365198adff80bc80721c01ed36cd2a3d 308604.pdf 1a518d74f696e5aeb9f842505b5d632d50376009 308604.pdf aab6d42bfb38d10d1380171b5c7323eed77e6e262c08e9d045c4beb3bf0f0f8c 308604.pdf Title: Escalating costs of innovative medicines: perspective and proposals Subject: Vallano A and Pontes C (2024) Escalating costs of innovative medicines: perspective and proposals. Front. Public Health 12:1449707. doi: 10.3389/fpubh.2024.1449707 Author: Antonio Vallano Creator: Adobe InDesign 14.0 (Windows) Producer: Adobe PDF Library 15.0 CreationDate: Thu Sep 19 10:54:21 2024 CEST ModDate: Thu Sep 19 10:54:27 2024 CEST Custom Metadata: no Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 8 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 415428 bytes Optimized: yes PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- EIAISV+MuseoSans-500 Type 1C Custom yes yes yes 1002 0 CFBWQZ+MuseoSans-300 Type 1C Custom yes yes yes 1008 0 ACCKOD+MuseoSans-700 Type 1C Custom yes yes yes 1013 0 YZYYMH+MinionPro-Regular Type 1C Custom yes yes yes 1014 0 VSPGWN+MuseoSans-300Italic Type 1C WinAnsi yes yes yes 1022 0 TPLUUR+MinionPro-It Type 1C Custom yes yes yes 226 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-03-05 02:45:52 CET RepresentationInformation: 308604.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-03-04 19:15:03 CET Size: 415428 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 1063 FreeObjects: 483 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseNone Language: en-GB Outlines: Item: Title: Escalating costs of innovative medicines: perspective and proposals Children: Item: Title: 1 Introduction Item: Title: 2 Current challenges in global pharmaceutical expenditure: the surge in medication costs and the burden on public healthcare systems Item: Title: 3 Potential solutions: towards a health-driven payment Children: Item: Title: 3.1 Ensure fair competition Item: Title: 3.2 Focus on health outcomes Item: Title: 3.3 Focus on health problems Item: Title: 3.4 Fair negotiation and collaboration Item: Title: 3.5 Shift to preventive health Item: Title: 3.6 Time for regulatory reforms Item: Title: 3.7 International cooperation Item: Title: 3.8 Effective implementation Item: Title: 4 Conclusion Item: Title: References Info: Title: Escalating costs of innovative medicines: perspective and proposals Author: Antonio Vallano Subject: Vallano A and Pontes C (2024) Escalating costs of innovative medicines: perspective and proposals. Front. 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Front. Public Health 12:1449707. doi: 10.3389/fpubh.2024.1449707 pharmaceutical costs national healthcare systems pricing strategies regulatory reforms health-driven payment model Copyright © 2024 Vallano and Pontes. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. 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