109910392559d7d5f1cfb9e04ab59433 pmc_10952043.pdf b07c24b01bee8021b52067524b70da3f591f427c pmc_10952043.pdf c27791b64ae7d0b5aca9b946c2b063eba98d30a3c7da002eafa7766954c9dc55 pmc_10952043.pdf Creator: Arbortext Advanced Print Publisher 9.1.510/W Unicode Producer: Acrobat Distiller 7.0 (Windows) CreationDate: Tue Mar 5 14:17:24 2024 CET ModDate: Tue Mar 5 14:17:24 2024 CET Custom Metadata: no Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 18 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 2503934 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- LAACHB+AdvOTd3a5f740 Type 1C WinAnsi yes yes no 1383 0 LAACHC+AdvOTd3a5f740+fb Type 1C Custom yes yes yes 1384 0 LAACHD+AdvOT9b12cd41 Type 1C WinAnsi yes yes no 1385 0 LAACIE+AdvOT9b12cd41+20 Type 1C WinAnsi yes yes no 1386 0 LAACIF+AdvOT9b12cd41+fb Type 1C Custom yes yes yes 1387 0 LAACJG+AdvOT2c8ce45a Type 1C WinAnsi yes yes no 1388 0 LAACJH+AdvOT1ef757c0 Type 1C WinAnsi yes yes no 1389 0 LAACJI+AdvOT7d6df7ab.I Type 1C WinAnsi yes yes no 1390 0 LAACJJ+AdvOT1ef757c0+fb Type 1C Custom yes yes yes 1391 0 LAADFF+AdvOTd168d80a.I Type 1C WinAnsi yes yes no 1392 0 LAADPC+AdvOT1ef757c0+20 Type 1C WinAnsi yes yes no 1402 0 LAAECC+AdvOT310e2d14+03 Type 1C Custom yes yes yes 1405 0 LAAMHA+AdvOT310e2d14+20 Type 1C Custom yes yes yes 1406 0 LAAMHB+AdvOT1ef757c0+22 Type 1C Custom yes yes no 1407 0 LAAMKB+AdvOT7d6df7ab.I+22 Type 1C Custom yes yes no 1408 0 LAAMKC+AdvOTd3a5f740+20 Type 1C WinAnsi yes yes no 1409 0 LABKOL+AdvPSSym Type 1C WinAnsi yes yes no 1421 0 LABLEK+AdvOTc8b77491.I Type 1C WinAnsi yes yes no 1429 0 LABLEL+AdvOT46dcae81 Type 1C WinAnsi yes yes no 1430 0 LABPPP+AdvOT7d6df7ab.I+fb Type 1C Custom yes yes yes 1432 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-02-17 16:55:32 CET RepresentationInformation: pmc_10952043.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-02-13 02:31:41 CET Size: 2503934 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 1563 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: MYC: there is more to it than cancer Destination: titlink1 Children: Item: Title: 1 Discovery and initial characterisation of MYC Destination: flink1 Item: Title: 2 Physiological processes mediated by MYC Destination: flink2 Children: Item: Title: 2.1 Proliferation Destination: slink1 Item: Title: 2.2 Differentiation Destination: slink2 Item: Title: 2.3 Ribosome biogenesis and protein translation Destination: slink3 Item: Title: 2.4 Metabolism and mitochondrial biogenesis Destination: slink4 Item: Title: 2.5 Development Destination: slink5 Children: Item: Title: 2.5.1 Pancreas Destination: sslink1 Item: Title: 2.5.2 Bone Destination: sslink2 Item: Title: 2.5.3 Vascular development Destination: sslink3 Item: Title: 3 Physiological MYC functions hijacked by tumour cells Destination: flink3 Item: Title: 4 MYC’s involvement in diseases and conditions Destination: flink4 Children: Item: Title: 4.1 Metabolic diseases Destination: slink6 Item: Title: 4.2 Polycystic kidney disease Destination: slink7 Item: Title: 4.3 Multiple sclerosis Destination: slink8 Item: Title: 4.4 Aging Destination: slink9 Item: Title: 4.5 Cardiac metabolism after pathological stress Destination: slink10 Item: Title: 4.6 Restenosis Destination: slink11 Item: Title: 4.7 Bone developmental disorders Destination: slink12 Item: Title: 4.8 Potential role of MYC in other diseases and conditions Destination: slink13 Item: Title: 5 Current state of MYC inhibition in the clinical setting Destination: flink5 Item: Title: 6 Possibilities to activate or express MYC Destination: flink6 Item: Title: 7 Perspective Destination: flink7 Item: Title: Author contributions Destination: flink8 Item: Title: Funding Destination: flink9 Item: Title: Acknowledgments Destination: slink14 Item: Title: Conflict of interest Destination: flink10 Item: Title: Publisher’s note Destination: flink11 Item: Title: References Destination: rlink1 Info: Creator: Arbortext Advanced Print Publisher 9.1.510/W Unicode Producer: Acrobat Distiller 7.0 (Windows) CreationDate: Tue Mar 05 14:47:24 CET 2024 ModDate: Tue Mar 05 14:47:24 CET 2024 ID: 0x03bbab2aa55ccb6e0efb40baf914a686, 0x855d8bc43f92fc429c5686bdb28daf66 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1799 ImageHeight: 1778 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1978 ImageHeight: 466 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1783 ImageHeight: 2329 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 59 ImageHeight: 