62ed0ab2dc6f14353df08d00fc8fd800 309308.pdf 3f4778f9df1b8f6b0bb5e9f6b83c7a8e0161691d 309308.pdf 9958ea9c3e3c25831c99d9dd42a1592c7fa670866cea3f2186c31f0b74e830fc 309308.pdf Title: Development of a prognostic model to predict 90-day mortality in hospitalised cancer patients (PROMISE tool): a prospective observational study Subject: The Lancet Regional Health - Europe, 46 (2024) 101063. doi:10.1016/j.lanepe.2024.101063 Author: Oriol Mirallas Creator: Elsevier Producer: Acrobat Distiller 8.0.0 (Windows) CreationDate: Mon Oct 28 18:46:33 2024 CET ModDate: Mon Oct 28 18:48:18 2024 CET Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 595.276 x 793.701 pts Page rot: 0 File size: 672085 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- EMGNLN+AdvOT20212610.B Type 1C WinAnsi yes yes no 574 0 EMGNLO+AdvOT2867105d.I Type 1C WinAnsi yes yes no 576 0 EMGNLP+AdvstixtSym Type 1C Custom yes yes yes 581 0 EMGNMP+AdvOT3f9da5b7 Type 1C WinAnsi yes yes no 585 0 EMGNNA+AdvOT3f9da5b7+20 Type 1C WinAnsi yes yes no 587 0 EMGNNB+AdvTT0d8bc80f.B Type 1C WinAnsi yes yes no 594 0 EMGNNC+AdvTT0d8bc80f.B+fb Type 1C Custom yes yes yes 599 0 EMGNOD+AdvTT0d8bc80f.B+20 Type 1C WinAnsi yes yes no 590 0 EMGNOE+AdvTTae869a4c Type 1C WinAnsi yes yes no 592 0 EMGNOF+AdvTTae869a4c+20 Type 1C WinAnsi yes yes no 603 0 EMGNOG+AdvTTac2dc932 Type 1C WinAnsi yes yes no 605 0 EMGOBG+AdvTTae869a4c+fb Type 1C Custom yes yes yes 261 0 EMGOCG+AdvOT3f9da5b7+fb Type 1C Custom yes yes yes 262 0 EMGOPD+AdvTTb4077e6a Type 1C WinAnsi yes yes no 276 0 EMGPEC+Advstixtexrm Type 1C Custom yes yes yes 279 0 EMGPED+AdvTTae869a4c+22 Type 1C Custom yes yes no 280 0 EMGPHD+ArialMT CID TrueType Identity-H yes yes yes 288 0 EMGPIE+Verdana-Bold TrueType WinAnsi yes yes no 289 0 EMGPLE+Arial-BoldMT CID TrueType Identity-H yes yes yes 300 0 EMHAAE+Verdana TrueType WinAnsi yes yes no 310 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-03-25 02:41:29 CET RepresentationInformation: 309308.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-03-24 12:54:34 CET Size: 672085 Format: PDF Version: 1.7 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ErrorMessage: Invalid indirect destination - referenced object 'appsec1' cannot be found ID: PDF-HUL-149 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found ID: PDF-HUL-122 Offset: 646996 MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 703 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Development of a prognostic model to predict 90-day mortality in hospitalised cancer patients (PROMISE tool): a prospective ... Destination: titlink1 Children: Item: Title: Introduction Destination: flink1 Item: Title: Methods Destination: flink2 Children: Item: Title: Study design and patient population Destination: slink1 Item: Title: Statistical analysis Destination: slink2 Item: Title: Role of the funding source Destination: slink3 Item: Title: Results Destination: flink3 Children: Item: Title: Patient population Destination: slink4 Item: Title: Hospitalization and survival outcomes Destination: slink5 Item: Title: PROMISE score composition and performance Destination: slink6 Item: Title: Clinical utility of the PROMISE score Destination: slink7 Item: Title: Discussion Destination: flink4 Item: Title: ContributorsOM, RD, and JC designed and wrote the first draft of the report. JAC, MR, AA, SE, TM, AO, CS, EF, AP, EMC, AMM, ... Destination: blink1 