13a43521753ebafa77b7fcbd2cd60a6b NMO-37-e14921.pdf 29251d9f20302677e714bd4ea8a8918e84a8ca8f NMO-37-e14921.pdf c4d27a32ab4096a6e4bbe260fc5b5f6aa2fd91b989efe8ac7cc3b69c561ef530 NMO-37-e14921.pdf Title: Pharmacological characterization of alpha‐adrenoceptor‐mediated motor responses in the rat colon. Creator: Adobe InDesign 19.3 (Windows) Producer: Adobe PDF Library 17.0 CreationDate: Sat Dec 14 01:49:30 2024 CET ModDate: Sat Dec 14 01:49:55 2024 CET Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 10 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 3170366 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- TNJYIL+Lato-Regular CID TrueType Identity-H yes yes yes 347 0 LRJSAB+Lato-Bold CID TrueType Identity-H yes yes yes 348 0 SURIUN+STIX-Regular Type 1C Custom yes yes yes 349 0 PZNAET+Lato-Italic TrueType WinAnsi yes yes yes 350 0 KFWRMD+Lato-Regular TrueType WinAnsi yes yes yes 351 0 PFFQET+Lato-Bold TrueType WinAnsi yes yes yes 352 0 KFWRMD+Lato-Regular TrueType WinAnsi yes yes yes 242 0 MJTMGZ+Lato-Regular-SC700 TrueType WinAnsi yes yes yes 243 0 KFWRMD+Lato-Regular TrueType WinAnsi yes yes yes 244 0 MJTMGZ+Lato-Regular-SC700 TrueType WinAnsi yes yes yes 245 0 TGEJIL+HelveticaLTStd-Bold Type 1C WinAnsi yes yes no 124 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-02-17 16:58:49 CET RepresentationInformation: NMO-37-e14921.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-02-11 15:55:27 CET Size: 3170366 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 382 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseNone Language: en-US Outlines: Item: Title: Pharmacological characterization of alpha adrenoceptor-mediated motor responses in the rat colon Children: Item: Title: Abstract Item: Title: 1 | INTRODUCTION Item: Title: 2 | MATERIALS AND METHODS Children: Item: Title: 2.1 | Ethical approval Children: Item: Title: 2.1.1 | Animals and tissue samples Item: Title: 2.1.2 | Mechanical studies Item: Title: 2.1.3 | Solutions and drugs Item: Title: 2.1.4 | Experimental procedure, data analysis, and statistics Item: Title: 3 | RESULTS Children: Item: Title: 3.1 | Effect of PE on the circular and longitudinal layers from the proximal, mid, and distal colon Item: Title: 3.2 | Effect of PE on the circular in control, in the presence of atropine, phentolamine, and propranolol Item: Title: 3.3 | Effect of PE on the circular and longitudinal muscle in control conditions, in the presence of TTX, phentolamine, and apamin Item: Title: 3.4 | Effect of PE on the circular and longitudinal muscle in the presence of propranolol, yohimbine, prazosin, and RS17053 in tissue incubated with TTX Item: Title: 3.5 | Effect of isoprenaline on the circular muscle Item: Title: 4 | DISCUSSION Item: Title: 5 | CONCLUSION Item: Title: AUTHOR CONTRIBUTIONS Item: Title: ACKNOWLEDGMENTS Item: Title: FUNDING INFORMATION Item: Title: CONFLICT OF INTEREST STATEMENT Item: Title: DATA AVAILABILITY STATEMENT Item: Title: REFERENCES Info: Title: Pharmacological characterization of alpha‐adrenoceptor‐mediated motor responses in the rat colon. 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