68 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 59 ImageHeight: 61 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 55 ImageHeight: 57 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 60 ImageHeight: 69 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 59 ImageHeight: 66 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 59 ImageHeight: 68 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 55 ImageHeight: 56 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 57 ImageHeight: 66 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 59 ImageHeight: 68 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 59 ImageHeight: 66 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 59 ImageHeight: 66 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 56 ImageHeight: 61 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 59 ImageHeight: 59 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 59 ImageHeight: 62 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 59 ImageHeight: 65 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 56 ImageHeight: 68 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1899 ImageHeight: 746 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Fonts: Type1: Font: BaseFont: LAAMKB+AdvOT7d6df7ab.I+22 FontSubset: true FirstChar: 21 LastChar: 21 FontDescriptor: FontName: LAAMKB+AdvOT7d6df7ab.I+22 Flags: Nonsymbolic FontBBox: -156, -166, 750, 916 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: LAAMKC+AdvOTd3a5f740+20 FontSubset: true FirstChar: 146 LastChar: 146 FontDescriptor: FontName: LAAMKC+AdvOTd3a5f740+20 Flags: Nonsymbolic FontBBox: -114, -166, 1062, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAACHB+AdvOTd3a5f740 FontSubset: true FirstChar: 42 LastChar: 237 FontDescriptor: FontName: LAACHB+AdvOTd3a5f740 Flags: Nonsymbolic FontBBox: -52, -208, 916, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAACHC+AdvOTd3a5f740+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: LAACHC+AdvOTd3a5f740+fb Flags: Symbolic FontBBox: 0, 0, 906, 708 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: LAACHD+AdvOT9b12cd41 FontSubset: true FirstChar: 40 LastChar: 243 FontDescriptor: FontName: LAACHD+AdvOT9b12cd41 Flags: Nonsymbolic FontBBox: -52, -208, 906, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAACIE+AdvOT9b12cd41+20 FontSubset: true FirstChar: 146 LastChar: 148 FontDescriptor: FontName: LAACIE+AdvOT9b12cd41+20 Flags: Nonsymbolic FontBBox: -114, -166, 1010, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAACIF+AdvOT9b12cd41+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: LAACIF+AdvOT9b12cd41+fb Flags: Symbolic FontBBox: 0, 0, 854, 697 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: LAACJG+AdvOT2c8ce45a FontSubset: true FirstChar: 40 LastChar: 121 FontDescriptor: FontName: LAACJG+AdvOT2c8ce45a Flags: Nonsymbolic FontBBox: -52, -208, 947, 895 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAACJH+AdvOT1ef757c0 FontSubset: true FirstChar: 37 LastChar: 252 FontDescriptor: FontName: LAACJH+AdvOT1ef757c0 Flags: Serif, Nonsymbolic FontBBox: -20, -250, 947, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LABKOL+AdvPSSym FontSubset: true FirstChar: 129 LastChar: 129 FontDescriptor: FontName: LABKOL+AdvPSSym Flags: Nonsymbolic FontBBox: -177, -291, 1083, 1010 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAACJI+AdvOT7d6df7ab.I FontSubset: true FirstChar: 40 LastChar: 122 FontDescriptor: FontName: LAACJI+AdvOT7d6df7ab.I Flags: Nonsymbolic FontBBox: -135, -250, 1000, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAACJJ+AdvOT1ef757c0+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: LAACJJ+AdvOT1ef757c0+fb Flags: Symbolic FontBBox: 0, -10, 781, 708 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: LAADFF+AdvOTd168d80a.I FontSubset: true FirstChar: 46 LastChar: 118 FontDescriptor: FontName: LAADFF+AdvOTd168d80a.I Flags: Nonsymbolic FontBBox: -145, -208, 968, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LABLEK+AdvOTc8b77491.I FontSubset: true FirstChar: 67 LastChar: 117 FontDescriptor: FontName: LABLEK+AdvOTc8b77491.I Flags: Nonsymbolic FontBBox: -145, -208, 1020, 895 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LABLEL+AdvOT46dcae81 FontSubset: true FirstChar: 73 LastChar: 117 FontDescriptor: FontName: LABLEL+AdvOT46dcae81 Flags: Nonsymbolic FontBBox: -41, -250, 833, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LABPPP+AdvOT7d6df7ab.I+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: LABPPP+AdvOT7d6df7ab.I+fb Flags: Symbolic FontBBox: -156, -250, 802, 708 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: LAADPC+AdvOT1ef757c0+20 FontSubset: true FirstChar: 145 LastChar: 151 FontDescriptor: FontName: LAADPC+AdvOT1ef757c0+20 Flags: Nonsymbolic FontBBox: -135, -187, 1010, 833 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: LAAECC+AdvOT310e2d14+03 FontSubset: true FirstChar: 1 LastChar: 5 FontDescriptor: FontName: LAAECC+AdvOT310e2d14+03 Flags: Symbolic FontBBox: -437, -427, 1541, 1062 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: LAAMHA+AdvOT310e2d14+20 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: LAAMHA+AdvOT310e2d14+20 Flags: Symbolic FontBBox: -1187, -427, 1541, 1062 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: LAAMHB+AdvOT1ef757c0+22 FontSubset: true FirstChar: 21 LastChar: 21 FontDescriptor: FontName: LAAMHB+AdvOT1ef757c0+22 Flags: Nonsymbolic FontBBox: -135, -166, 697, 916 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 222, 688, 458, 709 Annotation: Subtype: Link Rect: 222, 663, 338, 684 Annotation: Subtype: Link Rect: 324, 177, 403, 186 Destination: 35 Annotation: Subtype: Link Rect: 408, 177, 483, 186 Destination: 37 Annotation: Subtype: Link Rect: 488, 177, 543, 186 Destination: 35 Annotation: Subtype: Link Rect: 222, 165, 294, 174 Destination: 34 Annotation: Subtype: Link Rect: 299, 165, 383, 174 Destination: 38 Annotation: Subtype: Link Rect: 388, 165, 451, 174 Destination: 35 Annotation: Subtype: Link Rect: 456, 165, 518, 174 Destination: 35 Annotation: Subtype: Link Rect: 473, 129, 545, 138 Destination: 36 Annotation: Subtype: Link Rect: 222, 117, 240, 126 Destination: 36 Annotation: Subtype: Link Rect: 352, 81, 427, 90 Destination: 34 Annotation: Subtype: Link Rect: 49, 693, 121, 708 Annotation: Subtype: Link Rect: 49, 543, 53, 547 Annotation: Subtype: Link Rect: 56, 541, 111, 548 Annotation: Subtype: Link Rect: 63, 459, 151, 466 Annotation: Subtype: Link Rect: 101, 417, 197, 424 Annotation: Subtype: Link Rect: 49, 408, 100, 415 Annotation: Subtype: Link Rect: 49, 33, 192, 40 Annotation: Subtype: Link Rect: 499, 33, 545, 40 Annotation: Subtype: Link Rect: 49, 787, 314, 801 Annotation: Subtype: Link Rect: 445, 800, 458, 805 Annotation: Subtype: Link Rect: 458, 799, 483, 806 Annotation: Subtype: Link Rect: 458, 781, 545, 788 Thumb: true Page: Label: 2 Annotations: Annotation: Subtype: Link Rect: 97, 739, 200, 748 Destination: 37 Annotation: Subtype: Link Rect: 191, 679, 290, 688 Destination: 34 Annotation: Subtype: Link Rect: 49, 667, 67, 676 Destination: 34 Annotation: Subtype: Link Rect: 73, 667, 143, 676 Destination: 34 Annotation: Subtype: Link Rect: 268, 643, 290, 652 Destination: 37 Annotation: Subtype: Link Rect: 49, 631, 90, 640 Destination: 37 Annotation: Subtype: Link Rect: 59, 536, 89, 545 Destination: 23 Annotation: Subtype: Link Rect: 177, 464, 231, 473 Destination: 35 Annotation: Subtype: Link Rect: 253, 356, 290, 365 Destination: 37 Annotation: Subtype: Link Rect: 49, 344, 111, 353 Destination: 37 Annotation: Subtype: Link Rect: 52, 320, 117, 329 Destination: 37 Annotation: Subtype: Link Rect: 167, 285, 225, 294 Destination: 35 Annotation: Subtype: Link Rect: 81, 177, 156, 186 Destination: 35 Annotation: Subtype: Link Rect: 52, 117, 131, 126 Destination: 37 Annotation: Subtype: Link Rect: 92, 81, 166, 90 Destination: 38 Annotation: Subtype: Link Rect: 174, 81, 227, 90 Destination: 35 Annotation: Subtype: Link Rect: 235, 81, 290, 90 Destination: 36 Annotation: Subtype: Link Rect: 49, 69, 100, 78 Destination: 36 Annotation: Subtype: Link Rect: 350, 631, 464, 640 Destination: 36 Annotation: Subtype: Link Rect: 441, 607, 520, 616 Destination: 37 Annotation: Subtype: Link Rect: 505, 560, 545, 569 Destination: 37 Annotation: Subtype: Link Rect: 304, 548, 321, 557 Destination: 37 Annotation: Subtype: Link Rect: 307, 500, 372, 509 Destination: 37 Annotation: Subtype: Link Rect: 513, 488, 545, 497 Destination: 38 Annotation: Subtype: Link Rect: 304, 476, 321, 485 Destination: 38 Annotation: Subtype: Link Rect: 478, 416, 529, 425 Destination: 36 Annotation: Subtype: Link Rect: 442, 368, 540, 377 Destination: 37 Annotation: Subtype: Link Rect: 536, 332, 545, 341 Destination: 35 Annotation: Subtype: Link Rect: 304, 320, 346, 329 Destination: 35 Annotation: Subtype: Link Rect: 532, 309, 545, 317 Destination: 35 Annotation: Subtype: Link Rect: 304, 297, 350, 306 Destination: 35 Annotation: Subtype: Link Rect: 