Item: Title: Data sharing statementDeidentified patient data from this study can be made available to qualified investigators who provid ... Destination: blink2 Item: Title: Declaration of interests Destination: blink3 Item: Title: Acknowledgements Destination: blink4 Item: Title: Appendix A. Supplementary data Destination: flink5 Item: Title: References Destination: blink5 Info: Title: Development of a prognostic model to predict 90-day mortality in hospitalised cancer patients (PROMISE tool): a prospective observational study Author: Oriol Mirallas Subject: The Lancet Regional Health - Europe, 46 (2024) 101063. doi:10.1016/j.lanepe.2024.101063 Creator: Elsevier Producer: Acrobat Distiller 8.0.0 (Windows) CreationDate: Mon Oct 28 19:16:33 CET 2024 ModDate: Mon Oct 28 19:18:18 CET 2024 ID: 0xefbd455a808a0a036a4365db4f59cc76, 0x13b812d87e32674199260cabc48d7987 Filters: FilterPipeline: FlateDecode Fonts: Type0: Font: BaseFont: EMGPHD+ArialMT Encoding: Identity-H ToUnicode: true Font: BaseFont: EMGPLE+Arial-BoldMT Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: EMGNLO+AdvOT2867105d.I FontSubset: true FirstChar: 44 LastChar: 243 FontDescriptor: FontName: EMGNLO+AdvOT2867105d.I Flags: Serif, Nonsymbolic FontBBox: -104, -239, 791, 833 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EMGNLP+AdvstixtSym FontSubset: true FirstChar: 1 LastChar: 4 FontDescriptor: FontName: EMGNLP+AdvstixtSym Flags: Symbolic FontBBox: -20, -1114, 1135, 822 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EMGOBG+AdvTTae869a4c+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: EMGOBG+AdvTTae869a4c+fb Flags: Symbolic FontBBox: 19, -10, 552, 729 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EMGOCG+AdvOT3f9da5b7+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: EMGOCG+AdvOT3f9da5b7+fb Flags: Symbolic FontBBox: 0, 0, 697, 708 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EMGNMP+AdvOT3f9da5b7 FontSubset: true FirstChar: 37 LastChar: 215 FontDescriptor: FontName: EMGNMP+AdvOT3f9da5b7 Flags: Nonsymbolic FontBBox: -52, -239, 791, 833 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EMGNNA+AdvOT3f9da5b7+20 FontSubset: true FirstChar: 146 LastChar: 150 FontDescriptor: FontName: EMGNNA+AdvOT3f9da5b7+20 Flags: Nonsymbolic FontBBox: -156, -177, 916, 739 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EMGNOD+AdvTT0d8bc80f.B+20 FontSubset: true FirstChar: 150 LastChar: 150 FontDescriptor: FontName: EMGNOD+AdvTT0d8bc80f.B+20 Flags: Nonsymbolic FontBBox: -20, -239, 1197, 729 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EMGNOE+AdvTTae869a4c FontSubset: true FirstChar: 35 LastChar: 241 FontDescriptor: FontName: EMGNOE+AdvTTae869a4c Flags: Serif, Nonsymbolic FontBBox: 0, -250, 927, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EMGNNB+AdvTT0d8bc80f.B FontSubset: true FirstChar: 37 LastChar: 169 FontDescriptor: FontName: EMGNNB+AdvTT0d8bc80f.B Flags: Serif, Nonsymbolic FontBBox: 0, -250, 947, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EMGOPD+AdvTTb4077e6a FontSubset: true FirstChar: 46 LastChar: 108 FontDescriptor: FontName: EMGOPD+AdvTTb4077e6a Flags: Nonsymbolic FontBBox: -104, -239, 822, 833 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EMGNNC+AdvTT0d8bc80f.B+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: EMGNNC+AdvTT0d8bc80f.B+fb Flags: Symbolic FontBBox: 9, -10, 552, 729 