2bd1f94fd6587bbe80371a41803f2c46  pmc_10903926.pdf
8f3ab375ed020d67d8cc6669829f9177af493048  pmc_10903926.pdf
410671d0140b7be5c5cf111b601f0f671b8c2a39ad307f67c9d4416ec4b72331  pmc_10903926.pdf

Creator:         Adobe InDesign 16.0 (Windows)
Producer:        Adobe PDF Library 15.0
CreationDate:    Mon Mar 18 12:08:42 2024 CET
ModDate:         Mon Mar 18 12:08:47 2024 CET
Custom Metadata: no
Metadata Stream: yes
Tagged:          yes
UserProperties:  no
Suspects:        no
Form:            none
JavaScript:      no
Pages:           12
Encrypted:       no
Page size:       595.276 x 793.701 pts
Page rot:        0
File size:       2181863 bytes
Optimized:       yes
PDF version:     1.7


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
NAFRPY+BerkeleyStd-Bold              Type 1C           WinAnsi          yes yes yes   1458  0
RJCKTQ+BerkeleyStd-Book              Type 1C           Custom           yes yes yes   1459  0
CRUIWU+Calibri                       TrueType          WinAnsi          yes yes yes   1460  0
TBJGAM+Calibri-Bold                  TrueType          WinAnsi          yes yes yes   1461  0
IIUSCI+CopperplateGothic-Light       TrueType          WinAnsi          yes yes yes   1462  0
CLHQGU+CentabelBook                  TrueType          WinAnsi          yes yes yes   1463  0
ZOYRBA+TimesNewRomanPSMT             TrueType          WinAnsi          yes yes yes   1486  0
CLHQGU+CentabelBook                  TrueType          WinAnsi          yes yes yes   1529  0
ZPTMQA+Calibri-Light                 TrueType          WinAnsi          yes yes yes    118  0
CLHQGU+CentabelBook                  TrueType          WinAnsi          yes yes yes     57  0
KTFQOE+Calibri-Bold                  CID TrueType      Identity-H       yes yes yes    160  0
CLHQGU+CentabelBook                  TrueType          WinAnsi          yes yes yes    127  0
UELNJK+BerkeleyStd-BookItalic        Type 1C           WinAnsi          yes yes yes    172  0
VGUOXI+BerkeleyStd-Black             Type 1C           WinAnsi          yes yes yes    267  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2024-04-27 02:35:01 CEST
 RepresentationInformation: pmc_10903926.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2024-04-24 02:34:29 CEST
  Size: 2181863
  Format: PDF
  Version: 1.7
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: Linearized PDF
  PDFMetadata: 
   Objects: 1539
   FreeObjects: 911
   IncrementalUpdates: 1
   DocumentCatalog: 
    ViewerPreferences: 
     HideToolbar: false
     HideMenubar: false
     HideWindowUI: false
     FitWindow: false
     CenterWindow: false
     DisplayDocTitle: false
     NonFullScreenPageMode: UseNone
     Direction: L2R
     ViewArea: CropBox
     ViewClip: CropBox
     PrintArea: CropBox
     PageClip: CropBox
    PageLayout: SinglePage
    PageMode: UseNone
    Language: en-GB
   Info: 
    Creator: Adobe InDesign 16.0 (Windows)
    Producer: Adobe PDF Library 15.0
    CreationDate: Mon Mar 18 12:08:42 CET 2024
    ModDate: Mon Mar 18 12:08:47 CET 2024
   ID: 0xbbf093b4a8567e4a8c29b4f0e17e4dfa, 0x0224b86ac233fa4bb66026274f952f5c
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 42
      ImageHeight: 32
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1167
      ImageHeight: 793
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Decode: 0, 255
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 2524
      ImageHeight: 2442
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1772
      ImageHeight: 1036
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
   Fonts: 
    Type1: 
     Font: 
      BaseFont: NAFRPY+BerkeleyStd-Bold
      FontSubset: true
      FirstChar: 32
      LastChar: 121
      FontDescriptor: 
