875216a29a0d7d6a2795647bfd768b17 000538125.pdf 4af0d86308384e9256a7fef46d6fd16146bc22ee 000538125.pdf b95105f9232c700bcc8c6424dfb6724e91405b8aaa741cf1f4f8fb42189a9f89 000538125.pdf Title: Practical Approaches to the Management of Cardiorenal Disease beyond Congestion Creator: Arbortext Advanced Print Publisher 9.1.510/W Unicode Producer: Acrobat Distiller 7.0 (Windows); modified using iTextSharp 4.1.6 by 1T3XT CreationDate: Fri Apr 19 02:48:40 2024 CEST ModDate: Tue Jul 15 15:00:58 2025 CEST Custom Metadata: no Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 16 Encrypted: no Page size: 595.276 x 793.701 pts Page rot: 0 File size: 1614445 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- OOPGJG+MinionPro-Regular Type 1C WinAnsi yes yes no 649 0 OOPGHG+AdvOT1ef757c0 Type 1C WinAnsi yes yes no 51 0 OOPGGF+AdvOT46dcae81+fb Type 1C Custom yes yes yes 143 0 OOPGGE+AdvOTd0125be5.BI Type 1C WinAnsi yes yes no 50 0 OOPGGD+AdvminionSymbols Type 1C WinAnsi yes yes no 650 0 OOPGFD+AdvOT46dcae81+20 Type 1C WinAnsi yes yes no 166 0 OOPGFC+AdvOT46dcae81 Type 1C WinAnsi yes yes no 48 0 OOPGFB+AdvOT3b30f6db.B Type 1C WinAnsi yes yes no 49 0 OOPGEA+AdvOT3ac66ec5.B Type 1C WinAnsi yes yes no 651 0 UVSQIP+ArialMT TrueType WinAnsi yes yes no 1 0 OOPHDJ+AdvOT310e2d14+22 Type 1C Custom yes yes yes 42 0 OOPHCI+AdvOT310e2d14 Type 1C WinAnsi yes yes no 43 0 OOPHCH+AdvOT1ef757c0+20 Type 1C WinAnsi yes yes no 44 0 OOPHCG+AdvOT1ef757c0+fb Type 1C Custom yes yes yes 45 0 OOPHBF+AdvOT7d6df7ab.I+fb Type 1C Custom yes yes yes 46 0 OOPHBE+AdvOT7d6df7ab.I Type 1C WinAnsi yes yes no 47 0 OOPHNG+AdvTT08640291 Type 1C WinAnsi yes yes no 78 0 OOPLFB+AdvTT2876772e Type 1C WinAnsi yes yes no 144 0 OOPLJE+AdvOT46dcae81+03 Type 1C Custom yes yes yes 164 0 OOPLID+AdvOT3b30f6db.B+fb Type 1C Custom yes yes yes 165 0 OOPLHD+AdvOT1ef757c0+22 Type 1C Custom yes yes no 167 0 OOPLHC+AdvPSSym Type 1C WinAnsi yes yes no 168 0 OOPLND+AdvOT46dcae81+22 Type 1C Custom yes yes no 188 0 OPADCH+AdvOT1ef757c0+03 Type 1C Custom yes yes yes 291 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-07-16 02:41:03 CEST RepresentationInformation: 000538125.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-07-15 15:02:32 CEST Size: 1614445 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 694 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Practical Approaches to the Management of Cardiorenal Disease beyond Congestion Destination: titlink1 Children: Item: Title: Introduction and Magnitude of the Problem Destination: flink1 Children: Item: Title: How Do We Define Cardiorenal Disease? Destination: slink1 Item: Title: Is Cardiorenal Disease a Common Pathology in Clinical Practice? Destination: slink2 Item: Title: Do Cardiorenal Disease Patients Receive Adequate Treatment for Heart Failure? Destination: slink3 Item: Title: Pharmacological Treatment of Heart Failure Destination: flink2 Children: Item: Title: Heart Failure with Reduced Ejection Fraction Destination: slink4 Children: Item: Title: When and How Should We Start Pharmacological Treatment in Patients with Cardiorenal Disease? Destination: sslink1 Item: Title: How to Optimize and Monitor Treatment? Destination: sslink2 Item: Title: When to Stop or Reduce Treatment? Destination: sslink3 Item: Title: What Should Be the Pharmacological Approach in HFrEF Patients on Dialysis? Destination: sslink4 Item: Title: Heart Failure with Preserved