9abadb1c22c1b14fa4f519bf1166c82c 301969.pdf 53f7fde850799c6eae44e735aac4b5bd6e16134a 301969.pdf f6a60753529b4c92106770b5c74812e3eed1b07836fa3d87658c351f1faf6b53 301969.pdf Title: Cold exposure modulates potential brown adipokines in humans, but only FGF21 is associated with brown adipose tissue volume Subject: Obesity 2024.32:560-570 Creator: Arbortext Advanced Print Publisher 9.1.520/W Unicode Producer: Acrobat Distiller 11.0 (Windows); modified using iText 4.2.0 by 1T3XT CreationDate: Thu Feb 22 07:11:32 2024 CET ModDate: Mon Dec 16 14:34:57 2024 CET Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 2428072 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- DCKHJJ+AdvTTa9c1b374+20 Type 1C Custom yes yes yes 47 0 DCJJOH+AdvTT6071803a.B Type 1C WinAnsi yes yes no 48 0 DCKACC+AdvTTa9c1b374 Type 1C WinAnsi yes yes no 49 0 DCKADD+AdvP4C4E59 Type 1C Custom yes yes yes 103 0 DCKAED+AdvOT8608a8d1+03 Type 1C Custom yes yes yes 123 0 DCKAEE+AdvTTeb5f0e55.I Type 1C WinAnsi yes yes no 104 0 DCKAFF+AdvP4C4E74 Type 1C Custom yes yes yes 83 0 Times-Roman Type 1 WinAnsi no no no 5 0 DCKKEK+AdvOT8608a8d1+20 Type 1C WinAnsi yes yes no 81 0 DCNPNC+AdvTTfac587ca.B Type 1C WinAnsi yes yes no 82 0 DCODJM+AdvTTa9c1b374+03 Type 1C Custom yes yes yes 102 0 DCOHDH+AdvP4C4E51 Type 1C WinAnsi yes yes no 122 0 DDAKEA+AdvOT8b40f9c2.B+03 Type 1C Custom yes yes yes 198 0 DDAKEB+AdvTT9c438aa4.BI Type 1C WinAnsi yes yes no 199 0 DDAPCE+AdvOT582d4acf Type 1C WinAnsi yes yes no 313 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-12-19 02:51:51 CET RepresentationInformation: 301969.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-12-18 09:13:15 CET Size: 2428072 Format: PDF Version: 1.7 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ErrorMessage: Invalid indirect destination - referenced object 'crlink_OBY_23970_oby23970-aff-0002' cannot be found ID: PDF-HUL-149 ErrorMessage: Invalid indirect destination - referenced object 'crlink_OBY_23970_oby23970-aff-0003' cannot be found ID: PDF-HUL-149 ErrorMessage: Invalid indirect destination - referenced object 'crlink_OBY_23970_oby23970-aff-0006' cannot be found ID: PDF-HUL-149 ErrorMessage: Invalid indirect destination - referenced object 'crlink_OBY_23970_oby23970-aff-0004' cannot be found ID: PDF-HUL-149 ErrorMessage: Invalid indirect destination - referenced object 'crlink_OBY_23970_oby23970-aff-0001' cannot be found ID: PDF-HUL-149 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'crlink_OBY_23970_oby23970-aff-0004' cannot be found ID: PDF-HUL-122 Offset: 2399341 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'crlink_OBY_23970_oby23970-aff-0006' cannot be found ID: PDF-HUL-122 Offset: 2399341 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'crlink_OBY_23970_oby23970-aff-0001' cannot be found ID: PDF-HUL-122 Offset: 2399341 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'crlink_OBY_23970_oby23970-aff-0003' cannot be found ID: PDF-HUL-122 Offset: 2399341 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'crlink_OBY_23970_oby23970-aff-0002' cannot be found ID: PDF-HUL-122 Offset: 2399341 MIMEtype: application/pdf PDFMetadata: Objects: 0 FreeObjects: 2 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Cold exposure modulates potential brown adipokines in humans, but only FGF21 is associated with brown adipose tissue volume Destination: atl_OBY_23970_ Children: Item: Title: INTRODUCTION Destination: HeadingOBY_23970oby23970-sec-0010 Item: Title: METHODS Destination: HeadingOBY_23970oby23970-sec-0011 Children: Item: Title: Study design Destination: HeadingOBY_23970oby23970-sec-0012 Item: Title: What is already known? Destination: HeadingOBY_23970oby23970-sec-0007 Item: Title: What