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Title:           Identification of nonsense variants in the genomes of 15 Murciano-Granadina bucks and analysis of their segregation in parent-offspring trios
Subject:         Journal of Dairy Science, 107 (2024) 11224-11238. doi:10.3168/jds.2024-24952
Keywords:        knockout; stop gain variant; protein truncation; cost of domestication hypothesis
Author:          Ke Wang
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     Item: 
      Title: Identification of nonsense variants in the genomes of 15 Murciano-Granadina bucks and analysis of their segregation in parent-offspring trios
      Children: 
       Item: 
        Title: INTRODUCTION
       Item: 
        Title: MATERIALS AND METHODS
        Children: 
         Item: 
          Title: Ethics Statement
         Item: 
          Title: Animal Material
         Item: 
          Title: Sequencing of Genomic DNA from 15 Murciano-Granadina Bucks and Bioinformatic Analysis
         Item: 
          Title: Functional Annotation of Genes Containing Nonsense Variants
         Item: 
          Title: TaqMan Open Array Genotyping of 20 Nonsense Variants with Predicted Harmful Effects
         Item: 
          Title: Sanger Sequencing of the Region Containing a Nonsense Variant in the DAXX Gene
       Item: 
        Title: RESULTS
        Children: 
         Item: 
          Title: Identification of Nonsense Variants and Their Genomic Distribution
         Item: 
          Title: Functions and Biological Essentiality of Genes Containing Nonsense Variants
         Item: 
          Title: Genotyping of Variants Predicted to Have Harmful Effects in Parent-Offspring Trios
       Item: 
        Title: DISCUSSION
        Children: 
         Item: 
          Title: The Genomic Landscape of Nonsense Variants in 15 Capra hircus Genomes
         Item: 
          Title: Data About Knockout Mice Do Not Fully Recapitulate the Consequences of Nonsense Variants in Goats
         Item: 
          Title: A Putative Nonsense Variant in the DAXX Gene Is an Artifact Produced by the Co-amplification of a Duplicated Copy
         Item: 
          Title: Implications in the Context of the Cost of Domestication Hypothesis
       Item: 
        Title: NOTES
       Item: 
        Title: REFERENCES
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  Checksum: c6659686
   Type: CRC32
  Checksum: cb6c6c80c24aa8b30051734500d2c9d4
   Type: MD5
  Checksum: e58d40b1750512bdf0560f92edae04e57a21ba1d
   Type: SHA-1
  Checksum: a3b1b0a276776ace9a5a43ce08243c2077fd6e45d6431c91b4fa33f25d0916eb
   Type: SHA-256