3895fd549928a5a52ce356261eafaf9c 336804.pdf 6060d975ab0ce5841df23ed72fc7929dcfcddf90 336804.pdf d52a317431d1e6e766a039592fc288f0b59b1d9c7295799fa86821541131bcb0 336804.pdf Title: Is estimated exposure an accurate surrogate for measured fludarabine levels in patients with CAR T-cell therapy? Subject: BLOOD ADVANCES, 8 (2024) 2130-2132. doi:10.1182/bloodadvances.2023011433 Author: Mario Andrés Sánchez-Salinas Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows); modified using iTextSharp.LGPLv2.Core 3.7.4.0 CreationDate: Tue May 7 00:02:01 2024 CEST ModDate: Tue Oct 6 10:54:44 2026 CEST Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 3 Encrypted: no Page size: 593.972 x 782.986 pts Page rot: 0 File size: 442069 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- EJBBFG+AdvOT5921cb55.B Type 1C WinAnsi yes yes no 35 0 EJBBGG+AdvTT51434264 Type 1C WinAnsi yes yes no 255 0 EJBBGH+AdvTT51434264+fb Type 1C Custom yes yes yes 256 0 EJBBGI+AdvOT333dc5e5 Type 1C WinAnsi yes yes no 36 0 EJBBGJ+Advstixtexrm Type 1C Custom yes yes yes 103 0 EJBBHK+AdvOT333dc5e5+20 Type 1C WinAnsi yes yes no 37 0 EJBBHL+AdvOT333dc5e5+fb Type 1C Custom yes yes yes 38 0 EJBBHM+AdvOT702dc698.I Type 1C WinAnsi yes yes no 39 0 EJBBHN+AdvstixtSym Type 1C Custom yes yes yes 40 0 EJBBJN+AdvOTee8bf91a Type 1C WinAnsi yes yes no 41 0 CXZADT+ArialMT CID TrueType Identity-H yes yes yes 1 0 EJBBLP+AkzidenzGroteskBE-Cn Type 1C WinAnsi yes yes no 30 0 AkzidenzGroteskBE-It Type 1C WinAnsi yes no no 31 0 EJBBMB+AkzidenzGroteskBE-Bold Type 1C WinAnsi yes yes no 32 0 EJBBOC+AdvOT5921cb55.B+fb Type 1C Custom yes yes yes 33 0 EJBBMC+SymbolMT CID TrueType Identity-H yes yes no 34 0 EJBBLO+AkzidenzGroteskBE-Regular Type 1C WinAnsi yes yes no 42 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2026-10-07 04:00:48 CEST RepresentationInformation: 336804.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2026-10-06 10:55:16 CEST Size: 442069 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 308 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Is estimated exposure an accurate surrogate for measured fludarabine levels in patients with CAR T-cell therapy? Destination: titlink1 Children: Item: Title: References Destination: blink1 Info: Title: Is estimated exposure an accurate surrogate for measured fludarabine levels in patients with CAR T-cell therapy? Author: Mario Andrés Sánchez-Salinas Subject: BLOOD ADVANCES, 8 (2024) 2130-2132. doi:10.1182/bloodadvances.2023011433 Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows); modified using iTextSharp.LGPLv2.Core 3.7.4.0 CreationDate: Tue May 07 00:32:01 CEST 2024 ModDate: Tue Oct 06 10:54:44 CEST 2026 ID: 0x3d00ad1ef70c6af67e612e84d4870f91, 0x6ecc0f1845711a7868385587d30b1a2c Filters: FilterPipeline: FlateDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 296 ImageHeight: 64 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 296 ImageHeight: 64 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Fonts: Type0: Font: BaseFont: CXZADT+ArialMT Encoding: Identity-H ToUnicode: true Font: BaseFont: EJBBMC+SymbolMT Encoding: Identity-H Type1: Font: BaseFont: EJBBGH+AdvTT51434264+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: EJBBGH+AdvTT51434264+fb Flags: Symbolic FontBBox: 19, 0, 979, 770 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EJBBMB+AkzidenzGroteskBE-Bold FontSubset: true FirstChar: 65 LastChar: 66 FontDescriptor: FontName: EJBBMB+AkzidenzGroteskBE-Bold Flags: Nonsymbolic, ForceBold FontBBox: -166, -250, 1222, 927 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EJBBOC+AdvOT5921cb55.B+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: EJBBOC+AdvOT5921cb55.B+fb Flags: Symbolic FontBBox: 0, 0, 572, 708 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EJBBFG+AdvOT5921cb55.B FontSubset: true FirstChar: 45 LastChar: 119 FontDescriptor: FontName: EJBBFG+AdvOT5921cb55.B Flags: Nonsymbolic FontBBox: -62, -250, 1104, 916 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EJBBGI+AdvOT333dc5e5 FontSubset: true FirstChar: 37 LastChar: 237 FontDescriptor: FontName: EJBBGI+AdvOT333dc5e5 Flags: Nonsymbolic FontBBox: -31, -250, 1010, 937 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EJBBHK+AdvOT333dc5e5+20 FontSubset: true FirstChar: 146 LastChar: 150 FontDescriptor: FontName: EJBBHK+AdvOT333dc5e5+20 Flags: Nonsymbolic FontBBox: -145, -145, 1218, 708 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EJBBHL+AdvOT333dc5e5+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: EJBBHL+AdvOT333dc5e5+fb Flags: Symbolic FontBBox: 0, 0, 416, 697 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EJBBHM+AdvOT702dc698.I FontSubset: true FirstChar: 50 LastChar: 121 FontDescriptor: FontName: EJBBHM+AdvOT702dc698.I Flags: Nonsymbolic FontBBox: -93, -250, 1104, 947 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EJBBGJ+Advstixtexrm FontSubset: true FirstChar: 1 LastChar: 4 FontDescriptor: FontName: EJBBGJ+Advstixtexrm Flags: Symbolic FontBBox: -385, -229, 1041, 729 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EJBBHN+AdvstixtSym FontSubset: true FirstChar: 1 LastChar: 4 FontDescriptor: FontName: EJBBHN+AdvstixtSym Flags: Symbolic FontBBox: -20, -1114, 1135, 822 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EJBBJN+AdvOTee8bf91a FontSubset: true FirstChar: 44 LastChar: 89 FontDescriptor: FontName: EJBBJN+AdvOTee8bf91a Flags: Nonsymbolic FontBBox: -41, -250, 1010, 958 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EJBBLO+AkzidenzGroteskBE-Regular FontSubset: true FirstChar: 32 LastChar: 120 FontDescriptor: FontName: EJBBLO+AkzidenzGroteskBE-Regular Flags: Nonsymbolic FontBBox: -155, -250, 1227, 944 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EJBBLP+AkzidenzGroteskBE-Cn FontSubset: true FirstChar: 32 LastChar: 120 FontDescriptor: FontName: EJBBLP+AkzidenzGroteskBE-Cn Flags: Nonsymbolic FontBBox: -134, -250, 875, 901 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EJBBGG+AdvTT51434264 FontSubset: true FirstChar: 45 LastChar: 121 FontDescriptor: FontName: EJBBGG+AdvTT51434264 Flags: Serif, Nonsymbolic FontBBox: -10, -239, 1031, 927 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AkzidenzGroteskBE-It FirstChar: 0 LastChar: 255 FontDescriptor: FontName: AkzidenzGroteskBE-It Flags: Nonsymbolic, Italic FontBBox: -123, -250, 1303, 952 FontFile3: true Encoding: WinAnsiEncoding CIDFontType2: Font: BaseFont: EJBBMC+SymbolMT CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: EJBBMC+SymbolMT Flags: Symbolic FontBBox: 0, -220, 1113, 1005 FontFile2: true Font: BaseFont: CXZADT+ArialMT CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: CXZADT+ArialMT Flags: Nonsymbolic FontBBox: -664, -324, 2000, 1039 FontFile2: true XMP: application/pdf doi:10.1182/bloodadvances.2023011433 Is estimated exposure an accurate surrogate for measured fludarabine levels in patients with CAR T-cell therapy? Mario Andrés Sánchez-Salinas Marta Miarons Iñaki F. Troconiz Víctor Navarro Javier Varela Gloria Iacoboni Pere Barba BLOOD ADVANCES, 8 (2024) 2130-2132. doi:10.1182/bloodadvances.2023011433 The American Society of Hematology journal BLOOD ADVANCES © 2024 by The American Society of Hematology. Licensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0), permitting only noncommercial, nonderivative use with attribution. All other rights reserved. 2473-9529 8 9 14 May 2024 2024-05-14 2130-2132 2130 2132 10.1182/bloodadvances.2023011433 https://doi.org/10.1182/bloodadvances.2023011433 VoR 7.0 10.1182/bloodadvances.2023011433 noindex Elsevier 2024-05-07T03:32:01+05:30 2026-10-06T08:54:44+00:00 2026-10-06T08:54:44+00:00 True 1 https://www.elsevier.com/tdm/tdmrep-policy.json Acrobat Distiller 8.1.0 (Windows); modified using iTextSharp.LGPLv2.Core 3.7.4.0 uuid:b08de54b-8905-4e1d-b599-c574d56c0534 uuid:c7f1b95d-8a3c-4915-bbab-16d1864ae398 https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode Pages: Page: Label: 2130 Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 153, 603, 153, 605 Annotation: Subtype: Link Rect: 155, 606, 159, 615 Destination: 205 Annotation: Subtype: Link Rect: 161, 606, 165, 615 Destination: 205 Annotation: Subtype: Link Rect: 222, 603, 222, 605 Annotation: Subtype: Link Rect: 224, 606, 228, 615 Destination: 205 Annotation: Subtype: Link Rect: 230, 606, 234, 615 Destination: 205 Annotation: Subtype: Link Rect: 299, 603, 299, 605 Annotation: Subtype: Link Rect: 301, 606, 305, 615 Destination: 205 Annotation: Subtype: Link Rect: 362, 603, 362, 605 Annotation: Subtype: Link Rect: 364, 606, 368, 615 Destination: 205 Annotation: Subtype: Link Rect: 418, 603, 418, 605 Annotation: Subtype: Link Rect: 420, 606, 424, 615 Destination: 205 Annotation: Subtype: Link Rect: 485, 603, 485, 605 Annotation: Subtype: Link Rect: 487, 606, 491, 615 Destination: 205 Annotation: Subtype: Link Rect: 493, 606, 497, 615 Destination: 205 Annotation: Subtype: Link Rect: 80, 591, 80, 593 Annotation: Subtype: Link Rect: 80, 594, 84, 603 Destination: 205 Annotation: Subtype: Link Rect: 86, 594, 90, 603 Destination: 205 Annotation: Subtype: Link Rect: 249, 497, 253, 506 Destination: 59 Annotation: Subtype: Link Rect: 337, 475, 341, 484 Destination: 59 Annotation: Subtype: Link Rect: 479, 464, 483, 473 Destination: 59 Annotation: Subtype: Link Rect: 406, 426, 410, 435 Destination: 59 Annotation: Subtype: Link Rect: 411, 426, 415, 435 Destination: 59 Annotation: Subtype: Link Rect: 409, 393, 413, 402 Destination: 59 Annotation: Subtype: Link Rect: 451, 316, 455, 325 