a3808add05980bd0cde9b7f6d1b9bf6b pmc_9858179.pdf 9f52fce167fa68e486169e70ae6ef6897ad1f27b pmc_9858179.pdf c0aa18f19adb57af0ddb9c9c3b75093e320679f195274b6968cc30993273ed42 pmc_9858179.pdf Title: Thorough Characterization of ETHQB3.5, a QTL Involved in Melon Fruit Climacteric Behavior and Aroma Volatile Composition Subject: The effect of the QTL involved in climacteric ripening ETHQB3.5 on the fruit VOC composition was studied using a set of Near-Isogenic Lines (NILs) containing overlapping introgressions from the Korean accession PI 16375 on the chromosome 3 in the climacteric ‘Piel de Sapo’ (PS) genetic background. ETHQB3.5 was mapped in an interval of 1.24 Mb that contained a NAC transcription factor. NIL fruits also showed differences in VOC composition belonging to acetate esters, non-acetate esters, and sulfur-derived families. Cosegregation of VOC composition (23 out of 48 total QTLs were mapped) and climacteric ripening was observed, suggesting a pleiotropic effect of ETHQB3.5. On the other hand, other VOCs (mainly alkanes, aldehydes, and ketones) showed a pattern of variation independent of ETHQB3.5 effects, indicating the presence of other genes controlling non-climacteric ripening VOCs. Network correlation analysis and hierarchical clustering found groups of highly correlated compounds and confirmed the involvement of the climacteric differences in compound classes and VOC differences. The modification of melon VOCs may be achieved with or without interfering with its physiological behavior, but it is likely that high relative concentrations of some type of ethylene-dependent esters could be achieved in climacteric cultivars. Keywords: candidate genes; Cucumis melo L.; ethylene production; fruit quality; near-isogenic lines; respiration rate; quantitative trait loci; volatile organic compounds Author: Noelia Dos-Santos, María C. Bueso, Aurora Díaz, Eduard Moreno, Jordi Garcia-Mas, Antonio J. Monforte and Juan Pablo Fernández-Trujillo Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Mon Jan 16 04:16:07 2023 CET ModDate: Mon Jan 16 04:29:01 2023 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 36 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 6168894 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- IYDCBB+VnURWPalladioL Type 1 Custom yes yes no 10 0 PVZWEF+URWPalladioL-Bold Type 1 Custom yes yes no 15 0 XVUPAL+URWPalladioL-Roma Type 1 Custom yes yes no 20 0 RNYBWG+URWPalladioL-Ital Type 1 Custom yes yes no 24 0 JPIQBG+URWPalladioL-BoldItal Type 1 Custom yes yes no 28 0 SSNIUI+VnURWPalladioL-Bold Type 1 Custom yes yes no 32 0 XBNVAE+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 50 0 NTJMOU+CMSY10 Type 1 Builtin yes yes no 75 0 GBCLNF+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 86 0 GBCLNH+PalatinoLinotype TrueType WinAnsi yes yes no 89 0 GBCLOJ+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 92 0 GBCLNF+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 112 0 GBCLNG+PalatinoLinotype CID TrueType Identity-H yes yes yes 115 0 GBCLNH+PalatinoLinotype TrueType WinAnsi yes yes no 121 0 GBCLOJ+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 124 0 KSMUYF+MSAM10 Type 1 Builtin yes yes no 131 0 GBCLNF+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 146 0 GBCLNG+PalatinoLinotype CID TrueType Identity-H yes yes yes 149 0 GBCLNH+PalatinoLinotype TrueType WinAnsi yes yes no 155 0 GBCLOJ+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 158 0 GBDCLC+SimSun CID TrueType Identity-H yes yes yes 161 0 HYYHEA+CMBSY10 Type 1 Builtin yes yes no 195 0 GBCLNF+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 221 0 GBCLNH+PalatinoLinotype TrueType WinAnsi yes yes no 224 0 GBCLOJ+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 227 0 GBCLNF+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 242 0 GBCLNH+PalatinoLinotype TrueType WinAnsi yes yes no 245 0 GBCLOJ+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 248 0 GBCLNF+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 264 0 GBCLNH+PalatinoLinotype TrueType WinAnsi yes yes no 267 0 GBCLOJ+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 270 0 GBCLNF+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 289 0 GBCLNH+PalatinoLinotype TrueType WinAnsi yes yes no 292 0 GBCLOJ+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 295 0 GBCLNF+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 310 0 GBCLNH+PalatinoLinotype TrueType WinAnsi yes yes no 313 0 GBCLOJ+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 316 0 CBSRZX+EURM10 Type 1 Builtin yes yes no 332 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-11-11 02:31:40 CET RepresentationInformation: pmc_9858179.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-02-02 03:40:09 CET Size: 6168894 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 880 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4d3167f4 Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@ed9d034 Children: Item: Title: Plant Materials, Crop Management, and Experimental Design Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Item: Title: Physiological Behavior and Maturity Indices at Harvest Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Item: Title: Juice Sampling and VOC Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: Candidate Gene Selection Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: Statistical Analysis and QTL Mapping Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Classification of VOCs According to Ethylene Dependence Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Children: Item: Title: Ideogram of the NILs. Physiological Behavior, Mapping of ETHQB3.5 and Putative Candidate Genes Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Volatile Organic Compounds Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Children: Item: Title: Compound Classes of VOCs and Univariate Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Univariate Analysis of Individual VOCs Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Genes Located in the Region Mapped of ETHQB3.5 or Covered by the Introgression Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: VOC QTL Mapping Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: Correlation Network and Hierarchical Clustering Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Association between VOCs and Climacteric Behavior Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Info: Title: Thorough Characterization of ETHQB3.5, a QTL Involved in Melon Fruit Climacteric Behavior and Aroma Volatile Composition Author: Noelia Dos-Santos, María C. Bueso, Aurora Díaz, Eduard Moreno, Jordi Garcia-Mas, Antonio J. Monforte and Juan Pablo Fernández-Trujillo Subject: The effect of the QTL involved in climacteric ripening ETHQB3.5 on the fruit VOC composition was studied using a set of Near-Isogenic Lines (NILs) containing overlapping introgressions from the Korean accession PI 16375 on the chromosome 3 in the climacteric ‘Piel de Sapo’ (PS) genetic background. ETHQB3.5 was mapped in an interval of 1.24 Mb that contained a NAC transcription factor. NIL fruits also showed differences in VOC composition belonging to acetate esters, non-acetate esters, and sulfur-derived families. Cosegregation of VOC composition (23 out of 48 total QTLs were mapped) and climacteric ripening was observed, suggesting a pleiotropic effect of ETHQB3.5. On the other hand, other VOCs (mainly alkanes, aldehydes, and ketones) showed a pattern of variation independent of ETHQB3.5 effects, indicating the presence of other genes controlling non-climacteric ripening VOCs. Network correlation analysis and hierarchical clustering found groups of highly correlated compounds and confirmed the involvement of the climacteric differences in compound classes and VOC differences. The modification of melon VOCs may be achieved with or without interfering with its physiological behavior, but it is likely that high relative concentrations of some type of ethylene-dependent esters could be achieved in climacteric cultivars. 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