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Title:           Time-dependent ligand-receptor binding kinetics and functionality in a heterodimeric receptor model
Subject:         Biochemical Pharmacology, 225 (2024) 116299. doi:10.1016/j.bcp.2024.116299
Keywords:        Binding kinetics,Receptor heterodimerization,Drug combination therapy,Mathematical modeling,Dynamical systems
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      Title: Time-dependent ligand-receptor binding kinetics and functionality in a heterodimeric receptor model
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        Title: 1 Introduction
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        Title: 2 Methods
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        Title: 3 Results
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          Title: 3.1 Case 1: Both ligands are in excess with respect to the total receptor concentration
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            Title: 3.1.1 Bivalent ligands
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          Title: 3.2 Case 2: Only one ligand (B) is in excess with respect to the total receptor concentration
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            Title: 3.2.1 The ligand that is not in excess is an endogenous ligand
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          Title: CRediT authorship contribution statement
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        Title: Declaration of competing interest
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        Title: Data availability
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        Title: Acknowledgements
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        Title: Appendix A Uniqueness and stability of the equilibrium for case 1
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        Title: Appendix B Equilibria and their stability character for a specific example of case 2
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        Title: Appendix C Existence of a unique biologically plausible equilibrium point
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        Title: References
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  Checksum: 35829623
   Type: CRC32
  Checksum: 611caeda335305d8a05f4ff510562a26
   Type: MD5
  Checksum: ffdf2679d6f3a88c8a67a366bc292cd780e5429f
   Type: SHA-1
  Checksum: 0cf37fabe43a67923da06c3c0423926b2c9241f7af618eb0a89fd4ca5f75d207
   Type: SHA-256