bfa9f536223e05d52f5290afce090a06  302176.pdf
7699fdae5f2711e9359566150ee571d2ce90c8e6  302176.pdf
9a341cc5588be72ad4c893cbbaf1d658850d02ba6f353bec60d04ad6317758dd  302176.pdf

Title:           Matching-Adjusted Indirect Comparison of the Efficacy at Week 32 of Tralokinumab and Dupilumab in the Treatment of Moderate-to-Severe Atopic Dermatitis
Subject:         Dermatology and Therapy, https://doi.org/10.1007/s13555-024-01143-x
Keywords:        Atopic dermatitis; Dupilumab; Matching-adjusted indirect comparison; Topical corticosteroids; Tralokinumab
Author:          Tiago Torres 
Creator:         Springer
Producer:        Acrobat Distiller 10.1.8 (Windows)
CreationDate:    Fri Apr 12 06:38:02 2024 CEST
ModDate:         Mon Apr 22 19:27:50 2024 CEST
Custom Metadata: yes
Metadata Stream: yes
Tagged:          no
UserProperties:  no
Suspects:        no
Form:            AcroForm
JavaScript:      no
Pages:           10
Encrypted:       no
Page size:       595.276 x 790.866 pts
Page rot:        0
File size:       716663 bytes
Optimized:       yes
PDF version:     1.4


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
UHYDYT+AdvSTONE-R                    Type 1C           Custom           yes yes no     433  0
CNFPTT+AdvPTimes                     Type 1C           WinAnsi          yes yes no     454  0
PYQWWB+AdvSTONE-SB                   Type 1C           MacRoman         yes yes no     434  0
CYLKWL+AdvPSSym                      Type 1C           Custom           yes yes no     437  0
QAESEP+AdvSTONESF-R                  Type 1C           WinAnsi          yes yes no     439  0
IBBHKU+AdvSTONE-SBI                  Type 1C           MacRoman         yes yes no     438  0
LTPTRY+AdvTir_symb                   Type 1C           WinAnsi          yes yes no     445  0
LMOTSK+AdvSTONE-I                    Type 1C           WinAnsi          yes yes no     443  0
JJLHWC+AdvPSSPS-AS                   Type 1C           Custom           yes yes yes    448  0
SVQDNI+AdvP4C4E74                    Type 1C           Custom           yes yes no     449  0
RBKQCM+AdvSTONESF-B                  Type 1C           WinAnsi          yes yes no     168  0
HCRCGW+AdvOT8f27407c.BI              Type 1C           Custom           yes yes yes    162  0
CQNYJE+AdvOT6cddfb43.B               Type 1C           Custom           yes yes yes    218  0
GUOGVN+AdvOT2015df00                 Type 1C           Custom           yes yes yes    220  0
RMDVVX+AdvOT1a356080.I               Type 1C           Custom           yes yes yes    221  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2025-01-11 02:46:25 CET
 RepresentationInformation: 302176.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2025-01-10 14:42:06 CET
  Size: 716663
  Format: PDF
  Version: 1.4
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: Linearized PDF
  PDFMetadata: 
   Objects: 525
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseOutlines
    Language: EN
    Outlines: 
     Item: 
      Title: Matching-Adjusted Indirect Comparison of the Efficacy at Week 32 of Tralokinumab and Dupilumab in the Treatment of Moderate-to-Severe Atopic Dermatitis
      Destination: Title
      Children: 
       Item: 
        Title: Abstract
        Destination: Abs1
        Children: 
         Item: 
          Title: Introduction
          Destination: ASec1
         Item: 
          Title: Methods
          Destination: ASec2
         Item: 
          Title: Results
          Destination: ASec3
         Item: 
          Title: Conclusion
          Destination: ASec4
       Item: 
        Title: Introduction
        Destination: Sec1
       Item: 
        Title: Methods
        Destination: Sec2
        Children: 
         Item: 
          Title: MAIC Methods and Source Data
          Destination: Sec3
         Item: 
          Title: Matching Trial Populations
          Destination: Sec4
         Item: 
          Title: Study Outcomes
          Destination: Sec5
       Item: 
        Title: Results
        Destination: Sec6
        Children: 
         Item: 
          Title: Matching Populations
          Destination: Sec7
         Item: 
          Title: Clinical Outcomes
          Destination: Sec8
         Item: 
          Title: Patient-Reported outcomes
          Destination: Sec9
       Item: 
        Title: Discussion
        Destination: Sec10
       Item: 
        Title: Conclusion
        Destination: Sec11
       Item: 
        Title: Author Contributions
        Destination: ACont
       Item: 
        Title: Data Availability
        Destination: Ack
       Item: 
        Title: References
        Destination: Bib1
   Info: 