       FontName: NAFRPY+BerkeleyStd-Bold
       Flags: Serif, Nonsymbolic
       FontBBox: -102, -250, 1129, 847
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: RJCKTQ+BerkeleyStd-Book
      FontSubset: true
      FirstChar: 31
      LastChar: 252
      FontDescriptor: 
       FontName: RJCKTQ+BerkeleyStd-Book
       Flags: Serif, Nonsymbolic
       FontBBox: -86, -256, 1062, 850
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: VGUOXI+BerkeleyStd-Black
      FontSubset: true
      FirstChar: 32
      LastChar: 57
      FontDescriptor: 
       FontName: VGUOXI+BerkeleyStd-Black
       Flags: Serif, Nonsymbolic
       FontBBox: -117, -250, 1172, 844
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: UELNJK+BerkeleyStd-BookItalic
      FontSubset: true
      FirstChar: 32
      LastChar: 146
      FontDescriptor: 
       FontName: UELNJK+BerkeleyStd-BookItalic
       Flags: Serif, Nonsymbolic, Italic
       FontBBox: -144, -260, 1016, 853
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
    TrueType: 
     Font: 
      BaseFont: CRUIWU+Calibri
      FontSubset: true
      FirstChar: 32
      LastChar: 149
      FontDescriptor: 
       FontName: CRUIWU+Calibri
       Flags: Nonsymbolic
       FontBBox: -503, -312, 1240, 1026
       FontFile2: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: TBJGAM+Calibri-Bold
      FontSubset: true
      FirstChar: 32
      LastChar: 117
      FontDescriptor: 
       FontName: TBJGAM+Calibri-Bold
       Flags: Nonsymbolic
       FontBBox: -519, -349, 1263, 1039
       FontFile2: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: IIUSCI+CopperplateGothic-Light
      FontSubset: true
      FirstChar: 32
      LastChar: 149
      FontDescriptor: 
       FontName: IIUSCI+CopperplateGothic-Light
       Flags: Serif, Nonsymbolic, SmallCap
       FontBBox: -100, -250, 1279, 872
       FontFile2: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: CLHQGU+CentabelBook
      FontSubset: true
      FirstChar: 32
      LastChar: 232
      FontDescriptor: 
       FontName: CLHQGU+CentabelBook
       Flags: Serif, Nonsymbolic
       FontBBox: -167, -210, 1000, 925
       FontFile2: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: ZOYRBA+TimesNewRomanPSMT
      FontSubset: true
      FirstChar: 32
      LastChar: 32
      FontDescriptor: 
       FontName: ZOYRBA+TimesNewRomanPSMT
       Flags: Serif, Nonsymbolic
       FontBBox: -568, -307, 2046, 1040
       FontFile2: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 6.0-c002 79.164488, 2020/07/10-22:06:53        ">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:xmp="http://ns.adobe.com/xap/1.0/"
            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/"
            xmlns:stRef="http://ns.adobe.com/xap/1.0/sType/ResourceRef#"
            xmlns:stEvt="http://ns.adobe.com/xap/1.0/sType/ResourceEvent#"
            xmlns:dc="http://purl.org/dc/elements/1.1/"
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <xmp:CreateDate>2024-03-18T12:08:42+01:00</xmp:CreateDate>
         <xmp:MetadataDate>2024-03-18T12:08:47+01:00</xmp:MetadataDate>
         <xmp:ModifyDate>2024-03-18T12:08:47+01:00</xmp:ModifyDate>
         <xmp:CreatorTool>Adobe InDesign 16.0 (Windows)</xmp:CreatorTool>
         <xmpMM:InstanceID>uuid:210a4bf3-338b-48c2-a84e-dfa4aecc7bb1</xmpMM:InstanceID>
         <xmpMM:OriginalDocumentID>xmp.did:1bdb6a01-f7f3-fb4d-b297-acf958840ec1</xmpMM:OriginalDocumentID>
         <xmpMM:DocumentID>xmp.id:e22a2af2-32d1-d441-b7e9-2a03b57c5240</xmpMM:DocumentID>
         <xmpMM:RenditionClass>proof:pdf</xmpMM:RenditionClass>
         <xmpMM:DerivedFrom rdf:parseType="Resource">
            <stRef:instanceID>xmp.iid:6bef7f99-989e-3549-b88f-f5c9917c4287</stRef:instanceID>