380, 225, 462, 234 Destination: 35 Annotation: Subtype: Link Rect: 444, 141, 540, 150 Destination: 37 Annotation: Subtype: Link Rect: 400, 105, 467, 114 Destination: 34 Annotation: Subtype: Link Rect: 507, 69, 545, 78 Destination: 37 Annotation: Subtype: Link Rect: 49, 33, 192, 40 Annotation: Subtype: Link Rect: 499, 33, 545, 40 Annotation: Subtype: Link Rect: 456, 799, 545, 806 Thumb: true Page: Label: 3 Annotations: Annotation: Subtype: Link Rect: 49, 237, 66, 246 Destination: 37 Annotation: Subtype: Link Rect: 145, 213, 219, 222 Destination: 37 Annotation: Subtype: Link Rect: 75, 189, 130, 198 Destination: 36 Annotation: Subtype: Link Rect: 186, 177, 251, 186 Destination: 38 Annotation: Subtype: Link Rect: 304, 189, 390, 198 Destination: 38 Annotation: Subtype: Link Rect: 470, 153, 540, 162 Destination: 38 Annotation: Subtype: Link Rect: 481, 129, 540, 138 Destination: 36 Annotation: Subtype: Link Rect: 49, 33, 192, 40 Annotation: Subtype: Link Rect: 499, 33, 545, 40 Annotation: Subtype: Link Rect: 456, 799, 545, 806 Thumb: true Page: Label: 4 Annotations: Annotation: Subtype: Link Rect: 122, 751, 174, 760 Destination: 37 Annotation: Subtype: Link Rect: 161, 715, 239, 724 Destination: 36 Annotation: Subtype: Link Rect: 52, 691, 122, 700 Destination: 36 Annotation: Subtype: Link Rect: 84, 655, 139, 664 Destination: 35 Annotation: Subtype: Link Rect: 153, 631, 234, 640 Destination: 37 Annotation: Subtype: Link Rect: 213, 595, 278, 604 Destination: 36 Annotation: Subtype: Link Rect: 222, 572, 288, 580 Destination: 34 Annotation: Subtype: Link Rect: 49, 560, 111, 569 Destination: 37 Annotation: Subtype: Link Rect: 92, 536, 163, 545 Destination: 35 Annotation: Subtype: Link Rect: 224, 500, 283, 509 Destination: 35 Annotation: Subtype: Link Rect: 169, 344, 228, 353 Destination: 35 Annotation: Subtype: Link Rect: 117, 309, 180, 317 Destination: 36 Annotation: Subtype: Link Rect: 100, 189, 177, 198 Destination: 35 Annotation: Subtype: Link Rect: 283, 93, 290, 102 Destination: 36 Annotation: Subtype: Link Rect: 49, 81, 99, 90 Destination: 36 Annotation: Subtype: Link Rect: 521, 715, 545, 724 Destination: 35 Annotation: Subtype: Link Rect: 304, 703, 344, 712 Destination: 35 Annotation: Subtype: Link Rect: 452, 643, 516, 652 Destination: 38 Annotation: Subtype: Link Rect: 430, 392, 511, 401 Destination: 36 Annotation: Subtype: Link Rect: 443, 309, 515, 317 Destination: 36 Annotation: Subtype: Link Rect: 447, 201, 516, 210 Destination: 34 Annotation: Subtype: Link Rect: 522, 201, 545, 210 Destination: 38 Annotation: Subtype: Link Rect: 304, 189, 344, 198 Destination: 38 Annotation: Subtype: Link Rect: 424, 117, 540, 126 Destination: 38 Annotation: Subtype: Link Rect: 49, 33, 192, 40 Annotation: Subtype: Link Rect: 499, 33, 545, 40 Annotation: Subtype: Link Rect: 456, 799, 545, 806 Thumb: true Page: Label: 5 Annotations: Annotation: Subtype: Link Rect: 150, 715, 229, 724 Destination: 34 Annotation: Subtype: Link Rect: 143, 655, 200, 664 Destination: 37 Annotation: Subtype: Link Rect: 196, 619, 251, 628 Destination: 34 Annotation: Subtype: Link Rect: 129, 416, 184, 425 Destination: 34 Annotation: Subtype: Link Rect: 239, 320, 290, 329 Destination: 34 Annotation: Subtype: Link Rect: 49, 309, 66, 317 Destination: 34 Annotation: Subtype: Link Rect: 246, 285, 290, 294 Destination: 36 Annotation: Subtype: Link Rect: 49, 273, 66, 282 Destination: 36 Annotation: Subtype: Link Rect: 102, 225, 159, 234 Destination: 37 Annotation: Subtype: Link Rect: 279, 201, 290, 210 Destination: 37 Annotation: Subtype: Link Rect: 49, 189, 89, 198 Destination: 37 Annotation: Subtype: Link Rect: 307, 739, 361, 748 Destination: 35 Annotation: Subtype: Link Rect: 358, 679, 394, 688 Destination: 26 Annotation: Subtype: Link Rect: 499, 667, 542, 676 Destination: 26 Annotation: Subtype: Link Rect: 307, 655, 420, 664 Destination: 35 Annotation: Subtype: Link Rect: 511, 560, 545, 569 Destination: 38 Annotation: Subtype: Link Rect: 304, 548, 368, 557 Destination: 38 Annotation: Subtype: Link Rect: 373, 548, 467, 557 Destination: 35 Annotation: Subtype: Link Rect: 361, 476, 421, 485 Destination: 35 Annotation: Subtype: Link Rect: 354, 344, 438, 353 Destination: 37 Annotation: Subtype: Link Rect: 530, 309, 545, 317 Destination: 34 Annotation: Subtype: Link Rect: 304, 297, 341, 306 Destination: 34 Annotation: Subtype: Link Rect: 394, 225, 466, 234 Destination: 36 Annotation: Subtype: Link Rect: 49, 33, 192, 40 Annotation: Subtype: Link Rect: 499, 