4db8b62706d9fbd0213b587bdcf1cb42 3.Clinical_and_Epidemiological_Characteristics_of_the.pdf b90cc9b60a62bf7da4fb0fd98193d80bf9494db1 3.Clinical_and_Epidemiological_Characteristics_of_the.pdf 0baa3ad6928866d25831899dd5ab33112a916ff9e50a091d6ea4d78175d34fc3 3.Clinical_and_Epidemiological_Characteristics_of_the.pdf Title: Clinical and Epidemiological Characteristics of the 2022 Mpox Outbreak in Spain (CEME-22 Study) Subject: DOI: 10.1093/ofid/ofae105; Open Forum Infectious Diseases, 11, 3, 2024-02-26.; Abstract: Background: We conducted a multicentric national study (SEIMC-CEME-22), to describe the clinical and epidemiological profile of the mpox outbreak in Spain, including the management of the disease. Methods: This was a retrospective national observational study conducted by Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC) and Foundation SEIMC-GESIDA. We included patients with a confirmed mpox diagnosis before 13 July 2022, and attended at the Spanish health network (the early phase of the outbreak). Epidemiological, clinical, and therapeutic data were collected. Results: Of a total of 1472 patients from 52 centers included, 99% of them were cisgender men, mostly middle-aged, and 98.6% were residents in Spain. The main suspected route of transmission was sexual exposure, primarily among MSM. Occupational exposure was reported in 6 patients. Immunosuppression was present in 40% of Keywords: emerging infections; HIV; mpox; STI; tecovirimat Author: G. Ramírez-Olivencia Creator: Servigistics Arbortext Advanced Print Publisher 11.1.4546/W-x64 Producer: PDFlib+PDI 9.0.7p3 (C++/Win64) CreationDate: Fri Mar 29 14:22:52 2024 CET ModDate: Mon Jun 8 18:55:19 2026 CEST Custom Metadata: yes Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 8 Encrypted: no Page size: 593.972 x 782.986 pts Page rot: 0 File size: 461015 bytes Optimized: yes PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- VZELZO+MinionPro-Regular Type 1C Custom yes yes yes 700 0 MZMEQB+UniversLTStd-BoldCn Type 1C Custom yes yes yes 703 0 OHNMXZ+UniversLTStd-LightCn Type 1C Custom yes yes yes 706 0 VDWSDN+MinionPro-BoldIt Type 1C Custom yes yes yes 709 0 EAOLFE+STIXGeneral-Regular Type 1C Custom yes yes yes 712 0 UTRGOK+MinionPro-Bold Type 1C Custom yes yes yes 715 0 JDQJAF+UniversLTStd-LightCnObl Type 1C Custom yes yes yes 718 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Ramírez-Olivencia M. Velasco Arribas M. M. Vera García J. Casabona M. J. Martínez F. J. Membrillo De Novales DOI: 10.1093/ofid/ofae105; Open Forum Infectious Diseases, 11, 3, 2024-02-26.; Abstract: Background: We conducted a multicentric national study (SEIMC-CEME-22), to describe the clinical and epidemiological profile of the mpox outbreak in Spain, including the management of the disease. Methods: This was a retrospective national observational study conducted by Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC) and Foundation SEIMC-GESIDA. We included patients with a confirmed mpox diagnosis before 13 July 2022, and attended at the Spanish health network (the early phase of the outbreak). Epidemiological, clinical, and therapeutic data were collected. Results: Of a total of 1472 patients from 52 centers included, 99% of them were cisgender men, mostly middle-aged, and 98.6% were residents in Spain. The main suspected route of transmission was sexual exposure, primarily among MSM. Occupational exposure was reported in 6 patients. Immunosuppression was present in 40% of © The Author(s) 2024. Published by Oxford University Press on behalf of Infectious Diseases Society of America. emerging infections HIV mpox STI tecovirimat Journal Open Forum Infectious Diseases © The Author(s) 2024. 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