    Title: Matching-Adjusted Indirect Comparison of the Efficacy at Week 32 of Tralokinumab and Dupilumab in the Treatment of Moderate-to-Severe Atopic Dermatitis
    Author: Tiago Torres 
    Subject: Dermatology and Therapy, https://doi.org/10.1007/s13555-024-01143-x
    Keywords: Atopic dermatitis; Dupilumab; Matching-adjusted indirect comparison; Topical corticosteroids; Tralokinumab
    Creator: Springer
    Producer: Acrobat Distiller 10.1.8 (Windows)
    CreationDate: Fri Apr 12 07:08:02 CEST 2024
    ModDate: Mon Apr 22 19:57:50 CEST 2024
   ID: 0xd7d590fc047f36a0d70661bec45e03ec, 0x100388fef85a04479374444fa285a61e
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1894
      ImageHeight: 1465
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: Perceptual
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1894
      ImageHeight: 427
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: Perceptual
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1894
      ImageHeight: 619
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: Perceptual
   Fonts: 
    Type1: 
     Font: 
      BaseFont: JJLHWC+AdvPSSPS-AS
      FontSubset: true
      FirstChar: 38
      LastChar: 40
      FontDescriptor: 
       FontName: JJLHWC+AdvPSSPS-AS
       Flags: Symbolic
       FontBBox: 0, -250, 1052, 947
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: SVQDNI+AdvP4C4E74
      FontSubset: true
      FirstChar: 2
      LastChar: 4
      FontDescriptor: 
       FontName: SVQDNI+AdvP4C4E74
       Flags: Symbolic
       FontBBox: -20, -958, 1114, 770
       FontFile3: true
      EncodingDictionary: 
       Differences: true
     Font: 
      BaseFont: HCRCGW+AdvOT8f27407c.BI
      FontSubset: true
      FirstChar: 63
      LastChar: 123
      FontDescriptor: 
       FontName: HCRCGW+AdvOT8f27407c.BI
       Flags: Symbolic
       FontBBox: -218, -312, 1062, 812
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: CNFPTT+AdvPTimes
      FontSubset: true
      FirstChar: 32
      LastChar: 254
      FontDescriptor: 
       FontName: CNFPTT+AdvPTimes
       Flags: Serif, Nonsymbolic
       FontBBox: -166, -208, 1000, 729
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: RBKQCM+AdvSTONESF-B
      FontSubset: true
      FirstChar: 32
      LastChar: 177
      FontDescriptor: 
       FontName: RBKQCM+AdvSTONESF-B
       Flags: Nonsymbolic
       FontBBox: -156, -239, 1531, 781
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: UHYDYT+AdvSTONE-R
      FontSubset: true
      FirstChar: 18
      LastChar: 255
      FontDescriptor: 
       FontName: UHYDYT+AdvSTONE-R
       Flags: Serif, Nonsymbolic
       FontBBox: -197, -239, 1270, 770
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: PYQWWB+AdvSTONE-SB
      FontSubset: true
      FirstChar: 32
      LastChar: 255
      FontDescriptor: 
       FontName: PYQWWB+AdvSTONE-SB
       Flags: Serif, Nonsymbolic
       FontBBox: -187, -250, 1312, 770
       FontFile3: true
      Encoding: MacRomanEncoding
     Font: 
      BaseFont: CYLKWL+AdvPSSym
      FontSubset: true
      FirstChar: 2
      LastChar: 4
      FontDescriptor: 
       FontName: CYLKWL+AdvPSSym
       Flags: Serif, Symbolic
       FontBBox: -177, -291, 1083, 1010
       FontFile3: true
      EncodingDictionary: 
       Differences: true
     Font: 
      BaseFont: IBBHKU+AdvSTONE-SBI
      FontSubset: true
      FirstChar: 32
      LastChar: 255
      FontDescriptor: 
       FontName: IBBHKU+AdvSTONE-SBI
       Flags: Serif, Nonsymbolic
       FontBBox: -197, -250, 1333, 760
       FontFile3: true
      Encoding: MacRomanEncoding
     Font: 
      BaseFont: QAESEP+AdvSTONESF-R
      FontSubset: true
      FirstChar: 32
      LastChar: 177
      FontDescriptor: 
       FontName: QAESEP+AdvSTONESF-R
       Flags: Nonsymbolic
       FontBBox: -177, -239, 1291, 760
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: CQNYJE+AdvOT6cddfb43.B
      FontSubset: true
      FirstChar: 46
      LastChar: 121
      FontDescriptor: 
       FontName: CQNYJE+AdvOT6cddfb43.B
       Flags: Serif, Symbolic
       FontBBox: -187, -270, 1041, 843
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: LMOTSK+AdvSTONE-I
      FontSubset: true
      FirstChar: 32
      LastChar: 177
      FontDescriptor: 
       FontName: LMOTSK+AdvSTONE-I
       Flags: Serif, Nonsymbolic
       FontBBox: -208, -250, 1291, 760
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: GUOGVN+AdvOT2015df00
      FontSubset: true
      FirstChar: 37
      LastChar: 149
      FontDescriptor: 
       FontName: GUOGVN+AdvOT2015df00
       Flags: Serif, Symbolic
       FontBBox: -177, -270, 1031, 833
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: LTPTRY+AdvTir_symb
      FontSubset: true
      FirstChar: 32
      LastChar: 177