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EMGPEC+Advstixtexrm FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: EMGPEC+Advstixtexrm Flags: Symbolic FontBBox: -385, -229, 1041, 729 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EMGPED+AdvTTae869a4c+22 FontSubset: true FirstChar: 21 LastChar: 21 FontDescriptor: FontName: EMGPED+AdvTTae869a4c+22 Flags: Nonsymbolic FontBBox: 19, -10, 520, 729 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: EMGNOF+AdvTTae869a4c+20 FontSubset: true FirstChar: 146 LastChar: 151 FontDescriptor: FontName: EMGNOF+AdvTTae869a4c+20 Flags: Nonsymbolic FontBBox: -20, -239, 1197, 729 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EMGNOG+AdvTTac2dc932 FontSubset: true FirstChar: 40 LastChar: 121 FontDescriptor: FontName: EMGNOG+AdvTTac2dc932 Flags: Serif, Nonsymbolic FontBBox: -166, -250, 1010, 833 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EMGNLN+AdvOT20212610.B FontSubset: true FirstChar: 40 LastChar: 122 FontDescriptor: FontName: EMGNLN+AdvOT20212610.B Flags: Nonsymbolic FontBBox: -52, -239, 833, 833 FontFile3: true Encoding: WinAnsiEncoding TrueType: Font: BaseFont: EMGPIE+Verdana-Bold FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: EMGPIE+Verdana-Bold Flags: Nonsymbolic FontBBox: -550, -303, 1707, 1072 FontFile2: true Encoding: WinAnsiEncoding Font: BaseFont: EMHAAE+Verdana FontSubset: true FirstChar: 32 LastChar: 109 FontDescriptor: FontName: EMHAAE+Verdana Flags: Nonsymbolic FontBBox: -560, -303, 1523, 1051 FontFile2: true Encoding: WinAnsiEncoding CIDFontType2: Font: BaseFont: EMGPLE+Arial-BoldMT CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: EMGPLE+Arial-BoldMT Flags: Symbolic FontBBox: -628, -376, 2000, 1056 FontFile2: true Font: BaseFont: EMGPHD+ArialMT CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: EMGPHD+ArialMT Flags: Symbolic FontBBox: -665, -325, 2000, 1040 FontFile2: true XMP: application/pdf doi:10.1016/j.lanepe.2024.101063 Development of a prognostic model to predict 90-day mortality in hospitalised cancer patients (PROMISE tool): a prospective observational study Oriol Mirallas Berta Martin-Cullell Víctor Navarro Kreina Sharela Vega Jordi Recuero-Borau Diego Gómez-Puerto Daniel López-Valbuena Clara Salva de Torres Laura Andurell Anna Pedrola Roger Berché Fiorella Palmas José María Ucha Guillermo Villacampa Alejandra Rezqallah Judit Sanz-Beltran Rafael Bach Sergio Bueno Cristina Viaplana Gaspar Molina Alberto Hernando-Calvo Juan Aguilar-Company María Roca Eva Muñoz-Couselo Alex Martínez-Martí Ada Alonso Simeon Eremiev Teresa Macarulla Ana Oaknin Cristina Saura Elena Élez Enriqueta Felip Ángeles Peñuelas Rosa Burgos Patricia Gómez Pardo Elena Garralda Josep Tabernero Sònia Serradell Sònia Servitja David Paez Rodrigo Dienstmann Joan Carles Prognostic factors Hospital oncology service 90-day mortality PROMISE tool LASSO method The Lancet Regional Health - Europe, 46 (2024) 101063. doi:10.1016/j.lanepe.2024.101063 The Author(s) journal The Lancet Regional Health - Europe © 2024 The Author(s). Published by Elsevier Ltd. 2666-7762 46 November 2024 101063 101063 10.1016/j.lanepe.2024.101063 https://doi.org/10.1016/j.lanepe.2024.101063 2010-04-23 true 10.1016/j.lanepe.2024.101063 elsevier.com sciencedirect.com VoR 7.0.1 10.1016/j.lanepe.2024.101063 noindex 2010-04-23 true sciencedirect.com elsevier.com Elsevier 2024-10-28T23:16:33+05:30 2024-10-28T23:18:18+05:30 