Ejection Fraction Destination: slink5 Children: Item: Title: When and How Should We Start Pharmacological Treatment in Patients with Cardiorenal Disease? Destination: sslink5 Item: Title: Anemia Destination: flink3 Children: Item: Title: How Do We Define Anemia and Iron Deficiency (ID) in Patients with Cardiorenal Disease? Destination: slink6 Item: Title: Which Studies Should Be Performed in Patients with Cardiorenal Disease and Anemia? Destination: slink7 Item: Title: When Is Intravenous Iron Indicated? Destination: slink8 Item: Title: When Are Erythropoiesis-Stimulating Agents Indicated? Destination: slink9 Item: Title: Hyperkalaemia Destination: flink4 Children: Item: Title: When Are Potassium Binders Indicated? Destination: slink10 Item: Title: Type 2 Diabetes Mellitus Destination: flink5 Children: Item: Title: What Should Be the Treatment in Patients with Cardiorenal Disease? Destination: slink11 Item: Title: Dyslipidemia Destination: flink6 Children: Item: Title: When Should We Treat Dyslipidemia in Patients with Cardiorenal Disease? Destination: slink12 Item: Title: How Should We Stratify Risk in Patients with Cardiorenal Disease, and What Are the Low-Density Lipoprotein Cholesterol (LDL ... Destination: slink13 Item: Title: How Should We Treat Dyslipidemia in Patients with Cardiorenal Disease? Destination: slink14 Item: Title: Arterial Hypertension Destination: flink7 Children: Item: Title: What Are the Goals of BP and What Should Be the Treatment of Arterial Hypertension in Patients with Cardiorenal Disease? Destination: slink15 Item: Title: Obesity Destination: flink8 Children: Item: Title: Are GLP1 Receptor Agonists Useful in Patients with Cardiorenal Disease and Obesity? Destination: slink16 Item: Title: Atrial Fibrillation Destination: flink9 Children: Item: Title: What Options for Anticoagulation Do We Have in Advanced Kidney Disease? Destination: slink17 Item: Title: Is Left Atrial Appendage Closure a Real Alternative in Patients with Cardiorenal Disease? Destination: slink18 Item: Title: Management of Mineral and Bone Metabolism Disorders Destination: flink10 Children: Item: Title: How Do We Assess the Mineral and Bone Metabolism in Patients with Cardiorenal Disease? Destination: slink19 Item: Title: What Are the Targets and What Drugs Should Be Used? Destination: slink20 Item: Title: Nutrition and Sarcopenia Destination: flink11 Children: Item: Title: Which Tools Do We Have to Evaluate Nutritional Status in Patients with Cardiorenal Disease? Destination: slink21 Item: Title: How Do We Treat Malnutrition and Sarcopenia? Destination: slink22 Item: Title: Prevention of Contrast-Associated Acute Kidney Injury Destination: flink12 Children: Item: Title: When Should Prophylaxis Be Given? Destination: slink23 Item: Title: What Is the Best Strategy to Avoid CA-AKI in Patients with Cardiorenal Disease? Destination: slink24 Item: Title: Conclusions Destination: flink13 Item: Title: Conflict of Interest Statement Destination: flink14 Item: Title: Funding Sources Destination: flink15 Item: Title: Author Contributions Destination: flink16 Item: Title: References Destination: rlink1 Info: Title: Practical Approaches to the Management of Cardiorenal Disease beyond Congestion Creator: Arbortext Advanced Print Publisher 9.1.510/W Unicode Producer: Acrobat Distiller 7.0 (Windows); modified using iTextSharp 4.1.6 by 1T3XT CreationDate: Fri