      FontDescriptor: 
       FontName: LTPTRY+AdvTir_symb
       Flags: Serif, Nonsymbolic
       FontBBox: -166, -208, 1000, 729
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: RMDVVX+AdvOT1a356080.I
      FontSubset: true
      FirstChar: 50
      LastChar: 114
      FontDescriptor: 
       FontName: RMDVVX+AdvOT1a356080.I
       Flags: Symbolic
       FontBBox: -208, -291, 1083, 843
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 5.6-c142 87.162696, 2019/10/10-02:41:22        ">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:xmp="http://ns.adobe.com/xap/1.0/"
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/"
            xmlns:dc="http://purl.org/dc/elements/1.1/"
            xmlns:crossmark="http://crossref.org/crossmark/1.0/"
            xmlns:prism="http://prismstandard.org/namespaces/basic/2.0/"
            xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/"
            xmlns:jav="http://www.niso.org/schemas/jav/1.0/"
            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/"
            xmlns:stEvt="http://ns.adobe.com/xap/1.0/sType/ResourceEvent#"
            xmlns:pdfaid="http://www.aiim.org/pdfa/ns/id/"
            xmlns:sn="http://springernature.com/ns/xmpExtensions/2.0/"
            xmlns:author="http://springernature.com/ns/xmpExtensions/2.0/authorInfo/"
            xmlns:pdfaExtension="http://www.aiim.org/pdfa/ns/extension/"
            xmlns:pdfaSchema="http://www.aiim.org/pdfa/ns/schema#"
            xmlns:pdfaProperty="http://www.aiim.org/pdfa/ns/property#"
            xmlns:pdfaType="http://www.aiim.org/pdfa/ns/type#"
            xmlns:pdfaField="http://www.aiim.org/pdfa/ns/field#">
         <xmp:CreateDate>2024-04-12T10:08:02+05:30</xmp:CreateDate>
         <xmp:CreatorTool>Springer</xmp:CreatorTool>
         <xmp:ModifyDate>2024-04-22T22:57:50+05:30</xmp:ModifyDate>
         <xmp:MetadataDate>2024-04-22T22:57:50+05:30</xmp:MetadataDate>
         <pdf:Producer>Acrobat Distiller 10.1.8 (Windows)</pdf:Producer>
         <pdf:Keywords>Atopic dermatitis; Dupilumab; Matching-adjusted indirect comparison; Topical corticosteroids; Tralokinumab</pdf:Keywords>
         <dc:format>application/pdf</dc:format>
         <dc:identifier>https://doi.org/10.1007/s13555-024-01143-x</dc:identifier>
         <dc:publisher>
            <rdf:Bag>
               <rdf:li>Springer Healthcare</rdf:li>
            </rdf:Bag>
         </dc:publisher>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Dermatology and Therapy, https://doi.org/10.1007/s13555-024-01143-x</rdf:li>
            </rdf:Alt>
         </dc:description>
         <dc:subject>
            <rdf:Bag>
               <rdf:li>Atopic dermatitis</rdf:li>
               <rdf:li>Dupilumab</rdf:li>
               <rdf:li>Matching-adjusted indirect comparison</rdf:li>
               <rdf:li>Topical corticosteroids</rdf:li>
               <rdf:li>Tralokinumab</rdf:li>
            </rdf:Bag>
         </dc:subject>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Matching-Adjusted Indirect Comparison of the Efficacy at Week 32 of Tralokinumab and Dupilumab in the Treatment of Moderate-to-Severe Atopic Dermatitis</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Tiago Torres </rdf:li>
               <rdf:li>Anne Sohrt Petersen </rdf:li>
               <rdf:li>Ulla Ivens </rdf:li>
               <rdf:li>Albert Bosch Vilaro </rdf:li>
               <rdf:li>John Stinson </rdf:li>
               <rdf:li>José Manuel Carrascosa </rdf:li>
            </rdf:Seq>
         </dc:creator>
         <crossmark:DOI>10.1007/s13555-024-01143-x</crossmark:DOI>
         <crossmark:MajorVersionDate>2010-04-23</crossmark:MajorVersionDate>
         <crossmark:CrossmarkDomainExclusive>true</crossmark:CrossmarkDomainExclusive>
         <crossmark:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>springer.com</rdf:li>
               <rdf:li>springerlink.com</rdf:li>
            </rdf:Seq>
         </crossmark:CrossMarkDomains>
         <prism:url>https://doi.org/10.1007/s13555-024-01143-x</prism:url>
         <prism:doi>10.1007/s13555-024-01143-x</prism:doi>
         <prism:issn>2190-9172</prism:issn>
         <prism:volume>14</prism:volume>
         <prism:number>4</prism:number>
         <prism:startingPage>983</prism:startingPage>
         <prism:endingPage>992</prism:endingPage>
         <prism:aggregationType>journal</prism:aggregationType>
         <prism:publicationName>Dermatology and Therapy</prism:publicationName>
         <prism:copyright>The Author(s)</prism:copyright>
         <pdfx:CrossmarkMajorVersionDate>2010-04-23</pdfx:CrossmarkMajorVersionDate>
         <pdfx:CrossmarkDomainExclusive>true</pdfx:CrossmarkDomainExclusive>
