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Destination: mk:title Children: Item: Title: Introduction Destination: mk:H1_1 Item: Title: Technical development of sCT Destination: mk:H1_2 Children: Item: Title: Data curation Destination: mk:H2_1 Item: Title: Data pre-processing and training process Destination: mk:H2_2 Item: Title: Hardware requirements Destination: mk:H2_3 Item: Title: Network selection Destination: mk:H2_4 Item: Title: Quality evaluation of a sCT image generator Destination: mk:H2_5 Children: Item: Title: Image metrics Destination: mk:H3_6 Item: Title: Dose metrics Destination: mk:H3_7 Item: Title: Patient positioning performances Destination: mk:H3_8 Item: Title: Technical challenges Destination: mk:H2_9 Item: Title: QA program Destination: mk:H1_3 Children: Item: Title: Risk analysis Destination: mk:H2_10 Item: Title: Required machine QA Destination: mk:H2_11 Item: Title: MR imaging of RT specific devices Destination: mk:H2_12 Item: Title: Comprehensive workflow testing Destination: mk:H2_13 Item: Title: Patient specific QA Destination: mk:H2_14 Item: Title: QA role in software sustainability Destination: mk:H2_15 Item: Title: Suggestions to vendors Destination: mk:H1_4 Item: Title: Discussion Destination: mk:H1_5 Item: Title: Conclusion Destination: mk:H1_6 Item: Title: CRediT authorship contribution statement Destination: mk:H1_7 Item: Title: Declaration of competing interest Destination: mk:HH1_2 Item: Title: Acknowledgments Destination: mk:HH1_3 Item: Title: Appendix A Supplementary material Destination: mk:H1_8 Item: Title: References Destination: mk:HH2_1 Info: Title: Challenges and opportunities in the development and clinical implementation of artificial intelligence based synthetic computed tomography for magnetic resonance only radiotherapy Author: Fernanda Villegas Subject: Radiotherapy and Oncology, 198 (2024) 110387. doi:10.1016/j.radonc.2024.110387 Keywords: MR-only radiotherapy,MR-only planning,Synthetic CT,Clinical implementation,Deep learning,Artificial intelligence Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Mon Aug 05 13:07:15 CEST 2024 ModDate: Mon Aug 05 13:12:56 CEST 2024 ID: 0xfe4aede83924d6e8e4b4e34002304db0, 0xba31120c4d56a4363068ed886984fea2 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 236 ImageHeight: 298 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 248 ImageHeight: 271 BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type0: Font: BaseFont: ATRTIF+TimesNewRomanPSMT Encoding: Identity-H ToUnicode: true Font: BaseFont: UNELZO+CharisSIL Encoding: Identity-H ToUnicode: true Font: BaseFont: BORSCB+CharisSIL-Bold Encoding: Identity-H ToUnicode: true Font: BaseFont: RXKESJ+CharisSIL-Italic Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: SSHIIE+TeX_CM_Maths_Italic FontSubset: true FirstChar: 1 LastChar: 127 FontDescriptor: FontName: SSHIIE+TeX_CM_Maths_Italic Flags: Symbolic FontBBox: -50, -180, 1000, 720 FontFile3: true ToUnicode: true Font: BaseFont: UUCMJS+TeX_CM_Roman FontSubset: true FirstChar: 1 LastChar: 128 FontDescriptor: FontName: UUCMJS+TeX_CM_Roman Flags: Symbolic FontBBox: -50, -180, 1000, 720 FontFile3: true ToUnicode: true Font: BaseFont: EZADIS+STIX-Regular FontSubset: true FirstChar: 1 LastChar: 7 FontDescriptor: FontName: EZADIS+STIX-Regular Flags: Nonsymbolic FontBBox: -970, -486, 2208, 1023 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: KFXZMY+TeX_CM_Maths_Symbols FontSubset: true FirstChar: 1 LastChar: 138 FontDescriptor: FontName: KFXZMY+TeX_CM_Maths_Symbols Flags: Symbolic FontBBox: -50, -180, 1000, 720 FontFile3: true ToUnicode: true Font: BaseFont: AEDTVZ+Univers FontSubset: true FirstChar: 32 LastChar: 251 FontDescriptor: FontName: AEDTVZ+Univers Flags: Symbolic FontBBox: -50, -180, 1000, 720 FontFile3: true ToUnicode: true CIDFontType2: Font: BaseFont: RXKESJ+CharisSIL-Italic CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: RXKESJ+CharisSIL-Italic Flags: Nonsymbolic, Italic FontBBox: -716, -533, 1627, 1318 FontFile2: true Font: BaseFont: ATRTIF+TimesNewRomanPSMT CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: ATRTIF+TimesNewRomanPSMT Flags: Nonsymbolic FontBBox: -568, -307, 2000, 1007 FontFile2: true Font: BaseFont: UNELZO+CharisSIL CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: UNELZO+CharisSIL Flags: Nonsymbolic FontBBox: -692, -533, 1623, 1319 FontFile2: true Font: BaseFont: BORSCB+CharisSIL-Bold CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: BORSCB+CharisSIL-Bold Flags: Nonsymbolic, ForceBold FontBBox: -720, -533, 1759, 1320 FontFile2: true XMP: application/pdf 10.1016/j.radonc.2024.110387 Elsevier B.V. Radiotherapy and Oncology, 198 (2024) 110387. doi:10.1016/j.radonc.2024.110387 MR-only radiotherapy MR-only planning Synthetic CT Clinical implementation Deep learning Artificial intelligence Challenges and opportunities in the development and clinical implementation of artificial intelligence based synthetic computed tomography for magnetic resonance only radiotherapy Fernanda Villegas Riccardo Dal Bello Emilie Alvarez-Andres Jennifer Dhont Tomas Janssen Lisa Milan Charlotte Robert Ghizela-Ana-Maria Salagean Natalia Tejedor Petra Trnková Marco Fusella Lorenzo Placidi Davide Cusumano journal Radiotherapy and Oncology © 2024 The Author(s). 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