b690ab2398948f2a119076a2dcdcd5b9 306307.pdf 8f96eaada60d3fc6532a4fe3c2ded96c61a7e17e 306307.pdf cb59f45fbf296e90565d63e52a6f53da812d9e654f004d4b3cb8ffc0eddbb382 306307.pdf Title: Leadless pacemakers at 5-year follow-up: the Micra transcatheter pacing system post-approval registry Subject: DOI: 10.1093/eurheartj/ehae101; European Heart Journal, 45, 14, 2024-03-1.; Abstract: Background and Aims: Prior reports have demonstrated a favourable safety and efficacy profile of the Micra leadless pacemaker over mid-term follow-up; however, long-term outcomes in real-world clinical practice remain unknown. Updated performance of the Micra VR leadless pacemaker through five years from the worldwide post-approval registry (PAR) was assessed. Methods: All Micra PAR patients undergoing implant attempts were included. Endpoints included system- or procedure-related major complications and system revision rate for any cause through 60 months post-implant. Rates were compared through 36 months post-implant to a reference dataset of 2667 transvenous pacemaker patients using Fine–Gray competing risk models. Results: 1809 patients were enrolled between July 2015 and March 2018 and underwent implant attempts from 179 centres in 23 countries with a median follow-up period of 51.1 months (I Keywords: Leadless pacing; Long-term outcomes; Pacemaker; Bradycardia; Clinical trial Author: Mikhael F. 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FontBBox: -316, -235, 1219, 950 FontFile2: true Font: BaseFont: UGYMEU+GillSansNova-Heavy CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: UGYMEU+GillSansNova-Heavy Flags: Nonsymbolic, ForceBold FontBBox: -504, -287, 1375, 966 FontFile2: true XMP: uuid:155c0853-753d-4d0c-9316-2479a735cd15 uuid:7EB3E724-83A2-6FB8-3CBE-7FC800CD1A28 True Leadless pacing; Long-term outcomes; Pacemaker; Bradycardia; Clinical trial PDFlib+PDI 9.0.7p3 (C++/Win64) application/pdf 10.1093/eurheartj/ehae101 en Oxford University Press Leadless pacemakers at 5-year follow-up: the Micra transcatheter pacing system post-approval registry Mikhael F. El-Chami Christophe Garweg Nicolas Clementy Faisal Al-Samadi Saverio Iacopino Jose Luis Martinez-Sande Paul R. Roberts Claudio Tondo Jens Brock Johansen Xavier Vinolas-Prat Yong-Mei Cha Eric Grubman Pierre Bordachar Kurt Stromberg Dedra H. Fagan Jonathan P. Piccini DOI: 10.1093/eurheartj/ehae101; European Heart Journal, 45, 14, 2024-03-1.; Abstract: Background and Aims: Prior reports have demonstrated a favourable safety and efficacy profile of the Micra leadless pacemaker over mid-term follow-up; however, long-term outcomes in real-world clinical practice remain unknown. Updated performance of the Micra VR leadless pacemaker through five years from the worldwide post-approval registry (PAR) was assessed. Methods: All Micra PAR patients undergoing implant attempts were included. Endpoints included system- or procedure-related major complications and system revision rate for any cause through 60 months post-implant. Rates were compared through 36 months post-implant to a reference dataset of 2667 transvenous pacemaker patients using Fine–Gray competing risk models. Results: 1809 patients were enrolled between July 2015 and March 2018 and underwent implant attempts from 179 centres in 23 countries with a median follow-up period of 51.1 months (I © The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology. Leadless pacing Long-term outcomes Pacemaker Bradycardia Clinical trial Journal European Heart Journal © The Author(s) 2024. 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