         <pdfx:doi>10.1007/s13555-024-01143-x</pdfx:doi>
         <pdfx:robots>noindex</pdfx:robots>
         <pdfx:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>springer.com</rdf:li>
               <rdf:li>springerlink.com</rdf:li>
            </rdf:Seq>
         </pdfx:CrossMarkDomains>
         <jav:journal_article_version>VoR</jav:journal_article_version>
         <xmpMM:DocumentID>uuid:98dafde3-fe7a-4c2f-a15d-996114c730e1</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:77df588a-57d0-49f8-8d79-d03299af733a</xmpMM:InstanceID>
         <xmpMM:RenditionClass>default</xmpMM:RenditionClass>
         <xmpMM:VersionID>1</xmpMM:VersionID>
         <xmpMM:History>
            <rdf:Seq>
               <rdf:li rdf:parseType="Resource">
                  <stEvt:action>converted</stEvt:action>
                  <stEvt:instanceID>uuid:3e957822-03a3-475b-b6b5-f17cc83375bc</stEvt:instanceID>
                  <stEvt:parameters>converted to PDF/A-2b</stEvt:parameters>
                  <stEvt:softwareAgent>pdfToolbox</stEvt:softwareAgent>
                  <stEvt:when>2024-04-22T22:57:11+05:30</stEvt:when>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <stEvt:action>converted</stEvt:action>
                  <stEvt:instanceID>uuid:67f5a94c-4fb0-4919-a125-3a8379a7ed1c</stEvt:instanceID>
                  <stEvt:parameters>converted to PDF/A-2b</stEvt:parameters>
                  <stEvt:softwareAgent>pdfToolbox</stEvt:softwareAgent>
                  <stEvt:when>2024-04-22T22:57:50+05:30</stEvt:when>
               </rdf:li>
            </rdf:Seq>
         </xmpMM:History>
         <pdfaid:part>2</pdfaid:part>
         <pdfaid:conformance>B</pdfaid:conformance>
         <sn:authorInfo>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <author:name>Tiago Torres</author:name>
                  <author:orcid>http://orcid.org/0000-0003-0404-0870</author:orcid>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <author:name>Anne Sohrt Petersen</author:name>
                  <author:orcid>http://orcid.org/0000-0001-7286-5239</author:orcid>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <author:name>Ulla Ivens</author:name>
                  <author:orcid>http://orcid.org/0009-0008-2381-7327</author:orcid>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <author:name>Albert Bosch Vilaro</author:name>
                  <author:orcid>http://orcid.org/0009-0004-2806-808X</author:orcid>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <author:name>John Stinson</author:name>
                  <author:orcid>http://orcid.org/0009-0009-5230-574X</author:orcid>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <author:name>José Manuel Carrascosa</author:name>
                  <author:orcid>http://orcid.org/0000-0003-4266-0771</author:orcid>
               </rdf:li>
            </rdf:Bag>
         </sn:authorInfo>
         <pdfaExtension:schemas>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/pdfx/1.3/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdfx</pdfaSchema:prefix>
                  <pdfaSchema:schema>Adobe Document Info PDF eXtension Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:MajorVersionDate</pdfaProperty:description>
                           <pdfaProperty:name>CrossmarkMajorVersionDate</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:CrossmarkDomainExclusive</pdfaProperty:description>
                           <pdfaProperty:name>CrossmarkDomainExclusive</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:DOI</pdfaProperty:description>
                           <pdfaProperty:name>doi</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:CrosMarkDomains</pdfaProperty:description>
                           <pdfaProperty:name>CrossMarkDomains</pdfaProperty:name>
                           <pdfaProperty:valueType>seq Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>A name object indicating whether the document has been modified to include trapping information</pdfaProperty:description>
                           <pdfaProperty:name>robots</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>ID of PDF/X standard</pdfaProperty:description>
                           <pdfaProperty:name>GTS_PDFXVersion</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Conformance level of PDF/X standard</pdfaProperty:description>
                           <pdfaProperty:name>GTS_PDFXConformance</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Company creating the PDF</pdfaProperty:description>
                           <pdfaProperty:name>Company</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Date when document was last modified</pdfaProperty:description>
