557537c61d5abaa85f91566a3e8835be  301952.pdf
9baa6d0f8ef941477d9699ae9341cdb46046cea3  301952.pdf
185bb8268601aefc7916cf5b4ee80e66635ec0108d7c7aa9f474b9a055fcd320  301952.pdf

Title:           SIRT7: a novel molecular target for personalized cancer treatment?
Subject:         Oncogene, doi:10.1038/s41388-024-02976-8
Keywords:        
Author:          Alessandro Ianni
Creator:         Springer
CreationDate:    Thu Mar 21 17:10:46 2024 CET
ModDate:         Thu Mar 21 17:11:15 2024 CET
Custom Metadata: no
Metadata Stream: yes
Tagged:          no
UserProperties:  no
Suspects:        no
Form:            AcroForm
JavaScript:      no
Pages:           14
Encrypted:       no
Page size:       595.276 x 790.866 pts
Page rot:        0
File size:       5205770 bytes
Optimized:       yes
PDF version:     1.4


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
DCKHEG+AdvTT5afe5d37.B               Type 1C           WinAnsi          yes yes no     871  0
DCKJLA+AdvOT3b30f6db.B               Type 1C           WinAnsi          yes yes no     891  0
DCKJMB+AdvOT46dcae81+20              Type 1C           WinAnsi          yes yes no     892  0
DCKJMC+AdvOT65f8a23b.I               Type 1C           WinAnsi          yes yes no     900  0
DCKJNC+AdvOTa20b42a7                 Type 1C           WinAnsi          yes yes no     899  0
Arial-BoldMT                         Type 1C           WinAnsi          yes no  no     872  0
DCKICC+AdvOT46dcae81                 Type 1C           WinAnsi          yes yes no     877  0
DCKIDD+AdvTT6780a46b                 Type 1C           WinAnsi          yes yes no     878  0
DCKIHD+AdvTT2876772e+27              Type 1C           Custom           yes yes yes    883  0
DCKJIN+AdvTTab7e17fd                 Type 1C           WinAnsi          yes yes no     884  0
DCKJIO+AdvOT46dcae81+fb              Type 1C           Custom           yes yes yes    885  0
DCKJJO+AdvMyriad_I                   Type 1C           WinAnsi          yes yes no     893  0
DCKJJP+AdvMyriad_R                   Type 1C           WinAnsi          yes yes no     894  0
DCLEDE+AdvOT919a0533.B               Type 1C           WinAnsi          yes yes no     360  0
DCLFKM+AdvOT7d2ebc01                 Type 1C           WinAnsi          yes yes no     365  0
DDAFLB+AdvOT3b30f6db.B+20            Type 1C           WinAnsi          yes yes no     445  0
DDAGDP+AdvOT46dcae81+03              Type 1C           Custom           yes yes yes    477  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2024-11-07 02:44:45 CET
 RepresentationInformation: 301952.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2024-11-06 12:45:41 CET
  Size: 5205770
  Format: PDF
  Version: 1.4
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: Linearized PDF
  PDFMetadata: 
   Objects: 985
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseOutlines
    Outlines: 
     Item: 
      Title: SIRT7: a novel molecular target for personalized cancer treatment?
      Destination: title_link
      Children: 
       Item: 
        Title: Introduction
        Destination: A1
       Item: 
        Title: SIRT7 and the nucleolus: a unique functional interplay with considerable impact on tumorigenesis
        Destination: A2
       Item: 
        Title: SIRT7 is a RNA-binding sirtuin with important roles in RNA synthesis and maturation
        Destination: A3
       Item: 
        Title: SIRT7 possesses unique catalytic activities with potential impacts in cancer progression
        Destination: A4
       Item: 
        Title: The complex contribution of SIRT7 to distinct malignancies
        Destination: A5
        Children: 
         Item: 
          Title: Role of SIRT7 in cancers of the digestive’system
          Destination: B1
         Item: 
          Title: SIRT7 in skin’cancer
          Destination: B2
         Item: 
          Title: SIRT7 in lung’cancer
          Destination: B3
         Item: 
          Title: SIRT7 in thyroid’cancer
          Destination: B4
         Item: 
          Title: SIRT7 in gynecologic malignancies
          Destination: B5
         Item: 
          Title: SIRT7 in prostate’cancer
          Destination: B6
         Item: 
          Title: SIRT7 in bladder’cancer
          Destination: B7
         Item: 
          Title: SIRT7 in sarcoma
          Destination: B8
         Item: 
          Title: Role of SIRT7 in breast’cancer
          Destination: B9
         Item: 
          Title: SIRT7 in head and neck squamous cell carcinoma (HNSCC)
          Destination: B10
         Item: 
          Title: SIRT7 in hematologic malignancies
          Destination: B11
       Item: 
        Title: Conclusions
        Destination: A6
       Item: 
        Title: Acknowledgements
        Destination: A7
       Item: 
        Title: Author contributions
        Destination: A8
       Item: 
        Title: Funding
        Destination: A9
       Item: 
        Title: Competing interests
        Destination: A10
       Item: 
        Title: ADDITIONAL INFORMATION
        Destination: M1
   Info: 
    Title: SIRT7: a novel molecular target for personalized cancer treatment?