            <stRef:documentID>xmp.did:23de615b-6372-d34a-be82-682eb643c3d5</stRef:documentID>
            <stRef:originalDocumentID>xmp.did:1bdb6a01-f7f3-fb4d-b297-acf958840ec1</stRef:originalDocumentID>
            <stRef:renditionClass>default</stRef:renditionClass>
         </xmpMM:DerivedFrom>
         <xmpMM:History>
            <rdf:Seq>
               <rdf:li rdf:parseType="Resource">
                  <stEvt:action>converted</stEvt:action>
                  <stEvt:parameters>from application/x-indesign to application/pdf</stEvt:parameters>
                  <stEvt:softwareAgent>Adobe InDesign 16.0 (Windows)</stEvt:softwareAgent>
                  <stEvt:changed>/</stEvt:changed>
                  <stEvt:when>2024-03-18T12:08:42+01:00</stEvt:when>
               </rdf:li>
            </rdf:Seq>
         </xmpMM:History>
         <dc:format>application/pdf</dc:format>
         <pdf:Producer>Adobe PDF Library 15.0</pdf:Producer>
         <pdf:Trapped>False</pdf:Trapped>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 559, 590, 591, 575
      Annotation: 
       Subtype: Link
       Rect: 135, 535, 149, 521
      Annotation: 
       Subtype: Link
       Rect: 127, 450, 141, 436
      Annotation: 
       Subtype: Link
       Rect: 240, 450, 254, 436
      Annotation: 
       Subtype: Link
       Rect: 115, 436, 129, 422
      Annotation: 
       Subtype: Link
       Rect: 216, 436, 230, 422
      Annotation: 
       Subtype: Link
       Rect: 129, 422, 143, 408
      Annotation: 
       Subtype: Link
       Rect: 212, 422, 225, 408
      Annotation: 
       Subtype: Link
       Rect: 166, 407, 180, 394
      Annotation: 
       Subtype: Link
       Rect: 90, 393, 104, 379
      Annotation: 
       Subtype: Link
       Rect: 234, 393, 248, 379
      Annotation: 
       Subtype: Link
       Rect: 137, 379, 151, 365
      Annotation: 
       Subtype: Link
       Rect: 213, 379, 227, 365
      Annotation: 
       Subtype: Link
       Rect: 146, 365, 160, 351
      Annotation: 
       Subtype: Link
       Rect: 222, 365, 235, 351
      Annotation: 
       Subtype: Link
       Rect: 157, 351, 171, 337
      Annotation: 
       Subtype: Link
       Rect: 100, 337, 114, 323
      Annotation: 
       Subtype: Link
       Rect: 128, 322, 142, 308
      Annotation: 
       Subtype: Link
       Rect: 232, 322, 246, 308
      Annotation: 
       Subtype: Link
       Rect: 122, 180, 135, 167
      Annotation: 
       Subtype: Link
       Rect: 218, 180, 232, 167
     Thumb: true
    Page: 
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 415, 716, 420, 705
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 173, 673, 178, 662
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 181, 673, 185, 662
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 116, 661, 121, 650
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 462, 661, 467, 650
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 472, 661, 477, 650
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 313, 625, 318, 614
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 363, 600, 368, 589
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 388, 570, 393, 559
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 248, 522, 258, 511
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 263, 522, 273, 511
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 491, 492, 501, 481
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 503, 492, 513, 481
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 174, 467, 184, 456
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 115, 455, 125, 444
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 233, 418, 243, 407
