4a691c0cdc481a6ee9e000785bc7a537  cheeurjou_a2024m5pe202401165.pdf
c36edc8e2c46fedbbb3ce8271dc2af32be3b892e  cheeurjou_a2024m5pe202401165.pdf
0424adfbf03a228711b89cddba2b19df4c1fe74282b5ee938f50381c2b74175c  cheeurjou_a2024m5pe202401165.pdf

Title:           Rationalization of a Streptavidin Based Enantioselective Artificial Suzukiase: An Integrative Computational Approach
Subject:         Chemistry A European J 0.0:e202401165
Creator:         ima-server®
Producer:        PDFlib+PDI 9.0.7p3 (C++/Win64); modified using iText 4.2.0 by 1T3XT
CreationDate:    Tue Jun  4 13:21:39 2024 CEST
ModDate:         Wed Jul 10 16:53:06 2024 CEST
Custom Metadata: yes
Metadata Stream: yes
Tagged:          no
UserProperties:  no
Suspects:        no
Form:            none
JavaScript:      no
Pages:           14
Encrypted:       no
Page size:       595.276 x 841.89 pts (A4)
Page rot:        0
File size:       2315079 bytes
Optimized:       no
PDF version:     1.6


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
ZGAHVZ+Publico-Medium                Type 1C           Custom           yes yes yes     50  0
ADVPPD+MyriadPro-Semibold            Type 1C           Custom           yes yes yes     52  0
VQZKVW+MyriadPro-Regular             Type 1C           Custom           yes yes yes     53  0
WLSAFM+MyriadPro-It                  Type 1C           Custom           yes yes yes     54  0
TeX_CM_Maths_Symbols                 Type 1            Builtin          yes no  yes     55  0
TeX_CM_Roman                         Type 1            Builtin          yes no  yes     65  0
HelveticaNeue-Bold                   Type 1            Builtin          yes no  yes     56  0
QBXUTB+PublicoHeadline-Light         Type 1C           Custom           yes yes yes     57  0
BNSASD+Publico-Medium                Type 1            Custom           yes yes no     133  0
TKZZVR+TimesNewRomanPSMT             CID TrueType      Identity-H       yes yes yes     51  0
Times-Roman                          Type 1            WinAnsi          no  no  no       5  0
LPFFIY+ArialMT                       CID TrueType      Identity-H       yes yes yes     64  0
TimesTenIMGreekUpright               Type 1            Builtin          yes no  yes     70  0
RBSHKS+MyriadPro-SemiboldIt          Type 1C           Custom           yes yes yes     79  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2024-07-11 02:46:17 CEST
 RepresentationInformation: cheeurjou_a2024m5pe202401165.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2024-07-10 16:54:23 CEST
  Size: 2315079
  Format: PDF
  Version: 1.6
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  PDFMetadata: 
   Objects: 0
   FreeObjects: 2
   IncrementalUpdates: 0
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseOutlines
    Outlines: 
     Item: 
      Title: Rationalization of a Streptavidin Based Enantioselective Artificial Suzukiase꞉ An Integrative Computational Approach
      Destination: BookMarkRationalizationofaStreptavidinBasedEnan
      Children: 
       Item: 
        Title: Introduction
        Destination: BookMarkIntroduction2
       Item: 
        Title: Methodology
        Destination: BookMarkMethodology3
       Item: 
        Title: Results and Discussion
        Destination: BookMarkResultsandDiscussion4
        Children: 
         Item: 
          Title: Studying the Reaction in Water with DFT
          Destination: BookMarkStudyingtheReactioninWaterwithDFT5
         Item: 
          Title: Molecular Modeling of the Protein Systems
          Destination: BookMarkMolecularModelingoftheProteinSystems6
          Children: 
           Item: 
            Title: Docking and MD Simulations with Precatalytic Cofactors
            Destination: BookMarkDockingandMDSimulationswithPrecatalytic
           Item: 
            Title: Docking of OA Intermediates
            Destination: BookMarkDockingofOAIntermediates8
           Item: 
            Title: MD Simulations of OA Intermediates
            Destination: BookMarkMDSimulationsofOAIntermediates9
           Item: 
            Title: MD Simulations with RE-TS
            Destination: BookMarkMDSimulationswithRE-TS10
       Item: 
        Title: Conclusions
        Destination: BookMarkConclusions11
       Item: 
        Title: Supporting Information
        Destination: BookMarkSupportingInformation12
       Item: 
        Title: Acknowledgements
        Destination: BookMarkAcknowledgements13
       Item: 
        Title: Conflict of Interests
        Destination: BookMarkConflictofInterests14
       Item: 
        Title: Data Availability Statement
        Destination: BookMarkDataAvailabilityStatement15
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 228
      ImageHeight: 45
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 157
      ImageHeight: 147
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 383
      ImageHeight: 374
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 684
      ImageHeight: 698
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 228
      ImageHeight: 45
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 657
      ImageHeight: 453
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 663
      ImageHeight: 432
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 744
      ImageHeight: 520
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1533
      ImageHeight: 689
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 716
      ImageHeight: 750
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1520
      ImageHeight: 817
