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Title:           CSF proteomics identifies early changes in autosomal dominant Alzheimer's disease
Subject:         Cell, 187 (2024) 6309-6341. doi:10.1016/j.cell.2024.08.049
Author:          Yuanyuan Shen
Creator:         Elsevier
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      Title: CSF proteomics identifies early changes in autosomal dominant Alzheimer’s disease
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        Title: Introduction
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       Item: 
        Title: Results
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          Title: Study design
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          Title: Significantly different pseudo-trajectory protein identification in CSF samples
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         Item: 
          Title: Comparison of significantly altered proteins in ADAD and sAD
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         Item: 
          Title: Earliest CSF proteomic changes
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         Item: 
          Title: Plasma-specific analyses find low overlap with CSF
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         Item: 
          Title: CSF-brain comparison identified complex protein dynamics across tissues
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         Item: 
          Title: CSF-dysregulated proteins capture pathways implicated in neuronal death and inflammation
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         Item: 
          Title: Co-expression network analysis identified modules that capture the chronological progression in ADAD
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         Item: 
          Title: Predictive models of ADAD
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        Title: Discussion
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         Item: 
          Title: Limitations of the study
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        Title: Resource availability
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          Title: Lead contact
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          Title: Data and code availability
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        Title: Consortia
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        Title: Acknowledgments
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        Title: Author contributions
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        Title: Declaration of interests
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        Title: References
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        Title: STAR★Methods
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          Title: Key resources table
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          Title: Experimental model and study participant details
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           Item: 
            Title: ADAD and sporadic AD cohorts
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            Title: ADAD cohort
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            Title: Sporadic late-onset Alzheimer's disease proteomics data cohorts
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          Title: Method details
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            Title: Clinical assessment and EYO in ADAD
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            Title: CSF proteomic data collection, processing, and quality control
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            Title: Plasma proteomics data collection, processing, and QC
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            Title: ATN classification
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          Title: Quantification and statistical analysis
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           Item: 
            Title: Cohorts demographics
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            Title: Differential pseudo-trajectory analysis
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           Item: 
            Title: Pseudo-trajectory intersections in ADAD
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           Item: 
            Title: ADAD protein change and sAD protein change analysis in ADAD and sAD
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           Item: 
            Title: Proteomic comparison across studies
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            Title: Predictive models
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            Title: Pathway analyses
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            Title: Cell type enrichment
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            Title: Co-expression network analyses
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          Title: Additional resources
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            Title: Data visualization
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           Item: 
            Title: Web browser for navigating results
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