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Title: 2.6 | Cerebrospinal fluid and plasma amyloid/tau/neurodegeneration biomarkers acquisition and analyses Destination: subsection..1.2.6 Item: Title: 2.7 | Statistical analysis Destination: subsection..1.2.7 Item: Title: 3 | RESULTS Destination: section..1.3 Children: Item: Title: 3.1 | Participants and demographics Destination: subsection..1.3.1 Item: Title: 3.2 | CMI prevalence and number Destination: subsection..1.3.2 Item: Title: 3.3 | CMI prevalence and number with age Destination: subsection..1.3.3 Item: Title: 3.4 | CMI topography Destination: subsection..1.3.4 Item: Title: 3.5 | CMI relationship with sex, APOE haplotype, and vascular risk factors in DS Destination: subsection..1.3.5 Item: Title: 3.6 | CMI relationship with fluid AT(N) biomarkers, vascular neuroimaging findings, and cognitive performance in DS Destination: subsection..1.3.6 Item: Title: 4 | DISCUSSION Destination: section..1.4 Item: Title: AUTHOR CONTRIBUTIONS Destination: section*.4 Item: Title: 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