2024-10-28T23:18:18+05:30 True 1 https://www.elsevier.com/tdm/tdmrep-policy.json Acrobat Distiller 8.0.0 (Windows) uuid:59120108-cc07-4528-adb4-5660a2b09b66 uuid:f350aba6-84c3-4b08-bb5a-5be4bad00e7e http://creativecommons.org/licenses/by/4.0/ Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 78, 588, 78, 590 Annotation: Subtype: Link Rect: 79, 589, 83, 595 Destination: 446 Annotation: Subtype: Link Rect: 83, 589, 87, 595 Destination: 446 Annotation: Subtype: Link Rect: 147, 588, 147, 590 Annotation: Subtype: Link Rect: 148, 589, 151, 597 Destination: 446 Annotation: Subtype: Link Rect: 196, 588, 196, 590 Annotation: Subtype: Link Rect: 197, 589, 201, 597 Destination: 446 Annotation: Subtype: Link Rect: 260, 588, 260, 590 Annotation: Subtype: Link Rect: 262, 589, 265, 595 Destination: 446 Annotation: Subtype: Link Rect: 324, 588, 324, 590 Annotation: Subtype: Link Rect: 326, 589, 328, 595 Destination: 446 Annotation: Subtype: Link Rect: 391, 588, 391, 590 Annotation: Subtype: Link Rect: 392, 589, 396, 595 Destination: 446 Annotation: Subtype: Link Rect: 465, 588, 465, 590 Annotation: Subtype: Link Rect: 466, 589, 470, 595 Destination: 446 Annotation: Subtype: Link Rect: 101, 577, 101, 579 Annotation: Subtype: Link Rect: 102, 578, 106, 584 Destination: 446 Annotation: Subtype: Link Rect: 151, 577, 151, 579 Annotation: Subtype: Link Rect: 153, 578, 156, 584 Destination: 446 Annotation: Subtype: Link Rect: 198, 577, 198, 579 Annotation: Subtype: Link Rect: 199, 578, 203, 586 Destination: 446 Annotation: Subtype: Link Rect: 243, 577, 243, 579 Annotation: Subtype: Link Rect: 244, 578, 248, 586 Destination: 446 Annotation: Subtype: Link Rect: 294, 577, 294, 579 Annotation: Subtype: Link Rect: 296, 578, 299, 584 Destination: 446 Annotation: Subtype: Link Rect: 349, 577, 349, 579 Annotation: Subtype: Link Rect: 351, 578, 354, 584 Destination: 446 Annotation: Subtype: Link Rect: 419, 577, 419, 579 Annotation: Subtype: Link Rect: 421, 578, 424, 586 Destination: 446 Annotation: Subtype: Link Rect: 97, 566, 97, 568 Annotation: Subtype: Link Rect: 99, 567, 102, 573 Destination: 446 Annotation: Subtype: Link Rect: 158, 566, 158, 568 Annotation: Subtype: Link Rect: 160, 567, 163, 575 Destination: 446 Annotation: Subtype: Link Rect: 200, 566, 200, 568 Annotation: Subtype: Link Rect: 202, 567, 204, 573 Destination: 446 Annotation: Subtype: Link Rect: 245, 566, 245, 568 Annotation: Subtype: Link Rect: 247, 567, 250, 573 Destination: 446 Annotation: Subtype: Link Rect: 302, 566, 302, 568 Annotation: Subtype: Link Rect: 304, 567, 307, 575 Destination: 446 Annotation: Subtype: Link Rect: 353, 566, 353, 568 Annotation: Subtype: Link Rect: 354, 567, 358, 573 Destination: 446 Annotation: Subtype: Link Rect: 431, 566, 431, 568 Annotation: Subtype: Link Rect: 432, 567, 436, 573 Destination: 446 Annotation: Subtype: Link Rect: 106, 555, 106, 557 Annotation: Subtype: Link Rect: 108, 556, 111, 562 Destination: 446 Annotation: Subtype: Link Rect: 145, 555, 145, 557 Annotation: Subtype: Link Rect: 147, 556, 150, 562 Destination: 446 Annotation: Subtype: Link Rect: 210, 555, 210, 557 Annotation: Subtype: Link Rect: 211, 556, 214, 562 Destination: 446 Annotation: Subtype: Link Rect: 275, 555, 275, 557 Annotation: Subtype: Link Rect: 277, 556, 280, 562 Destination: 446 Annotation: Subtype: Link Rect: 315, 555, 315, 557 Annotation: Subtype: Link Rect: 317, 556, 320, 564 Destination: 