Apr 19 03:18:40 CEST 2024 ModDate: Tue Jul 15 15:00:58 CEST 2025 ID: 0xcfd22b0ab501c9414d4b6b8bfd21de94, 0x5adb005061849154564a990e099b6e10 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 819 ImageHeight: 35 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 431 ImageHeight: 283 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: OPADCH+AdvOT1ef757c0+03 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: OPADCH+AdvOT1ef757c0+03 Flags: Symbolic FontBBox: -125, -270, 854, 791 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: OOPLJE+AdvOT46dcae81+03 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: OOPLJE+AdvOT46dcae81+03 Flags: Symbolic FontBBox: -31, -208, 739, 802 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: OOPLID+AdvOT3b30f6db.B+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: OOPLID+AdvOT3b30f6db.B+fb Flags: Symbolic FontBBox: 0, 0, 833, 718 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: OOPGFD+AdvOT46dcae81+20 FontSubset: true FirstChar: 147 LastChar: 150 FontDescriptor: FontName: OOPGFD+AdvOT46dcae81+20 Flags: Nonsymbolic FontBBox: -156, -197, 1125, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OOPLHD+AdvOT1ef757c0+22 FontSubset: true FirstChar: 21 LastChar: 21 FontDescriptor: FontName: OOPLHD+AdvOT1ef757c0+22 Flags: Nonsymbolic FontBBox: -135, -166, 697, 916 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: OOPLHC+AdvPSSym FontSubset: true FirstChar: 129 LastChar: 129 FontDescriptor: FontName: OOPLHC+AdvPSSym Flags: Nonsymbolic FontBBox: -177, -291, 1083, 1010 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OOPGJG+MinionPro-Regular FontSubset: true FirstChar: 32 LastChar: 64 FontDescriptor: FontName: OOPGJG+MinionPro-Regular Flags: Nonsymbolic FontBBox: -290, -360, 1684, 989 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OOPGGD+AdvminionSymbols FontSubset: true FirstChar: 183 LastChar: 183 FontDescriptor: FontName: OOPGGD+AdvminionSymbols Flags: Nonsymbolic FontBBox: -135, -947, 1333, 895 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OOPHDJ+AdvOT310e2d14+22 FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: OOPHDJ+AdvOT310e2d14+22 Flags: Symbolic FontBBox: -135, -385, 1333, 895 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: OOPGEA+AdvOT3ac66ec5.B FontSubset: true FirstChar: 67 LastChar: 114 FontDescriptor: FontName: OOPGEA+AdvOT3ac66ec5.B Flags: Nonsymbolic FontBBox: -72, -239, 1000, 947 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OOPHCI+AdvOT310e2d14 FontSubset: true FirstChar: 60 LastChar: 62 FontDescriptor: FontName: OOPHCI+AdvOT310e2d14 Flags: Nonsymbolic FontBBox: -20, -427, 1541, 1062 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OOPHCH+AdvOT1ef757c0+20 FontSubset: true FirstChar: 146 LastChar: 150 FontDescriptor: FontName: OOPHCH+AdvOT1ef757c0+20 Flags: Nonsymbolic FontBBox: -135, -218, 1010, 833 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OOPHCG+AdvOT1ef757c0+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: OOPHCG+AdvOT1ef757c0+fb Flags: Symbolic FontBBox: 0, -10, 781, 708 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: OOPHBF+AdvOT7d6df7ab.I+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: OOPHBF+AdvOT7d6df7ab.I+fb Flags: Symbolic FontBBox: -156, -250, 802, 708 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: OOPHNG+AdvTT08640291 FontSubset: true FirstChar: 42 LastChar: 42 FontDescriptor: FontName: OOPHNG+AdvTT08640291 Flags: Nonsymbolic FontBBox: 0, -208, 916, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OOPGGF+AdvOT46dcae81+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: OOPGGF+AdvOT46dcae81+fb Flags: Symbolic FontBBox: 0, 0, 739, 718 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: OOPHBE+AdvOT7d6df7ab.I FontSubset: true FirstChar: 40 LastChar: 121 FontDescriptor: FontName: OOPHBE+AdvOT7d6df7ab.I Flags: Serif, Nonsymbolic FontBBox: -135, -250, 1000, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OOPGFC+AdvOT46dcae81 FontSubset: true FirstChar: 37 LastChar: 250 FontDescriptor: FontName: OOPGFC+AdvOT46dcae81 Flags: Nonsymbolic FontBBox: -41, -250, 833, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OOPLFB+AdvTT2876772e FontSubset: true FirstChar: 45 LastChar: 45 FontDescriptor: FontName: OOPLFB+AdvTT2876772e Flags: Nonsymbolic FontBBox: -41, -208, 979, 916 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OOPGFB+AdvOT3b30f6db.B FontSubset: true FirstChar: 45 LastChar: 121 FontDescriptor: FontName: OOPGFB+AdvOT3b30f6db.B Flags: Nonsymbolic FontBBox: -31, -250, 875, 895 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OOPGGE+AdvOTd0125be5.BI FontSubset: true FirstChar: 58 LastChar: 121 FontDescriptor: FontName: OOPGGE+AdvOTd0125be5.BI Flags: Nonsymbolic FontBBox: -93, -250, 927, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OOPGHG+AdvOT1ef757c0 FontSubset: true FirstChar: 37 LastChar: 252 FontDescriptor: FontName: OOPGHG+AdvOT1ef757c0 Flags: Serif, Nonsymbolic FontBBox: -20, -250, 947, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: OOPLND+AdvOT46dcae81+22 FontSubset: true FirstChar: 21 LastChar: 21 FontDescriptor: FontName: OOPLND+AdvOT46dcae81+22 Flags: Nonsymbolic FontBBox: -156, -145, 687, 822 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true TrueType: Font: BaseFont: UVSQIP+ArialMT FontSubset: true FirstChar: 32 LastChar: 242 FontDescriptor: FontName: UVSQIP+ArialMT Flags: Nonsymbolic FontBBox: -664, -324, 2000, 1039 FontFile2: true Encoding: WinAnsiEncoding XMP: Acrobat Distiller 7.0 (Windows); modified using iTextSharp 4.1.6 by 1T3XT 2024-04-19T06:18:40+05:30 2025-07-15T13:00:58+00:00 Arbortext Advanced Print Publisher 9.1.510/W Unicode application/pdf Practical Approaches to the Management of Cardiorenal Disease beyond Congestion uuid:c0aad8ec-2e8b-4261-a44b-a7847f902bac uuid:86a4de6e-a058-42d9-b94b-23624d92f905 Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 43, 732, 123, 746 Annotation: Subtype: Link Rect: 43, 715, 103, 729 Annotation: Subtype: Link Rect: 234, 698, 305, 706 Annotation: Subtype: Link Rect: 43, 60, 97, 67 Annotation: Subtype: Link Rect: 43, 51, 103, 58 Annotation: Subtype: Link Rect: 263, 29, 291, 34 Annotation: Subtype: Link Rect: 130, 22, 226, 28 Page: Label: 2 Annotations: Annotation: Subtype: Link Rect: 47, 433, 52, 444 Destination: 248 Annotation: Subtype: Link Rect: 242, 421, 269, 432 Destination: 73 Annotation: Subtype: Link Rect: 225, 371, 230, 382 Destination: 248 Annotation: Subtype: Link Rect: 76, 296, 81, 307 Destination: 248 Annotation: Subtype: Link Rect: 212, 209, 217, 220 Destination: 248 Annotation: Subtype: Link Rect: 223, 209, 228, 220 Destination: 248 Annotation: Subtype: Link Rect: 280, 146, 285, 157 Destination: 248 Annotation: Subtype: Link Rect: 357, 719, 362, 730 Destination: 248 Annotation: Subtype: Link Rect: 515, 