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Title:           Experimental and computational biophysics to identify vasodilator drugs targeted at TRPV2 using agonists based on the probenecid scaffold
Subject:         Computational and Structural Biotechnology Journal, 23 (2024) 473-482. doi:10.1016/j.csbj.2023.12.028
Keywords:        Ion channels,TRP channels,TRPV2,Drug discovery,Membrane proteins,Biophysics,Docking,Cardiovascular,Computational biology,Structural biology,Pharmacology
Author:          Èric Catalina-Hernández
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      Title: Experimental and computational biophysics to identify vasodilator drugs targeted at TRPV2 using agonists based on the probe ...
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        Title: 1 Introduction
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        Title: 2 Results and discussion
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          Title: 2.1 Chemoinformatics similarity search for putative TRPV2 modulators
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          Title: 2.2 Ligand-based virtual screening and PBCD binding site assignment
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          Title: 2.3 Design of a Ca2+ assay to test TRPV2 activity
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          Title: 2.4 EC50 estimation and data analysis
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          Title: 2.5 Agonist-mode determination of PBCD-derivatives activity
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          Title: 2.6 Assessing vascular responses to TRPV2 agonists
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          Title: 2.7 Influence of sex in TRPV2 agonists’ vascular responses   the case of PSBA
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          Title: 2.8 Putative binding site for PSBA
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        Title: 3 Conclusions
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        Title: Material and methods
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    Author: Èric Catalina-Hernández
    Subject: Computational and Structural Biotechnology Journal, 23 (2024) 473-482. doi:10.1016/j.csbj.2023.12.028
    Keywords: Ion channels,TRP channels,TRPV2,Drug discovery,Membrane proteins,Biophysics,Docking,Cardiovascular,Computational biology,Structural biology,Pharmacology
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  Checksum: b45dc9b6bcde821f4e80a1a92eb2900f
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