7d99ace290591f2f337b170fe5ba88a0 MISO_a2024v10p001334.pdf 95785a7f64663637083069685d8f510f4ee1e689 MISO_a2024v10p001334.pdf 0503f1bfdf421a648215b4707765750887938454cdf6c70640692d31d2ff50db MISO_a2024v10p001334.pdf Creator: Adobe InDesign CS6 (Windows) Producer: Adobe PDF Library 10.0.1 CreationDate: Thu Dec 19 11:24:38 2024 CET ModDate: Thu Dec 19 11:24:40 2024 CET Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 14 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 559845 bytes Optimized: yes PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- ZHIYPU+DINNextLTPro-Light Type 1C Custom yes yes yes 301 0 SURIVI+DINNextLTPro-Italic Type 1C Custom yes yes yes 302 0 SURIVI+DINNextLTPro-Regular Type 1C Custom yes yes yes 303 0 OQKFWQ+DINNextLTPro-Bold Type 1C Custom yes yes yes 318 0 LHFNBW+DINNextLTPro-LightItalic Type 1C WinAnsi yes yes yes 319 0 LHFNBW+DINNextLTPro-Medium Type 1C WinAnsi yes yes yes 327 0 OQKFWQ+DINNextLTPro-Bold Type 1C WinAnsi yes yes no 346 0 OQKFWQ+DINNextLTPro-Bold Type 1C WinAnsi yes yes no 354 0 LHFNBW+MinionPro-Regular Type 1C Custom yes yes yes 193 0 DVERTM+MinionPro-It Type 1C WinAnsi yes yes yes 197 0 SURIVI+DINNextLTPro-Regular Type 1C WinAnsi yes yes yes 199 0 SURIVI+DINNextLTPro-Italic Type 1C Custom yes yes yes 201 0 LHFNBW+DINNextLTPro-LightItalic Type 1C WinAnsi yes yes yes 202 0 ZHIYPU+DINNextLTPro-Light Type 1C WinAnsi yes yes yes 203 0 DVERTM+TimesNewRomanPSMT CID TrueType Identity-H yes yes yes 217 0 OWRFRQ+MinionPro-Bold Type 1C WinAnsi yes yes yes 216 0 SURIVI+DINNextLTPro-Regular Type 1C WinAnsi yes yes yes 214 0 SURIVI+DINNextLTPro-Italic Type 1C Custom yes yes yes 212 0 LHFNBW+DINNextLTPro-LightItalic Type 1C WinAnsi yes yes yes 210 0 ZHIYPU+DINNextLTPro-Light Type 1C WinAnsi yes yes yes 208 0 HJFPXE+DINNextLTPro-BoldItalic Type 1C WinAnsi yes yes yes 218 0 HJFPXE+ArialMT Type 1C WinAnsi yes yes no 226 0 HJFPXE+Arial-ItalicMT Type 1C WinAnsi yes yes no 223 0 HJFPXE+ArialMT Type 1C WinAnsi yes yes no 222 0 HJFPXE+ArialMT Type 1C Custom yes yes no 229 0 HJFPXE+ArialMT Type 1C WinAnsi yes yes no 233 0 HJFPXE+ArialMT Type 1C WinAnsi yes yes no 232 0 HJFPXE+ArialMT Type 1C Custom yes yes no 231 0 YYPNBW+Helvetica Type 1C WinAnsi yes yes no 234 0 HJFPXE+ArialMT Type 1C Custom yes yes no 240 0 HJFPXE+ArialMT Type 1C Custom yes yes no 239 0 HJFPXE+ArialMT Type 1C WinAnsi yes yes no 238 0 HJFPXE+ArialMT Type 1C WinAnsi yes yes no 237 0 HJFPXE+Arial-ItalicMT Type 1C WinAnsi yes yes no 236 0 HJFPXE+Arial-ItalicMT Type 1C WinAnsi yes yes no 235 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-10-11 03:59:55 CEST RepresentationInformation: MISO_a2024v10p001334.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-10-10 11:37:52 CEST Size: 559845 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 361 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Streptococcus suis infection on European farms is associated with an altered tonsil microbiome and resistome Children: Item: Title: Abstract Item: Title: Data Summary Item: Title: Introduction Item: Title: Methods Children: Item: Title: Animals Item: Title: Whole-genome sequencing of bacterial isolates Item: Title: Sample collection Item: Title: Amplicon sequencing Item: Title: Shotgun sequencing Item: Title: Analysis of metagenomic data Item: Title: Results Children: Item: Title: Sequencing Item: Title: The S. suis disease-associated microbiota Item: Title: Early-life microbiota diversity predicts the onset of clinical signs weeks later Item: Title: MAG analysis Item: Title: The tonsillar microbiome of piglets is similar between farms but diverged in free-range forest piglets Item: Title: Increased abundance of tetracycline ARGs in case piglets Item: Title: Comparison of the tonsillar and nasal microbiota Item: Title: S. suis diversity in the tonsillar microbiota Item: Title: Discussion Item: Title: References Info: Creator: Adobe InDesign CS6 (Windows) Producer: Adobe PDF Library 10.0.1 CreationDate: Thu Dec 19 11:54:38 CET 2024 ModDate: Thu Dec 19 11:54:40 CET 2024 ID: 0x5dcf88eaba1efe41ab940789f251a391, 0xdce8729b52208e41b6c1c0550ed0c2a7 Filters: FilterPipeline: FlateDecode Fonts: Type0: Font: BaseFont: DVERTM+TimesNewRomanPSMT Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: LHFNBW+MinionPro-Regular FontSubset: true FirstChar: 19 LastChar: 176 FontDescriptor: FontName: LHFNBW+MinionPro-Regular Flags: Serif, Nonsymbolic FontBBox: -290, -360, 1684, 989 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: HJFPXE+ArialMT FontSubset: true FirstChar: 32 LastChar: 117 FontDescriptor: FontName: HJFPXE+ArialMT Flags: Nonsymbolic FontBBox: -665, -325, 2000, 1040 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DVERTM+MinionPro-It FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: DVERTM+MinionPro-It Flags: Serif, Nonsymbolic, Italic FontBBox: -201, -360, 1684, 1002 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: HJFPXE+ArialMT FontSubset: true FirstChar: 31 LastChar: 121 FontDescriptor: FontName: HJFPXE+ArialMT Flags: Nonsymbolic FontBBox: -665, -325, 2000, 1040 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: LHFNBW+DINNextLTPro-Medium FontSubset: true FirstChar: 32 LastChar: 116 FontDescriptor: FontName: LHFNBW+DINNextLTPro-Medium Flags: Nonsymbolic FontBBox: -164, -228, 1027, 920 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: HJFPXE+ArialMT FontSubset: true FirstChar: 31 LastChar: 121 FontDescriptor: FontName: HJFPXE+ArialMT Flags: Nonsymbolic FontBBox: -665, -325, 2000, 1040 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: HJFPXE+ArialMT FontSubset: true FirstChar: 40 LastChar: 116 FontDescriptor: FontName: HJFPXE+ArialMT Flags: Nonsymbolic FontBBox: -665, -325, 2000, 1040 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: HJFPXE+ArialMT FontSubset: true FirstChar: 32 LastChar: 117 FontDescriptor: FontName: HJFPXE+ArialMT Flags: Nonsymbolic FontBBox: -665, -325, 2000, 1040 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: YYPNBW+Helvetica FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: YYPNBW+Helvetica Flags: Nonsymbolic FontBBox: -951, -481, 1446, 1122 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: HJFPXE+Arial-ItalicMT FontSubset: true FirstChar: 108 LastChar: 121 FontDescriptor: FontName: HJFPXE+Arial-ItalicMT Flags: Nonsymbolic FontBBox: -517, -325, 1359, 998 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: HJFPXE+Arial-ItalicMT FontSubset: true FirstChar: 32 LastChar: 117 FontDescriptor: FontName: HJFPXE+Arial-ItalicMT Flags: Nonsymbolic FontBBox: -517, -325, 1359, 998 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ZHIYPU+DINNextLTPro-Light FontSubset: true FirstChar: 28 LastChar: 243 FontDescriptor: FontName: ZHIYPU+DINNextLTPro-Light Flags: Nonsymbolic FontBBox: -148, -213, 985, 914 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: HJFPXE+ArialMT FontSubset: true FirstChar: 32 LastChar: 119 FontDescriptor: FontName: HJFPXE+ArialMT Flags: Nonsymbolic FontBBox: -665, -325, 2000, 1040 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: SURIVI+DINNextLTPro-Italic FontSubset: true FirstChar: 31 LastChar: 117 FontDescriptor: FontName: SURIVI+DINNextLTPro-Italic Flags: Nonsymbolic FontBBox: -155, -212, 972, 916 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: HJFPXE+ArialMT FontSubset: true FirstChar: 49 LastChar: 119 FontDescriptor: FontName: HJFPXE+ArialMT Flags: Nonsymbolic FontBBox: -665, -325, 2000, 1040 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: SURIVI+DINNextLTPro-Regular FontSubset: true FirstChar: 27 LastChar: 248 