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Destination: mk:title Children: Item: Title: 1 Introduction Destination: mk:H1_1 Item: Title: 2 Experimental part Destination: mk:H1_2 Children: Item: Title: 2.1 Reagents and standards Destination: mk:H2_1 Item: Title: 2.2 Chiral columns Destination: mk:H2_2 Item: Title: 2.3 Instrumentation Destination: mk:H2_3 Item: Title: 2.4 Human samples Destination: mk:H2_4 Item: Title: 2.5 Sample preparation Destination: mk:H2_5 Children: Item: Title: 2.5.1 Plasma, oral fluid and urine Destination: mk:H3_6 Item: Title: 2.5.2 Sweat Destination: mk:H3_7 Item: Title: 2.6 Method development and validation Destination: mk:H2_8 Item: Title: 3 Results and discussion Destination: mk:H1_3 Children: Item: Title: 3.1 Enantioselective method development (chiral column and mobile phase selection) Destination: mk:H2_9 Item: Title: 3.2 Application to biological samples Destination: mk:H2_10 Children: Item: Title: 3.2.1 Enantioselective metabolism and pharmacokinetics of MDMA Destination: mk:H3_11 Item: Title: 3.2.2 Phase-1 metabolites of MDMA Destination: mk:H3_12 Item: Title: 3.2.3 Comparison of results obtained from plasma, oral fluid, sweat and urine Destination: mk:H3_13 Item: Title: 4 Conclusions Destination: mk:H1_4 Item: Title: CRediT authorship contribution statement Destination: mk:H1_5 Item: Title: Declaration of Competing Interest Destination: mk:HH1_2 Item: Title: Acknowledgements Destination: mk:HH1_3 Item: Title: References Destination: mk:HH2_1 Info: Title: Development of enantioselective high-performance liquid chromatography-tandem mass spectrometry method for the quantitative determination of 3,4-methylenedioxy-methamphetamine (MDMA) and its phase-1 metabolites in human biological fluids Author: Alfredo Fabrizio Lo Faro Subject: Journal of Pharmaceutical and Biomedical Analysis, 238 (2024) 115768. doi:10.1016/j.jpba.2023.115768 Keywords: Chiral HPLC,Enantioselective metabolism,"Enantioseparation, MDMA and metabolites" Creator: Elsevier Producer: Acrobat Distiller 8.1.0 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sciencedirect.com true 10.1016/j.jpba.2023.115768 2010-04-23 application/pdf 10.1016/j.jpba.2023.115768 Elsevier B.V. Journal of Pharmaceutical and Biomedical Analysis, 238 (2024) 115768. doi:10.1016/j.jpba.2023.115768 Chiral HPLC Enantioselective metabolism Enantioseparation, MDMA and metabolites Development of enantioselective high-performance liquid chromatography-tandem mass spectrometry method for the quantitative determination of 3,4-methylenedioxy-methamphetamine (MDMA) and its phase-1 metabolites in human biological fluids Alfredo Fabrizio Lo Faro Giorgia Sprega Diletta Beradinelli Anstasio Tini Lourdes Poyatos Esther Papaseit Paolo Berretta Alessandro Di Giorgi Magì Farre Nino Takaishvili Tivadar Farkas Francesco Paolo Busardò Bezhan Chankvetadze VoR 2nd December 2023 Acrobat Distiller 8.1.0 (Windows) Chiral HPLC,Enantioselective metabolism,"Enantioseparation, MDMA and metabolites" 2nd December 2023 sciencedirect.com elsevier.com true 2010-04-23 10.1016/j.jpba.2023.115768 noindex journal © 2023 The Authors. Published by Elsevier B.V. 2024-01-20 20 January 2024 10.1016/j.jpba.2023.115768 0731-7085 115768 Journal of Pharmaceutical and Biomedical Analysis 115768 https://doi.org/10.1016/j.jpba.2023.115768 238 2023-12-02T08:39:19 Elsevier 2023-12-02T09:35:21 2023-12-02T09:35:21 uuid:1b499bed-4ce8-4c0c-b682-0d58baae1cbe uuid:b6ed5266-03cb-4855-90c0-636283357f42 True Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 155, 537, 415, 547 Flags: Print Destination: 587 Annotation: Subtype: Link Rect: 116, 524, 280, 534 Flags: Print Destination: 587 Annotation: Subtype: Link Rect: 280, 524, 453, 534 Flags: Print Destination: 587 Annotation: Subtype: Link Rect: 453, 524, 460, 534 Flags: Print Destination: 587 Annotation: Subtype: Link Rect: 116, 511, 199, 521 Flags: Print Destination: 587 Annotation: Subtype: Link Rect: 199, 511, 328, 521 Flags: Print Destination: 587 Annotation: Subtype: Link Rect: 328, 516, 334, 526 Flags: Print Destination: 587 Annotation: Subtype: Link Rect: 335, 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