                           <pdfaProperty:name>SourceModified</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://crossref.org/crossmark/1.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>crossmark</pdfaSchema:prefix>
                  <pdfaSchema:schema>Crossmark Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Usual same as prism:doi</pdfaProperty:description>
                           <pdfaProperty:name>DOI</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The date when a publication was publishe.</pdfaProperty:description>
                           <pdfaProperty:name>MajorVersionDate</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>CrossmarkDomainExclusive</pdfaProperty:description>
                           <pdfaProperty:name>CrossmarkDomainExclusive</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>CrossMarkDomains</pdfaProperty:description>
                           <pdfaProperty:name>CrossMarkDomains</pdfaProperty:name>
                           <pdfaProperty:valueType>seq Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://prismstandard.org/namespaces/basic/2.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>prism</pdfaSchema:prefix>
                  <pdfaSchema:schema>Prism Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary.</pdfaProperty:description>
                           <pdfaProperty:name>url</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). </pdfaProperty:description>
                           <pdfaProperty:name>doi</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version.</pdfaProperty:description>
                           <pdfaProperty:name>issn</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Volume number</pdfaProperty:description>
                           <pdfaProperty:name>volume</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Issue number</pdfaProperty:description>
                           <pdfaProperty:name>number</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Starting page</pdfaProperty:description>
                           <pdfaProperty:name>startingPage</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Ending page</pdfaProperty:description>
                           <pdfaProperty:name>endingPage</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. </pdfaProperty:description>
                           <pdfaProperty:name>aggregationType</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Title of the magazine, or other publication, in which a resource was/will be published. Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.”</pdfaProperty:description>
                           <pdfaProperty:name>publicationName</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Copyright</pdfaProperty:description>
                           <pdfaProperty:name>copyright</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/pdf/1.3/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdf</pdfaSchema:prefix>
                  <pdfaSchema:schema>Adobe PDF Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>A name object indicating whether the document has been modified to include trapping information</pdfaProperty:description>
                           <pdfaProperty:name>Trapped</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/xap/1.0/mm/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>xmpMM</pdfaSchema:prefix>
                  <pdfaSchema:schema>XMP Media Management Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>UUID based identifier for specific incarnation of a document</pdfaProperty:description>
                           <pdfaProperty:name>InstanceID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>The common identifier for all versions and renditions of a document.</pdfaProperty:description>
                           <pdfaProperty:name>DocumentID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>The common identifier for all versions and renditions of a document.</pdfaProperty:description>
                           <pdfaProperty:name>OriginalDocumentID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>A reference to the original document from which this one is derived. It is a minimal reference; missing components can be assumed to be unchanged. For example, a new version might only need to specify the instance ID and version number of the previous version, or a rendition might only need to specify the instance ID and rendition class of the original.</pdfaProperty:description>
                           <pdfaProperty:name>DerivedFrom</pdfaProperty:name>
                           <pdfaProperty:valueType>ResourceRef</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