FontDescriptor: FontName: SURIVI+DINNextLTPro-Regular Flags: Nonsymbolic FontBBox: -156, -213, 1008, 917 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: HJFPXE+ArialMT FontSubset: true FirstChar: 31 LastChar: 117 FontDescriptor: FontName: HJFPXE+ArialMT Flags: Nonsymbolic FontBBox: -665, -325, 2000, 1040 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: HJFPXE+ArialMT FontSubset: true FirstChar: 31 LastChar: 117 FontDescriptor: FontName: HJFPXE+ArialMT Flags: Nonsymbolic FontBBox: -665, -325, 2000, 1040 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: OWRFRQ+MinionPro-Bold FontSubset: true FirstChar: 65 LastChar: 121 FontDescriptor: FontName: OWRFRQ+MinionPro-Bold Flags: Serif, Nonsymbolic FontBBox: -319, -360, 1684, 1024 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: HJFPXE+DINNextLTPro-BoldItalic FontSubset: true FirstChar: 32 LastChar: 117 FontDescriptor: FontName: HJFPXE+DINNextLTPro-BoldItalic Flags: Nonsymbolic FontBBox: -163, -234, 1048, 924 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: OQKFWQ+DINNextLTPro-Bold FontSubset: true FirstChar: 31 LastChar: 150 FontDescriptor: FontName: OQKFWQ+DINNextLTPro-Bold Flags: Nonsymbolic FontBBox: -170, -238, 1076, 925 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: HJFPXE+ArialMT FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: HJFPXE+ArialMT Flags: Nonsymbolic FontBBox: -665, -325, 2000, 1040 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LHFNBW+DINNextLTPro-LightItalic FontSubset: true FirstChar: 32 LastChar: 252 FontDescriptor: FontName: LHFNBW+DINNextLTPro-LightItalic Flags: Nonsymbolic FontBBox: -155, -213, 947, 913 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: HJFPXE+Arial-ItalicMT FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: HJFPXE+Arial-ItalicMT Flags: Nonsymbolic FontBBox: -517, -325, 1359, 998 FontFile3: true Encoding: WinAnsiEncoding CIDFontType2: Font: BaseFont: DVERTM+TimesNewRomanPSMT CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: DVERTM+TimesNewRomanPSMT Flags: Serif, Symbolic FontBBox: -568, -307, 2046, 1040 FontFile2: true XMP: 2024-12-19T15:54:38+05:30 2024-12-19T15:54:40+05:30 2024-12-19T15:54:40+05:30 Adobe InDesign CS6 (Windows) uuid:4d7969f0-ef32-48f3-969a-ab7c57966fe0 xmp.did:F5ECED53252168118083E0C8553B9672 xmp.id:9BE02271F3BDEF119870975C420C28D2 proof:pdf xmp.iid:9AE02271F3BDEF119870975C420C28D2 xmp.did:C2867969D1C5E611B91BCD08C2A06E14 xmp.did:F5ECED53252168118083E0C8553B9672 default converted from application/x-indesign to application/pdf Adobe InDesign CS6 (Windows) / 2024-12-19T15:54:38+05:30 f807eba0-911f-461f-8cf5-b307d18be3f2 application/pdf Adobe PDF Library 10.0.1 False Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 42, 750, 166, 721 Annotation: Subtype: Link Rect: 43, 41, 78, 26 Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 398, 626, 412, 612 ActionDest: 168 Annotation: Subtype: Link Rect: 468, 614, 482, 600 ActionDest: 168 Annotation: Subtype: Link Rect: 358, 602, 363, 588 ActionDest: 168 Annotation: Subtype: Link Rect: 451, 590, 456, 577 ActionDest: 168 Annotation: Subtype: Link Rect: 48, 561, 68, 548 ActionDest: 168 Annotation: Subtype: Link Rect: 103, 549, 112, 536 ActionDest: 185 Annotation: Subtype: Link Rect: 415, 537, 425, 524 ActionDest: 185 Annotation: Subtype: Link Rect: 79, 514, 103, 500 ActionDest: 185 Annotation: Subtype: Link Rect: 448, 497, 473, 483 ActionDest: 168 Annotation: Subtype: Link Rect: 193, 473, 217, 459 ActionDest: 185 Annotation: Subtype: Link Rect: 332, 184, 360, 171 ActionDest: 26 Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 229, 273, 239, 260 ActionDest: 185 Annotation: Subtype: Link Rect: 374, 273, 383, 260 ActionDest: 185 Annotation: Subtype: Link Rect: 534, 273, 544, 260 ActionDest: 185 Annotation: Subtype: Link Rect: 245, 129, 255, 116 ActionDest: 185 Annotation: Subtype: Link Rect: 482, 129, 492, 116 ActionDest: 185 Annotation: Subtype: Link Rect: 362, 106, 371, 93 ActionDest: 185 Annotation: Subtype: Link Rect: 468, 83, 477, 70 ActionDest: 185 Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 518, 716, 528, 703 ActionDest: 185 Annotation: Subtype: Link Rect: 74, 705, 83, 691 ActionDest: 185 Annotation: Subtype: Link Rect: 280, 583, 442, 570 Annotation: Subtype: Link Rect: 82, 549, 92, 535 ActionDest: 185 Annotation: Subtype: Link Rect: 516, 537, 526, 524 ActionDest: 185 Annotation: Subtype: Link Rect: 110, 526, 120, 512 ActionDest: 185 Annotation: Subtype: Link Rect: 340, 526, 349, 512 ActionDest: 185 Annotation: Subtype: Link Rect: 519, 526, 529, 512 ActionDest: 185 Annotation: Subtype: Link Rect: 278, 503, 287, 489 ActionDest: 185 Annotation: Subtype: Link Rect: 93, 440, 102, 426 ActionDest: 185 Annotation: Subtype: Link Rect: 48, 254, 58, 240 ActionDest: 185 Annotation: Subtype: Link Rect: 472, 106, 499, 93 ActionDest: 83 Annotation: Subtype: Link Rect: 48, 95, 58, 81 ActionDest: 185 Page: Sequence: 5 Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 231, 693, 258, 679 ActionDest: 83 Annotation: Subtype: Link Rect: 461, 669, 488, 656 ActionDest: 83 Annotation: Subtype: Link Rect: 460, 522, 482, 508 ActionDest: 87 Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 451, 667, 488, 654 ActionDest: 98 Annotation: Subtype: Link Rect: 156, 644, 194, 631 ActionDest: 98 Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 85, 690, 95, 677 ActionDest: 185 Annotation: Subtype: Link Rect: 271, 644, 298, 631 ActionDest: 98 Annotation: Subtype: Link Rect: 429, 610, 434, 596 ActionDest: 168 Annotation: Subtype: Link Rect: 311, 587, 337, 573 ActionDest: 98 Annotation: Subtype: Link Rect: 293, 489, 320, 475 ActionDest: 98 Annotation: Subtype: Link Rect: 252, 380, 274, 366 ActionDest: 107 Page: Sequence: 9 Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 330, 507, 356, 493 ActionDest: 126 Annotation: Subtype: Link Rect: 164, 357, 173, 344 ActionDest: 185 Annotation: Subtype: Link Rect: 468, 323, 495, 309 ActionDest: 126 Annotation: Subtype: Link Rect: 94, 300, 120, 286 ActionDest: 126 Annotation: Subtype: Link Rect: 376, 271, 385, 258 ActionDest: 185 Annotation: Subtype: Link Rect: 516, 225, 544, 212 ActionDest: 126 Annotation: Subtype: Link Rect: 364, 135, 389, 121 ActionDest: 185 Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 209, 717, 218, 703 ActionDest: 185 Annotation: Subtype: Link Rect: 507, 671, 517, 657 ActionDest: 185 Annotation: Subtype: Link Rect: 218, 556, 227, 542 ActionDest: 185 Annotation: Subtype: Link Rect: 116, 400, 125, 387 ActionDest: 185 Annotation: Subtype: Link Rect: 156, 354, 166, 341 ActionDest: 185 Annotation: Subtype: Link Rect: 460, 302, 469, 289 ActionDest: 185 Annotation: Subtype: Link Rect: 104, 268, 114, 254 ActionDest: 185 Annotation: Subtype: Link Rect: 48, 256, 71, 243 ActionDest: 185 Annotation: Subtype: Link Rect: 333, 205, 357, 191 ActionDest: 185 Page: Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 258, 705, 283, 691 ActionDest: 187 Annotation: Subtype: Link Rect: 331, 705, 341, 691 ActionDest: 187 Annotation: Subtype: Link Rect: 337, 584, 347, 571 ActionDest: 187 Annotation: Subtype: Link Rect: 427, 561, 452, 548 ActionDest: 187 Annotation: Subtype: Link Rect: 530, 384, 549, 375 Annotation: Subtype: Link Rect: 45, 375, 89, 366 Annotation: Subtype: Link Rect: 323, 375, 403, 366 Page: Sequence: 13 Page: Sequence: 14 Checksum: c792d93e Type: CRC32 Checksum: 7d99ace290591f2f337b170fe5ba88a0 Type: MD5 Checksum: 95785a7f64663637083069685d8f510f4ee1e689 Type: SHA-1 Checksum: 0503f1bfdf421a648215b4707765750887938454cdf6c70640692d31d2ff50db Type: SHA-256