold FontSubset: true FirstChar: 48 LastChar: 57 FontDescriptor: FontName: GLGLMF+CharterITCUnicBold Flags: Nonsymbolic FontBBox: -218, -229, 937, 958 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GLGLMB+AdvTTf696b0bf.B FontSubset: true FirstChar: 82 LastChar: 115 FontDescriptor: FontName: GLGLMB+AdvTTf696b0bf.B Flags: Nonsymbolic FontBBox: -218, -218, 947, 916 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GLGBCI+Calibri+20 FontSubset: true FirstChar: 150 LastChar: 150 FontDescriptor: FontName: GLGBCI+Calibri+20 Flags: Nonsymbolic FontBBox: -208, -229, 1041, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GLGLMG+CharterITCUnic+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: GLGLMG+CharterITCUnic+fb Flags: Symbolic FontBBox: 0, 0, 864, 739 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: GLGBCG+CalibriItalic+20 FontSubset: true FirstChar: 146 LastChar: 146 FontDescriptor: FontName: GLGBCG+CalibriItalic+20 Flags: Nonsymbolic, Italic FontBBox: -208, -229, 1041, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GLGBEK+TeXCMMathsItalic FontSubset: true FirstChar: 60 LastChar: 62 FontDescriptor: FontName: GLGBEK+TeXCMMathsItalic Flags: Nonsymbolic, Italic FontBBox: -31, -239, 1041, 750 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GLGLKB+CalibriBold+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: GLGLKB+CalibriBold+fb Flags: Symbolic FontBBox: -125, -302, 979, 937 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: GLGLME+CharterITCUnic+20 FontSubset: true FirstChar: 146 LastChar: 151 FontDescriptor: FontName: GLGLME+CharterITCUnic+20 Flags: Nonsymbolic FontBBox: -218, -156, 1552, 718 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GLGJCL+Humanist777BTUnicBoldB FontSubset: true FirstChar: 49 LastChar: 108 FontDescriptor: FontName: GLGJCL+Humanist777BTUnicBoldB Flags: Nonsymbolic FontBBox: -41, -229, 947, 979 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GLGLMD+CharterITCUnicItalic FontSubset: true FirstChar: 40 LastChar: 121 FontDescriptor: FontName: GLGLMD+CharterITCUnicItalic Flags: Serif, Nonsymbolic, Italic FontBBox: -218, -229, 947, 947 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GLGJDM+Humanist777BTUnicRomanB FontSubset: true FirstChar: 42 LastChar: 122 FontDescriptor: FontName: GLGJDM+Humanist777BTUnicRomanB Flags: Nonsymbolic FontBBox: -218, -229, 947, 968 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: GLGJDN+Humanist777BTUnicRomanB+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: GLGJDN+Humanist777BTUnicRomanB+fb Flags: Symbolic FontBBox: 19, 0, 822, 750 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: GLGJDO+Humanist777BTUnicRomanB+20 FontSubset: true FirstChar: 150 LastChar: 150 FontDescriptor: FontName: GLGJDO+Humanist777BTUnicRomanB+20 Flags: Nonsymbolic FontBBox: -218, -114, 1614, 718 FontFile3: true Encoding: WinAnsiEncoding XMP: VoR10.1002/ehf2.14647 Pages: Page: Label: 628 Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 113, 561, 123, 572 Destination: 346 Annotation: Subtype: Link Rect: 216, 561, 227, 572 Destination: 346 Annotation: Subtype: Link Rect: 297, 561, 313, 572 Destination: 346 Annotation: Subtype: Link Rect: 403, 561, 414, 572 Destination: 346 Annotation: Subtype: Link Rect: 521, 561, 532, 572 Destination: 346 Annotation: Subtype: Link Rect: 143, 547, 151, 558 Destination: 346 Annotation: Subtype: Link Rect: 227, 547, 245, 558 Destination: 346 Annotation: Subtype: Link Rect: 318, 547, 332, 558 Destination: 346 Annotation: Subtype: Link Rect: 472, 547, 476, 558 Destination: 346 Annotation: Subtype: Link Rect: 148, 533, 156, 544 Destination: 346 Annotation: Subtype: Link Rect: 163, 531, 173, 541 Annotation: Subtype: Link Rect: 75, 207, 127, 214 Annotation: Subtype: Link Rect: 161, 111, 169, 120 Destination: 94 Annotation: Subtype: Link Rect: 93, 87, 97, 96 Destination: 94 Annotation: Subtype: Link Rect: 358, 135, 361, 144 Destination: 94 Annotation: Subtype: Link Rect: 530, 123, 539, 132 Destination: 94 Annotation: Subtype: Link Rect: 529, 99, 538, 108 Destination: 94 Annotation: Subtype: Link Rect: 206, 33, 368, 40 Thumb: true Page: Label: 629 Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 169, 658, 178, 667 Destination: 94 Annotation: Subtype: Link Rect: 128, 598, 132, 607 Destination: 94 Annotation: Subtype: Link Rect: 187, 562, 204, 571 Destination: 94 Annotation: Subtype: Link Rect: 274, 514, 281, 523 Destination: 94 Annotation: Subtype: Link Rect: 279, 502, 291, 511 Destination: 94 Annotation: Subtype: Link Rect: 250, 286, 266, 295 Destination: 94 Annotation: Subtype: Link Rect: 223, 226, 239, 235 Destination: 94 Annotation: Subtype: Link Rect: 141, 190, 157, 199 Destination: 94 Annotation: Subtype: Link Rect: 156, 154, 174, 163 Destination: 94 Annotation: Subtype: Link Rect: 256, 82, 291, 91 Destination: 94 Annotation: Subtype: Link Rect: 348, 682, 365, 691 Destination: 94 Annotation: Subtype: Link Rect: 423, 622, 439, 631 Destination: 94 Annotation: Subtype: Link Rect: 462, 586, 478, 595 Destination: 94 Annotation: Subtype: Link Rect: 335, 430, 342, 439 Destination: 153 Annotation: Subtype: Link Rect: 481, 310, 488, 319 Destination: 153 Annotation: Subtype: Link Rect: 505, 178, 520, 187 Destination: 153 Annotation: Subtype: Link Rect: 332, 70, 348, 79 Destination: 94 Thumb: true Page: Label: 630 Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 194, 550, 221, 559 Destination: 94 Annotation: Subtype: Link Rect: 124, 514, 132, 523 Destination: 94 Annotation: Subtype: Link Rect: 255, 426, 259, 435 Destination: 21 Annotation: Subtype: Link Rect: 265, 430, 291, 439 Destination: 94 Annotation: Subtype: Link Rect: 122, 370, 129, 379 Destination: 153 Annotation: Subtype: Link Rect: 332, 490, 339, 499 Destination: 153 Annotation: Subtype: Link Rect: 496, 430, 517, 439 Destination: 94 Annotation: Subtype: Link Rect: 326, 370, 333, 379 Destination: 153 Thumb: true Page: Label: 631 Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 110, 694, 126, 703 Destination: 153 Annotation: Subtype: Link Rect: 84, 557, 89, 567 Destination: 33 Annotation: Subtype: Link Rect: 94, 562, 128, 571 Destination: 94 Annotation: Subtype: Link Rect: 89, 526, 96, 535 Destination: 153 Annotation: Subtype: Link Rect: 450, 610, 457, 619 Destination: 153 Annotation: Subtype: Link Rect: 353, 502, 360, 511 Destination: 153 Annotation: Subtype: Link Rect: 415, 478, 431, 487 Destination: 94 Thumb: true Page: Label: 632 Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 268, 582, 273, 591 Destination: 44 Annotation: Subtype: Link Rect: 81, 569, 85, 579 Destination: 54 Annotation: Subtype: Link Rect: 115, 550, 118, 559 Destination: 94 Annotation: Subtype: Link Rect: 129, 406, 137, 415 Destination: 153 Annotation: Subtype: Link Rect: 412, 646, 420, 655 Destination: 153 Annotation: Subtype: Link Rect: 357, 574, 391, 583 Destination: 94 Thumb: true Page: Label: 633 Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 175, 706, 182, 715 Destination: 153 Annotation: Subtype: Link Rect: 221, 646, 228, 655 Destination: 153 Annotation: Subtype: Link Rect: 399, 694, 406, 703 Destination: 153 Annotation: Subtype: Link Rect: 464, 634, 471, 643 Destination: 153 Annotation: Subtype: Link Rect: 522, 622, 529, 631 Destination: 153 Annotation: Subtype: Link Rect: 532, 391, 537, 399 Destination: 94 Thumb: true Page: Label: 634 Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 220, 654, 225, 663 Destination: 54 Annotation: Subtype: Link Rect: 230, 658, 237, 667 Destination: 153 Annotation: Subtype: Link Rect: 147, 622, 154, 631 Destination: 153 Annotation: Subtype: Link Rect: 170, 586, 178, 595 Destination: 153 Annotation: Subtype: Link Rect: 127, 526, 134, 535 Destination: 153 Annotation: Subtype: Link Rect: 194, 514, 201, 523 Destination: 153 Annotation: Subtype: Link Rect: 284, 430, 291, 439 Destination: 94 Thumb: true Page: Label: 635 Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 164, 637, 209, 645 Annotation: Subtype: Link Rect: 70, 628, 140, 636 Annotation: Subtype: Link Rect: 179, 601, 209, 609 Annotation: Subtype: Link Rect: 71, 592, 159, 600 Annotation: Subtype: Link Rect: 124, 529, 209, 537 Annotation: Subtype: Link Rect: 71, 520, 108, 528 Annotation: Subtype: Link Rect: 177, 457, 209, 465 Annotation: Subtype: Link Rect: 71, 448, 116, 456 Annotation: Subtype: Link Rect: 178, 385, 209, 393 Annotation: Subtype: Link Rect: 71, 376, 141, 384 Annotation: Subtype: Link Rect: 125, 313, 184, 321 Annotation: Subtype: Link Rect: 143, 259, 209, 267 Annotation: Subtype: Link Rect: 70, 250, 100, 258 Annotation: Subtype: Link Rect: 117, 196, 181, 204 Annotation: Subtype: Link Rect: 179, 115, 209, 123 Annotation: Subtype: Link Rect: 71, 106, 155, 114 Annotation: Subtype: Link Rect: 249, 673, 372, 681 Annotation: Subtype: Link Rect: 236, 664, 253, 672 Annotation: Subtype: Link Rect: 249, 610, 338, 618 Annotation: Subtype: Link Rect: 291, 547, 355, 555 Annotation: Subtype: Link Rect: 249, 511, 349, 519 Annotation: Subtype: Link Rect: 314, 484, 374, 492 Annotation: Subtype: Link Rect: 236, 475, 249, 483 Annotation: Subtype: Link Rect: 324, 421, 374, 429 Annotation: Subtype: Link Rect: 236, 412, 279, 420 Annotation: Subtype: Link Rect: 342, 358, 374, 366 Annotation: Subtype: Link Rect: 236, 349, 286, 357 Annotation: Subtype: Link Rect: 292, 304, 374, 312 Annotation: Subtype: Link Rect: 235, 295, 270, 303 Annotation: Subtype: Link Rect: 344, 259, 374, 267 Annotation: Subtype: Link Rect: 236, 250, 320, 258 Annotation: Subtype: Link Rect: 249, 178, 339, 186 Annotation: Subtype: Link Rect: 303, 124, 374, 132 Annotation: Subtype: Link Rect: 236, 115, 281, 123 Annotation: Subtype: Link Rect: 508, 673, 539, 681 Annotation: Subtype: Link Rect: 401, 664, 486, 672 Annotation: Subtype: Link Rect: 414, 592, 455, 600 Annotation: Subtype: Link Rect: 401, 583, 495, 591 Annotation: Subtype: Link Rect: 458, 520, 539, 528 Annotation: Subtype: Link Rect: 401, 511, 419, 519 Annotation: Subtype: Link Rect: 414, 466, 515, 474 Annotation: Subtype: Link Rect: 414, 430, 538, 438 Annotation: Subtype: Link Rect: 401, 421, 419, 429 Annotation: Subtype: Link Rect: 414, 367, 530, 375 Annotation: Subtype: Link Rect: 413, 331, 528, 339 Annotation: Subtype: Link Rect: 521, 259, 539, 267 Annotation: Subtype: Link Rect: 401, 250, 481, 258 Annotation: Subtype: Link Rect: 485, 178, 539, 186 Annotation: Subtype: Link Rect: 401, 169, 462, 177 Annotation: Subtype: Link Rect: 414, 115, 500, 123 Thumb: true Page: Label: 636 Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 178, 696, 209, 704 Annotation: Subtype: Link Rect: 71, 687, 155, 695 Annotation: Subtype: Link Rect: 178, 642, 209, 650 Annotation: Subtype: Link Rect: 71, 633, 130, 641 Annotation: Subtype: Link Rect: 186, 597, 209, 605 Annotation: Subtype: Link Rect: 71, 588, 154, 596 Annotation: Subtype: Link Rect: 178, 543, 209, 551 Annotation: Subtype: Link Rect: 71, 534, 130, 542 Annotation: Subtype: Link Rect: 121, 489, 179, 497 Annotation: Subtype: Link Rect: 102, 426, 207, 434 Annotation: Subtype: Link Rect: 178, 381, 209, 389 Annotation: Subtype: Link Rect: 70, 372, 129, 380 Annotation: Subtype: Link Rect: 187, 318, 209, 326 Annotation: Subtype: Link Rect: 71, 309, 142, 317 Annotation: Subtype: Link Rect: 178, 255, 209, 263 Annotation: Subtype: Link Rect: 71, 246, 140, 254 Annotation: Subtype: Link Rect: 177, 201, 209, 209 Annotation: Subtype: Link Rect: 71, 192, 150, 200 Annotation: Subtype: Link Rect: 305, 705, 374, 713 Annotation: Subtype: Link Rect: 235, 696, 257, 704 Annotation: Subtype: Link Rect: 249, 642, 339, 650 Annotation: Subtype: Link Rect: 291, 570, 370, 578 Annotation: Subtype: Link Rect: 250, 489, 352, 497 Annotation: Subtype: Link Rect: 340, 426, 374, 434 Annotation: Subtype: Link Rect: 236, 417, 294, 425 Annotation: Subtype: Link Rect: 343, 345, 374, 353 Annotation: Subtype: Link Rect: 236, 336, 322, 344 Annotation: Subtype: Link Rect: 299, 300, 374, 308 Annotation: Subtype: Link Rect: 235, 291, 369, 299 Annotation: Subtype: Link Rect: 235, 282, 374, 290 Annotation: Subtype: Link Rect: 235, 273, 275, 281 Annotation: Subtype: Link Rect: 249, 111, 325, 119 Annotation: Subtype: Link Rect: 505, 669, 539, 677 Annotation: Subtype: Link Rect: 401, 660, 472, 668 Annotation: Subtype: Link Rect: 414, 579, 503, 587 Annotation: Subtype: Link Rect: 516, 525, 539, 533 Annotation: Subtype: Link Rect: 401, 516, 480, 524 Annotation: Subtype: Link Rect: 414, 462, 505, 470 Annotation: Subtype: Link Rect: 414, 408, 504, 416 Annotation: Subtype: Link Rect: 455, 336, 519, 344 Annotation: Subtype: Link Rect: 414, 273, 523, 281 Annotation: Subtype: Link Rect: 413, 192, 477, 200 Annotation: Subtype: Link Rect: 456, 129, 526, 137 Thumb: true Checksum: 3ceb7849 Type: CRC32 Checksum: e7da749858b13642025834345d96c9ad Type: MD5 Checksum: f98e8b224f8e9c233b98e7694d1d08e74a51c8ee Type: SHA-1 Checksum: 528fcc917efeb8b10d6161414d79ecc9b8be4c2f4904c1052713833d66480a03 Type: SHA-256