                  <pdfaSchema:valueType>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaType:description>Identifies a portion of a document. This can be a position at which the document has been changed since the most recent event history (stEvt:changed). For a resource within an xmpMM:Ingredients list, the ResourceRef uses this type to identify both the portion of the containing document that refers to the resource, and the portion of the referenced resource that is referenced.</pdfaType:description>
                           <pdfaType:namespaceURI>http://ns.adobe.com/xap/1.0/sType/Part#</pdfaType:namespaceURI>
                           <pdfaType:prefix>stPart</pdfaType:prefix>
                           <pdfaType:type>Part</pdfaType:type>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:valueType>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://www.aiim.org/pdfa/ns/id/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdfaid</pdfaSchema:prefix>
                  <pdfaSchema:schema>PDF/A ID Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Part of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>part</pdfaProperty:name>
                           <pdfaProperty:valueType>Integer</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Amendment of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>amd</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Conformance level of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>conformance</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:schema>Springer Nature ORCID Schema</pdfaSchema:schema>
                  <pdfaSchema:namespaceURI>http://springernature.com/ns/xmpExtensions/2.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>sn</pdfaSchema:prefix>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:name>authorInfo</pdfaProperty:name>
                           <pdfaProperty:valueType>Bag AuthorInformation</pdfaProperty:valueType>
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Author information: contains the name of each author and his/her ORCiD (ORCiD: Open Researcher and Contributor ID). An ORCiD is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors.</pdfaProperty:description>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
                  <pdfaSchema:valueType>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaType:type>AuthorInformation</pdfaType:type>
                           <pdfaType:namespaceURI>http://springernature.com/ns/xmpExtensions/2.0/authorInfo/</pdfaType:namespaceURI>
                           <pdfaType:prefix>author</pdfaType:prefix>
                           <pdfaType:description>Specifies the types of author information: name and ORCID of an author.</pdfaType:description>
                           <pdfaType:field>
                              <rdf:Seq>
                                 <rdf:li rdf:parseType="Resource">
                                    <pdfaField:name>name</pdfaField:name>
                                    <pdfaField:valueType>Text</pdfaField:valueType>
                                    <pdfaField:description>Gives the name of an author.</pdfaField:description>
                                 </rdf:li>
                                 <rdf:li rdf:parseType="Resource">
                                    <pdfaField:name>orcid</pdfaField:name>
                                    <pdfaField:valueType>URI</pdfaField:valueType>
                                    <pdfaField:description>Gives the ORCID of an author.</pdfaField:description>
                                 </rdf:li>
                              </rdf:Seq>
                           </pdfaType:field>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:valueType>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/xap/1.0/t/pg/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>xmpTPg</pdfaSchema:prefix>
                  <pdfaSchema:schema>XMP Paged-Text</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>XMP08 Spec: An ordered array of plate names that are needed to print the document (including any in contained documents).</pdfaProperty:description>
                           <pdfaProperty:name>PlateNames</pdfaProperty:name>
                           <pdfaProperty:valueType>Seq Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://www.niso.org/schemas/jav/1.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>jav</pdfaSchema:prefix>
                  <pdfaSchema:schema>NISO</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Values for Journal Article Version are one of the following:&#xA;AO = Author’s Original&#xA;SMUR = Submitted Manuscript Under Review&#xA;AM = Accepted Manuscript&#xA;P = Proof&#xA;VoR = Version of Record&#xA;CVoR = Corrected Version of Record&#xA;EVoR = Enhanced Version of Record</pdfaProperty:description>