does this study add? Destination: HeadingOBY_23970oby23970-sec-0008 Item: Title: How might these results change the direction of research or the focus of clinical practice? Destination: HeadingOBY_23970oby23970-sec-0009 Children: Item: Title: Shivering threshold test Destination: HeadingOBY_23970oby23970-sec-0013 Item: Title: Personalized cooling protocol Destination: HeadingOBY_23970oby23970-sec-0014 Item: Title: PET-CT analysis Destination: HeadingOBY_23970oby23970-sec-0015 Item: Title: Plasma levels of batokines Destination: HeadingOBY_23970oby23970-sec-0016 Item: Title: Body composition Destination: HeadingOBY_23970oby23970-sec-0017 Item: Title: Cardiometabolic risk factors Destination: HeadingOBY_23970oby23970-sec-0018 Item: Title: Statistical analyses Destination: HeadingOBY_23970oby23970-sec-0019 Item: Title: RESULTS Destination: HeadingOBY_23970oby23970-sec-0020 Children: Item: Title: Cold exposure modulates plasma levels of batokines in young human adults Destination: HeadingOBY_23970oby23970-sec-0021 Item: Title: The cold-induced change in FGF21 levels, but not the other batokines, is associated with BAT volume Destination: HeadingOBY_23970oby23970-sec-0022 Item: Title: Associations of plasma levels of batokines with body composition and cardiometabolic risk factors Destination: HeadingOBY_23970oby23970-sec-0023 Item: Title: DISCUSSION Destination: HeadingOBY_23970oby23970-sec-0024 Item: Title: ACKNOWLEDGMENTS Destination: HeadingOBY_23970oby23970-sec-0025 Item: Title: FUNDING INFORMATION Destination: HeadingOBY_23970oby23970-sec-0026 Item: Title: CONFLICT OF INTEREST STATEMENT Destination: HeadingOBY_23970oby23970-sec-0027 Item: Title: REFERENCES Destination: HeadingOBY_23970oby23970-bibl-00011 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 228 ImageHeight: 45 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 228 ImageHeight: 45 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1655 ImageHeight: 819 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1897 ImageHeight: 1322 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2073 ImageHeight: 1634 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: DCODJM+AdvTTa9c1b374+03 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: DCODJM+AdvTTa9c1b374+03 Flags: Symbolic FontBBox: -500, -260, 1041, 947 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: DDAKEA+AdvOT8b40f9c2.B+03 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: DDAKEA+AdvOT8b40f9c2.B+03 Flags: Symbolic FontBBox: -500, -416, 916, 937 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: DCKADD+AdvP4C4E59 FontSubset: true FirstChar: 1 LastChar: 61 FontDescriptor: FontName: DCKADD+AdvP4C4E59 Flags: Symbolic FontBBox: -31, -250, 1000, 750 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: DDAKEB+AdvTT9c438aa4.BI FontSubset: true FirstChar: 82 LastChar: 112 FontDescriptor: FontName: DDAKEB+AdvTT9c438aa4.BI Flags: Nonsymbolic FontBBox: -83, -177, 1010, 947 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DCKAEE+AdvTTeb5f0e55.I FontSubset: true FirstChar: 40 LastChar: 233 FontDescriptor: FontName: DCKAEE+AdvTTeb5f0e55.I Flags: Nonsymbolic FontBBox: -83, -177, 989, 927 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DCKHJJ+AdvTTa9c1b374+20 FontSubset: true FirstChar: 2 LastChar: 151 FontDescriptor: FontName: DCKHJJ+AdvTTa9c1b374+20 Flags: Symbolic FontBBox: -239, -218, 1166, 937 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: DCJJOH+AdvTT6071803a.B FontSubset: true FirstChar: 40 LastChar: 233 FontDescriptor: FontName: DCJJOH+AdvTT6071803a.B Flags: Nonsymbolic FontBBox: -52, -177, 1041, 947 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DCKACC+AdvTTa9c1b374 FontSubset: true