    Author: Alessandro Ianni
    Subject: Oncogene, doi:10.1038/s41388-024-02976-8
    Keywords: 
    Creator: Springer
    CreationDate: Thu Mar 21 17:40:46 CET 2024
    ModDate: Thu Mar 21 17:41:15 CET 2024
   ID: 0x1e0f07c85cbb469eb4bc21cb94667f36, 0xe2bff2712a76404998c9d026df0ae730
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 2000
      ImageHeight: 1383
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 2000
      ImageHeight: 1702
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 2000
      ImageHeight: 1569
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 2000
      ImageHeight: 1127
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 2000
      ImageHeight: 1268
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 2000
      ImageHeight: 1377
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 2000
      ImageHeight: 1482
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 2000
      ImageHeight: 1568
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
   Fonts: 
    Type1: 
     Font: 
      BaseFont: DCKJNC+AdvOTa20b42a7
      FontSubset: true
      FirstChar: 48
      LastChar: 121
      FontDescriptor: 
       FontName: DCKJNC+AdvOTa20b42a7
       Flags: Serif, Nonsymbolic
       FontBBox: -72, -239, 979, 906
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DCKJMC+AdvOT65f8a23b.I
      FontSubset: true
      FirstChar: 49
      LastChar: 121
      FontDescriptor: 
       FontName: DCKJMC+AdvOT65f8a23b.I
       Flags: Nonsymbolic
       FontBBox: -104, -250, 885, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DCKHEG+AdvTT5afe5d37.B
      FontSubset: true
      FirstChar: 65
      LastChar: 87
      FontDescriptor: 
       FontName: DCKHEG+AdvTT5afe5d37.B
       Flags: Nonsymbolic
       FontBBox: -31, -250, 895, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: Arial-BoldMT
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: Arial-BoldMT
       Flags: Nonsymbolic
       FontBBox: -628, -376, 2000, 1010
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DCLEDE+AdvOT919a0533.B
      FontSubset: true
      FirstChar: 46
      LastChar: 108
      FontDescriptor: 
       FontName: DCLEDE+AdvOT919a0533.B
       Flags: Nonsymbolic
       FontBBox: -31, -250, 656, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DCKICC+AdvOT46dcae81
      FontSubset: true
      FirstChar: 35
      LastChar: 237
      FontDescriptor: 
       FontName: DCKICC+AdvOT46dcae81
       Flags: Nonsymbolic
       FontBBox: -41, -250, 833, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DCLFKM+AdvOT7d2ebc01
      FontSubset: true
      FirstChar: 48
      LastChar: 57
      FontDescriptor: 
       FontName: DCLFKM+AdvOT7d2ebc01
       Flags: Nonsymbolic
       FontBBox: -31, -208, 958, 916
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DCKIDD+AdvTT6780a46b
      FontSubset: true
      FirstChar: 40
      LastChar: 122
      FontDescriptor: 
       FontName: DCKIDD+AdvTT6780a46b
       Flags: Nonsymbolic
       FontBBox: -41, -250, 875, 843
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DCKIHD+AdvTT2876772e+27
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: DCKIHD+AdvTT2876772e+27
       Flags: Symbolic
       FontBBox: 0, -197, 968, 770
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: DCKJIN+AdvTTab7e17fd
      FontSubset: true
      FirstChar: 43
      LastChar: 43
      FontDescriptor: 
       FontName: DCKJIN+AdvTTab7e17fd
       Flags: Nonsymbolic
       FontBBox: -156, -250, 1072, 947
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DCKJIO+AdvOT46dcae81+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 3
      FontDescriptor: 
       FontName: DCKJIO+AdvOT46dcae81+fb
       Flags: Symbolic
       FontBBox: 0, 0, 739, 718
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: DCKJLA+AdvOT3b30f6db.B
      FontSubset: true
      FirstChar: 40
      LastChar: 121
      FontDescriptor: 
       FontName: DCKJLA+AdvOT3b30f6db.B
       Flags: Nonsymbolic
       FontBBox: -31, -250, 875, 895
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DCKJMB+AdvOT46dcae81+20
      FontSubset: true
      FirstChar: 146
      LastChar: 150
      FontDescriptor: 
       FontName: DCKJMB+AdvOT46dcae81+20
       Flags: Nonsymbolic
       FontBBox: 0, -197, 1125, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DCKJJO+AdvMyriad_I
      FontSubset: true
      FirstChar: 79
      LastChar: 111
      FontDescriptor: 
       FontName: DCKJJO+AdvMyriad_I
       Flags: Nonsymbolic
       FontBBox: -104, -239, 1083, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DDAFLB+AdvOT3b30f6db.B+20
      FontSubset: true
      FirstChar: 146
      LastChar: 150
      FontDescriptor: 
       FontName: DDAFLB+AdvOT3b30f6db.B+20
       Flags: Nonsymbolic
       FontBBox: -10, -197, 1250, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: DDAGDP+AdvOT46dcae81+03
      FontSubset: true
      FirstChar: 1
      LastChar: 4
      FontDescriptor: 
       FontName: DDAGDP+AdvOT46dcae81+03
       Flags: Symbolic
       FontBBox: -31, -208, 739, 802
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: DCKJJP+AdvMyriad_R
      FontSubset: true
      FirstChar: 40
      LastChar: 150
      FontDescriptor: 
       FontName: DCKJJP+AdvMyriad_R
       Flags: Nonsymbolic
       FontBBox: -41, -239, 1125, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 5.2-c001 63.143651, 2012/04/05-09:01:49        ">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:format>application/pdf</dc:format>
         <dc:identifier>doi:10.1038/s41388-024-02976-8</dc:identifier>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">SIRT7: a novel molecular target for personalized cancer treatment?</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Alessandro Ianni</rdf:li>
               <rdf:li>Poonam Kumari</rdf:li>
               <rdf:li>Shahriar Tarighi</rdf:li>
               <rdf:li>Thomas Braun</rdf:li>
               <rdf:li>Alejandro Vaquero</rdf:li>
            </rdf:Seq>
         </dc:creator>
         <dc:publisher>