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 702
      ImageHeight: 982
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 736
      ImageHeight: 1243
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 743
      ImageHeight: 633
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1533
      ImageHeight: 1864
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 157
      ImageHeight: 147
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 3288
      ImageHeight: 1708
      BitsPerSample: 8
      BitsPerSampleUnit: integer
   Fonts: 
    Type0: 
     Font: 
      BaseFont: LPFFIY+ArialMT
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: TKZZVR+TimesNewRomanPSMT
      Encoding: Identity-H
      ToUnicode: true
    Type1: 
     Font: 
      BaseFont: TeX_CM_Roman
      FirstChar: 1
      LastChar: 127
      FontDescriptor: 
       FontName: TeX_CM_Roman
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
     Font: 
      BaseFont: ZGAHVZ+Publico-Medium
      FontSubset: true
      FirstChar: 1
      LastChar: 17
      FontDescriptor: 
       FontName: ZGAHVZ+Publico-Medium
       Flags: Nonsymbolic
       FontBBox: -135, -210, 1111, 906
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: ADVPPD+MyriadPro-Semibold
      FontSubset: true
      FirstChar: 1
      LastChar: 56
      FontDescriptor: 
       FontName: ADVPPD+MyriadPro-Semibold
       Flags: Nonsymbolic
       FontBBox: -161, -250, 1198, 972
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: VQZKVW+MyriadPro-Regular
      FontSubset: true
      FirstChar: 1
      LastChar: 95
      FontDescriptor: 
       FontName: VQZKVW+MyriadPro-Regular
       Flags: Nonsymbolic
       FontBBox: -157, -250, 1126, 952
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: WLSAFM+MyriadPro-It
      FontSubset: true
      FirstChar: 1
      LastChar: 73
      FontDescriptor: 
       FontName: WLSAFM+MyriadPro-It
       Flags: Nonsymbolic, Italic
       FontBBox: -185, -250, 1090, 953
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: TimesTenIMGreekUpright
      FirstChar: 23
      LastChar: 251
      FontDescriptor: 
       FontName: TimesTenIMGreekUpright
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
     Font: 
      BaseFont: TeX_CM_Maths_Symbols
      FirstChar: 1
      LastChar: 138
      FontDescriptor: 
       FontName: TeX_CM_Maths_Symbols
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
     Font: 
      BaseFont: HelveticaNeue-Bold
      FirstChar: 32
      LastChar: 252
      FontDescriptor: 
       FontName: HelveticaNeue-Bold
       Flags: Symbolic, ForceBold
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
     Font: 
      BaseFont: QBXUTB+PublicoHeadline-Light
      FontSubset: true
      FirstChar: 1
      LastChar: 11
      FontDescriptor: 
       FontName: QBXUTB+PublicoHeadline-Light
       Flags: Nonsymbolic
       FontBBox: -157, -213, 1093, 1026
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: RBSHKS+MyriadPro-SemiboldIt
      FontSubset: true
      FirstChar: 1
      LastChar: 33
      FontDescriptor: 
       FontName: RBSHKS+MyriadPro-SemiboldIt
       Flags: Nonsymbolic, Italic
       FontBBox: -193, -250, 1164, 972
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
    CIDFontType2: 
     Font: 
      BaseFont: TKZZVR+TimesNewRomanPSMT
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: TKZZVR+TimesNewRomanPSMT
       Flags: Nonsymbolic
       FontBBox: -568, -307, 2000, 1007
       FontFile2: true
     Font: 
      BaseFont: LPFFIY+ArialMT
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: LPFFIY+ArialMT
       Flags: Nonsymbolic
       FontBBox: -665, -325, 2000, 1006
       FontFile2: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/">
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="" xmlns:dc="http://purl.org/dc/elements/1.1/"><dc:format>application/pdf</dc:format><dc:identifier>doi:10.1002/chem.202401165</dc:identifier></rdf:Description>
<rdf:Description rdf:about="" xmlns:prism="http://prismstandard.org/namespaces/basic/2.1/"><prism:doi>10.1002/chem.202401165</prism:doi><prism:url>https://doi.org/10.1002/chem.202401165</prism:url></rdf:Description>
<rdf:Description rdf:about="" xmlns:crossmark="http://crossref.org/crossmark/1.0/"><crossmark:MajorVersionDate>2024-06-04</crossmark:MajorVersionDate><crossmark:CrossmarkDomainExclusive>true</crossmark:CrossmarkDomainExclusive><crossmark:CrossMarkDomains><rdf:Seq><rdf:li>chemistry-europe.onlinelibrary.wiley.com</rdf:li></rdf:Seq></crossmark:CrossMarkDomains><crossmark:DOI>10.1002/chem.202401165</crossmark:DOI></rdf:Description>
<rdf:Description rdf:about="" xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/"><pdfx:CrossMarkDomains><rdf:Seq><rdf:li>chemistry-europe.onlinelibrary.wiley.com</rdf:li></rdf:Seq></pdfx:CrossMarkDomains><pdfx:CrossmarkDomainExclusive>true</pdfx:CrossmarkDomainExclusive><pdfx:doi>10.1002/chem.202401165</pdfx:doi><pdfx:CrossmarkMajorVersionDate>2024-06-04</pdfx:CrossmarkMajorVersionDate></rdf:Description>
<rdf:Description rdf:about="" xmlns:jav="http://www.niso.org/schemas/jav/1.0/"><jav:journal_article_version>VoR</jav:journal_article_version></rdf:Description>
</rdf:RDF></x:xmpmeta>
   Pages: 
    Page: 
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 46, 674, 153, 687
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 164, 674, 291, 687
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 326, 674, 409, 687
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 58, 136, 181, 143
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 0, 841, 76, 826
