0349a87c678f751c768e40eb23e6f83a 311607.pdf 6c2198e753962e00a3bd0913aa969a0741323101 311607.pdf 0638f2ffc3bad6ec64c13a932be7bb451820782945faa753592e8c7a28763fdd 311607.pdf Creator: Adobe InDesign 18.0 (Windows) Producer: Adobe PDF Library 17.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Tue Oct 8 10:15:19 2024 CEST ModDate: Tue Oct 8 11:41:04 2024 CEST Custom Metadata: yes Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 9 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 1594084 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MinionPro-Regular Type 1C Custom yes no yes 21 0 MinionPro-It Type 1C WinAnsi yes no yes 44 0 MFTZAU+Corbel CID TrueType Identity-H yes yes yes 24 0 Corbel-BoldItalic TrueType WinAnsi yes no yes 155 0 NGOKOS+Wingdings-Regular CID TrueType Identity-H yes yes yes 1814 0 Corbel TrueType WinAnsi yes no yes 23 0 Corbel-Bold TrueType WinAnsi yes no yes 25 0 QTYKJM+Corbel-Bold CID TrueType Identity-H yes yes yes 26 0 Corbel-Bold TrueType WinAnsi yes no yes 1863 0 MinionPro-Bold Type 1C Custom yes no yes 22 0 FMDDBI+STIX-Regular Type 1C WinAnsi yes yes yes 43 0 MinionPro-BoldIt Type 1C WinAnsi yes no yes 98 0 APOZJS+TimesNewRomanPSMT TrueType WinAnsi yes yes yes 198 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-06-26 02:38:49 CEST RepresentationInformation: 311607.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-06-25 14:18:28 CEST Size: 1594084 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Tagged PDF PDFMetadata: Objects: 1894 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en-US Outlines: Item: Title: High increase of Nichols-like clade circulating Treponema pallidum subsp. pallidum in Barcelona from 2021 to 2023 Children: Item: Title: Results Children: Item: Title: Clinical characteristics of patients Item: Title: Amplification success rate and typing of clinical samples based on TP0136, TP0548 and TP0705 Item: Title: Proportion of macrolide and tetracycline resistance-associated genetic determinants in clinical samples Item: Title: Associations between TPA genetic variants and clinical characteristics of patients Item: Title: Discussion Item: Title: Materials and methods Children: Item: Title: Clinical samples collection Item: Title: DNA isolation and treponemal DNA detection Item: Title: Multilocus sequence typing of T. pallidum and detection of genetic resistance-associated determinants to macrolides and tetracyclines Item: Title: Statistical analysis Item: Title: References Info: Creator: Adobe InDesign 18.0 (Windows) Producer: Adobe PDF Library 17.0; 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