FirstChar: 37 LastChar: 253 FontDescriptor: FontName: DCKACC+AdvTTa9c1b374 Flags: Nonsymbolic FontBBox: -41, -177, 1010, 927 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DCKKEK+AdvOT8608a8d1+20 FontSubset: true FirstChar: 147 LastChar: 148 FontDescriptor: FontName: DCKKEK+AdvOT8608a8d1+20 Flags: Nonsymbolic FontBBox: -968, -333, 2000, 1020 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DCNPNC+AdvTTfac587ca.B FontSubset: true FirstChar: 49 LastChar: 85 FontDescriptor: FontName: DCNPNC+AdvTTfac587ca.B Flags: Nonsymbolic FontBBox: -72, -177, 1062, 958 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DCKAFF+AdvP4C4E74 FontSubset: true FirstChar: 1 LastChar: 254 FontDescriptor: FontName: DCKAFF+AdvP4C4E74 Flags: Symbolic FontBBox: -20, -958, 1114, 770 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: DDAPCE+AdvOT582d4acf FontSubset: true FirstChar: 180 LastChar: 180 FontDescriptor: FontName: DDAPCE+AdvOT582d4acf Flags: Nonsymbolic FontBBox: -72, -208, 927, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DCOHDH+AdvP4C4E51 FontSubset: true FirstChar: 58 LastChar: 58 FontDescriptor: FontName: DCOHDH+AdvP4C4E51 Flags: Nonsymbolic FontBBox: -31, -239, 1041, 750 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DCKAED+AdvOT8608a8d1+03 FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: DCKAED+AdvOT8608a8d1+03 Flags: Symbolic FontBBox: -479, -364, 854, 927 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true XMP: application/pdfdoi:10.1002/oby.23970 10.1002/oby.23970https://doi.org/10.1002/oby.23970 2024-01-22trueonlinelibrary.wiley.com10.1002/oby.23970 onlinelibrary.wiley.comtrue10.1002/oby.239702024-01-22 VoR Pages: Page: Label: 560 Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 184, 570, 185, 582 Destination: null Annotation: Subtype: Link Rect: 184, 575, 212, 587 Destination: null Annotation: Subtype: Link Rect: 366, 570, 367, 582 Destination: null Annotation: Subtype: Link Rect: 366, 575, 394, 587 Destination: null Annotation: Subtype: Link Rect: 396, 574, 405, 582 Annotation: Subtype: Link Rect: 120, 552, 122, 564 Destination: null Annotation: Subtype: Link Rect: 120, 557, 134, 569 Destination: null Annotation: Subtype: Link Rect: 136, 556, 145, 564 Annotation: Subtype: Link Rect: 308, 552, 309, 564 Destination: null Annotation: Subtype: Link Rect: 308, 557, 321, 569 Destination: null Annotation: Subtype: Link Rect: 324, 556, 332, 564 Annotation: Subtype: Link Rect: 159, 534, 161, 546 Destination: null Annotation: Subtype: Link Rect: 159, 539, 200, 551 Destination: null Annotation: Subtype: Link Rect: 202, 538, 211, 546 Annotation: Subtype: Link Rect: 308, 534, 310, 546 Destination: null Annotation: Subtype: Link Rect: 308, 539, 322, 551 Destination: null Annotation: Subtype: Link Rect: 475, 534, 476, 546 Destination: null Annotation: Subtype: Link Rect: 475, 539, 493, 551 Destination: null Annotation: Subtype: Link Rect: 496, 538, 504, 546 Annotation: Subtype: Link Rect: 146, 516, 147, 528 Destination: null Annotation: Subtype: Link Rect: 146, 521, 160, 533 Destination: null Annotation: Subtype: Link Rect: 268, 516, 269, 528 Destination: null Annotation: Subtype: Link Rect: 268, 521, 289, 533 Destination: null Annotation: Subtype: Link Rect: 291, 520, 300, 528 Annotation: Subtype: Link Rect: 474, 516, 475, 528 Destination: null Annotation: Subtype: Link Rect: 474, 521, 519, 533 Destination: null Annotation: Subtype: Link Rect: 522, 520, 530, 528 Annotation: Subtype: Link Rect: 65, 433, 102, 440 Annotation: Subtype: Link Rect: 45, 423, 121, 430 Annotation: Subtype: Link Rect: 205, 64, 350, 71 Annotation: Subtype: Link Rect: 73, 25, 146, 32 Annotation: Subtype: Link Rect: 519, 782, 595, 767 Thumb: true