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 248, 418, 258, 407
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 439, 376, 449, 365
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 454, 376, 464, 365
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 145, 352, 155, 341
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 160, 352, 170, 341
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 221, 315, 231, 304
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 478, 291, 489, 280
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 494, 291, 504, 280
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 202, 158, 212, 147
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 158, 133, 168, 122
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 170, 133, 180, 122
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 183, 133, 192, 122
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 264, 133, 405, 122
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 224, 121, 233, 110
       ActionDest: 49
     Thumb: true
    Page: 
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 290, 540, 300, 529
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 375, 528, 385, 517
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 349, 503, 359, 492
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 494, 479, 547, 468
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 121, 467, 217, 456
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 204, 454, 214, 443
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 244, 413, 253, 402
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 326, 401, 336, 390
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 202, 334, 212, 323
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 235, 334, 378, 323
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 379, 256, 389, 245
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 396, 207, 406, 196
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 461, 207, 471, 196
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 346, 183, 489, 172
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 357, 158, 367, 147
       ActionDest: 49
     Thumb: true
    Page: 
     Sequence: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 410, 651, 445, 640
       ActionDest: 7
      Annotation: 
       Subtype: Link
       Rect: 486, 441, 516, 430
       ActionDest: 7
      Annotation: 
       Subtype: Link
       Rect: 315, 405, 458, 393
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 464, 303, 499, 292
       ActionDest: 20
     Thumb: true
    Page: 
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 274, 104, 310, 93
       ActionDest: 28
     Thumb: true
    Page: 
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 390, 183, 425, 172
       ActionDest: 20
      Annotation: 
       Subtype: Link
       Rect: 411, 72, 420, 61
       ActionDest: 49
     Thumb: true
    Page: 
     Sequence: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 511, 602, 521, 591
       ActionDest: 52
      Annotation: 
       Subtype: Link
       Rect: 490, 511, 500, 500
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 306, 486, 315, 475
       ActionDest: 52
      Annotation: 
       Subtype: Link
       Rect: 492, 444, 503, 433
       ActionDest: 52
      Annotation: 
       Subtype: Link
       Rect: 194, 389, 203, 378
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 326, 298, 358, 287
       ActionDest: 7
      Annotation: 
       Subtype: Link
       Rect: 348, 262, 358, 251
       ActionDest: 49
      Annotation: 
       Subtype: Link
       Rect: 360, 262, 370, 251
       ActionDest: 52
      Annotation: 
       Subtype: Link
       Rect: 207, 183, 217, 172
       ActionDest: 52
