15a933cc27548a7ab56761c4b243c08e pmc_10885955.pdf 60e1ca64ca3be0730512a639023863f0ffcd11f0 pmc_10885955.pdf a829a9fb505e5e620eb71b445aa8e54abcc2f2d3004350e53651dc45cf74bd88 pmc_10885955.pdf Title: Family Metacognitive Training (MCT-F): Adapting MCT to Mothers with Psychosis and Their Adolescent Children Subject: Over half of women with psychosis are mothers. Research suggests that mothers with psychosis face unique challenges affecting both their mental health prognosis and their relationship with their children. Moreover, those children have a higher risk of developing a mental disorder. Notwithstanding, interventions specifically tailored to these families remain largely uncovered. Metacognitive Training (MCT) has demonstrated its efficacy in improving cognitive insight, symptom management, and social cognition in people with psychosis. However, there is no evidence of the efficacy of MCT in a family setting (MCT-F). This study describes the first adaptation of MCT for mothers with psychosis and their adolescent children in an online group setting. The phases (assessment, decision, adaptation, production, topical experts’ integration) of the ADAPT-ITT model were systematically applied through a participatory approach (n = 22), including a first-person perspective and involving qualitative (e.g., topical expert literature review and consensus groups, interviews, thematic analyses) and quantitative methods. While MCT’s core components were retained, participants guided adaptations both in content and delivery. The findings suggest the importance of community engagement and sharing decision-making processes to demonstrate the acceptability and feasibility of the adapted intervention. Employing a structured approach such as the ADAPT-ITT model ensures readiness of the new training for efficacy trials. Keywords: mothers with psychosis; adolescents’ mental health; metacognitive training; ADAPT-ITT framework; family intervention Author: Victoria Espinosa, Paula Arin-González, Alba Jiménez-Lafuente, Nerea Pardo, Raquel López-Carrilero, Irene Birulés, Ana Barajas, Trinidad Pélaez, Luciana Díaz-Cutraro, Marina Verdaguer-Rodríguez, Alfonso Gutiérrez-Zotes, Carolina Palma-Sevillano, Paloma Varela-Casals, Miriam Salas-Sender, Ana Aznar, Rosa Ayesa-Arriola, Esther Pousa, Manuel Canal-Rivero, Nathalia Garrido-Torres, Clara Montserrat, Laura Muñoz-Lorenzo, Josep Maria Crosas and Susana Ochoa Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Tue Jan 30 10:26:16 2024 CET ModDate: Tue Jan 30 10:31:53 2024 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 18 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 747713 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- JDHVFZ+URWPalladioL-Bold Type 1 Custom yes yes no 10 0 TRPWLG+URWPalladioL-Roma Type 1 Custom yes yes no 15 0 MKNIVQ+URWPalladioL-Ital Type 1 Custom yes yes no 19 0 EKVCZD+VnURWPalladioL Type 1 Custom yes yes no 23 0 JYPLJJ+VnURWPalladioL-Bold Type 1 Custom yes yes no 28 0 WFRWYE+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 46 0 CMHBKB+TimesNewRoman,Italic CID TrueType Identity-H yes yes yes 95 0 CMGOPJ+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 101 0 CMGPAK+PalatinoLinotype CID TrueType Identity-H yes yes yes 104 0 CMGPAL+PalatinoLinotype TrueType WinAnsi yes yes no 110 0 CMGPAN+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 113 0 CMGPHL+PalatinoLinotype TrueType MacRoman yes yes no 116 0 CMHBJA+Arial CID TrueType Identity-H yes yes yes 119 0 SYVAVM+VnURWPalladioL-Italic Type 1 Custom yes yes no 153 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-03-08 02:36:01 CET RepresentationInformation: pmc_10885955.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-03-05 02:33:40 CET Size: 747713 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 361 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: section.1 Item: Title: Materials and Methods Destination: section.2 Children: Item: Title: Design Destination: subsection.2.1 Item: Title: Participants Destination: subsection.2.2 Item: Title: Measures Destination: subsection.2.3 Item: Title: Procedure Destination: subsection.2.4 Children: Item: Title: Step 1: Assessment Destination: subsubsection.2.4.1 Item: Title: Step 2: Decision Destination: subsubsection.2.4.2 Item: Title: Step 3: Administration Destination: subsubsection.2.4.3 Item: Title: Step 4: Production Destination: subsubsection.2.4.4 Item: Title: Step 5: Topical Experts Destination: subsubsection.2.4.5 Item: Title: Step 6: Integration Destination: subsubsection.2.4.6 Item: Title: Steps 7 and 8: Training and Testing Destination: subsubsection.2.4.7 Item: Title: Data Analysis Destination: subsubsection.2.4.8 Item: Title: Results Destination: section.3 Children: Item: Title: Step 1: Assessment of Needs and Different Intervention Options Destination: subsection.3.1 Item: Title: Step 2: Decision Destination: subsection.3.2 Item: Title: Step 3: Administration Destination: subsection.3.3 Item: Title: Step 4: Production Destination: subsection.3.4 Item: Title: Step 5: Topical Experts Destination: subsection.3.5 Item: Title: Step 6: Integration Destination: subsection.3.6 Item: Title: Discussion Destination: section.4 Item: Title: Conclusions Destination: section.5 Item: Title: References Destination: section.6 Info: Title: Family Metacognitive Training (MCT-F): Adapting MCT to Mothers with Psychosis and Their Adolescent Children Author: Victoria Espinosa, Paula Arin-González, Alba Jiménez-Lafuente, Nerea Pardo, Raquel López-Carrilero, Irene Birulés, Ana Barajas, Trinidad Pélaez, Luciana Díaz-Cutraro, Marina Verdaguer-Rodríguez, Alfonso Gutiérrez-Zotes, Carolina Palma-Sevillano, Paloma Varela-Casals, Miriam Salas-Sender, Ana Aznar, Rosa Ayesa-Arriola, Esther Pousa, Manuel Canal-Rivero, Nathalia Garrido-Torres, Clara Montserrat, Laura Muñoz-Lorenzo, Josep Maria Crosas and Susana Ochoa Subject: Over half of women with psychosis are mothers. Research suggests that mothers with psychosis face unique challenges affecting both their mental health prognosis and their relationship with their children. Moreover, those children have a higher risk of developing a mental disorder. Notwithstanding, interventions specifically tailored to these families remain largely uncovered. Metacognitive Training (MCT) has demonstrated its efficacy in improving cognitive insight, symptom management, and social cognition in people with psychosis. However, there is no evidence of the efficacy of MCT in a family setting (MCT-F). This study describes the first adaptation of MCT for mothers with psychosis and their adolescent children in an online group setting. The phases (assessment, decision, adaptation, production, topical experts’ integration) of the ADAPT-ITT model were systematically applied through a participatory approach (n = 22), including a first-person perspective and involving qualitative (e.g., topical expert literature review and consensus groups, interviews, thematic analyses) and quantitative methods. While MCT’s core components were retained, participants guided adaptations both in content and delivery. The findings suggest the importance of community engagement and sharing decision-making processes to demonstrate the acceptability and feasibility of the adapted intervention. Employing a structured approach such as the ADAPT-ITT model ensures readiness of the new training for efficacy trials. 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