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Title:           Defective ribosome assembly impairs leukemia progression in a murine model of acute myeloid leukemia
Subject:         Cell Reports, 43 (2024) . doi:10.1016/j.celrep.2024.114864
Author:          Daniel Sjövall
Creator:         Elsevier
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      Title: Defective ribosome assembly impairs leukemia progression in a murine model of acute myeloid leukemia
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        Title: Introduction
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       Item: 
        Title: Results
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        Children: 
         Item: 
          Title: Immature AML cells exhibit higher ribosome biogenesis rates than mature cells
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         Item: 
          Title: Defective ribosome assembly prolongs survival in leukemia-engrafted mice
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         Item: 
          Title: Severe ribosome assembly defect eradicates most leukemia cells
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         Item: 
          Title: Defective ribosome assembly triggers global transcriptional adaptation in LSCs
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         Item: 
          Title: Adaptation to defective ribosome assembly associates with increased ribosome biogenesis
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         Item: 
          Title: Defective ribosome assembly results in deregulated TF landscape
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         Item: 
          Title: Defective ribosome assembly shows antileukemia efficacy in p53-deficient AML
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       Item: 
        Title: Discussion
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         Item: 
          Title: Limitations of the study
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        Title: Resource availability
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          Title: Data and code availability
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        Title: Acknowledgments
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        Title: Author contributions
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        Title: Declaration of interests
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        Title: STAR★Methods
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            Title: Cell culture
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            Title: Tissue harvest
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            Title: Cell counting
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            Title: Retrovirus production
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            Title: Retroviral transduction
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            Title: Transplantation assays
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            Title: Protein synthesis rate measurement
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            Title: BrdU labeling
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            Title: Flow cytometry
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            Title: Quantitative reverse transcription PCR
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            Title: Polysome profiling
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            Title: Immunoblot
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            Title: CRISPR/Cas9 targeting
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            Title: Mass spectrometry
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              Title: Sample preparation for mass spectrometry analysis
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              Title: Mass spectrometry data acquisition
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              Title: Protein quantification and statistical analysis
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              Title: Single-cell RNA sequencing analysis of the human AML datasets
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              Title: Single-cell RNA sequencing and data analysis of murine MLL-AF9 leukemia
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   Type: CRC32
  Checksum: 0341230475923ff85f3672b0e5bc86ea
   Type: MD5
  Checksum: bef05ec54a062a8ced9f4413b8fcbbf723e08ee8
   Type: SHA-1
  Checksum: 9d2ee2a7ab3ef73cf3dfa440461ee5453994ebccd4134a580a9591265df58c64
   Type: SHA-256