            <rdf:Bag>
               <rdf:li>Springer US</rdf:li>
            </rdf:Bag>
         </dc:publisher>
         <dc:subject>
            <rdf:Bag/>
         </dc:subject>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Oncogene, doi:10.1038/s41388-024-02976-8</rdf:li>
            </rdf:Alt>
         </dc:description>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmp="http://ns.adobe.com/xap/1.0/">
         <xmp:CreatorTool>Springer</xmp:CreatorTool>
         <xmp:ModifyDate>2024-03-21T21:41:15+05:30</xmp:ModifyDate>
         <xmp:CreateDate>2024-03-21T21:40:46+05:30</xmp:CreateDate>
         <xmp:MetadataDate>2024-03-21T21:41:15+05:30</xmp:MetadataDate>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpRights="http://ns.adobe.com/xap/1.0/rights/">
         <xmpRights:Marked>True</xmpRights:Marked>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:Keywords/>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/"
            xmlns:stEvt="http://ns.adobe.com/xap/1.0/sType/ResourceEvent#">
         <xmpMM:DocumentID>uuid:ef8b08f5-efe0-4513-b2b3-47010bdec305</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:9ce588e0-aa66-4170-9549-2327412d95b5</xmpMM:InstanceID>
         <xmpMM:RenditionClass>default</xmpMM:RenditionClass>
         <xmpMM:VersionID>1</xmpMM:VersionID>
         <xmpMM:History>
            <rdf:Seq>
               <rdf:li rdf:parseType="Resource">
                  <stEvt:action>converted</stEvt:action>
                  <stEvt:instanceID>uuid:4aa5a6c3-96c6-443e-9322-842e405f1a86</stEvt:instanceID>
                  <stEvt:parameters>converted to PDF/A-2b</stEvt:parameters>
                  <stEvt:softwareAgent>pdfToolbox</stEvt:softwareAgent>
                  <stEvt:when>2024-03-21T21:41:15+05:30</stEvt:when>
               </rdf:li>
            </rdf:Seq>
         </xmpMM:History>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdfaid="http://www.aiim.org/pdfa/ns/id/">
         <pdfaid:part>2</pdfaid:part>
         <pdfaid:conformance>B</pdfaid:conformance>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdfaExtension="http://www.aiim.org/pdfa/ns/extension/"
            xmlns:pdfaSchema="http://www.aiim.org/pdfa/ns/schema#"
            xmlns:pdfaProperty="http://www.aiim.org/pdfa/ns/property#">
         <pdfaExtension:schemas>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/pdf/1.3/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdf</pdfaSchema:prefix>
                  <pdfaSchema:schema>Adobe PDF Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>A name object indicating whether the document has been modified to include trapping information</pdfaProperty:description>
                           <pdfaProperty:name>Trapped</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/pdfx/1.3/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdfx</pdfaSchema:prefix>
                  <pdfaSchema:schema>Adobe Document Info PDF eXtension Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>ID of PDF/X standard</pdfaProperty:description>
                           <pdfaProperty:name>GTS_PDFXVersion</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Conformance level of PDF/X standard</pdfaProperty:description>
                           <pdfaProperty:name>GTS_PDFXConformance</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Company creating the PDF</pdfaProperty:description>
                           <pdfaProperty:name>Company</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Date when document was last modified</pdfaProperty:description>
                           <pdfaProperty:name>SourceModified</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/xap/1.0/mm/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>xmpMM</pdfaSchema:prefix>
                  <pdfaSchema:schema>XMP Media Management Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>UUID based identifier for specific incarnation of a document</pdfaProperty:description>
                           <pdfaProperty:name>InstanceID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>The common identifier for all versions and renditions of a document.</pdfaProperty:description>
                           <pdfaProperty:name>OriginalDocumentID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://www.aiim.org/pdfa/ns/id/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdfaid</pdfaSchema:prefix>
                  <pdfaSchema:schema>PDF/A ID Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Part of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>part</pdfaProperty:name>
                           <pdfaProperty:valueType>Integer</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Amendment of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>amd</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Conformance level of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>conformance</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
            </rdf:Bag>
         </pdfaExtension:schemas>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 993
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 478, 689, 480, 721
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 478, 695, 534, 727
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 534, 695, 549, 705
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 534, 695, 549, 705
