c5f643a080f8cb4698494e9069a58b51 animals-14-01541.pdf 9484d8728823de46c7a1f53478158070bd545de5 animals-14-01541.pdf b80a33ef65500ac2b1dc339d1d25e400ce2774dca866adbbde9beb31402fccef animals-14-01541.pdf Title: A Standardized Nomenclature Design for Systematic Referencing and Identification of Animal Cellular Material Subject: The documentation, preservation and rescue of biological diversity increasingly uses living biological samples. Persistent associations between species, biosamples, such as tissues and cell lines, and the accompanying data are indispensable for using, exchanging and benefiting from these valuable materials. Explicit authentication of such biosamples by assigning unique and robust identifiers is therefore required to allow for unambiguous referencing, avoid identification conflicts and maintain reproducibility in research. A predefined nomenclature based on uniform rules would facilitate this process. However, such a nomenclature is currently lacking for animal biological material. We here present a first, standardized, human-readable nomenclature design, which is sufficient to generate unique and stable identifying names for animal cellular material with a focus on wildlife species. A species-specific human- and machine-readable syntax is included in the proposed standard naming scheme, allowing for the traceability of donated material and cultured cells, as well as data FAIRification. Only when it is consistently applied in the public domain, as publications and inter-institutional samples and data are exchanged, distributed and stored centrally, can the risks of misidentification and loss of traceability be mitigated. This innovative globally applicable identification system provides a standard for a sustainable structure for the long-term storage of animal bio-samples in cryobanks and hence facilitates current as well as future species conservation and biomedical research. Keywords: viable cell material; wildlife; biosample nomenclature; cryobanking; standardization; unambiguous identifier; FAIR data; biodiversity; species conservation Author: Lisa Schrade, Nancy Mah, Anita Bandrowski, Ying Chen, Johannes Dewender, Sebastian Diecke, Christian Hiepen, Madeline A. Lancaster, Tomas Marques-Bonet, Sira Martinez, Sabine C. Mueller, Christopher Navara, Alessandro Prigione, Stefanie Seltmann, Jaroslaw Sochacki, Magdalena A. Sutcliffe, Vera Zywitza, Thomas B. Hildebrandt and Andreas Kurtz Creator: LaTeX with hyperref Producer: pdfTeX-1.40.25 CreationDate: Thu May 23 11:50:27 2024 CEST ModDate: Thu May 23 11:59:30 2024 CEST Custom Metadata: no Metadata Stream: no Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 12 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 1285975 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MXTWPO+VnURWPalladioL Type 1 Custom yes yes yes 10 0 DWZWEV+URWPalladioL-Bold Type 1 Custom yes yes yes 16 0 UVNLBG+URWPalladioL-Roma Type 1 Custom yes yes yes 22 0 NMOPQA+URWPalladioL-Ital Type 1 Custom yes yes yes 27 0 SZMRXJ+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 43 0 KHIFKD+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 75 0 KHIFKE+PalatinoLinotype CID TrueType Identity-H yes yes yes 78 0 KHIFKF+PalatinoLinotype TrueType WinAnsi yes yes no 84 0 KHIFKH+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 87 0 KHIGCG+PalatinoLinotype TrueType MacRoman yes yes no 90 0 KHIFKD+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 98 0 KHIFKE+PalatinoLinotype CID TrueType Identity-H yes yes yes 101 0 KHIFKF+PalatinoLinotype TrueType WinAnsi yes yes no 107 0 KHIFKH+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 110 0 KHIGCG+PalatinoLinotype TrueType MacRoman yes yes no 113 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-10-03 02:35:46 CEST RepresentationInformation: animals-14-01541.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-09-09 07:04:25 CEST Size: 1285975 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 374 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: section.1 Children: Item: Title: Background Destination: subsection.1.1 Item: Title: Need for a Standardized Nomenclature Design for Animal Biosamples Destination: subsection.1.2 Children: Item: Title: Free-Text Names Have Little or No Interpretability Destination: subsubsection.1.2.1 Item: Title: Scientific Exchange and Cryobanking Destination: subsubsection.1.2.2 Item: Title: Methods Destination: section.2 Children: Item: Title: Requirements of a Standardized Nomenclature Destination: subsection.2.1 Item: Title: Nomenclature Components Destination: subsection.2.2 Item: Title: Results Destination: section.3 Children: Item: Title: Proposed Standardized Nomenclature Defined Formal Pattern Destination: subsection.3.1 Item: Title: Nomenclature Adaptation to Transformation Processes Destination: subsection.3.2 Item: Title: Discussion Destination: section.4 Children: Item: Title: Scheme for a Species Identifier Destination: subsection.4.1 Item: Title: Adaptations and Limitations of the Nomenclature Design Destination: subsection.4.2 Item: Title: Conclusions Destination: section.5 Item: Title: References Destination: appendix.A. Info: Title: A Standardized Nomenclature Design for Systematic Referencing and Identification of Animal Cellular Material Author: Lisa Schrade, Nancy Mah, Anita Bandrowski, Ying Chen, Johannes Dewender, Sebastian Diecke, Christian Hiepen, Madeline A. Lancaster, Tomas Marques-Bonet, Sira Martinez, Sabine C. Mueller, Christopher Navara, Alessandro Prigione, Stefanie Seltmann, Jaroslaw Sochacki, Magdalena A. Sutcliffe, Vera Zywitza, Thomas B. Hildebrandt and Andreas Kurtz Subject: The documentation, preservation and rescue of biological diversity increasingly uses living biological samples. Persistent associations between species, biosamples, such as tissues and cell lines, and the accompanying data are indispensable for using, exchanging and benefiting from these valuable materials. Explicit authentication of such biosamples by assigning unique and robust identifiers is therefore required to allow for unambiguous referencing, avoid identification conflicts and maintain reproducibility in research. A predefined nomenclature based on uniform rules would facilitate this process. However, such a nomenclature is currently lacking for animal biological material. We here present a first, standardized, human-readable nomenclature design, which is sufficient to generate unique and stable identifying names for animal cellular material with a focus on wildlife species. A species-specific human- and machine-readable syntax is included in the proposed standard naming scheme, allowing for the traceability of donated material and cultured cells, as well as data FAIRification. Only when it is consistently applied in the public domain, as publications and inter-institutional samples and data are exchanged, distributed and stored centrally, can the risks of misidentification and loss of traceability be mitigated. This innovative globally applicable identification system provides a standard for a sustainable structure for the long-term storage of animal bio-samples in cryobanks and hence facilitates current as well as future species conservation and biomedical research. 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