e3391feef271fc2448110bd98f516331 309293.pdf b224f3acdf2619b6fb28cc37ae5204f9923e87a7 309293.pdf 8db0274423cb1f23c606626f63047e59ead7062ce455e0afd934857fee11c8d0 309293.pdf Title: Asthma Control According to GINA 2023: Does Changing the Criteria Improve Asthma Control? Subject: Background/Objectives: Achieving disease control is the main goal in asthmatic patients in order to prevent future risks and exacerbations. There are several clinical guidelines that set different definitions of asthma control, and these differences may affect management and treatment in many patients. Our aim was to describe asthma control patterns according to the Global Initiative for Asthma (GINA) 2023 in patients considered to have uncontrolled asthma as per previous GINA 2010 guidelines. Methods: A total of 1299 patients from the COAS study were analyzed. The COAS study was a cross-sectional multicenter study conducted in routine clinical practice that included patients with uncontrolled asthma according to GINA 2010. These patients were then re-classified using the now updated GINA 2023 asthma control criteria. Results: After applying GINA 2023 control criteria, previously uncontrolled patients were now classified as having controlled asthma in 24.3% of cases and partially controlled asthma in 16.3% of cases. Only 59.4% maintained their previous diagnosis of uncontrolled asthma. ACT in the uncontrolled patients remained similar after re-classification, as did the percentage of active smokers, respiratory allergy, rhinitis, and lung function. Conclusions: Changes in clinical guideline criteria affect the definition of asthma control. When excluding pulmonary function abnormalities in GINA 2023 asthma control criteria, the percentage of controlled patients greatly increased. Keywords: asthma; control; ACT; clinical characteristics; associated factors; GINA Author: Ebymar Arismendi, Paula Ribo, Alberto García, Alfons Torrego, Irina Bobolea, Rocío Casas-Saucedo, Rosa Palomino, César Picado, Rosa Muñoz-Cano and Antonio Valero Creator: LaTeX with hyperref Producer: pdfTeX-1.40.25 CreationDate: Wed Nov 6 07:04:37 2024 CET ModDate: Wed Nov 6 07:06:58 2024 CET Custom Metadata: no Metadata Stream: no Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 8 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 530141 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- YSPQJI+VnURWPalladioL-Bold Type 1 Custom yes yes yes 10 0 OZCFHC+URWPalladioL-Bold Type 1 Custom yes yes yes 16 0 VSQWXE+URWPalladioL-Roma Type 1 Custom yes yes yes 22 0 BCNMLV+URWPalladioL-Ital Type 1 Custom yes yes yes 27 0 DUFXDP+VnURWPalladioL Type 1 Custom yes yes yes 32 0 SKRDUC+CMSY10 Type 1 Builtin yes yes yes 62 0 GOPDEJ+PalatinoLinotype-Bold CID TrueType Identity-H yes yes yes 79 0 GOPDEK+PalatinoLinotype-Roman CID TrueType Identity-H yes yes yes 85 0 GOPDFK+PalatinoLinotype-Italic CID TrueType Identity-H yes yes yes 91 0 GOPDFL+PalatinoLinotype-Italic TrueType WinAnsi yes yes no 97 0 GOPDFM+PalatinoLinotype-Bold TrueType WinAnsi yes yes no 100 0 GOPDFN+PalatinoLinotype-Roman TrueType WinAnsi yes yes no 103 0 GOPDKN+PalatinoLinotype-Roman TrueType MacRoman yes yes no 106 0 WABLSD+SFRM1000 Type 1 Custom yes yes yes 118 0 LWLIVD+EURM10 Type 1 Builtin yes yes yes 130 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-03-21 02:42:52 CET RepresentationInformation: 309293.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-03-20 10:01:27 CET Size: 530141 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 243 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: section.1 Item: Title: Materials and Methods Destination: section.2 Children: Item: Title: Study Design Destination: subsection.2.1 Item: Title: Study Population and Centers Destination: subsection.2.2 Item: Title: Endpoints of the Study Destination: subsection.2.3 Item: Title: Statistical Analysis Destination: subsection.2.4 Item: Title: Results Destination: section.3 Children: Item: Title: Asthma Control According to GINA 2023 Destination: subsection.3.1 Item: Title: Demographic, Clinical, and Asthma Control Characteristics Destination: subsection.3.2 Item: Title: Risk Factors Associated with Poor Asthma Control According to GINA 2023 Destination: subsection.3.3 Item: Title: Discussion Destination: section.4 Item: Title: Conclusions Destination: section.5 Item: Title: References Destination: section.6 Info: Title: Asthma Control According to GINA 2023: Does Changing the Criteria Improve Asthma Control? Author: Ebymar Arismendi, Paula Ribo, Alberto García, Alfons Torrego, Irina Bobolea, Rocío Casas-Saucedo, Rosa Palomino, César Picado, Rosa Muñoz-Cano and Antonio Valero Subject: Background/Objectives: Achieving disease control is the main goal in asthmatic patients in order to prevent future risks and exacerbations. There are several clinical guidelines that set different definitions of asthma control, and these differences may affect management and treatment in many patients. Our aim was to describe asthma control patterns according to the Global Initiative for Asthma (GINA) 2023 in patients considered to have uncontrolled asthma as per previous GINA 2010 guidelines. Methods: A total of 1299 patients from the COAS study were analyzed. The COAS study was a cross-sectional multicenter study conducted in routine clinical practice that included patients with uncontrolled asthma according to GINA 2010. These patients were then re-classified using the now updated GINA 2023 asthma control criteria. Results: After applying GINA 2023 control criteria, previously uncontrolled patients were now classified as having controlled asthma in 24.3% of cases and partially controlled asthma in 16.3% of cases. Only 59.4% maintained their previous diagnosis of uncontrolled asthma. ACT in the uncontrolled patients remained similar after re-classification, as did the percentage of active smokers, respiratory allergy, rhinitis, and lung function. Conclusions: Changes in clinical guideline criteria affect the definition of asthma control. When excluding pulmonary function abnormalities in GINA 2023 asthma control criteria, the percentage of controlled patients greatly increased. 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