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 100, 628, 101, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 100, 628, 101, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 110, 628, 112, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 102, 628, 110, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 110, 628, 110, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 262, 628, 263, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 262, 628, 263, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 272, 628, 274, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 264, 628, 272, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 272, 628, 272, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 336, 628, 337, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 336, 628, 337, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 346, 628, 349, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 339, 628, 346, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 346, 628, 346, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 443, 628, 444, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 443, 628, 444, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 453, 628, 456, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 446, 628, 453, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 453, 628, 453, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 166, 452, 331, 461
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 65, 354, 70, 363
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 74, 354, 79, 363
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 111, 324, 115, 333
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 120, 324, 124, 333
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 266, 294, 270, 303
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 275, 294, 279, 303
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 196, 215, 200, 224
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 131, 195, 135, 204
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 206, 155, 211, 164
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 179, 125, 184, 134
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 485, 334, 490, 343
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 494, 334, 504, 343
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 535, 334, 540, 343
       Flags: Print
       AppearanceDictionary: true
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 408, 284, 418, 293
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 422, 284, 431, 293
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 491, 225, 500, 234
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 504, 225, 513, 234
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 535, 225, 540, 234
       Flags: Print
       AppearanceDictionary: true
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 60, 80, 157, 87
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 161, 80, 252, 87
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 474, 749, 549, 757
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Label: 994
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 92, 278, 97, 287
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 101, 278, 110, 287
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 47, 179, 52, 188
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 57, 179, 66, 188
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 72, 139, 77, 148
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 132, 129, 141, 138
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 279, 109, 289, 118
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 246, 69, 255, 78
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 262, 69, 271, 78
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 225, 59, 234, 68
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 313, 308, 322, 317
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 340, 269, 350, 278
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 313, 249, 322, 258
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 366, 229, 371, 238
       Flags: Print
       AppearanceDictionary: true
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 511, 199, 520, 208
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 517, 179, 526, 188
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 532, 179, 541, 188
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 545, 179, 555, 188
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
     Thumb: true
    Page: 
     Label: 995
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 270, 703, 279, 712
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 153, 633, 162, 642
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 108, 573, 112, 582
       Flags: Print
       AppearanceDictionary: true
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 126, 573, 131, 582
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 137, 573, 146, 582
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 275, 563, 279, 572
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 108, 414, 112, 423
       Flags: Print
       AppearanceDictionary: true
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 66, 384, 75, 393
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 174, 364, 183, 373
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 177, 334, 186, 343
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 199, 225, 208, 234
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 205, 205, 214, 214
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 38, 145, 47, 154
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 270, 85, 279, 94
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 173, 65, 182, 74
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 366, 583, 375, 592
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 304, 524, 313, 533
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 318, 524, 327, 533
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 331, 524, 341, 533
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 385, 494, 390, 503
       Flags: Print
       AppearanceDictionary: true
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 403, 494, 412, 503
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 416, 494, 426, 503
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 361, 404, 370, 413
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 430, 344, 439, 353
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 445, 344, 455, 353
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 461, 344, 470, 353
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 509, 334, 518, 343