682, 526, 693 Destination: 248 Annotation: Subtype: Link Rect: 425, 570, 435, 581 Destination: 248 Annotation: Subtype: Link Rect: 414, 520, 419, 531 Destination: 248 Annotation: Subtype: Link Rect: 428, 520, 438, 531 Destination: 248 Annotation: Subtype: Link Rect: 404, 483, 415, 494 Destination: 248 Annotation: Subtype: Link Rect: 487, 333, 497, 344 Destination: 248 Annotation: Subtype: Link Rect: 425, 271, 435, 282 Destination: 248 Annotation: Subtype: Link Rect: 338, 184, 347, 195 Destination: 248 Annotation: Subtype: Link Rect: 424, 97, 435, 107 Destination: 248 Annotation: Subtype: Link Rect: 441, 97, 451, 107 Destination: 248 Annotation: Subtype: Link Rect: 463, 97, 488, 107 Destination: 99 Annotation: Subtype: Link Rect: 148, 49, 211, 57 Page: Label: 3 Annotations: Annotation: Subtype: Link Rect: 106, 395, 116, 406 Destination: 248 Annotation: Subtype: Link Rect: 122, 395, 131, 406 Destination: 248 Annotation: Subtype: Link Rect: 249, 346, 259, 357 Destination: 248 Annotation: Subtype: Link Rect: 233, 283, 243, 294 Destination: 248 Annotation: Subtype: Link Rect: 248, 283, 259, 294 Destination: 248 Annotation: Subtype: Link Rect: 238, 258, 248, 269 Destination: 248 Annotation: Subtype: Link Rect: 47, 221, 57, 232 Destination: 248 Annotation: Subtype: Link Rect: 69, 221, 93, 232 Destination: 112 Annotation: Subtype: Link Rect: 47, 159, 57, 170 Destination: 289 Annotation: Subtype: Link Rect: 140, 97, 150, 108 Destination: 289 Annotation: Subtype: Link Rect: 161, 97, 186, 108 Destination: 112 Annotation: Subtype: Link Rect: 477, 346, 487, 357 Destination: 248 Annotation: Subtype: Link Rect: 522, 321, 545, 332 Destination: 99 Annotation: Subtype: Link Rect: 535, 159, 545, 170 Destination: 289 Annotation: Subtype: Link Rect: 520, 109, 530, 120 Destination: 248 Annotation: Subtype: Link Rect: 535, 109, 545, 120 Destination: 289 Annotation: Subtype: Link Rect: 322, 49, 386, 57 Page: Label: 4 Annotations: Annotation: Subtype: Link Rect: 167, 258, 178, 269 Destination: 289 Annotation: Subtype: Link Rect: 459, 196, 469, 207 Destination: 289 Annotation: Subtype: Link Rect: 357, 146, 367, 157 Destination: 289 Annotation: Subtype: Link Rect: 536, 97, 546, 107 Destination: 289 Annotation: Subtype: Link Rect: 148, 49, 211, 57 Page: Label: 5 Annotations: Annotation: Subtype: Link Rect: 156, 399, 165, 410 Destination: 289 Annotation: Subtype: Link Rect: 139, 361, 149, 372 Destination: 248 Annotation: Subtype: Link Rect: 155, 361, 165, 372 Destination: 289 Annotation: Subtype: Link Rect: 276, 336, 285, 347 Destination: 289 Annotation: Subtype: Link Rect: 275, 185, 285, 196 Destination: 248 Annotation: Subtype: Link Rect: 177, 146, 188, 157 Destination: 289 Annotation: Subtype: Link Rect: 260, 97, 270, 107 Destination: 289 Annotation: Subtype: Link Rect: 276, 97, 285, 107 Destination: 289 Annotation: Subtype: Link Rect: 343, 644, 352, 655 Destination: 289 Annotation: Subtype: Link Rect: 339, 545, 349, 556 Destination: 289 Annotation: Subtype: Link Rect: 467, 520, 477, 531 Destination: 289 Annotation: Subtype: Link Rect: 398, 458, 409, 469 Destination: 289 Annotation: Subtype: Link Rect: 377, 420, 411, 431 Destination: 141 Annotation: Subtype: Link Rect: 345, 358, 355, 369 Destination: 248 Annotation: Subtype: Link Rect: 361, 358, 371, 369 Destination: 289 Annotation: Subtype: Link Rect: 386, 283, 396, 294 Destination: 248 Annotation: Subtype: Link Rect: 