      Annotation: 
       Subtype: Link
       Rect: 420, 183, 431, 172
       ActionDest: 52
      Annotation: 
       Subtype: Link
       Rect: 436, 183, 446, 172
       ActionDest: 52
      Annotation: 
       Subtype: Link
       Rect: 224, 171, 235, 160
       ActionDest: 52
      Annotation: 
       Subtype: Link
       Rect: 240, 171, 250, 160
       ActionDest: 52
      Annotation: 
       Subtype: Link
       Rect: 207, 134, 216, 123
       ActionDest: 52
      Annotation: 
       Subtype: Link
       Rect: 328, 104, 338, 93
       ActionDest: 52
      Annotation: 
       Subtype: Link
       Rect: 341, 104, 350, 93
       ActionDest: 52
     Thumb: true
    Page: 
     Sequence: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 116, 752, 126, 741
       ActionDest: 52
      Annotation: 
       Subtype: Link
       Rect: 129, 752, 139, 741
       ActionDest: 52
      Annotation: 
       Subtype: Link
       Rect: 116, 740, 126, 729
       ActionDest: 52
      Annotation: 
       Subtype: Link
       Rect: 128, 740, 138, 729
       ActionDest: 52
      Annotation: 
       Subtype: Link
       Rect: 508, 710, 517, 699
       ActionDest: 52
      Annotation: 
       Subtype: Link
       Rect: 523, 710, 533, 699
       ActionDest: 52
      Annotation: 
       Subtype: Link
       Rect: 141, 662, 150, 651
       ActionDest: 42
      Annotation: 
       Subtype: Link
       Rect: 439, 494, 449, 483
       ActionDest: 52
      Annotation: 
       Subtype: Link
       Rect: 518, 374, 528, 363
       ActionDest: 52
     Thumb: true
    Page: 
     Sequence: 9
     Thumb: true
    Page: 
     Sequence: 10
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 112, 523, 235, 513
      Annotation: 
       Subtype: Link
       Rect: 397, 464, 538, 454
      Annotation: 
       Subtype: Link
       Rect: 100, 453, 290, 443
      Annotation: 
       Subtype: Link
       Rect: 155, 431, 226, 421
      Annotation: 
       Subtype: Link
       Rect: 229, 431, 349, 421
      Annotation: 
       Subtype: Link
       Rect: 471, 420, 538, 410
      Annotation: 
       Subtype: Link
       Rect: 100, 409, 239, 399
      Annotation: 
       Subtype: Link
       Rect: 380, 398, 538, 388
      Annotation: 
       Subtype: Link
       Rect: 100, 387, 521, 377
      Annotation: 
       Subtype: Link
       Rect: 346, 353, 417, 343
      Annotation: 
       Subtype: Link
       Rect: 419, 353, 537, 343
      Annotation: 
       Subtype: Link
       Rect: 243, 331, 313, 321
      Annotation: 
       Subtype: Link
       Rect: 315, 331, 433, 321
      Annotation: 
       Subtype: Link
       Rect: 111, 298, 182, 288
      Annotation: 
       Subtype: Link
       Rect: 184, 298, 308, 288
      Annotation: 
       Subtype: Link
       Rect: 452, 276, 524, 266
      Annotation: 
       Subtype: Link
       Rect: 226, 254, 297, 244
      Annotation: 
       Subtype: Link
       Rect: 299, 254, 419, 244
      Annotation: 
       Subtype: Link
       Rect: 385, 232, 454, 222
      Annotation: 
       Subtype: Link
       Rect: 456, 232, 538, 222
      Annotation: 
       Subtype: Link
       Rect: 420, 210, 491, 200
      Annotation: 
       Subtype: Link
       Rect: 493, 210, 538, 200
      Annotation: 
       Subtype: Link
       Rect: 100, 199, 182, 189
      Annotation: 
       Subtype: Link
       Rect: 517, 177, 538, 167
      Annotation: 
       Subtype: Link
       Rect: 100, 166, 153, 156
      Annotation: 
       Subtype: Link
       Rect: 155, 166, 275, 156
      Annotation: 
       Subtype: Link
       Rect: 468, 155, 538, 145
      Annotation: 
       Subtype: Link
       Rect: 99, 144, 240, 134
      Annotation: 
       Subtype: Link
       Rect: 150, 111, 222, 101
      Annotation: 
