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DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: The expression of VDACs and Bcl2 family genes in pituitary adenomas: clinical correlations and postsurgical outcomes Destination: bmark_851255803 Children: Item: Title: 1 Introduction Destination: s1 Item: Title: 2 Materials and methods Destination: s2 Children: Item: Title: 2.1 Participants and samples Destination: s2_1 Item: Title: 2.2 Clinical assessment Destination: s2_2 Item: Title: 2.3 Nucleic acid extraction and cDNA synthesis Destination: s2_3 Item: Title: 2.4 Analysis of the gene expression of VDACs, BAX and BAK1 Destination: s2_4 Item: Title: 2.5 Statistical analysis Destination: s2_5 Item: Title: 3 Results Destination: s3 Children: Item: Title: 3.1 Demographic and clinical characterization Destination: s3_1 Item: Title: 3.2 Distribution of clinical and therapeutic characteristics by diagnostic group Destination: s3_2 Item: Title: 3.3 Relative gene expression of the VDAC1, VDAC2, BAX, and BAK1 according to the clinical presentation of PA Destination: s3_3 Item: Title: 3.4 Correlations between the relative expressions of the VDAC1, VDAC2, BAX, and BAK1 genes by group Destination: s3_4 Item: Title: 3.5 Differential relative gene expression of VDAC1, VDAC2, BAX, and BAK1 according to the clinical behavior of the tumor Destination: s3_5 Item: Title: 4 Discussion Destination: s4 Children: Item: Title: 4.1 Clinical analysis Destination: s4_1 Item: Title: 4.2 VDAC1 and VDAC2 analysis Destination: s4_2 Item: Title: 4.3 BCL-2 family analysis Destination: s4_3 Item: Title: 4.4 Invasiveness analysis Destination: s4_4 Item: Title: 4.5 Limitations Destination: s4_5 Item: Title: 4.6 Conclusion Destination: s4_6 Item: Title: Data availability statement Destination: bmark_-1258588262 Item: Title: Ethics statement Destination: bmark_1370551237 Item: Title: Author contributions Destination: bmark_-1208584890 Item: Title: Funding Destination: bmark_1865464027 Item: Title: Acknowledgments 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Front. Endocrinol. 15:1481050. doi: 10.3389/fendo.2024.1481050 Copyright © 2024 Facundo, Magalhães, Nascimento, Azulay, Santos, Freitas, Nascimento, Rodrigues, Santos, Beckman, Abreu, Silva, Carneiro, Oliveira Neto, Gil da Costa, Corcoy, Mato and Faria. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. pituitary adenoma VDAC bax BAK apoptosis tumor regrowth The expression of VDACs and Bcl2 family genes in pituitary adenomas: clinical correlations and postsurgical outcomes pituitary adenoma; VDAC; bax; BAK; apoptosis; tumor regrowth True https://www.frontiersin.org/legal/copyright-statement Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 221, 685, 508, 706 Annotation: Subtype: Link Rect: 221, 660, 500, 681 Annotation: Subtype: Link Rect: 221, 635, 522, 656 Annotation: Subtype: Link Rect: 221, 610, 484, 631 Annotation: Subtype: Link Rect: 49, 33, 135, 40 Annotation: Subtype: Link Rect: 500, 33, 545, 40 Annotation: Subtype: Link Rect: 49, 690, 125, 705 Annotation: Subtype: Link Rect: 60, 528, 134, 535 Annotation: Subtype: Link Rect: 49, 379, 156, 386 Annotation: Subtype: Link Rect: 121, 311, 180, 318 Annotation: Subtype: Link Rect: 49, 302, 133, 309 Annotation: Subtype: Link 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