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Title:           Implications of noncoding regulatory functions in the development of insulinomas
Subject:         Cell Genomics, 4 (2024) 100604. doi:10.1016/j.xgen.2024.100604
Author:          Mireia Ramos-Rodríguez
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       Item: 
        Title: Results
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         Item: 
          Title: Mapping the regulatory landscape of insulinomas
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         Item: 
          Title: Recurrent coding mutations in insulinoma are rare
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         Item: 
          Title: The impact of noncoding somatic mutations
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         Item: 
          Title: Uncovering tumor-specific regulatory domains
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         Item: 
          Title: IRDs map to polycomb-repressed regions in healthy human islets
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         Item: 
          Title: Limitations of the study
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        Title: Supplemental information
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        Title: STAR★Methods
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          Title: Resource availability
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          Title: Experimental model and study participant details
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            Title: RNA-seq
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           Item: 
            Title: ChIP-seq and Cut&Tag
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            Title: WGS
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            Title: Immunofluorescence and immunohistochemistry stainings
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            Title: RNA-seq
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            Title: ChIP-seq and Cut&Tag
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            Title: Consensus H3K27ac sites
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            Title: Differential analysis of RNA-seq and ChIP-seq
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            Title: Data normalization and transformation
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            Title: Assigning regulatory elements to target genes
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            Title: Sharing and rank indexes
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            Title: Whole-genome sequencing
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            Title: Somatic variant calling and filtering
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            Title: Tumor mutational burden (TMB)
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            Title: Mutational signatures
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            Title: Structural variant calling
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            Title: Variants enrichment analysis
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            Title: Differential H3K27ac enrichment at VREs and nearby gene expression analysis
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            Title: Conservation analysis
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            Title: Oncoplot
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            Title: Pathway enrichment analyses
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           Item: 
            Title: Insulinoma Regulatory Domains
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            Title: Sequence composition and transcription factor analyses
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            Title: Core transcriptional regulatory circuitry
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            Title: Overlap with H3K27me3 regions
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   Type: CRC32
  Checksum: b9285d45057f6cf0dba1db2bbc768161
   Type: MD5
  Checksum: f48be24dd45cec0f15d03a0deda9e4fc0effe49a
   Type: SHA-1
  Checksum: 3a255d3a67b6f0688d6e46b4e213ba5445a9afb6f2414b157ab8026b73d7e6e5
   Type: SHA-256