Destination: 59 Annotation: Subtype: Link Rect: 418, 300, 422, 309 Destination: 59 Annotation: Subtype: Link Rect: 515, 278, 519, 287 Destination: 59 Annotation: Subtype: Link Rect: 56, 86, 216, 93 Annotation: Subtype: Link Rect: 59, 66, 108, 73 Annotation: Subtype: Link Rect: 500, 104, 556, 111 Annotation: Subtype: Link Rect: 305, 95, 555, 102 Annotation: Subtype: Link Rect: 493, 762, 586, 782 Page: Label: 2131 Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 216, 279, 220, 288 Destination: 59 Annotation: Subtype: Link Rect: 111, 175, 115, 183 Destination: 59 Annotation: Subtype: Link Rect: 104, 142, 108, 151 Destination: 59 Annotation: Subtype: Link Rect: 308, 278, 340, 287 Destination: 16 Annotation: Subtype: Link Rect: 500, 215, 533, 224 Destination: 59 Annotation: Subtype: Link Rect: 461, 145, 465, 154 Destination: 59 Annotation: Subtype: Link Rect: 339, 79, 343, 88 Destination: 59 Page: Label: 2132 Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 415, 567, 505, 576 Annotation: Subtype: Link Rect: 533, 567, 556, 576 Annotation: Subtype: Link Rect: 305, 556, 372, 565 Annotation: Subtype: Link Rect: 409, 556, 499, 565 Annotation: Subtype: Link Rect: 533, 556, 556, 565 Annotation: Subtype: Link Rect: 305, 545, 372, 554 Annotation: Subtype: Link Rect: 396, 545, 486, 554 Annotation: Subtype: Link Rect: 510, 545, 556, 554 Annotation: Subtype: Link Rect: 305, 534, 349, 543 Annotation: Subtype: Link Rect: 305, 484, 369, 493 Annotation: Subtype: Link Rect: 318, 425, 534, 433 Annotation: Subtype: Link Rect: 318, 415, 556, 423 Annotation: Subtype: Link Rect: 318, 406, 525, 413 Annotation: Subtype: Link Rect: 318, 396, 457, 403 Annotation: Subtype: Link Rect: 318, 380, 510, 388 Annotation: Subtype: Link Rect: 318, 370, 556, 378 Annotation: Subtype: Link Rect: 318, 360, 541, 368 Annotation: Subtype: Link Rect: 318, 350, 357, 358 Annotation: Subtype: Link Rect: 318, 336, 556, 344 Annotation: Subtype: Link Rect: 318, 327, 542, 334 Annotation: Subtype: Link Rect: 318, 317, 555, 325 Annotation: Subtype: Link Rect: 318, 302, 530, 310 Annotation: Subtype: Link Rect: 318, 292, 542, 300 Annotation: Subtype: Link Rect: 318, 282, 484, 290 Annotation: Subtype: Link Rect: 318, 267, 548, 275 Annotation: Subtype: Link Rect: 318, 257, 554, 265 Annotation: Subtype: Link Rect: 318, 247, 505, 255 Annotation: Subtype: Link Rect: 318, 233, 556, 241 Annotation: Subtype: Link Rect: 318, 223, 548, 231 Annotation: Subtype: Link Rect: 318, 213, 544, 221 Annotation: Subtype: Link Rect: 318, 198, 543, 206 Annotation: Subtype: Link Rect: 318, 188, 525, 196 Annotation: Subtype: Link Rect: 318, 178, 556, 186 Annotation: Subtype: Link Rect: 318, 168, 444, 176 Annotation: Subtype: Link Rect: 318, 153, 538, 161 Annotation: Subtype: Link Rect: 318, 143, 556, 151 Annotation: Subtype: Link Rect: 318, 133, 547, 141 Annotation: Subtype: Link Rect: 318, 123, 547, 131 Annotation: Subtype: Link Rect: 318, 113, 504, 121 Checksum: fb681db8 Type: CRC32 Checksum: 3895fd549928a5a52ce356261eafaf9c Type: MD5 Checksum: 6060d975ab0ce5841df23ed72fc7929dcfcddf90 Type: SHA-1 Checksum: d52a317431d1e6e766a039592fc288f0b59b1d9c7295799fa86821541131bcb0 Type: SHA-256