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Transpl Int 37:13919. doi: 10.3389/ti.2024.13919 Keywords: AlloSeq, dd-cfDNA, liquid biopsy, allograft rejection, non-invasive diagnosis Author: Alexandre Loupy Creator: Arbortext Advanced Print Publisher 9.1.510/W Unicode Producer: Acrobat Distiller 7.0 (Windows) CreationDate: Thu Dec 12 18:45:16 2024 CET ModDate: Mon Oct 5 17:04:34 2026 CEST Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 12 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 2099372 bytes Optimized: yes PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- JMHLGP+AdvOTb316e848.B Type 1C WinAnsi yes yes no 458 0 JMHLIA+AdvOT810131c9.I Type 1C WinAnsi yes yes no 460 0 JMHLIB+AdvOT3e5a32a2.I Type 1C WinAnsi yes yes no 462 0 JMHLIC+AdvOT3e5a32a2.I+20 Type 1C WinAnsi yes yes no 465 0 JMHLJD+AdvOTd86a71d2 Type 1C WinAnsi yes yes no 467 0 JMHLJE+AdvOTd86a71d2+20 Type 1C WinAnsi yes yes no 477 0 JMHLJF+AdvOT310e2d14 Type 1C WinAnsi yes yes no 469 0 JMHLJG+AdvOTd86a71d2+fb Type 1C Custom yes yes yes 474 0 JMHMAE+AdvOTaef7d8ec.BI Type 1C WinAnsi yes yes no 476 0 JMIGKE+AdvOT1ef757c0 Type 1C WinAnsi yes yes no 242 0 JMIGKF+AdvOT1ef757c0+fb Type 1C Custom yes yes yes 243 0 JMIGKG+AdvOT1ef757c0+20 Type 1C WinAnsi yes yes no 253 0 JMIGOF+AdvOT1ef757c0+03 Type 1C Custom yes yes yes 255 0 JMIGOG+AdvOT1ef757c0+22 Type 1C Custom yes yes no 264 0 JMIHBG+AdvOTb65e897d.B Type 1C WinAnsi yes yes no 268 0 JMIHEG+AdvOT3e5a32a2.I+fb Type 1C Custom yes yes yes 274 0 JMJAIO+AdvOT7d6df7ab.I Type 1C WinAnsi yes yes no 277 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2026-10-09 03:59:12 CEST RepresentationInformation: ti-37-13919.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2026-10-08 10:07:03 CEST Size: 2099372 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 523 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Evaluation of a Decentralized Donor-Derived Cell-Free DNA Assay for Kidney Allograft Rejection Monitoring Destination: titlink1 Children: Item: Title: Introduction Destination: flink1 Item: Title: Materials and Methods Destination: flink2 Children: Item: Title: Study Design and Population Destination: slink1 Item: Title: Data Collection Destination: slink2 Item: Title: Circulating Nucleic Acid Extraction Destination: slink3 Item: Title: Decentralized dd-cfDNA Measurement Destination: slink4 Item: Title: Centralized dd-cfDNA Measurement Destination: slink5 Item: Title: Statistical Analysis Destination: slink6 Item: Title: Results Destination: flink3 Children: Item: Title: Characteristics of Patients at Baseline and at the Time of dd-cfDNA Measurement Destination: slink7 Item: Title: Comparison of Decentralized and Centralized dd-cfDNA Results Destination: slink8 Item: Title: Association and Discrimination of Decentralized and Centralized dd-cfDNA Results With Rejection Destination: slink9 Item: Title: Sensitivity Analyses Destination: slink10 Item: Title: Discussion Destination: flink4 Item: Title: Conclusion Destination: flink5 Item: Title: Data Availability Statement Destination: flink6 Item: Title: Ethics Statement Destination: flink7 Item: Title: Author Contributions Destination: flink8 Item: Title: Funding Destination: flink9 Item: Title: Conflict of Interest Destination: flink10 Item: Title: Generative AI Statement Destination: flink11 Item: Title: Acknowledgments Destination: slink11 Item: Title: Supplementary Material Destination: flink12 Item: Title: References Destination: rlink1 Info: Title: Author: Alexandre Loupy Subject: Loupy A, Certain A, Tangprasertchai NS, Racapé M, Ursule-Dufait C, Benbadi K, Raynaud M, Vaskova E, Marchis C, Casas S, Hague T, Bestard O, Kervella D, Lefaucheur C, Viard T and Aubert O (2024), Evaluation of a Decentralized Donor-Derived Cell-Free DNA Assay for Kidney Allograft Rejection Monitoring. 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Tangprasertchai Maud Racapé Cindy Ursule-Dufait Kawthar Benbadi Marc Raynaud Evgeniya Vaskova Corina Marchis Sílvia Casas Tim Hague Oriol Bestard Delphine Kervella Carmen Lefaucheur Thierry Viard Olivier Aubert Loupy A, Certain A, Tangprasertchai NS, Racapé M, Ursule-Dufait C, Benbadi K, Raynaud M, Vaskova E, Marchis C, Casas S, Hague T, Bestard O, Kervella D, Lefaucheur C, Viard T and Aubert O (2024), Evaluation of a Decentralized Donor-Derived Cell-Free DNA Assay for Kidney Allograft Rejection Monitoring. Transpl Int 37:13919. doi: 10.3389/ti.2024.13919 AlloSeq dd-cfDNA liquid biopsy allograft rejection non-invasive diagnosis Copyright © 2024 Loupy, Certain, Tangprasertchai, Racapé, Ursule-Dufait, Benbadi, Raynaud, Vaskova, Marchis, Casas, Hague, Bestard, Kervella, Lefaucheur, Viard and Aubert. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. 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