446 Annotation: Subtype: Link Rect: 368, 555, 368, 557 Annotation: Subtype: Link Rect: 369, 556, 372, 562 Destination: 446 Annotation: Subtype: Link Rect: 424, 555, 424, 557 Annotation: Subtype: Link Rect: 425, 556, 428, 562 Destination: 446 Annotation: Subtype: Link Rect: 465, 555, 465, 557 Annotation: Subtype: Link Rect: 466, 556, 470, 562 Destination: 446 Annotation: Subtype: Link Rect: 80, 544, 80, 546 Annotation: Subtype: Link Rect: 82, 545, 85, 551 Destination: 446 Annotation: Subtype: Link Rect: 117, 544, 117, 546 Annotation: Subtype: Link Rect: 118, 545, 122, 551 Destination: 446 Annotation: Subtype: Link Rect: 167, 544, 167, 546 Annotation: Subtype: Link Rect: 169, 545, 172, 551 Destination: 446 Annotation: Subtype: Link Rect: 225, 544, 225, 546 Annotation: Subtype: Link Rect: 227, 545, 230, 553 Destination: 446 Annotation: Subtype: Link Rect: 268, 544, 268, 546 Annotation: Subtype: Link Rect: 270, 545, 273, 551 Destination: 446 Annotation: Subtype: Link Rect: 339, 544, 339, 546 Annotation: Subtype: Link Rect: 340, 545, 344, 551 Destination: 446 Annotation: Subtype: Link Rect: 389, 544, 389, 546 Annotation: Subtype: Link Rect: 391, 545, 394, 551 Destination: 446 Annotation: Subtype: Link Rect: 442, 544, 442, 546 Annotation: Subtype: Link Rect: 444, 545, 447, 551 Destination: 446 Annotation: Subtype: Link Rect: 82, 533, 82, 535 Annotation: Subtype: Link Rect: 84, 534, 87, 540 Destination: 446 Annotation: Subtype: Link Rect: 129, 533, 129, 535 Annotation: Subtype: Link Rect: 131, 534, 134, 540 Destination: 446 Annotation: Subtype: Link Rect: 168, 533, 168, 535 Annotation: Subtype: Link Rect: 170, 534, 173, 542 Destination: 446 Annotation: Subtype: Link Rect: 236, 533, 236, 535 Annotation: Subtype: Link Rect: 238, 534, 241, 542 Destination: 446 Annotation: Subtype: Link Rect: 289, 533, 289, 535 Annotation: Subtype: Link Rect: 289, 534, 292, 540 Destination: 446 Annotation: Subtype: Link Rect: 59, 227, 154, 236 Annotation: Subtype: Link Rect: 42, 129, 211, 138 Annotation: Subtype: Link Rect: 96, 61, 163, 68 Annotation: Subtype: Link Rect: 51, 52, 89, 59 Annotation: Subtype: Link Rect: 487, 639, 515, 667 Annotation: Subtype: Link Rect: 487, 378, 540, 385 Annotation: Subtype: Link Rect: 487, 368, 544, 376 Annotation: Subtype: Link Rect: 487, 359, 509, 366 Annotation: Subtype: Link Rect: 39, 12, 96, 19 Page: Label: 2 Annotations: Annotation: Subtype: Link Rect: 322, 311, 324, 317 Destination: 142 Annotation: Subtype: Link Rect: 326, 311, 328, 317 Destination: 142 Annotation: Subtype: Link Rect: 139, 267, 142, 274 Destination: 142 Annotation: Subtype: Link Rect: 143, 267, 146, 274 Destination: 142 Annotation: Subtype: Link Rect: 146, 267, 146, 276 Destination: 142 Annotation: Subtype: Link Rect: 201, 234, 204, 241 Destination: 142 Annotation: Subtype: Link Rect: 321, 212, 328, 219 Destination: 142 Annotation: Subtype: Link Rect: 225, 179, 236, 186 Destination: 142 Annotation: Subtype: Link Rect: 246, 157, 259, 164 Destination: 142 Annotation: Subtype: Link Rect: 454, 313, 459, 319 Destination: 142 Annotation: Subtype: Link Rect: 460, 313, 465, 319 Destination: 142 Annotation: Subtype: Link Rect: 426, 12, 483, 19 Page: Label: 3 Annotations: Annotation: Subtype: Link Rect: 189, 355, 194, 362 Destination: 142 Annotation: Subtype: Link Rect: 195, 355, 200, 362 Destination: 142 Annotation: Subtype: Link Rect: 91, 220, 156, 229 Annotation: Subtype: Link Rect: 390, 640, 395, 647 Destination: 142 Annotation: Subtype: Link Rect: 304, 527, 407, 536 Destination: null Annotation: Subtype: Link Rect: 471, 509, 476, 516 Destination: 142 Annotation: Subtype: Link Rect: 311, 377, 316, 384 Destination: 142 Annotation: Subtype: Link Rect: 419, 220, 476, 229 Destination: null Annotation: Subtype: Link Rect: 266, 209, 309, 218 Destination: null Annotation: Subtype: Link Rect: 471, 125, 476, 132 Destination: 142 Annotation: Subtype: Link Rect: 297, 81, 302, 88 Destination: 142 Annotation: Subtype: Link Rect: 39, 12, 96, 19 Page: Label: 4 Annotations: Annotation: Subtype: Link Rect: 121, 451, 143, 460 Destination: 36 Annotation: Subtype: Link Rect: 121, 374, 148, 383 Destination: 55 Annotation: Subtype: Link Rect: 118, 330, 214, 339 Destination: null Annotation: Subtype: Link Rect: 345, 604, 374, 613 Destination: 55 Annotation: Subtype: Link Rect: 345, 560, 448, 569 Destination: null Annotation: Subtype: Link Rect: 393, 483, 495, 492 Destination: null Annotation: Subtype: Link Rect: 440, 396, 532, 405 Destination: null Annotation: Subtype: Link Rect: 426, 12, 483, 19 Page: Label: 5 Annotations: Annotation: Subtype: Link Rect: 42, 593, 139, 602 Destination: null Annotation: Subtype: Link Rect: 42, 538, 142, 547 Destination: null Annotation: Subtype: Link Rect: 112, 527, 134, 536 Destination: 79 Annotation: Subtype: Link Rect: 203, 462, 226, 471 Destination: 79 Annotation: Subtype: Link Rect: 161, 429, 183, 438 Destination: 98 Annotation: Subtype: Link Rect: 192, 352, 217, 361 Destination: 98 Annotation: Subtype: Link Rect: 86, 286, 178, 295 Destination: null Annotation: Subtype: Link Rect: 144, 188, 164, 197 Destination: 36 Annotation: Subtype: Link Rect: 123, 122, 144, 131 Destination: 98 Annotation: Subtype: Link Rect: 42, 78, 67, 87 Destination: 116 Annotation: Subtype: Link Rect: 402, 100, 424, 109 Destination: 116 Annotation: Subtype: Link Rect: 314, 549, 316, 556 Destination: 55 Annotation: Subtype: Link Rect: 337, 518, 339, 525 Destination: 55 Annotation: Subtype: Link Rect: 322, 384, 324, 391 Destination: 55 Annotation: Subtype: Link Rect: 296, 329, 299, 336 Destination: 55 Annotation: Subtype: Link Rect: 371, 308, 373, 315 Destination: 55 Annotation: Subtype: Link Rect: 356, 244, 358, 251 Destination: 55 Annotation: Subtype: Link Rect: 339, 233, 341, 240 Destination: 55 Annotation: Subtype: Link Rect: 39, 12, 96, 19 Page: Label: 6 Annotations: Annotation: Subtype: Link Rect: 296, 363, 318, 372 Destination: 116 Annotation: Subtype: Link Rect: 121, 319, 218, 328 Destination: null Annotation: Subtype: Link Rect: 300, 308, 328, 317 Annotation: Subtype: Link Rect: 118, 297, 185, 306 Annotation: Subtype: Link Rect: 451, 301, 465, 307 Destination: 216 Annotation: Subtype: Link Rect: 464, 301, 465, 310 Destination: 216 Annotation: Subtype: Link Rect: 426, 12, 483, 19 Page: Label: 7 Annotations: Annotation: Subtype: Link Rect: 157, 175, 170, 182 Destination: 216 Annotation: Subtype: Link Rect: 74, 132, 79, 138 Destination: 216 Annotation: Subtype: Link Rect: 79, 132, 79, 141 Destination: 216 Annotation: Subtype: Link Rect: 176, 88, 181, 94 Destination: 216 Annotation: Subtype: Link Rect: 181, 88, 181, 97 Destination: 216 Annotation: Subtype: Link Rect: 351, 55, 364, 62 Destination: 216 Annotation: Subtype: Link Rect: 364, 55, 364, 64 Destination: 216 Annotation: Subtype: Link Rect: 39, 12, 96, 