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Title: ACTIV trials: Lessons learned in trial design in the setting of an emergent pandemic Destination: temp:book:TitleC_1 Children: Item: Title: Introduction Destination: temp:book:Section1_2 Children: Item: Title: Protocol design in the context of the unknown Destination: temp:book:Section1_3 Item: Title: ACTIV master protocol central design principles Destination: temp:book:Section1_4 Item: Title: Sample-size calculation and power Destination: temp:book:Section1_5 Item: Title: Flexible inclusion/exclusion (eligibility) criteria Destination: temp:book:Section1_6 Item: Title: Outcomes measure and optimal endpoints Destination: temp:book:Section1_7 Item: Title: Industry partnership Destination: temp:book:Section1_8 Item: Title: Definition and simplicity in trial governance structure Destination: temp:book:Section1_9 Item: Title: Regulatory Destination: temp:book:Section1_10 Item: Title: Assembling networks to support platform trial design and conduct Destination: temp:book:Section1_11 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