       Subtype: Link
       Rect: 224, 111, 326, 101
      Annotation: 
       Subtype: Link
       Rect: 317, 78, 536, 68
     Thumb: true
    Page: 
     Sequence: 11
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 115, 730, 185, 720
      Annotation: 
       Subtype: Link
       Rect: 187, 730, 314, 720
      Annotation: 
       Subtype: Link
       Rect: 425, 708, 496, 698
      Annotation: 
       Subtype: Link
       Rect: 498, 708, 547, 698
      Annotation: 
       Subtype: Link
       Rect: 108, 697, 184, 687
      Annotation: 
       Subtype: Link
       Rect: 224, 675, 294, 665
      Annotation: 
       Subtype: Link
       Rect: 296, 675, 399, 665
      Annotation: 
       Subtype: Link
       Rect: 169, 641, 327, 631
      Annotation: 
       Subtype: Link
       Rect: 123, 608, 194, 598
      Annotation: 
       Subtype: Link
       Rect: 196, 608, 297, 598
      Annotation: 
       Subtype: Link
       Rect: 475, 586, 547, 576
      Annotation: 
       Subtype: Link
       Rect: 108, 575, 193, 565
      Annotation: 
       Subtype: Link
       Rect: 525, 553, 547, 543
      Annotation: 
       Subtype: Link
       Rect: 108, 542, 161, 532
      Annotation: 
       Subtype: Link
       Rect: 163, 542, 269, 532
      Annotation: 
       Subtype: Link
       Rect: 430, 520, 500, 510
      Annotation: 
       Subtype: Link
       Rect: 502, 520, 547, 510
      Annotation: 
       Subtype: Link
       Rect: 108, 509, 200, 499
      Annotation: 
       Subtype: Link
       Rect: 425, 487, 496, 477
      Annotation: 
       Subtype: Link
       Rect: 498, 487, 547, 477
      Annotation: 
       Subtype: Link
       Rect: 108, 476, 181, 466
      Annotation: 
       Subtype: Link
       Rect: 387, 454, 458, 444
      Annotation: 
       Subtype: Link
       Rect: 460, 454, 546, 444
      Annotation: 
       Subtype: Link
       Rect: 474, 409, 547, 399
      Annotation: 
       Subtype: Link
       Rect: 108, 398, 221, 388
      Annotation: 
       Subtype: Link
       Rect: 547, 376, 547, 366
      Annotation: 
       Subtype: Link
       Rect: 108, 365, 177, 355
      Annotation: 
       Subtype: Link
       Rect: 179, 365, 300, 355
      Annotation: 
       Subtype: Link
       Rect: 337, 343, 407, 333
      Annotation: 
       Subtype: Link
       Rect: 410, 343, 485, 333
      Annotation: 
       Subtype: Link
       Rect: 391, 321, 462, 311
      Annotation: 
       Subtype: Link
       Rect: 464, 321, 546, 311
      Annotation: 
       Subtype: Link
       Rect: 200, 288, 338, 278
      Annotation: 
       Subtype: Link
       Rect: 346, 266, 417, 256
      Annotation: 
       Subtype: Link
       Rect: 419, 266, 541, 256
      Annotation: 
       Subtype: Link
       Rect: 399, 244, 470, 234
      Annotation: 
       Subtype: Link
       Rect: 473, 244, 547, 234
      Annotation: 
       Subtype: Link
       Rect: 108, 232, 150, 223
      Annotation: 
       Subtype: Link
       Rect: 397, 221, 547, 211
      Annotation: 
       Subtype: Link
       Rect: 108, 210, 247, 200
      Annotation: 
       Subtype: Link
       Rect: 521, 199, 547, 189
      Annotation: 
       Subtype: Link
       Rect: 108, 188, 349, 178
      Annotation: 
       Subtype: Link
       Rect: 476, 166, 547, 156
      Annotation: 
       Subtype: Link
       Rect: 108, 155, 236, 145
      Annotation: 
       Subtype: Link
       Rect: 258, 144, 385, 134
      Annotation: 
       Subtype: Link
       Rect: 413, 133, 547, 123
      Annotation: 
       Subtype: Link
       Rect: 108, 122, 123, 112
      Annotation: 
       Subtype: Link
       Rect: 359, 111, 547, 101
      Annotation: 
       Subtype: Link
       Rect: 108, 100, 235, 90
      Annotation: 
       Subtype: Link