Page: Label: 561 Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 279, 675, 284, 683 Destination: 255 Annotation: Subtype: Link Rect: 67, 636, 71, 644 Destination: 255 Annotation: Subtype: Link Rect: 114, 610, 119, 618 Destination: 255 Annotation: Subtype: Link Rect: 120, 584, 124, 592 Destination: 255 Annotation: Subtype: Link Rect: 196, 519, 201, 527 Destination: 255 Annotation: Subtype: Link Rect: 230, 493, 235, 501 Destination: 255 Annotation: Subtype: Link Rect: 209, 428, 214, 436 Destination: 255 Annotation: Subtype: Link Rect: 218, 376, 223, 384 Destination: 255 Annotation: Subtype: Link Rect: 246, 285, 251, 293 Destination: 255 Annotation: Subtype: Link Rect: 182, 272, 187, 280 Destination: 255 Annotation: Subtype: Link Rect: 92, 259, 97, 267 Destination: 255 Annotation: Subtype: Link Rect: 174, 259, 179, 267 Destination: 255 Annotation: Subtype: Link Rect: 112, 246, 121, 254 Destination: 255 Annotation: Subtype: Link Rect: 64, 220, 74, 228 Destination: 255 Annotation: Subtype: Link Rect: 351, 194, 375, 202 Destination: 255 Annotation: Subtype: Link Rect: 491, 181, 549, 189 Annotation: Subtype: Link Rect: 367, 168, 376, 176 Destination: 255 Annotation: Subtype: Link Rect: 414, 129, 424, 137 Destination: 255 Thumb: true Page: Label: 562 Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 209, 415, 214, 423 Destination: 78 Annotation: Subtype: Link Rect: 250, 363, 254, 371 Destination: 98 Annotation: Subtype: Link Rect: 212, 51, 221, 59 Destination: 255 Annotation: Subtype: Link Rect: 151, 484, 229, 492 Thumb: true Page: Label: 563 Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 234, 259, 243, 267 Destination: 255 Annotation: Subtype: Link Rect: 71, 194, 80, 202 Destination: 255 Annotation: Subtype: Link Rect: 145, 142, 153, 150 Destination: 255 Annotation: Subtype: Link Rect: 153, 365, 156, 373 Destination: 98 Thumb: true Page: Label: 564 Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 74, 623, 83, 631 Destination: 255 Annotation: Subtype: Link Rect: 126, 532, 135, 540 Destination: 255 Annotation: Subtype: Link Rect: 76, 181, 85, 189 Destination: 310 Annotation: Subtype: Link Rect: 102, 181, 112, 189 Destination: 310 Annotation: Subtype: Link Rect: 334, 467, 338, 475 Destination: 149 Annotation: Subtype: Link Rect: 365, 350, 370, 358 Destination: 170 Annotation: Subtype: Link Rect: 467, 337, 476, 345 Destination: 310 Annotation: Subtype: Link Rect: 494, 337, 503, 345 Destination: 310 Annotation: Subtype: Link Rect: 333, 246, 338, 254 Destination: 170 Annotation: Subtype: Link Rect: 459, 207, 463, 215 Destination: 195 Annotation: Subtype: Link Rect: 368, 168, 377, 176 Destination: 310 Annotation: Subtype: Link Rect: 392, 142, 397, 150 Destination: 195 Annotation: Subtype: Link Rect: 415, 103, 424, 111 Destination: 310 Annotation: Subtype: Link Rect: 361, 77, 365, 85 Destination: 195 Thumb: true Page: Label: 565 Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 250, 246, 259, 254 Destination: 310 Annotation: Subtype: Link Rect: 277, 246, 286, 254 Destination: 310 Annotation: Subtype: Link Rect: 90, 181, 99, 189 Destination: 310 Annotation: Subtype: Link Rect: 70, 155, 79, 163 Destination: 310 Annotation: Subtype: Link Rect: 70, 116, 79, 124 Destination: 310 Annotation: Subtype: Link Rect: 207, 51, 215, 59 Destination: 310 Annotation: Subtype: Link Rect: 453, 272, 461, 280 Destination: 310 Annotation: Subtype: Link Rect: 106, 341, 183, 349 Thumb: true Page: Label: 566 Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 275, 220, 284, 228 Destination: 255 Annotation: Subtype: Link Rect: 98, 168, 108, 176 Destination: 255 Annotation: Subtype: Link Rect: 67, 129, 76, 137 Destination: 255 Annotation: Subtype: Link