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Title:           Targeting macrophages with phosphatidylserine-rich liposomes as a potential antigen-specific immunotherapy for type 1 diabetes
Subject:         Journal of Autoimmunity, 145 (2024) 103196. doi:10.1016/j.jaut.2024.103196
Author:          Ivan Garcia-Loza
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      Title: Targeting macrophages with phosphatidylserine-rich liposomes as a potential antigen-specific immunotherapy for type 1 diabetes
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        Title: 1 Introduction
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        Title: 2 Material and methods
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          Title: 2.1 Liposome manufacturing
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          Title: 2.2 Mice
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          Title: 2.3 In vivo capture of fluorescent PS-liposomes in NOD mice
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          Title: 2.4 Subjects
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          Title: 2.5 In vitro macrophage differentiation
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          Title: 2.6 PS-liposome uptake assay
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          Title: 2.7 Monitoring of MoMϕ viability
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          Title: 2.8 Confocal microscopy imaging
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          Title: 2.10 Luminex® and enzyme-linked immunosorbent assay (ELISA)
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          Title: 3.1 Murine splenic and hepatic Mϕ are the most in vivo phagocytic cells of PS-liposomes
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          Title: 3.2 The phagocytic function remains intact in MoMϕ from patients with T1D
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          Title: 3.3 PS-liposome internalisation does not impact MoMϕ viability
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          Title: 3.4 MoMϕ expression of phenotypic markers is altered in T1D subjects
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          Title: 3.5 Aberrant response to inflammatory stimuli in M–CSF–driven MoMϕ is a T1D oddity
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          Title: 3.6 PS-liposomes selectively modulate the immunoregulatory phenotype of non-inflammatory Mϕ
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          Title: 3.7 PS-liposome uptake selectively impacts the cytokine profile of inflammatory M1-MoMϕ towards tolerance
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          Title: 3.8 PS-liposomeINS exposure of inflammatory M1-MoMϕ modulates CD4+ and CD8+ T cell responses in the context of autoantigen  ...
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        Title: 4 Discussion
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        Title: 5 Conclusions
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        Title: Ethics statement
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        Title: Funding
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        Title: Contribution to the field statement
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        Title: CRediT authorship contribution statement
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        Title: Declaration of competing interest
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        Title: Data availability
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        Title: Acknowledgements
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        Title: Abbreviations
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        Title: Appendix A Supplementary data
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   Type: CRC32
  Checksum: 1afde5d4af25129d5f0dee8ffd63af3a
   Type: MD5
  Checksum: b9c04f22bb0445e58d6fcd47901706406f2df894
   Type: SHA-1
  Checksum: 90fd042aca9d9ee6c5ace17b79c18b74c618fc50a19b48ce792efefbd163c15a
   Type: SHA-256