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 522, 334, 532, 343
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 536, 334, 545, 343
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 520, 304, 530, 313
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 536, 304, 545, 313
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 483, 284, 492, 293
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 415, 255, 424, 264
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 536, 235, 545, 244
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 466, 215, 470, 224
       Flags: Print
       AppearanceDictionary: true
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 359, 175, 368, 184
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 536, 145, 545, 154
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 411, 95, 420, 104
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
     Thumb: true
    Page: 
     Label: 996
     Sequence: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 218, 268, 223, 277
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 114, 208, 119, 217
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 121, 168, 130, 177
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 272, 138, 277, 147
       Flags: Print
       AppearanceDictionary: true
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 313, 228, 322, 237
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 327, 228, 336, 237
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 462, 198, 471, 207
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 518, 198, 527, 207
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 341, 188, 350, 197
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 354, 188, 363, 197
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 456, 188, 465, 197
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 421, 128, 430, 137
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 435, 128, 444, 137
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 449, 128, 458, 137
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 358, 78, 368, 87
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 377, 78, 386, 87
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 395, 78, 404, 87
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 442, 68, 451, 77
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
     Thumb: true
    Page: 
     Label: 997
     Sequence: 5
     Thumb: true
    Page: 
     Label: 998
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 164, 290, 173, 299
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 66, 251, 70, 259
       Flags: Print
       AppearanceDictionary: true
       Destination: 72
      Annotation: 
       Subtype: Link
       Rect: 127, 251, 131, 259
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 142, 251, 151, 259
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 45, 191, 49, 200
       Flags: Print
       AppearanceDictionary: true
       Destination: 72
      Annotation: 
       Subtype: Link
       Rect: 97, 191, 101, 200
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 109, 191, 118, 200
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 146, 131, 151, 140
       Flags: Print
       AppearanceDictionary: true
       Destination: 72
      Annotation: 
       Subtype: Link
       Rect: 200, 131, 205, 140
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 213, 131, 222, 140
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 141, 91, 146, 100
       Flags: Print
       AppearanceDictionary: true
       Destination: 72
      Annotation: 
       Subtype: Link
       Rect: 199, 91, 204, 100
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 213, 91, 222, 100
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 463, 300, 472, 309
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 360, 221, 369, 230
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 377, 91, 381, 100
       Flags: Print
       AppearanceDictionary: true
       Destination: 72
      Annotation: 
       Subtype: Link
       Rect: 430, 91, 435, 100
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 491, 61, 500, 70
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
     Thumb: true
    Page: 
     Label: 999
     Sequence: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 72, 693, 76, 702
       Flags: Print
       AppearanceDictionary: true
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 125, 693, 130, 702
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 138, 693, 147, 702
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 122, 663, 126, 672
       Flags: Print
       AppearanceDictionary: true
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 173, 663, 177, 672
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 185, 663, 194, 672
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 107, 643, 116, 652
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 55, 563, 60, 572
       Flags: Print
       AppearanceDictionary: true
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 113, 563, 118, 572
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 127, 563, 136, 572
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 118, 504, 123, 513
       Flags: Print
       AppearanceDictionary: true
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 176, 504, 181, 513
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 190, 504, 199, 513
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 80, 474, 89, 483
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 38, 454, 47, 463
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 93, 354, 102, 363
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 523, 673, 528, 682
       Flags: Print
       AppearanceDictionary: true
       Destination: 109
      Annotation: 
       Subtype: Link
       Rect: 325, 663, 329, 672
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 337, 663, 346, 672
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 448, 593, 458, 602
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 346, 554, 356, 562