33, 545, 40 Annotation: Subtype: Link Rect: 456, 799, 545, 806 Thumb: true Page: Label: 6 Annotations: Annotation: Subtype: Link Rect: 255, 560, 290, 569 Destination: 34 Annotation: Subtype: Link Rect: 49, 548, 120, 557 Destination: 34 Annotation: Subtype: Link Rect: 167, 536, 228, 545 Destination: 36 Annotation: Subtype: Link Rect: 86, 249, 167, 258 Destination: 37 Annotation: Subtype: Link Rect: 407, 536, 442, 545 Destination: 27 Annotation: Subtype: Link Rect: 450, 536, 528, 545 Destination: 37 Annotation: Subtype: Link Rect: 351, 440, 406, 449 Destination: 36 Annotation: Subtype: Link Rect: 430, 392, 536, 402 Destination: 37 Annotation: Subtype: Link Rect: 427, 333, 477, 342 Destination: 36 Annotation: Subtype: Link Rect: 419, 273, 507, 282 Destination: 34 Annotation: Subtype: Link Rect: 498, 177, 545, 186 Destination: 35 Annotation: Subtype: Link Rect: 304, 165, 321, 174 Destination: 35 Annotation: Subtype: Link Rect: 49, 33, 192, 40 Annotation: Subtype: Link Rect: 499, 33, 545, 40 Annotation: Subtype: Link Rect: 456, 799, 545, 806 Thumb: true Page: Label: 7 Annotations: Annotation: Subtype: Link Rect: 49, 33, 192, 40 Annotation: Subtype: Link Rect: 499, 33, 545, 40 Annotation: Subtype: Link Rect: 456, 799, 545, 806 Thumb: true Page: Label: 8 Annotations: Annotation: Subtype: Link Rect: 224, 715, 285, 724 Destination: 37 Annotation: Subtype: Link Rect: 113, 512, 193, 521 Destination: 35 Annotation: Subtype: Link Rect: 202, 512, 285, 521 Destination: 35 Annotation: Subtype: Link Rect: 213, 464, 253, 473 Destination: 27 Annotation: Subtype: Link Rect: 267, 464, 290, 473 Destination: 37 Annotation: Subtype: Link Rect: 49, 452, 89, 461 Destination: 37 Annotation: Subtype: Link Rect: 52, 416, 126, 425 Destination: 38 Annotation: Subtype: Link Rect: 146, 404, 210, 413 Destination: 38 Annotation: Subtype: Link Rect: 272, 368, 290, 377 Destination: 38 Annotation: Subtype: Link Rect: 49, 356, 88, 365 Destination: 38 Annotation: Subtype: Link Rect: 252, 332, 287, 341 Destination: 27 Annotation: Subtype: Link Rect: 52, 320, 125, 329 Destination: 35 Annotation: Subtype: Link Rect: 266, 213, 290, 222 Destination: 37 Annotation: Subtype: Link Rect: 49, 201, 89, 210 Destination: 37 Annotation: Subtype: Link Rect: 487, 739, 524, 748 Destination: 27 Annotation: Subtype: Link Rect: 386, 715, 451, 724 Destination: 37 Annotation: Subtype: Link Rect: 500, 691, 545, 700 Destination: 37 Annotation: Subtype: Link Rect: 304, 679, 320, 688 Destination: 37 Annotation: Subtype: Link Rect: 350, 655, 413, 664 Destination: 38 Annotation: Subtype: Link Rect: 449, 643, 482, 652 Destination: 27 Annotation: Subtype: Link Rect: 490, 643, 540, 652 Destination: 34 Annotation: Subtype: Link Rect: 307, 452, 530, 461 Destination: 35 Annotation: Subtype: Link Rect: 336, 368, 404, 377 Destination: 38 Annotation: Subtype: Link Rect: 410, 368, 477, 377 Destination: 38 Annotation: Subtype: Link Rect: 367, 285, 401, 294 Destination: 27 Annotation: Subtype: Link Rect: 409, 285, 470, 294 Destination: 36 Annotation: Subtype: Link Rect: 307, 225, 419, 234 Destination: 37 Annotation: Subtype: Link Rect: 388, 201, 461, 210 Destination: 34 Annotation: Subtype: Link Rect: 49, 33, 192, 40 Annotation: Subtype: Link Rect: 499, 33, 545, 40 Annotation: Subtype: Link Rect: 456, 799, 545, 806 Thumb: true Page: Label: 9 Annotations: Annotation: Subtype: Link Rect: 170, 751, 252, 760 Destination: 36 Annotation: Subtype: Link Rect: 109, 548, 146, 557 Destination: 27 Annotation: Subtype: Link Rect: 157, 548, 237, 557 Destination: 35 Annotation: Subtype: Link Rect: 52, 476, 125, 485 Destination: 37 Annotation: Subtype: Link Rect: 228, 416, 285, 425 Destination: 37 Annotation: Subtype: Link Rect: 111, 368, 187, 377 Destination: 37 Annotation: Subtype: Link Rect: 249, 273, 290, 282 Destination: 37 Annotation: Subtype: Link Rect: 49, 261, 106, 270 Destination: 37 Annotation: Subtype: Link Rect: 111, 261, 172, 270 Destination: 38 Annotation: Subtype: Link Rect: 52, 225, 86, 234 Destination: 27 Annotation: Subtype: Link Rect: 337, 715, 414, 724 Destination: 36 Annotation: Subtype: Link Rect: 418, 715, 530, 724 Destination: 37 Annotation: Subtype: Link Rect: 465, 679, 514, 688 Destination: 35 Annotation: Subtype: Link Rect: 410, 643, 475, 652 Destination: 37 Annotation: Subtype: Link Rect: 464, 595, 501, 604 Destination: 27 Annotation: Subtype: Link Rect: 523, 560, 545, 569 Destination: 34 Annotation: Subtype: Link Rect: 304, 548, 344, 557 Destination: 34 Annotation: Subtype: Link Rect: 519, 512, 545, 521 Destination: 35 Annotation: Subtype: Link Rect: 304, 500, 341, 509 Destination: 35 Annotation: Subtype: Link Rect: 353, 452, 416, 461 Destination: 34 Annotation: Subtype: Link Rect: 386, 416, 450, 425 Destination: 38 Annotation: Subtype: Link Rect: 454, 416, 540, 425 Destination: 37 Annotation: Subtype: Link Rect: 493, 356, 545, 365 Destination: 34 Annotation: Subtype: Link Rect: 304, 344, 321, 353 Destination: 34 Annotation: Subtype: Link Rect: 463, 297, 503, 306 Destination: 27 Annotation: Subtype: Link Rect: 516, 297, 545, 306 Destination: 34 Annotation: Subtype: Link Rect: 304, 285, 344, 294 Destination: 34 Annotation: Subtype: Link Rect: 307, 225, 377, 234 Destination: 38 Annotation: Subtype: Link Rect: 402, 201, 467, 210 Destination: 38 Annotation: Subtype: Link Rect: 49, 33, 192, 40 Annotation: Subtype: Link Rect: 499, 33, 545, 40 Annotation: Subtype: Link Rect: 456, 799, 545, 806 Thumb: true Page: Label: 10 Annotations: Annotation: Subtype: Link Rect: 282, 683, 333, 690 Destination: 35 Annotation: Subtype: Link Rect: 142, 674, 156, 681 Destination: 35 Annotation: Subtype: Link Rect: 160, 674, 210, 681 Destination: 35 Annotation: Subtype: Link Rect: 398, 683, 454, 690 Destination: 37 Annotation: Subtype: Link Rect: 384, 657, 453, 664 Destination: 34 Annotation: Subtype: Link Rect: 498, 640, 539, 647 Destination: 36 Annotation: Subtype: Link Rect: 241, 624, 283, 631 Destination: 38 Annotation: Subtype: Link Rect: 286, 624, 330, 631 Destination: 35 Annotation: Subtype: Link Rect: 487, 615, 534, 622 Destination: 35 Annotation: Subtype: Link Rect: 180, 580, 252, 587 Destination: 36 Annotation: Subtype: Link Rect: 366, 580, 437, 587 Destination: 36 Annotation: Subtype: Link Rect: 228, 545, 274, 552 Destination: 35 Annotation: Subtype: Link Rect: 392, 545, 438, 552 Destination: 35 Annotation: Subtype: Link Rect: 236, 529, 283, 536 Destination: 34 Annotation: Subtype: Link Rect: 201, 503, 254, 510 Destination: 35 Annotation: Subtype: Link Rect: 301, 477, 330, 484 Destination: 37 Annotation: Subtype: Link Rect: 142, 468, 173, 475 Destination: 37 Annotation: Subtype: Link Rect: 513, 477, 541, 484 Destination: 37 Annotation: Subtype: Link Rect: 349, 468, 380, 475 Destination: 37 Annotation: Subtype: Link Rect: 285, 452, 331, 459 Destination: 35 Annotation: Subtype: Link Rect: 142, 443, 191, 450 Destination: 35 Annotation: Subtype: Link Rect: 195, 443, 249, 450 Destination: 36 Annotation: Subtype: Link Rect: 352, 443, 406, 450 Destination: 36 Annotation: Subtype: Link Rect: 289, 417, 328, 424 Destination: 35 Annotation: Subtype: Link Rect: 142, 408, 156, 415 Destination: 35 Annotation: Subtype: Link Rect: 160, 408, 203, 415 Destination: 38 Annotation: Subtype: Link Rect: 315, 391, 333, 398 Destination: 36 Annotation: Subtype: Link Rect: 142, 382, 173, 389 Destination: 36 Annotation: Subtype: Link Rect: 177, 382, 220, 389 Destination: 36 Annotation: Subtype: Link Rect: 297, 366, 333, 373 Destination: 36 Annotation: Subtype: Link Rect: 142, 357, 156, 364 Destination: 36 Annotation: Subtype: Link Rect: 233, 357, 283, 364 Destination: 36 Annotation: Subtype: Link Rect: 255, 348, 311, 355 Destination: 34 Annotation: Subtype: Link Rect: 145, 322, 193, 329 Destination: 34 Annotation: Subtype: Link Rect: 383, 322, 430, 329 Destination: 35 Annotation: Subtype: Link Rect: 433, 322, 492, 329 Destination: 37 Annotation: Subtype: Link Rect: 292, 305, 331, 312 Destination: 35 Annotation: Subtype: Link Rect: 142, 297, 194, 303 Destination: 38 Annotation: Subtype: Link Rect: 211, 271, 270, 278 Destination: 35 Annotation: Subtype: Link Rect: 282, 229, 330, 236 Destination: 38 Annotation: Subtype: Link Rect: 307, 212, 333, 219 Destination: 35 Annotation: Subtype: Link Rect: 142, 203, 173, 210 Destination: 35 Annotation: Subtype: Link Rect: 301, 186, 333, 193 Destination: 36 Annotation: Subtype: Link Rect: 142, 177, 156, 184 Destination: 36 Annotation: Subtype: Link Rect: 49, 33, 192, 40 Annotation: Subtype: Link Rect: 499, 33, 545, 40 Annotation: Subtype: Link Rect: 456, 799, 545, 806 Thumb: true Page: Label: 11 Annotations: Annotation: Subtype: Link Rect: 135, 254, 244, 263 Destination: 36 Annotation: Subtype: Link Rect: 482, 266, 545, 275 Destination: 37 Annotation: Subtype: Link Rect: 304, 254, 320, 263 Destination: 37 Annotation: Subtype: Link Rect: 476, 230, 513, 239 Destination: 27 Annotation: Subtype: Link Rect: 489, 218, 545, 227 Destination: 36 Annotation: Subtype: Link Rect: 