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Destination: mk:H2_11 Item: Title: 4 Discussion Destination: mk:H1_4 Item: Title: CRediT authorship contribution statement Destination: mk:H1_5 Item: Title: Declaration of competing interest Destination: mk:HH1_3 Item: Title: Data availability Destination: datalink4 Item: Title: Acknowledgements Destination: mk:HH1_5 Item: Title: References Destination: mk:HH2_1 Info: Title: The splicing factor SF3B1 is involved in brown adipocyte thermogenic activation Author: Moisés Castellá Subject: Biochemical Pharmacology, 220 (2024) 116014. doi:10.1016/j.bcp.2023.116014 Keywords: Brown adipose tissue,Splicing,SF3B1,Pladienolide-B,Obesity Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Wed Jan 24 19:32:07 CET 2024 ModDate: Wed Jan 24 19:47:53 CET 2024 ID: 0xf4ec460d71e9e4bcb1e5baa549871f32, 0xee501fb1e79bd45e48e8a6621fb3d13c Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 236 ImageHeight: 298 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 248 ImageHeight: 271 BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type0: Font: BaseFont: VQFRRZ+CharisSIL Encoding: Identity-H ToUnicode: true Font: BaseFont: CNKTHX+CharisSIL-Italic Encoding: Identity-H ToUnicode: true Font: BaseFont: FPLMOT+TimesNewRomanPSMT Encoding: Identity-H ToUnicode: true Font: BaseFont: YFIVUZ+CharisSIL-Bold Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: DEVPBZ+STIXGeneral FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: DEVPBZ+STIXGeneral Flags: Nonsymbolic FontBBox: -178, -443, 2000, 1023 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: XPSUCB+STIX-Italic FontSubset: true FirstChar: 1 LastChar: 2 FontDescriptor: FontName: XPSUCB+STIX-Italic Flags: Nonsymbolic, Italic FontBBox: -970, -305, 1429, 1023 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: BRWWWZ+TeX_CM_Roman FontSubset: true FirstChar: 1 LastChar: 128 FontDescriptor: FontName: BRWWWZ+TeX_CM_Roman Flags: Symbolic FontBBox: -50, -180, 1000, 720 FontFile3: true ToUnicode: true Font: BaseFont: NTMBZO+TeX_CM_Maths_Italic FontSubset: true FirstChar: 1 LastChar: 127 FontDescriptor: FontName: NTMBZO+TeX_CM_Maths_Italic Flags: Symbolic FontBBox: -50, -180, 1000, 720 FontFile3: true ToUnicode: true Font: BaseFont: OJQKLH+STIX-Regular FontSubset: true FirstChar: 1 LastChar: 11 FontDescriptor: FontName: OJQKLH+STIX-Regular Flags: Nonsymbolic FontBBox: -970, -486, 2208, 1023 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: FPTJLV+TeX_CM_Maths_Symbols FontSubset: true FirstChar: 1 LastChar: 138 FontDescriptor: FontName: FPTJLV+TeX_CM_Maths_Symbols Flags: Symbolic FontBBox: -50, -180, 1000, 720 FontFile3: true ToUnicode: true Font: BaseFont: VXCJFZ+Univers FontSubset: true FirstChar: 32 LastChar: 251 FontDescriptor: FontName: VXCJFZ+Univers Flags: Symbolic FontBBox: -50, -180, 1000, 720 FontFile3: true ToUnicode: true CIDFontType2: Font: BaseFont: FPLMOT+TimesNewRomanPSMT CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: FPLMOT+TimesNewRomanPSMT Flags: Nonsymbolic FontBBox: -568, -307, 2000, 1007 FontFile2: true Font: BaseFont: YFIVUZ+CharisSIL-Bold CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: YFIVUZ+CharisSIL-Bold Flags: Nonsymbolic, ForceBold FontBBox: -720, -533, 1759, 1320 FontFile2: true Font: BaseFont: VQFRRZ+CharisSIL CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: VQFRRZ+CharisSIL Flags: Nonsymbolic FontBBox: -692, -533, 1623, 1319 FontFile2: true Font: BaseFont: CNKTHX+CharisSIL-Italic CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: CNKTHX+CharisSIL-Italic Flags: Nonsymbolic, Italic FontBBox: -716, -533, 1627, 1318 FontFile2: true XMP: application/pdf 10.1016/j.bcp.2023.116014 Elsevier Inc. Biochemical Pharmacology, 220 (2024) 116014. doi:10.1016/j.bcp.2023.116014 Brown adipose tissue Splicing SF3B1 Pladienolide-B Obesity The splicing factor SF3B1 is involved in brown adipocyte thermogenic activation Moisés Castellá Alberto Mestres-Arenas Aleix Gavaldà-Navarro Albert Blasco-Roset Tania Quesada-López Inés Romero-Carramiñana Marta Giralt Francesc Villarroya Rubén Cereijo journal Biochemical Pharmacology © 2023 The Author(s). Published by Elsevier Inc. 0006-2952 220 1 February 2024 2024-02-01 116014 116014 10.1016/j.bcp.2023.116014 https://doi.org/10.1016/j.bcp.2023.116014 2010-04-23 true 10.1016/j.bcp.2023.116014 elsevier.com sciencedirect.com http://creativecommons.org/licenses/by-nc-nd/4.0/ VoR 10.1016/j.bcp.2023.116014 noindex 2010-04-23 true 24th January 2024 sciencedirect.com elsevier.com Elsevier 2024-01-24T18:47:53 2024-01-24T18:32:07 2024-01-24T18:47:53 True 24th January 2024 Acrobat Distiller 8.1.0 (Windows) Brown adipose tissue,Splicing,SF3B1,Pladienolide-B,Obesity uuid:1b499bed-4ce8-4c0c-b682-0d58baae1cbe uuid:b6ed5266-03cb-4855-90c0-636283357f42 Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 111, 576, 117, 587 Flags: Print Destination: 524 Annotation: Subtype: Link Rect: 118, 571, 240, 582 Flags: Print Destination: 524 Annotation: Subtype: Link Rect: 240, 576, 246, 587 Flags: Print Destination: 524 Annotation: Subtype: Link Rect: 247, 571, 366, 582 Flags: Print Destination: 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