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 363, 554, 372, 562
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 487, 544, 496, 552
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 500, 504, 509, 513
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 363, 354, 368, 363
       Flags: Print
       AppearanceDictionary: true
       Destination: 135
      Annotation: 
       Subtype: Link
       Rect: 417, 354, 422, 363
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
     Thumb: true
    Page: 
     Label: 1000
     Sequence: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 90, 372, 99, 381
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 224, 342, 233, 351
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 47, 322, 56, 331
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 283, 262, 288, 271
       Flags: Print
       AppearanceDictionary: true
       Destination: 135
      Annotation: 
       Subtype: Link
       Rect: 89, 252, 93, 261
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 103, 252, 112, 261
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 214, 202, 223, 211
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 192, 152, 201, 161
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 209, 152, 219, 161
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 105, 113, 110, 122
       Flags: Print
       AppearanceDictionary: true
       Destination: 169
      Annotation: 
       Subtype: Link
       Rect: 173, 113, 177, 122
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 187, 113, 196, 122
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 510, 392, 515, 400
       Flags: Print
       AppearanceDictionary: true
       Destination: 169
      Annotation: 
       Subtype: Link
       Rect: 311, 382, 315, 391
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 325, 382, 334, 391
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 357, 372, 366, 381
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 386, 332, 390, 341
       Flags: Print
       AppearanceDictionary: true
       Destination: 169
      Annotation: 
       Subtype: Link
       Rect: 440, 332, 444, 341
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 452, 332, 461, 341
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 379, 312, 388, 321
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 418, 212, 423, 221
       Flags: Print
       AppearanceDictionary: true
       Destination: 209
      Annotation: 
       Subtype: Link
       Rect: 471, 212, 476, 221
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 484, 212, 493, 221
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 381, 152, 390, 161
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 400, 152, 409, 161
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 359, 123, 368, 131
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 374, 123, 383, 131
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 539, 103, 544, 112
       Flags: Print
       AppearanceDictionary: true
       Destination: 209
      Annotation: 
       Subtype: Link
       Rect: 356, 93, 361, 102
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 371, 93, 380, 102
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 387, 93, 396, 102
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 349, 63, 358, 72
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
     Thumb: true
    Page: 
     Label: 1001
     Sequence: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 222, 312, 226, 321
       Flags: Print
       AppearanceDictionary: true
       Destination: 209
      Annotation: 
       Subtype: Link
       Rect: 276, 312, 281, 321
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 38, 302, 47, 311
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 124, 212, 133, 222
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 138, 212, 147, 222
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 254, 193, 263, 202
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 270, 193, 279, 202
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 216, 173, 225, 182
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 234, 173, 244, 182
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 130, 133, 135, 142
       Flags: Print
       AppearanceDictionary: true
       Destination: 209
      Annotation: 
       Subtype: Link
       Rect: 186, 133, 190, 142
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 199, 133, 208, 142
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 272, 73, 281, 82
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 54, 63, 59, 72
       Flags: Print
       AppearanceDictionary: true
       Destination: 209
      Annotation: 
       Subtype: Link
       Rect: 106, 63, 111, 72
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 469, 322, 479, 331
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 475, 292, 484, 301
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 489, 292, 499, 301
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 519, 252, 528, 261
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 536, 252, 545, 261
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 304, 212, 313, 222
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 318, 212, 327, 222
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 353, 212, 357, 222
       Flags: Print
       AppearanceDictionary: true
       Destination: 247
      Annotation: 
       Subtype: Link
       Rect: 408, 212, 412, 222
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 521, 123, 526, 132
       Flags: Print
       AppearanceDictionary: true
       Destination: 247
      Annotation: 
       Subtype: Link
       Rect: 329, 113, 333, 122
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 346, 113, 355, 122
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 539, 83, 544, 92
       Flags: Print
       AppearanceDictionary: true
       Destination: 247
      Annotation: 
       Subtype: Link
       Rect: 341, 73, 346, 82
