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Destination: B2 Item: Title: Effect of p95HER2.CAR T cells on different cancer models Destination: B3 Item: Title: Development of a next generation p95HER2.CAR T Destination: B4 Item: Title: Anti-tumor efficacy of p95HER2.CAR-TECH2Me T cells Destination: B5 Item: Title: Discussion Destination: A2 Item: Title: Methods Destination: A3 Children: Item: Title: Study design Destination: B6 Item: Title: Cell lines Destination: B7 Item: Title: Tumor samples and patient-derived tumor xenografts Destination: B8 Item: Title: p95HER2 antibodies Destination: B9 Item: Title: Membrane proteome array Destination: B10 Item: Title: Generation of retroviral vectors containing CAR constructs Destination: B11 Item: Title: PBMC isolation Destination: B12 Item: Title: CAR T cell production Destination: B13 Item: Title: In vitro cytotoxicity, activation and proliferation assays Destination: B14 Item: Title: In vivo tumor growth assays Destination: B15 Item: Title: Immunohistochemical analysis of HER2 and p95HER2 expression Destination: B16 Item: Title: TECH2 binding assays Destination: B17 Item: Title: Quantification of TECH2Me Destination: B18 Item: Title: Metastasis assays Destination: B19 Item: Title: Statistics Destination: B20 Item: Title: Reporting summary Destination: B21 Item: Title: Data availability Destination: M1 Item: Title: References Destination: A4 Item: Title: Acknowledgements Destination: A5 Item: Title: Author contributions Destination: A6 Item: Title: Competing interests Destination: A7 Item: Title: Additional information Destination: M3 Info: Title: Generation of chimeric antigen receptor T cells targeting p95HER2 in solid tumors Author: Macarena Román Alonso Subject: Nature Communications, doi:10.1038/s41467-024-53265-7 Keywords: Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Wed Oct 30 11:59:15 CET 2024 ModDate: Wed Nov 06 13:42:41 CET 2024 ID: 0x993dd53cea61720a9fd01b724fd2c07f, 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FontFile3: true Encoding: WinAnsiEncoding XMP: application/pdf doi:10.1038/s41467-024-53265-7 Generation of chimeric antigen receptor T cells targeting p95HER2 in solid tumors Macarena Román Alonso Ariadna Grinyó-Escuer Santiago Duro-Sánchez Irene Rius-Ruiz Marta Bort-Brusca Marta Escorihuela Susana Maqueda-Marcos Sandra Pérez-Ramos Judit Gago Vanesa Nogales Martín Espinosa-Bravo Vicente Peg Santiago Escrivá-de-Romaní Laia Foradada Laura Soucek Irene Braña Vladimir Galvao Silvia Martín-Lluesma Ekkehard Moessner Christian Klein Elena Garralda Cristina Saura Joaquín Arribas Springer US Nature Communications, doi:10.1038/s41467-024-53265-7 10.1038/s41467-024-53265-7 http://dx.doi.org/10.1038/s41467-024-53265-7 journal Nature Communications © 2024, The Author(s) 2041-1723 10.1038/s41467-024-53265-7 springer.com springerlink.com 2010-04-23 True 10.1038/s41467-024-53265-7 springer.com springerlink.com Springer 2024-11-06T13:42:41+01:00 2024-10-30T15:59:15+05:30 2024-11-06T13:42:41+01:00 True 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