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Title:           Romidepsin and Afatinib Abrogate Jak-Signal Transducer and Activator of Transcription Signaling and Elicit Synergistic Antitumor Effects in Cutaneous T-Cell Lymphoma
Subject:         Journal of Investigative Dermatology, 144 (2024) 1579-1597. doi:10.1016/j.jid.2023.12.010
Author:          Bobby B. Shih
Creator:         Elsevier
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     Item: 
      Title: Romidepsin and Afatinib Abrogate Jak–Signal Transducer and Activator of Transcription Signaling and Elicit Synergistic Anti ...
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       Item: 
        Title: Introduction
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       Item: 
        Title: Results
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        Children: 
         Item: 
          Title: High-throughput drug screening identifies romidepsin and afatinib synergism
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         Item: 
          Title: Combination with afatinib dimaleate overcomes acquired romidepsin resistance in CTCL
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         Item: 
          Title: Romidepsin and afatinib dimaleate induce downregulation of Jak–STAT signaling in CTCL
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       Item: 
        Title: Discussion
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       Item: 
        Title: Materials and Methods
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        Children: 
         Item: 
          Title: Cell lines
          Destination: slink4
         Item: 
          Title: Cell culture
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         Item: 
          Title: Primary CTCL samples
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         Item: 
          Title: High-throughput drug screening
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         Item: 
          Title: Cell cycle analyses
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         Item: 
          Title: Drugs
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         Item: 
          Title: Cell proliferation and drug response analyses
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         Item: 
          Title: Evaluating synergy using nonconstant ratio dose–response design
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         Item: 
          Title: Apoptosis analyses
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         Item: 
          Title: RNA isolation
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         Item: 
          Title: RNA-sequencing and gene expression profiling
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         Item: 
          Title: Generation of luciferase expression CTCL cell lines
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         Item: 
          Title: Mouse husbandry and procedures
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         Item: 
          Title: Western blot analysis
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         Item: 
          Title: Statistical analyses
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       Item: 
        Title: Data Availability Statement
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       Item: 
        Title: ORCIDs
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       Item: 
        Title: Conflict of Interest
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       Item: 
        Title: Acknowledgments
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        Title: Author Contributions
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        Title: Supplementary Material
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        Title: References
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       Item: 
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    Title: Romidepsin and Afatinib Abrogate Jak-Signal Transducer and Activator of Transcription Signaling and Elicit Synergistic Antitumor Effects in Cutaneous T-Cell Lymphoma
    Author: Bobby B. Shih
    Subject: Journal of Investigative Dermatology, 144 (2024) 1579-1597. doi:10.1016/j.jid.2023.12.010
    Creator: Elsevier
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   Type: CRC32
  Checksum: a3a11ecac7ef77711281a37c77d9ca05
   Type: MD5
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