304, 206, 320, 215 Destination: 36 Annotation: Subtype: Link Rect: 433, 206, 507, 215 Destination: 36 Annotation: Subtype: Link Rect: 511, 206, 545, 215 Destination: 36 Annotation: Subtype: Link Rect: 304, 194, 347, 203 Destination: 36 Annotation: Subtype: Link Rect: 519, 170, 545, 179 Destination: 37 Annotation: Subtype: Link Rect: 304, 158, 320, 167 Destination: 37 Annotation: Subtype: Link Rect: 374, 666, 424, 673 Destination: 38 Annotation: Subtype: Link Rect: 296, 632, 328, 639 Destination: 34 Annotation: Subtype: Link Rect: 142, 623, 156, 630 Destination: 34 Annotation: Subtype: Link Rect: 421, 623, 470, 630 Destination: 34 Annotation: Subtype: Link Rect: 181, 588, 233, 595 Destination: 38 Annotation: Subtype: Link Rect: 352, 580, 395, 586 Destination: 36 Annotation: Subtype: Link Rect: 288, 572, 330, 579 Destination: 35 Annotation: Subtype: Link Rect: 142, 563, 156, 570 Destination: 35 Annotation: Subtype: Link Rect: 160, 563, 203, 570 Destination: 35 Annotation: Subtype: Link Rect: 374, 537, 415, 544 Destination: 38 Annotation: Subtype: Link Rect: 283, 512, 330, 519 Destination: 37 Annotation: Subtype: Link Rect: 142, 503, 195, 510 Destination: 38 Annotation: Subtype: Link Rect: 199, 503, 256, 510 Destination: 37 Annotation: Subtype: Link Rect: 432, 503, 482, 510 Destination: 38 Annotation: Subtype: Link Rect: 185, 477, 232, 484 Destination: 37 Annotation: Subtype: Link Rect: 145, 452, 185, 459 Destination: 38 Annotation: Subtype: Link Rect: 168, 426, 208, 433 Destination: 35 Annotation: Subtype: Link Rect: 266, 409, 314, 416 Destination: 37 Annotation: Subtype: Link Rect: 191, 400, 247, 407 Destination: 34 Annotation: Subtype: Link Rect: 248, 377, 294, 383 Destination: 38 Annotation: Subtype: Link Rect: 512, 368, 541, 375 Destination: 37 Annotation: Subtype: Link Rect: 349, 359, 363, 366 Destination: 37 Annotation: Subtype: Link Rect: 224, 333, 278, 340 Destination: 37 Annotation: Subtype: Link Rect: 352, 333, 412, 340 Destination: 38 Annotation: Subtype: Link Rect: 218, 307, 283, 314 Destination: 35 Annotation: Subtype: Link Rect: 49, 33, 192, 40 Annotation: Subtype: Link Rect: 499, 33, 545, 40 Annotation: Subtype: Link Rect: 456, 799, 545, 806 Thumb: true Page: Label: 12 Annotations: Annotation: Subtype: Link Rect: 118, 373, 180, 382 Destination: 36 Annotation: Subtype: Link Rect: 199, 314, 247, 323 Destination: 36 Annotation: Subtype: Link Rect: 52, 218, 84, 227 Destination: 27 Annotation: Subtype: Link Rect: 94, 218, 148, 227 Destination: 35 Annotation: Subtype: Link Rect: 204, 158, 256, 167 Destination: 34 Annotation: Subtype: Link Rect: 458, 469, 540, 478 Destination: 37 Annotation: Subtype: Link Rect: 395, 457, 476, 466 Destination: 37 Annotation: Subtype: Link Rect: 361, 433, 388, 442 Destination: 30 Annotation: Subtype: Link Rect: 458, 290, 489, 299 Destination: 32 Annotation: Subtype: Link Rect: 442, 266, 515, 275 Destination: 38 Annotation: Subtype: Link Rect: 519, 266, 545, 275 Destination: 36 Annotation: Subtype: Link Rect: 304, 254, 395, 263 Destination: 36 Annotation: Subtype: Link Rect: 401, 254, 504, 263 Destination: 38 Annotation: Subtype: Link Rect: 510, 254, 545, 263 Destination: 36 Annotation: Subtype: Link Rect: 304, 242, 369, 251 Destination: 36 Annotation: Subtype: Link Rect: 416, 242, 472, 251 Destination: 37 Annotation: Subtype: Link Rect: 476, 242, 545, 251 Destination: 36 Annotation: Subtype: Link Rect: 304, 230, 321, 239 Destination: 36 Annotation: Subtype: Link Rect: 326, 230, 411, 239 Destination: 38 Annotation: Subtype: Link Rect: 512, 86, 545, 95 Destination: 36 Annotation: Subtype: Link Rect: 304, 74, 345, 83 Destination: 36 Annotation: Subtype: Link Rect: 49, 33, 192, 40 Annotation: Subtype: Link Rect: 499, 33, 545, 40 Annotation: Subtype: Link Rect: 456, 799, 545, 806 Thumb: true Page: Label: 13 Annotations: Annotation: Subtype: Link Rect: 52, 739, 129, 748 Destination: 36 Annotation: Subtype: Link Rect: 226, 715, 285, 724 Destination: 35 Annotation: Subtype: Link Rect: 202, 655, 269, 664 Destination: 36 Annotation: Subtype: Link Rect: 49, 619, 124, 628 Destination: 38 Annotation: Subtype: Link Rect: 88, 548, 168, 557 Destination: 35 Annotation: Subtype: Link Rect: 90, 165, 174, 174 Destination: 36 Annotation: Subtype: Link Rect: 201, 117, 251, 126 Destination: 36 Annotation: Subtype: Link Rect: 52, 69, 134, 78 Destination: 36 Annotation: Subtype: Link Rect: 49, 33, 192, 40 Annotation: Subtype: Link Rect: 499, 33, 545, 40 Annotation: Subtype: Link Rect: 456, 