                           <pdfaProperty:name>journal_article_version</pdfaProperty:name>
                           <pdfaProperty:valueType>Closed Choice of Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
            </rdf:Bag>
         </pdfaExtension:schemas>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 983
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 108, 586, 116, 597
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 216, 586, 225, 597
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 281, 586, 289, 597
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 138, 569, 146, 580
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 215, 569, 223, 580
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 336, 569, 344, 580
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 239, 242, 269, 251
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 44, 233, 56, 242
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 44, 233, 56, 242
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 56, 233, 203, 242
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 495, 731, 524, 760
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 56, 730, 207, 738
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Label: 984
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 110, 159, 115, 169
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 122, 159, 128, 169
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 215, 109, 221, 119
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 226, 109, 231, 119
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 455, 641, 461, 651
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 413, 591, 419, 601
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 365, 566, 371, 576
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 372, 529, 378, 539
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 478, 479, 484, 489
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 408, 454, 414, 464
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 420, 454, 432, 464
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 504, 380, 516, 389
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 319, 330, 330, 340
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 339, 330, 350, 340
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 397, 267, 408, 277
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 461, 155, 472, 165
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 480, 155, 491, 165
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 392, 93, 403, 103
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 409, 93, 421, 103
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
     Thumb: true
    Page: 
     Label: 985
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 188, 654, 200, 663
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 207, 654, 218, 663
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 244, 616, 255, 626
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 261, 616, 272, 626
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 156, 355, 168, 365
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 177, 355, 188, 365
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 165, 330, 171, 340
       Flags: Print
       AppearanceDictionary: true
       Destination: 49
      Annotation: 
       Subtype: Link
       Rect: 60, 243, 71, 253
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 78, 243, 90, 253
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 82, 156, 93, 166
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 465, 641, 471, 651
       Flags: Print
       AppearanceDictionary: true
       Destination: 49
      Annotation: 
       Subtype: Link
       Rect: 327, 591, 338, 601
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 365, 442, 370, 452
       Flags: Print
       AppearanceDictionary: true
       Destination: 49
      Annotation: 
       Subtype: Link
       Rect: 489, 404, 501, 414
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 457, 225, 468, 235
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
     Thumb: true
    Page: 
     Label: 986
     Sequence: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 494, 260, 506, 270
       Flags: Print
       AppearanceDictionary: true
       Destination: 123
     Thumb: true
    Page: 
     Label: 987
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 131, 629, 137, 639
       Flags: Print
       AppearanceDictionary: true
       Destination: 56
      Annotation: 
       Subtype: Link
       Rect: 267, 549, 272, 559
       Flags: Print
       AppearanceDictionary: true