402, 283, 412, 294 Destination: 289 Annotation: Subtype: Link Rect: 423, 283, 454, 294 Destination: 162 Annotation: Subtype: Link Rect: 323, 246, 333, 257 Destination: 289 Annotation: Subtype: Link Rect: 479, 159, 489, 170 Destination: 289 Annotation: Subtype: Link Rect: 322, 49, 386, 57 Page: Label: 6 Annotations: Annotation: Subtype: Link Rect: 46, 448, 56, 458 Destination: 289 Annotation: Subtype: Link Rect: 65, 448, 95, 458 Destination: 162 Annotation: Subtype: Link Rect: 276, 286, 286, 297 Destination: 289 Annotation: Subtype: Link Rect: 221, 223, 231, 234 Destination: 289 Annotation: Subtype: Link Rect: 236, 223, 246, 234 Destination: 289 Annotation: Subtype: Link Rect: 256, 223, 286, 234 Destination: 186 Annotation: Subtype: Link Rect: 278, 111, 289, 122 Destination: 248 Annotation: Subtype: Link Rect: 43, 99, 54, 110 Destination: 289 Annotation: Subtype: Link Rect: 487, 423, 498, 434 Destination: 289 Annotation: Subtype: Link Rect: 418, 323, 429, 334 Destination: 289 Annotation: Subtype: Link Rect: 433, 323, 444, 334 Destination: 289 Annotation: Subtype: Link Rect: 491, 248, 501, 259 Destination: 289 Annotation: Subtype: Link Rect: 512, 248, 545, 259 Destination: 200 Annotation: Subtype: Link Rect: 148, 49, 211, 57 Page: Label: 7 Annotations: Annotation: Subtype: Link Rect: 135, 258, 145, 269 Destination: 289 Annotation: Subtype: Link Rect: 217, 170, 227, 181 Destination: 289 Annotation: Subtype: Link Rect: 303, 181, 334, 192 Destination: 205 Annotation: Subtype: Link Rect: 353, 156, 363, 167 Destination: 289 Annotation: Subtype: Link Rect: 369, 156, 379, 167 Destination: 289 Annotation: Subtype: Link Rect: 482, 131, 491, 142 Destination: 289 Annotation: Subtype: Link Rect: 535, 106, 545, 117 Destination: 347 Annotation: Subtype: Link Rect: 322, 49, 386, 57 Page: Label: 8 Annotations: Annotation: Subtype: Link Rect: 131, 148, 141, 159 Destination: 289 Annotation: Subtype: Link Rect: 229, 98, 239, 109 Destination: 289 Annotation: Subtype: Link Rect: 487, 359, 497, 370 Destination: 289 Annotation: Subtype: Link Rect: 394, 247, 404, 258 Destination: 347 Annotation: Subtype: Link Rect: 411, 247, 421, 258 Destination: 347 Annotation: Subtype: Link Rect: 484, 198, 494, 208 Destination: 347 Annotation: Subtype: Link Rect: 435, 123, 445, 134 Destination: 289 Annotation: Subtype: Link Rect: 148, 49, 211, 57 Page: Label: 9 Annotations: Annotation: Subtype: Link Rect: 514, 112, 525, 123 Destination: 347 Annotation: Subtype: Link Rect: 322, 49, 386, 57 Page: Label: 10 Annotations: Annotation: Subtype: Link Rect: 106, 396, 116, 407 Destination: 289 Annotation: Subtype: Link Rect: 257, 371, 267, 382 Destination: 347 Annotation: Subtype: Link Rect: 92, 334, 102, 345 Destination: 347 Annotation: Subtype: Link Rect: 150, 122, 160, 133 Destination: 347 Annotation: Subtype: Link Rect: 376, 396, 400, 407 Destination: 215 Annotation: Subtype: Link Rect: 367, 259, 378, 270 Destination: 347 Annotation: Subtype: Link Rect: 148, 49, 211, 57 Page: Label: 11 Annotations: Annotation: Subtype: Link Rect: 119, 361, 130, 372 Destination: 347 Annotation: Subtype: Link Rect: 47, 237, 75, 248 Destination: 228 Annotation: Subtype: Link Rect: 521, 411, 547, 422 Destination: 228 Annotation: Subtype: Link Rect: 307, 399, 317, 410 Destination: 347 Annotation: Subtype: Link Rect: 322, 49, 386, 57 Page: Label: 12 Annotations: Annotation: Subtype: Link Rect: 47, 346, 57, 357 