19 Page: Label: 8 Annotations: Annotation: Subtype: Link Rect: 552, 147, 555, 154 Destination: 142 Annotation: Subtype: Link Rect: 426, 12, 483, 19 Page: Label: 9 Annotations: Annotation: Subtype: Link Rect: 205, 319, 249, 326 Annotation: Subtype: Link Rect: 39, 310, 62, 317 Annotation: Subtype: Link Rect: 227, 292, 249, 299 Annotation: Subtype: Link Rect: 39, 283, 153, 290 Annotation: Subtype: Link Rect: 39, 12, 96, 19 Page: Label: 10 Annotations: Annotation: Subtype: Link Rect: 295, 55, 328, 62 Annotation: Subtype: Link Rect: 118, 46, 217, 53 Annotation: Subtype: Link Rect: 510, 637, 555, 644 Annotation: Subtype: Link Rect: 359, 629, 416, 636 Annotation: Subtype: Link Rect: 359, 597, 461, 604 Annotation: Subtype: Link Rect: 438, 573, 549, 580 Annotation: Subtype: Link Rect: 452, 549, 555, 556 Annotation: Subtype: Link Rect: 359, 541, 377, 548 Annotation: Subtype: Link Rect: 484, 509, 555, 516 Annotation: Subtype: Link Rect: 359, 501, 402, 508 Annotation: Subtype: Link Rect: 484, 477, 555, 484 Annotation: Subtype: Link Rect: 359, 469, 399, 476 Annotation: Subtype: Link Rect: 391, 438, 549, 445 Annotation: Subtype: Link Rect: 386, 414, 555, 421 Annotation: Subtype: Link Rect: 359, 406, 454, 413 Annotation: Subtype: Link Rect: 359, 374, 479, 381 Annotation: Subtype: Link Rect: 374, 350, 494, 357 Annotation: Subtype: Link Rect: 454, 318, 555, 325 Annotation: Subtype: Link Rect: 359, 310, 382, 317 Annotation: Subtype: Link Rect: 420, 278, 521, 285 Annotation: Subtype: Link Rect: 484, 254, 555, 261 Annotation: Subtype: Link Rect: 359, 246, 391, 253 Annotation: Subtype: Link Rect: 522, 222, 555, 229 Annotation: Subtype: Link Rect: 359, 214, 460, 221 Annotation: Subtype: Link Rect: 471, 191, 555, 198 Annotation: Subtype: Link Rect: 359, 183, 396, 190 Annotation: Subtype: Link Rect: 359, 151, 478, 158 Annotation: Subtype: Link Rect: 359, 143, 555, 150 Annotation: Subtype: Link Rect: 359, 135, 464, 142 Annotation: Subtype: Link Rect: 501, 111, 555, 118 Annotation: Subtype: Link Rect: 359, 103, 445, 110 Annotation: Subtype: Link Rect: 533, 79, 555, 86 Annotation: Subtype: Link Rect: 359, 71, 472, 78 Annotation: Subtype: Link Rect: 359, 47, 467, 54 Annotation: Subtype: Link Rect: 426, 12, 483, 19 Page: Label: 11 Annotations: Annotation: Subtype: Link Rect: 195, 645, 249, 652 Annotation: Subtype: Link Rect: 53, 637, 122, 644 Annotation: Subtype: Link Rect: 117, 605, 228, 612 Annotation: Subtype: Link Rect: 216, 581, 249, 588 Annotation: Subtype: Link Rect: 53, 573, 122, 580 Annotation: Subtype: Link Rect: 53, 541, 174, 548 Annotation: Subtype: Link Rect: 124, 509, 226, 516 Annotation: Subtype: Link Rect: 368, 653, 476, 660 Annotation: Subtype: Link Rect: 280, 645, 294, 652 Annotation: Subtype: Link Rect: 362, 613, 476, 620 Annotation: Subtype: Link Rect: 280, 605, 302, 612 Annotation: Subtype: Link Rect: 443, 573, 476, 580 Annotation: Subtype: Link Rect: 280, 565, 391, 572 Annotation: Subtype: Link Rect: 430, 533, 476, 540 Annotation: Subtype: Link Rect: 280, 525, 333, 532 Annotation: Subtype: Link Rect: 454, 501, 476, 508 Annotation: Subtype: Link Rect: 280, 493, 416, 500 Annotation: Subtype: Link Rect: 39, 12, 96, 19 Checksum: 9122522d Type: CRC32 Checksum: 62ed0ab2dc6f14353df08d00fc8fd800 Type: MD5 Checksum: 3f4778f9df1b8f6b0bb5e9f6b83c7a8e0161691d Type: SHA-1 Checksum: 9958ea9c3e3c25831c99d9dd42a1592c7fa670866cea3f2186c31f0b74e830fc Type: SHA-256