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Oncol. 14:1510278. doi: 10.3389/fonc.2024.1510278 Keywords: pembrolizumab; non-small cell lung cancer; first-line; predictive factors; high PD-L1 expression; immune check-point inhibitors Author: Aida Piedra CreationDate: Tue Dec 17 10:20:10 2024 CET ModDate: Tue Dec 17 10:20:10 2024 CET Custom Metadata: no Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 595.389 x 841.663 pts (A4) Page rot: 0 File size: 964710 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- EMCHEG+AdvTTd3a5f740 Type 1C WinAnsi yes yes no 834 0 EMCHEH+AdvTTd3a5f740+01 Type 1C MacRoman yes yes no 835 0 EMCHEI+AdvPSA18C Type 1C WinAnsi yes yes no 836 0 EMCHEJ+AdvTT9b12cd41 Type 1C WinAnsi yes yes no 840 0 EMCHEK+AdvTT9b12cd41+20 Type 1C WinAnsi yes yes no 841 0 EMCHEL+AdvPSA323 Type 1C WinAnsi yes yes no 842 0 EMCHEM+AdvTT2c8ce45a Type 1C WinAnsi yes yes no 843 0 EMCHFN+AdvTT9b12cd41+fb Type 1C Custom yes yes yes 844 0 EMCHFO+AdvTT9b12cd41+22 Type 1C Custom yes yes yes 845 0 EMCHOM+AdvTT9b12cd41+01 Type 1C MacRoman yes yes no 853 0 EMCHPM+AdvTTd168d80a.I Type 1C WinAnsi yes yes no 855 0 EMCIDM+AdvTT2c8ce45a+fb Type 1C Custom yes yes yes 170 0 EMCIDN+AdvOT1ef757c0 Type 1C WinAnsi yes yes no 171 0 EMCIDO+AdvOT1ef757c0+fb Type 1C Custom yes yes yes 172 0 EMCIDP+AdvOT1ef757c0+22 Type 1C Custom yes yes yes 174 0 EMCIEA+AdvOT1ef757c0+20 Type 1C Custom yes yes yes 181 0 EMCIHA+AdvOT7d6df7ab.I Type 1C WinAnsi yes yes no 189 0 EMCPHG+AdvOTb65e897d.B Type 1C WinAnsi yes yes no 190 0 EMCPJG+AdvTT58d178b9+03 Type 1C Custom yes yes yes 191 0 EMCPLG+AdvTTd3a5f740+fb Type 1C Custom yes yes yes 197 0 EMCPMH+AdvTTd3a5f740+20 Type 1C WinAnsi yes yes no 196 0 EMCPNH+AdvOT1ef757c0+01 Type 1C MacRoman yes yes no 198 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-03-07 02:43:14 CET RepresentationInformation: 308686.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-03-06 19:18:07 CET Size: 964710 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 918 FreeObjects: 4 IncrementalUpdates: 3 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: First-line pembrolizumab in patients with advanced non-small cell lung cancer and high PD-L1 expression: real-world data from a Spanish multicenter study Destination: bmark_513876024 Children: Item: Title: Introduction Destination: s1 Item: Title: Materials and methods Destination: s2 Item: Title: Results Destination: s3 Item: Title: Discussion Destination: s4 Item: Title: Data availability statement Destination: bmark_-1258588262 Item: Title: Ethics statement Destination: bmark_1370551237 Item: Title: Author contributions Destination: bmark_-1208584890 Item: Title: Funding Destination: bmark_1865464027 Item: Title: Conflict of interest Destination: bmark_1089982005 Item: Title: Generative AI statement Destination: bmark_-1453097031 Item: Title: Publisher’s note Destination: bmark_-1256977648 Item: Title: References Destination: bmark_2090415954 Info: Title: First-line pembrolizumab in patients with advanced non-small cell lung cancer and high PD-L1 expression: real-world data from a Spanish multicenter study Author: Aida Piedra Subject: Piedra A, Martínez-Recio S, Hernández A, Morán T, Arriola E, Recuero-Borau J, Cobo M, Cordeiro P, Mosquera J, Fernández M, García-Campelo R, Calles A, Álvarez R, Zapata-García M, Isla D, Callejo A, Iranzo P, Serra-López J, Barba A, Sullivan I, Felip E and Majem M (2024) First-line pembrolizumab in patients with advanced non-small cell lung cancer and high PD-L1 expression: real-world data from a Spanish multicenter study. Front. 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Dolores Isla Ana Callejo Patricia Iranzo Jorgina Serra-López Andrés Barba Ivana Sullivan Enriqueta Felip Margarita Majem Piedra A, Martínez-Recio S, Hernández A, Morán T, Arriola E, Recuero-Borau J, Cobo M, Cordeiro P, Mosquera J, Fernández M, García-Campelo R, Calles A, Álvarez R, Zapata-García M, Isla D, Callejo A, Iranzo P, Serra-López J, Barba A, Sullivan I, Felip E and Majem M (2024) First-line pembrolizumab in patients with advanced non-small cell lung cancer and high PD-L1 expression: real-world data from a Spanish multicenter study. Front. Oncol. 14:1510278. doi: 10.3389/fonc.2024.1510278 Copyright © 2024 Piedra, Martínez-Recio, Hernández, Morán, Arriola, Recuero-Borau, Cobo, Cordeiro, Mosquera, Fernández, García-Campelo, Calles, Álvarez, Zapata-García, Isla, Callejo, Iranzo, Serra-López, Barba, Sullivan, Felip and Majem. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. 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