03528c93a45cd9b038bd52ad01d6c60b 309317.pdf 1fb705e1d902a844530710e3996df9509414d8af 309317.pdf d055a6520a594df75aa6c2e9a3c5fd25855887aa6fc39eea636b48ac2986746e 309317.pdf Title: Diagnosis and Treatment of Renal ANCA Vasculitis: A Summary of the Consensus Document of the Catalan Group for the Study of Glomerular Diseases (GLOMCAT) Subject: The document provides a comprehensive overview of the diagnosis, monitoring, and treatment of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) with renal involvement, focusing on granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). It outlines the definitions, clinical presentation, histopathological classification, monitoring strategies, induction and maintenance treatments, as well as special considerations for relapsing, refractory, and frail patients with renal AAV. The document was prepared by the Catalan Group for the Study of Glomerular Diseases (GLOMCAT), which comprises nephrologists with extensive experience in the diagnosis and treatment of AAV patients. Several virtual and face-to-face meetings were held for coordination, section assignments, and content discussion. An exhaustive and systematic search of the literature was carried out, which included, among others, the following databases: PubMed, EMBASE, Cochrane Library, Google Scholar, and ClinicalTrials.gov, as well as the abstract books of national and international congresses. Overall, the document provides a comprehensive guide for clinicians managing patients with renal AAV, offering evidence-based recommendations for diagnosis, monitoring, and treatment across various clinical scenarios. Keywords: anti-neutrophil cytoplasmic antibody-associated vasculitis; granulomatosis with polyangiitis; microscopic polyangiitis; eosinophilic granulomatosis with polyangiitis Author: Juliana Bordignon Draibe, Helena Marco, Meritxell Ibernon, Irene Agraz, Carola Arcal, Xoana Barros, Victoria Cabrera, Iara Da Silva, Montserrat Díaz, Xavier Fulladosa, Elena Guillén, Patricia Lescano, Laura Martínez Valenzuela, Eva Márquez, Nadia Martín, Ana Merino, Maru Navarro, Eva Rodríguez, Mª José Soler, Joan Torras, Luís F. Quintana and on behalf of the Catalan Society of Nephrology Creator: LaTeX with hyperref Producer: pdfTeX-1.40.25 CreationDate: Wed Nov 13 02:23:19 2024 CET ModDate: Wed Nov 13 02:26:29 2024 CET Custom Metadata: no Metadata Stream: no Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 17 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 3350516 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- IOJCNK+VnURWPalladioL-Bold Type 1 Custom yes yes yes 10 0 VPFRQT+URWPalladioL-Bold Type 1 Custom yes yes yes 16 0 UTQBEP+URWPalladioL-Roma Type 1 Custom yes yes yes 22 0 CZOUXE+URWPalladioL-Ital Type 1 Custom yes yes yes 27 0 EEWQBJ+VnURWPalladioL Type 1 Custom yes yes yes 32 0 BCDEEE+PalatinoLinotype-Bold TrueType WinAnsi yes yes no 70 0 BCDFEE+PalatinoLinotype-Roman TrueType WinAnsi yes yes no 74 0 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TrueType WinAnsi yes yes no 377 0 BCDFEE+PalatinoLinotype-Roman TrueType WinAnsi yes yes no 381 0 BCDGEE+PalatinoLinotype-Italic TrueType WinAnsi yes yes no 385 0 BCDIEE+PalatinoLinotype-Roman CID TrueType Identity-H yes yes yes 389 0 BCDJEE+PalatinoLinotype-Bold CID TrueType Identity-H yes yes yes 395 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-04-02 02:46:22 CEST RepresentationInformation: 309317.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-04-01 13:51:23 CEST Size: 3350516 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 592 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: section.1 Item: Title: Clinical Presentation and Clinical/Histopathological Diagnosis Destination: section.2 Item: Title: Monitoring Renal AAV After Diagnosis Destination: section.3 Item: Title: Induction and Maintenance Treatment Destination: section.4 Children: Item: Title: Induction Treatment Destination: subsection.4.1 Item: Title: Maintenance Treatment Destination: subsection.4.2 Item: Title: Special Situations Destination: section.5 Children: Item: Title: Relapsing Disease Destination: subsection.5.1 Item: Title: Refractory Disease Destination: subsection.5.2 Item: Title: Treating Frail Patients with Renal AAV Destination: subsection.5.3 Item: Title: References Destination: appendix.A. Info: Title: Diagnosis and Treatment of Renal ANCA Vasculitis: A Summary of the Consensus Document of the Catalan Group for the Study of Glomerular Diseases (GLOMCAT) Author: Juliana Bordignon Draibe, Helena Marco, Meritxell Ibernon, Irene Agraz, Carola Arcal, Xoana Barros, Victoria Cabrera, Iara Da Silva, Montserrat Díaz, Xavier Fulladosa, Elena Guillén, Patricia Lescano, Laura Martínez Valenzuela, Eva Márquez, Nadia Martín, Ana Merino, Maru Navarro, Eva Rodríguez, Mª José Soler, Joan Torras, Luís F. Quintana and on behalf of the Catalan Society of Nephrology Subject: The document provides a comprehensive overview of the diagnosis, monitoring, and treatment of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) with renal involvement, focusing on granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). It outlines the definitions, clinical presentation, histopathological classification, monitoring strategies, induction and maintenance treatments, as well as special considerations for relapsing, refractory, and frail patients with renal AAV. The document was prepared by the Catalan Group for the Study of Glomerular Diseases (GLOMCAT), which comprises nephrologists with extensive experience in the diagnosis and treatment of AAV patients. Several virtual and face-to-face meetings were held for coordination, section assignments, and content discussion. An exhaustive and systematic search of the literature was carried out, which included, among others, the following databases: PubMed, EMBASE, Cochrane Library, Google Scholar, and ClinicalTrials.gov, as well as the abstract books of national and international congresses. Overall, the document provides a comprehensive guide for clinicians managing patients with renal AAV, offering evidence-based recommendations for diagnosis, monitoring, and treatment across various clinical scenarios. 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