       Destination: 68
      Annotation: 
       Subtype: Link
       Rect: 125, 245, 131, 255
       Flags: Print
       AppearanceDictionary: true
       Destination: 68
      Annotation: 
       Subtype: Link
       Rect: 83, 171, 89, 181
       Flags: Print
       AppearanceDictionary: true
       Destination: 68
      Annotation: 
       Subtype: Link
       Rect: 499, 291, 505, 301
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 489, 142, 500, 152
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 506, 142, 518, 152
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
     Thumb: true
    Page: 
     Label: 988
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 208, 174, 219, 184
       Flags: Print
       AppearanceDictionary: true
       Destination: 123
      Annotation: 
       Subtype: Link
       Rect: 182, 112, 193, 122
       Flags: Print
       AppearanceDictionary: true
       Destination: 123
      Annotation: 
       Subtype: Link
       Rect: 520, 224, 532, 234
       Flags: Print
       AppearanceDictionary: true
       Destination: 123
      Annotation: 
       Subtype: Link
       Rect: 347, 137, 359, 147
       Flags: Print
       AppearanceDictionary: true
       Destination: 123
      Annotation: 
       Subtype: Link
       Rect: 471, 125, 482, 134
       Flags: Print
       AppearanceDictionary: true
       Destination: 123
     Thumb: true
    Page: 
     Label: 989
     Sequence: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 60, 554, 71, 564
       Flags: Print
       AppearanceDictionary: true
       Destination: 123
      Annotation: 
       Subtype: Link
       Rect: 155, 454, 167, 464
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 129, 342, 141, 352
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 148, 342, 159, 352
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 120, 317, 132, 327
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 204, 305, 215, 315
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 60, 255, 71, 265
       Flags: Print
       AppearanceDictionary: true
       Destination: 123
      Annotation: 
       Subtype: Link
       Rect: 76, 255, 87, 265
       Flags: Print
       AppearanceDictionary: true
       Destination: 123
      Annotation: 
       Subtype: Link
       Rect: 261, 243, 272, 253
       Flags: Print
       AppearanceDictionary: true
       Destination: 123
      Annotation: 
       Subtype: Link
       Rect: 89, 205, 100, 215
       Flags: Print
       AppearanceDictionary: true
       Destination: 123
      Annotation: 
       Subtype: Link
       Rect: 191, 168, 203, 178
       Flags: Print
       AppearanceDictionary: true
       Destination: 123
      Annotation: 
       Subtype: Link
       Rect: 180, 118, 191, 128
       Flags: Print
       AppearanceDictionary: true
       Destination: 123
      Annotation: 
       Subtype: Link
       Rect: 467, 703, 478, 713
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 464, 654, 476, 663
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 487, 616, 498, 626
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 506, 616, 518, 626
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 415, 467, 427, 477
       Flags: Print
       AppearanceDictionary: true
       Destination: 123
      Annotation: 
       Subtype: Link
       Rect: 305, 417, 316, 427
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 323, 417, 334, 427
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 423, 392, 434, 402
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 443, 392, 455, 402
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 305, 367, 316, 377
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 323, 367, 334, 377
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 488, 330, 499, 340
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 452, 292, 464, 302
       Flags: Print
       AppearanceDictionary: true
       Destination: 116
      Annotation: 
       Subtype: Link
       Rect: 433, 130, 444, 140
       Flags: Print
       AppearanceDictionary: true
       Destination: 123
     Thumb: true
    Page: 
     Label: 990
     Sequence: 8
     Thumb: true
    Page: 
     Label: 991
     Sequence: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 248, 419, 279, 429
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 56, 407, 248, 417
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Label: 992
     Sequence: 10
     Thumb: true
  Checksum: 529e62bb
   Type: CRC32
  Checksum: bfa9f536223e05d52f5290afce090a06
   Type: MD5
  Checksum: 7699fdae5f2711e9359566150ee571d2ce90c8e6
   Type: SHA-1
  Checksum: 9a341cc5588be72ad4c893cbbaf1d658850d02ba6f353bec60d04ad6317758dd
   Type: SHA-256