Destination: 347 Annotation: Subtype: Link Rect: 245, 296, 255, 307 Destination: 347 Annotation: Subtype: Link Rect: 384, 209, 394, 220 Destination: 347 Annotation: Subtype: Link Rect: 440, 184, 451, 195 Destination: 347 Annotation: Subtype: Link Rect: 416, 109, 426, 120 Destination: 347 Annotation: Subtype: Link Rect: 148, 49, 211, 57 Page: Label: 13 Annotations: Annotation: Subtype: Link Rect: 106, 389, 140, 400 Destination: 242 Annotation: Subtype: Link Rect: 86, 227, 97, 238 Destination: 347 Annotation: Subtype: Link Rect: 322, 49, 386, 57 Page: Label: 14 Annotations: Annotation: Subtype: Link Rect: 111, 531, 205, 539 Annotation: Subtype: Link Rect: 57, 521, 81, 530 Annotation: Subtype: Link Rect: 57, 465, 141, 473 Annotation: Subtype: Link Rect: 123, 408, 205, 416 Annotation: Subtype: Link Rect: 57, 398, 81, 407 Annotation: Subtype: Link Rect: 72, 332, 178, 340 Annotation: Subtype: Link Rect: 100, 285, 165, 293 Annotation: Subtype: Link Rect: 57, 228, 164, 236 Annotation: Subtype: Link Rect: 157, 171, 205, 179 Annotation: Subtype: Link Rect: 57, 162, 126, 170 Annotation: Subtype: Link Rect: 195, 114, 205, 123 Annotation: Subtype: Link Rect: 57, 105, 120, 113 Annotation: Subtype: Link Rect: 368, 512, 378, 520 Annotation: Subtype: Link Rect: 230, 502, 303, 511 Annotation: Subtype: Link Rect: 278, 446, 373, 454 Annotation: Subtype: Link Rect: 368, 398, 378, 407 Annotation: Subtype: Link Rect: 230, 389, 308, 397 Annotation: Subtype: Link Rect: 274, 342, 359, 350 Annotation: Subtype: Link Rect: 245, 294, 329, 302 Annotation: Subtype: Link Rect: 317, 237, 378, 246 Annotation: Subtype: Link Rect: 230, 228, 258, 236 Annotation: Subtype: Link Rect: 336, 162, 378, 170 Annotation: Subtype: Link Rect: 230, 152, 246, 160 Annotation: Subtype: Link Rect: 282, 105, 366, 113 Annotation: Subtype: Link Rect: 523, 521, 551, 530 Annotation: Subtype: Link Rect: 404, 512, 515, 520 Annotation: Subtype: Link Rect: 501, 465, 551, 473 Annotation: Subtype: Link Rect: 404, 455, 441, 463 Annotation: Subtype: Link Rect: 493, 379, 551, 388 Annotation: Subtype: Link Rect: 404, 370, 443, 378 Annotation: Subtype: Link Rect: 501, 304, 551, 312 Annotation: Subtype: Link Rect: 404, 294, 426, 302 Annotation: Subtype: Link Rect: 487, 237, 551, 246 Annotation: Subtype: Link Rect: 404, 228, 425, 236 Annotation: Subtype: Link Rect: 404, 162, 511, 170 Annotation: Subtype: Link Rect: 521, 114, 551, 123 Annotation: Subtype: Link Rect: 404, 105, 464, 113 Annotation: Subtype: Link Rect: 148, 49, 211, 57 Page: Label: 15 Annotations: Annotation: Subtype: Link Rect: 176, 684, 205, 692 Annotation: Subtype: Link Rect: 57, 675, 113, 683 Annotation: Subtype: Link Rect: 104, 599, 162, 607 Annotation: Subtype: Link Rect: 144, 561, 205, 569 Annotation: Subtype: Link Rect: 57, 552, 80, 560 Annotation: Subtype: Link Rect: 176, 495, 205, 503 Annotation: Subtype: Link Rect: 57, 485, 168, 493 Annotation: Subtype: Link Rect: 195, 428, 205, 437 Annotation: Subtype: Link Rect: 57, 419, 133, 427 Annotation: Subtype: Link Rect: 57, 372, 154, 380 Annotation: Subtype: Link Rect: 155, 315, 205, 323 Annotation: Subtype: Link Rect: 57, 305, 113, 314 Annotation: Subtype: Link Rect: 118, 258, 201, 266 Annotation: Subtype: Link Rect: 160, 211, 205, 219 Annotation: Subtype: Link Rect: 57, 201, 77, 210 Annotation: Subtype: Link Rect: 119, 154, 198, 162 Annotation: Subtype: Link Rect: 278, 703, 363, 711 Annotation: Subtype: Link Rect: 317, 637, 378, 645 Annotation: Subtype: Link Rect: 230, 627, 258, 635 Annotation: Subtype: Link Rect: 245, 589, 330, 597 Annotation: Subtype: Link Rect: 295, 542, 368, 550 Annotation: Subtype: Link Rect: 314, 495, 378, 503 Annotation: Subtype: Link Rect: 230, 485, 252, 493 Annotation: Subtype: Link Rect: 350, 419, 378, 427 Annotation: Subtype: Link Rect: 230, 409, 281, 418 Annotation: Subtype: Link Rect: 317, 353, 378, 361 Annotation: Subtype: Link Rect: 230, 343, 258, 351 Annotation: Subtype: Link Rect: 245, 286, 309, 295 Annotation: Subtype: Link Rect: 350, 248, 378, 257 Annotation: Subtype: Link Rect: 230, 239, 286, 247 Annotation: Subtype: Link Rect: 245, 220, 318, 228 Annotation: Subtype: Link Rect: 368, 154, 378, 162 Annotation: Subtype: Link Rect: 230, 144, 307, 153 Annotation: Subtype: Link Rect: 451, 712, 538, 721 Annotation: Subtype: Link Rect: 523, 665, 551, 673 Annotation: Subtype: Link Rect: 404, 655, 460, 664 Annotation: Subtype: Link Rect: 419, 608, 503, 616 Annotation: Subtype: Link Rect: 541, 561, 551, 569 Annotation: Subtype: Link Rect: 404, 551, 482, 560 Annotation: Subtype: Link Rect: 523, 485, 551, 493 Annotation: Subtype: Link Rect: 404, 476, 482, 484 Annotation: Subtype: Link Rect: 541, 428, 551, 437 Annotation: Subtype: Link Rect: 404, 419, 478, 427 Annotation: Subtype: Link Rect: 418, 372, 499, 380 Annotation: Subtype: Link Rect: 419, 296, 480, 304 Annotation: Subtype: Link Rect: 453, 248, 535, 257 Annotation: Subtype: Link Rect: 449, 201, 529, 209 Annotation: Subtype: Link Rect: 454, 154, 537, 162 Annotation: Subtype: Link Rect: 418, 107, 497, 115 Annotation: Subtype: Link Rect: 322, 49, 386, 57 Page: Label: 16 Annotations: Annotation: Subtype: Link Rect: 127, 665, 205, 673 Annotation: Subtype: Link Rect: 57, 656, 78, 664 Annotation: Subtype: Link Rect: 195, 570, 205, 579 Annotation: Subtype: Link Rect: 57, 561, 147, 569 Annotation: Subtype: Link Rect: 195, 476, 205, 484 Annotation: Subtype: Link Rect: 57, 466, 155, 475 Annotation: Subtype: Link Rect: 72, 410, 172, 418 Annotation: Subtype: Link Rect: 107, 362, 189, 370 Annotation: Subtype: Link Rect: 349, 684, 378, 692 Annotation: Subtype: Link Rect: 230, 675, 288, 683 Annotation: Subtype: Link Rect: 245, 627, 329, 635 Annotation: Subtype: Link Rect: 278, 570, 367, 579 Annotation: Subtype: Link Rect: 368, 523, 378, 531 Annotation: Subtype: Link Rect: 230, 514, 316, 522 Annotation: Subtype: Link Rect: 313, 457, 378, 465 Annotation: Subtype: Link Rect: 230, 447, 258, 456 Annotation: Subtype: Link Rect: 323, 372, 378, 380 Annotation: Subtype: Link Rect: 230, 362, 269, 370 Annotation: Subtype: Link Rect: 523, 684, 551, 692 Annotation: Subtype: Link Rect: 404, 675, 447, 683 Annotation: Subtype: Link Rect: 541, 618, 551, 626 Annotation: Subtype: Link Rect: 404, 608, 492, 616 Annotation: Subtype: Link Rect: 541, 552, 551, 560 Annotation: Subtype: Link Rect: 404, 542, 508, 550 Annotation: Subtype: Link Rect: 419, 495, 499, 503 Annotation: Subtype: Link Rect: 541, 438, 551, 446 Annotation: Subtype: Link Rect: 404, 428, 479, 437 Annotation: Subtype: Link Rect: 436, 362, 521, 370 Annotation: Subtype: Link Rect: 148, 49, 211, 57 Checksum: f68c09e2 Type: CRC32 Checksum: 875216a29a0d7d6a2795647bfd768b17 Type: MD5 Checksum: 4af0d86308384e9256a7fef46d6fd16146bc22ee Type: SHA-1 Checksum: b95105f9232c700bcc8c6424dfb6724e91405b8aaa741cf1f4f8fb42189a9f89 Type: SHA-256