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edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'alz14312-supitem-0002' cannot be found ID: PDF-HUL-122 Offset: 627106 MIMEtype: application/pdf PDFMetadata: Objects: 0 FreeObjects: 2 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Gaps in biomedical research in frontotemporal dementia: A call for diversity and disparities focused research Destination: chapter..1 Children: Item: Title: Abstract Destination: section*.2 Item: Title: 1 | INTRODUCTION Destination: section..1.1 Item: Title: 2 | UPDATE ON SOCIOCULTURAL FACTORS INFLUENCING FTD RECOGNITION AND DEVELOPMENT AND VALIDATION OF DIAGNOSTIC TOOLS ACROSS THE GLOBE Destination: section..1.2 Item: Title: 3 | EPIDEMIOLOGY Destination: section..1.3 Children: Item: Title: 3.1 | Frequency and life expectancy Destination: subsection..1.3.1 Item: Title: 3.2 | Effects of structural and social determinants of health and risk factors Destination: subsection..1.3.2 Item: Title: 3.3 | Effects of vascular disorders Destination: subsection..1.3.3 Item: Title: 3.4 | Effects of head trauma Destination: subsection..1.3.4 Item: Title: 4 | GENETICS Destination: section..1.4 Children: Item: Title: 4.1 | South America Destination: subsection..1.4.1 Item: Title: 4.2 | Africa and the Middle East Destination: subsection..1.4.2 Item: Title: 4.3 | Asia Destination: subsection..1.4.3 Item: Title: 4.4 | Oceania Destination: subsection..1.4.4 Item: Title: 4.5 | Impact of AD and risk genes in non-European populations Destination: subsection..1.4.5 Item: Title: 5 | BIOMARKERS Destination: section..1.5 Children: Item: Title: 5.1 | Current status of biofluid biomarker research Destination: subsection..1.5.1 Item: Title: 5.2 | Current status of imaging biomarker research Destination: subsection..1.5.2 Item: Title: 5.3 | Current status of pathology studies Destination: subsection..1.5.3 Item: Title: 5.4 | Considerations of cost of biomarkers for low- and middle-income countries Destination: subsection..1.5.4 Item: Title: 6 | TREATMENT Destination: section..1.6 Children: Item: Title: 6.1 | Non-invasive brain stimulation trials in FTD Destination: subsection..1.6.1 Item: Title: 6.2 | Potential for gene therapies Destination: subsection..1.6.2 Item: Title: 7 | INFRASTRUCTURE AND OUTREACH NEEDS Destination: section..1.7 Children: Item: Title: 7.1 | Limited clinical expertise and access to diagnosis Destination: subsection..1.7.1 Children: Item: Title: 7.1.1 | Europe Destination: subsubsection..1.7.1.1 Item: Title: 7.1.2 | North America Destination: subsubsection..1.7.1.2 Item: Title: 7.1.3 | South America Destination: subsubsection..1.7.1.3 Item: Title: 7.1.4 | Oceania Destination: subsubsection..1.7.1.4 Item: Title: 7.1.5 | Africa Destination: subsubsection..1.7.1.5 Item: Title: 7.1.6 | Middle East Destination: subsubsection..1.7.1.6 Item: Title: 7.1.7 | Asia Destination: subsubsection..1.7.1.7 Item: Title: 7.2 | Access to research expertise, funding, and resources Destination: subsection..1.7.2 Children: Item: Title: 7.2.1 | North America/ Europe Destination: subsubsection..1.7.2.1 Item: Title: 7.2.2 | South America Destination: subsubsection..1.7.2.2 Item: Title: 7.2.3 | Oceania Destination: subsubsection..1.7.2.3 Item: Title: 7.2.4 | Africa Destination: subsubsection..1.7.2.4 Item: Title: 7.2.5 | Middle East Destination: subsubsection..1.7.2.5 Item: Title: 7.2.6 | Asia Destination: subsubsection..1.7.2.6 Item: Title: 7.3 | Access to FTD patient advocacy groups Destination: subsection..1.7.3 Item: Title: 8 | SUMMARY OF GAPS AND NEXT STEPS Destination: section..1.8 Item: Title: AFFILIATIONS Destination: section*.4 Item: Title: ACKNOWLEDGMENTS Destination: section*.6 Item: Title: CONFLICT OF INTEREST STATEMENT Destination: section*.8 Item: Title: CONSENT STATEMENT Destination: section*.10 Item: Title: ORCID Destination: section*.12 Item: Title: REFERENCES Destination: section*.14 Item: Title: 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