    Page: 
     Sequence: 2
    Page: 
     Sequence: 3
    Page: 
     Sequence: 4
    Page: 
     Sequence: 5
    Page: 
     Sequence: 6
    Page: 
     Sequence: 7
    Page: 
     Sequence: 8
    Page: 
     Sequence: 9
    Page: 
     Sequence: 10
    Page: 
     Sequence: 11
    Page: 
     Sequence: 12
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 144, 266, 222, 274
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 142, 239, 246, 247
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 62, 230, 198, 238
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 93, 194, 196, 202
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 103, 185, 215, 193
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 278, 176, 290, 184
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 62, 167, 162, 175
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 202, 158, 290, 166
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 62, 149, 77, 157
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 199, 140, 290, 148
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 62, 131, 77, 139
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 139, 113, 273, 121
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 214, 104, 290, 112
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 62, 95, 119, 103
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 384, 759, 516, 766
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 486, 750, 548, 757
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 320, 741, 359, 748
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 342, 713, 449, 721
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 515, 668, 548, 675
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 320, 659, 389, 666
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 498, 650, 548, 657
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 320, 641, 388, 648
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 320, 622, 396, 630
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 460, 604, 548, 612
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 320, 595, 331, 603
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 393, 586, 507, 594
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 378, 568, 465, 575
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 447, 550, 546, 557
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 536, 541, 548, 548
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 320, 532, 412, 539
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 320, 513, 417, 521
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 395, 495, 494, 503
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 361, 459, 475, 466
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 423, 322, 529, 330
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 441, 313, 548, 321
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 320, 304, 331, 312
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 381, 304, 491, 312
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 462, 277, 548, 284
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 320, 268, 354, 275
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 509, 259, 548, 266
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 320, 250, 393, 257
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 494, 232, 548, 239
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 320, 222, 381, 230
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 449, 213, 548, 221
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 320, 204, 335, 212
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 399, 195, 510, 203
       Flags: Print
    Page: 
     Sequence: 13
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 102, 741, 243, 748
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 257, 732, 290, 739
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 62, 723, 148, 730
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 62, 705, 165, 712
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 115, 696, 246, 703
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 225, 687, 290, 694
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 62, 678, 115, 685
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 113, 669, 249, 676
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 185, 660, 290, 667
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 62, 651, 74, 658
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 62, 633, 176, 640
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 203, 624, 290, 631
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 62, 615, 89, 622
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 393, 759, 514, 766
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 433, 750, 548, 757
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 320, 741, 331, 748
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 525, 741, 548, 748
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 320, 732, 435, 739
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 503, 687, 548, 694
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 320, 678, 413, 685
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 320, 669, 429, 676
       Flags: Print
    Page: 
     Sequence: 14
  Checksum: f8f72748
   Type: CRC32
  Checksum: 4a691c0cdc481a6ee9e000785bc7a537
   Type: MD5
  Checksum: c36edc8e2c46fedbbb3ce8271dc2af32be3b892e
   Type: SHA-1
  Checksum: 0424adfbf03a228711b89cddba2b19df4c1fe74282b5ee938f50381c2b74175c
   Type: SHA-256