Rect: 274, 116, 284, 124 Destination: 255 Annotation: Subtype: Link Rect: 102, 90, 111, 98 Destination: 255 Annotation: Subtype: Link Rect: 127, 64, 136, 72 Destination: 255 Annotation: Subtype: Link Rect: 309, 207, 332, 215 Destination: 255 Annotation: Subtype: Link Rect: 482, 181, 492, 189 Destination: 255 Annotation: Subtype: Link Rect: 326, 155, 331, 163 Destination: 255 Annotation: Subtype: Link Rect: 417, 77, 422, 85 Destination: 255 Annotation: Subtype: Link Rect: 351, 64, 360, 72 Destination: 255 Annotation: Subtype: Link Rect: 467, 51, 476, 59 Destination: 255 Thumb: true Page: Label: 567 Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 111, 428, 120, 436 Destination: 255 Annotation: Subtype: Link Rect: 274, 363, 284, 371 Destination: 255 Annotation: Subtype: Link Rect: 232, 311, 236, 319 Destination: 255 Annotation: Subtype: Link Rect: 121, 285, 130, 293 Destination: 255 Annotation: Subtype: Link Rect: 164, 233, 173, 241 Destination: 255 Annotation: Subtype: Link Rect: 275, 233, 284, 241 Destination: 255 Annotation: Subtype: Link Rect: 88, 220, 97, 228 Destination: 310 Annotation: Subtype: Link Rect: 118, 181, 127, 189 Destination: 310 Annotation: Subtype: Link Rect: 99, 103, 108, 111 Destination: 310 Annotation: Subtype: Link Rect: 275, 77, 284, 85 Destination: 255 Annotation: Subtype: Link Rect: 174, 64, 183, 72 Destination: 310 Annotation: Subtype: Link Rect: 215, 51, 224, 59 Destination: 310 Annotation: Subtype: Link Rect: 488, 363, 497, 371 Destination: 310 Annotation: Subtype: Link Rect: 345, 311, 354, 319 Destination: 310 Annotation: Subtype: Link Rect: 536, 246, 545, 254 Destination: 255 Annotation: Subtype: Link Rect: 476, 233, 485, 241 Destination: 310 Annotation: Subtype: Link Rect: 329, 220, 338, 228 Destination: 310 Annotation: Subtype: Link Rect: 511, 194, 520, 202 Destination: 310 Annotation: Subtype: Link Rect: 376, 129, 385, 137 Destination: 310 Annotation: Subtype: Link Rect: 513, 90, 522, 98 Destination: 310 Annotation: Subtype: Link Rect: 309, 51, 544, 59 Thumb: true Page: Label: 568 Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 210, 519, 215, 527 Destination: 255 Annotation: Subtype: Link Rect: 197, 506, 206, 514 Destination: 310 Annotation: Subtype: Link Rect: 64, 467, 73, 475 Destination: 310 Annotation: Subtype: Link Rect: 75, 454, 80, 462 Destination: 255 Annotation: Subtype: Link Rect: 279, 259, 284, 267 Destination: 255 Annotation: Subtype: Link Rect: 177, 220, 186, 228 Destination: 310 Annotation: Subtype: Link Rect: 80, 129, 102, 137 Destination: 310 Thumb: true Page: Label: 569 Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 125, 488, 133, 497 Annotation: Subtype: Link Rect: 135, 487, 278, 495 Annotation: Subtype: Link Rect: 92, 475, 101, 484 Annotation: Subtype: Link Rect: 103, 474, 246, 482 Annotation: Subtype: Link Rect: 131, 462, 139, 471 Annotation: Subtype: Link Rect: 141, 461, 284, 469 Annotation: Subtype: Link Rect: 117, 449, 125, 458 Annotation: Subtype: Link Rect: 127, 448, 270, 456 Annotation: Subtype: Link Rect: 125, 436, 133, 445 Annotation: Subtype: Link Rect: 135, 435, 278, 443 Annotation: Subtype: Link Rect: 98, 423, 106, 432 Annotation: Subtype: Link Rect: 108, 422, 251, 430 Annotation: Subtype: Link Rect: 137, 410, 146, 419 Annotation: Subtype: Link Rect: 148, 409, 272, 417 Annotation: Subtype: Link Rect: 45, 396, 63, 404 Thumb: true Page: Label: 570 Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 386, 448, 457, 456 Thumb: true Checksum: cc313866 Type: CRC32 Checksum: 9abadb1c22c1b14fa4f519bf1166c82c Type: MD5 Checksum: 53f7fde850799c6eae44e735aac4b5bd6e16134a Type: SHA-1 Checksum: f6a60753529b4c92106770b5c74812e3eed1b07836fa3d87658c351f1faf6b53 Type: SHA-256