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 354, 73, 363, 82
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
     Thumb: true
    Page: 
     Label: 1002
     Sequence: 10
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 194, 302, 203, 311
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 162, 233, 171, 242
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 263, 203, 273, 212
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 45, 193, 49, 202
       Flags: Print
       AppearanceDictionary: true
       Destination: 247
      Annotation: 
       Subtype: Link
       Rect: 96, 193, 101, 202
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 85, 163, 90, 172
       Flags: Print
       AppearanceDictionary: true
       Destination: 247
      Annotation: 
       Subtype: Link
       Rect: 138, 163, 143, 172
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 151, 163, 160, 172
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 209, 123, 218, 132
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 125, 93, 134, 102
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 101, 73, 106, 82
       Flags: Print
       AppearanceDictionary: true
       Destination: 247
      Annotation: 
       Subtype: Link
       Rect: 155, 73, 160, 82
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 168, 73, 177, 82
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 336, 282, 345, 291
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 516, 273, 524, 281
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 529, 273, 538, 281
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 311, 193, 315, 202
       Flags: Print
       AppearanceDictionary: true
       Destination: 277
      Annotation: 
       Subtype: Link
       Rect: 367, 193, 371, 202
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 380, 193, 389, 202
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 395, 193, 404, 202
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 546, 173, 555, 182
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 313, 93, 322, 102
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
     Thumb: true
    Page: 
     Label: 1003
     Sequence: 11
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 146, 300, 151, 309
       Flags: Print
       AppearanceDictionary: true
       Destination: 277
      Annotation: 
       Subtype: Link
       Rect: 198, 300, 202, 309
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 210, 300, 219, 309
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 223, 300, 232, 309
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 159, 270, 168, 279
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 210, 260, 219, 269
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 225, 260, 234, 269
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 153, 240, 162, 249
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 220, 190, 229, 199
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 58, 130, 63, 139
       Flags: Print
       AppearanceDictionary: true
       Destination: 277
      Annotation: 
       Subtype: Link
       Rect: 124, 130, 129, 139
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 141, 130, 150, 139
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 66, 110, 75, 119
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 76, 80, 85, 89
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 522, 220, 527, 229
       Flags: Print
       AppearanceDictionary: true
       Destination: 277
      Annotation: 
       Subtype: Link
       Rect: 325, 210, 330, 219
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 338, 210, 347, 219
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 524, 110, 529, 119
       Flags: Print
       AppearanceDictionary: true
       Destination: 277
      Annotation: 
       Subtype: Link
       Rect: 324, 100, 329, 109
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 336, 100, 345, 109
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
     Thumb: true
    Page: 
     Label: 1004
     Sequence: 12
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 78, 693, 87, 702
       Flags: Print
       AppearanceDictionary: true
       Destination: 322
      Annotation: 
       Subtype: Link
       Rect: 92, 693, 101, 702
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 137, 633, 142, 642
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 257, 573, 261, 582
       Flags: Print
       AppearanceDictionary: true
       Destination: 305
      Annotation: 
       Subtype: Link
       Rect: 148, 504, 157, 513
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 90, 464, 99, 473
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 209, 444, 214, 453
       Flags: Print
       AppearanceDictionary: true
       Destination: 277
      Annotation: 
       Subtype: Link
       Rect: 261, 444, 266, 453
       Flags: Print
       AppearanceDictionary: true
       Destination: 98
      Annotation: 
       Subtype: Link
       Rect: 274, 444, 283, 453
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
      Annotation: 
       Subtype: Link
       Rect: 117, 314, 126, 323
       Flags: Print
       AppearanceDictionary: true
       Destination: 329
     Thumb: true
    Page: 
     Label: 1005
     Sequence: 13
     Thumb: true
    Page: 
     Label: 1006
     Sequence: 14
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 338, 640, 418, 647
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 488, 413, 559, 419
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 311, 404, 333, 411
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 541, 251, 559, 258
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 311, 242, 422, 249
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
  Checksum: 2c4f0a09
   Type: CRC32
  Checksum: 557537c61d5abaa85f91566a3e8835be
   Type: MD5
  Checksum: 9baa6d0f8ef941477d9699ae9341cdb46046cea3
   Type: SHA-1
  Checksum: 185bb8268601aefc7916cf5b4ee80e66635ec0108d7c7aa9f474b9a055fcd320
   Type: SHA-256