       Rect: 472, 78, 547, 68
      Annotation: 
       Subtype: Link
       Rect: 108, 67, 225, 57
     Thumb: true
    Page: 
     Sequence: 12
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 416, 741, 487, 731
      Annotation: 
       Subtype: Link
       Rect: 489, 741, 538, 731
      Annotation: 
       Subtype: Link
       Rect: 100, 730, 174, 720
      Annotation: 
       Subtype: Link
       Rect: 226, 697, 297, 687
      Annotation: 
       Subtype: Link
       Rect: 299, 697, 420, 687
      Annotation: 
       Subtype: Link
       Rect: 219, 664, 290, 654
      Annotation: 
       Subtype: Link
       Rect: 292, 664, 413, 654
      Annotation: 
       Subtype: Link
       Rect: 419, 641, 490, 631
      Annotation: 
       Subtype: Link
       Rect: 493, 641, 538, 631
      Annotation: 
       Subtype: Link
       Rect: 100, 630, 180, 620
      Annotation: 
       Subtype: Link
       Rect: 360, 619, 538, 609
      Annotation: 
       Subtype: Link
       Rect: 100, 608, 115, 598
      Annotation: 
       Subtype: Link
       Rect: 430, 597, 538, 587
      Annotation: 
       Subtype: Link
       Rect: 99, 586, 309, 576
      Annotation: 
       Subtype: Link
       Rect: 138, 553, 209, 543
      Annotation: 
       Subtype: Link
       Rect: 211, 553, 329, 543
      Annotation: 
       Subtype: Link
       Rect: 420, 531, 491, 521
      Annotation: 
       Subtype: Link
       Rect: 493, 531, 538, 521
      Annotation: 
       Subtype: Link
       Rect: 100, 520, 174, 510
      Annotation: 
       Subtype: Link
       Rect: 270, 476, 342, 466
      Annotation: 
       Subtype: Link
       Rect: 345, 476, 460, 466
      Annotation: 
       Subtype: Link
       Rect: 333, 454, 403, 444
      Annotation: 
       Subtype: Link
       Rect: 405, 454, 502, 444
      Annotation: 
       Subtype: Link
       Rect: 371, 431, 444, 421
      Annotation: 
       Subtype: Link
       Rect: 447, 431, 538, 421
      Annotation: 
       Subtype: Link
       Rect: 100, 420, 130, 410
      Annotation: 
       Subtype: Link
       Rect: 275, 398, 346, 388
      Annotation: 
       Subtype: Link
       Rect: 348, 398, 457, 388
      Annotation: 
       Subtype: Link
       Rect: 468, 376, 538, 366
      Annotation: 
       Subtype: Link
       Rect: 100, 365, 205, 355
      Annotation: 
       Subtype: Link
       Rect: 467, 343, 538, 333
      Annotation: 
       Subtype: Link
       Rect: 100, 332, 168, 322
      Annotation: 
       Subtype: Link
       Rect: 111, 299, 182, 289
      Annotation: 
       Subtype: Link
       Rect: 184, 299, 299, 289
      Annotation: 
       Subtype: Link
       Rect: 464, 288, 538, 278
      Annotation: 
       Subtype: Link
       Rect: 100, 277, 267, 267
      Annotation: 
       Subtype: Link
       Rect: 289, 244, 359, 234
      Annotation: 
       Subtype: Link
       Rect: 362, 244, 496, 234
      Annotation: 
       Subtype: Link
       Rect: 238, 199, 308, 189
      Annotation: 
       Subtype: Link
       Rect: 310, 199, 415, 189
      Annotation: 
       Subtype: Link
       Rect: 269, 155, 449, 145
      Annotation: 
       Subtype: Link
       Rect: 538, 133, 538, 123
      Annotation: 
       Subtype: Link
       Rect: 100, 122, 167, 112
      Annotation: 
       Subtype: Link
       Rect: 169, 122, 284, 112
      Annotation: 
       Subtype: Link
       Rect: 292, 100, 499, 90
      Annotation: 
       Subtype: Link
       Rect: 415, 78, 485, 68
     Thumb: true
  Checksum: 5dec396c
   Type: CRC32
  Checksum: 2bd1f94fd6587bbe80371a41803f2c46
   Type: MD5
  Checksum: 8f3ab375ed020d67d8cc6669829f9177af493048
   Type: SHA-1
  Checksum: 410671d0140b7be5c5cf111b601f0f671b8c2a39ad307f67c9d4416ec4b72331
   Type: SHA-256