799, 545, 806 Thumb: true Page: Label: 14 Annotations: Annotation: Subtype: Link Rect: 250, 619, 290, 628 Annotation: Subtype: Link Rect: 49, 607, 65, 616 Annotation: Subtype: Link Rect: 264, 595, 290, 604 Annotation: Subtype: Link Rect: 49, 583, 101, 592 Annotation: Subtype: Link Rect: 239, 583, 277, 592 Destination: 27 Annotation: Subtype: Link Rect: 72, 572, 136, 580 Annotation: Subtype: Link Rect: 160, 560, 190, 569 Destination: 23 Annotation: Subtype: Link Rect: 76, 524, 150, 533 Annotation: Subtype: Link Rect: 430, 751, 523, 760 Annotation: Subtype: Link Rect: 307, 739, 363, 748 Annotation: Subtype: Link Rect: 60, 452, 147, 459 Annotation: Subtype: Link Rect: 266, 425, 290, 432 Annotation: Subtype: Link Rect: 49, 417, 75, 424 Annotation: Subtype: Link Rect: 186, 389, 237, 396 Annotation: Subtype: Link Rect: 61, 353, 114, 360 Annotation: Subtype: Link Rect: 138, 325, 210, 332 Annotation: Subtype: Link Rect: 251, 305, 290, 312 Annotation: Subtype: Link Rect: 49, 297, 87, 304 Annotation: Subtype: Link Rect: 255, 269, 290, 276 Annotation: Subtype: Link Rect: 49, 261, 73, 268 Annotation: Subtype: Link Rect: 282, 241, 290, 248 Annotation: Subtype: Link Rect: 49, 233, 100, 240 Annotation: Subtype: Link Rect: 115, 205, 198, 212 Annotation: Subtype: Link Rect: 110, 170, 190, 176 Annotation: Subtype: Link Rect: 282, 142, 290, 149 Annotation: Subtype: Link Rect: 49, 134, 142, 141 Annotation: Subtype: Link Rect: 266, 106, 290, 113 Annotation: Subtype: Link Rect: 49, 98, 106, 105 Annotation: Subtype: Link Rect: 349, 452, 417, 459 Annotation: Subtype: Link Rect: 376, 417, 451, 424 Annotation: Subtype: Link Rect: 469, 389, 545, 396 Annotation: Subtype: Link Rect: 438, 369, 509, 376 Annotation: Subtype: Link Rect: 451, 349, 500, 356 Annotation: Subtype: Link Rect: 413, 321, 494, 328 Annotation: Subtype: Link Rect: 367, 293, 434, 300 Annotation: Subtype: Link Rect: 349, 257, 426, 264 Annotation: Subtype: Link Rect: 426, 229, 499, 236 Annotation: Subtype: Link Rect: 475, 174, 533, 181 Annotation: Subtype: Link Rect: 441, 146, 526, 153 Annotation: Subtype: Link Rect: 488, 126, 545, 133 Annotation: Subtype: Link Rect: 396, 98, 471, 105 Annotation: Subtype: Link Rect: 49, 33, 192, 40 Annotation: Subtype: Link Rect: 499, 33, 545, 40 Annotation: Subtype: Link Rect: 456, 799, 545, 806 Thumb: true Page: Label: 15 Annotations: Annotation: Subtype: Link Rect: 158, 737, 227, 744 Annotation: Subtype: Link Rect: 166, 710, 217, 716 Annotation: Subtype: Link Rect: 155, 682, 239, 689 Annotation: Subtype: Link Rect: 150, 654, 212, 661 Annotation: Subtype: Link Rect: 117, 618, 211, 625 Annotation: Subtype: Link Rect: 194, 590, 269, 597 Annotation: Subtype: Link Rect: 222, 570, 290, 577 Annotation: Subtype: Link Rect: 134, 542, 206, 549 Annotation: Subtype: Link Rect: 236, 514, 290, 521 Annotation: Subtype: Link Rect: 191, 486, 256, 493 Annotation: Subtype: Link Rect: 147, 458, 228, 465 Annotation: Subtype: Link Rect: 141, 439, 216, 446 Annotation: Subtype: Link Rect: 60, 411, 110, 418 Annotation: Subtype: Link Rect: 60, 383, 149, 390 Annotation: Subtype: Link Rect: 263, 355, 290, 362 Annotation: Subtype: Link Rect: 49, 347, 116, 354 Annotation: Subtype: Link Rect: 154, 319, 238, 326 Annotation: Subtype: Link Rect: 87, 291, 164, 298 Annotation: Subtype: Link Rect: 266, 271, 290, 278 Annotation: Subtype: Link Rect: 49, 263, 106, 270 Annotation: Subtype: Link Rect: 112, 227, 183, 234 Annotation: Subtype: Link Rect: 90, 199, 171, 206 Annotation: Subtype: Link Rect: 266, 172, 290, 179 Annotation: Subtype: Link Rect: 49, 164, 116, 171 Annotation: Subtype: Link Rect: 151, 136, 235, 143 Annotation: Subtype: Link Rect: 138, 108, 185, 115 Annotation: Subtype: Link Rect: 197, 80, 281, 87 Annotation: Subtype: Link Rect: 315, 725, 404, 732 Annotation: Subtype: Link Rect: 315, 690, 402, 697 Annotation: Subtype: Link Rect: 362, 654, 431, 661 Annotation: Subtype: Link Rect: 342, 626, 394, 633 Annotation: Subtype: Link Rect: 342, 598, 408, 605 Annotation: Subtype: Link Rect: 349, 554, 402, 561 Annotation: Subtype: Link Rect: 405, 526, 476, 533 Annotation: Subtype: Link Rect: 342, 490, 422, 497 Annotation: Subtype: Link Rect: 423, 462, 495, 469 Annotation: Subtype: Link Rect: 517, 435, 545, 442 Annotation: Subtype: Link Rect: 304, 427, 359, 434 Annotation: Subtype: Link Rect: 315, 399, 380, 406 Annotation: Subtype: Link Rect: 430, 343, 527, 350 Annotation: Subtype: Link Rect: 405, 307, 463, 314 Annotation: Subtype: Link Rect: 494, 287, 545, 294 Annotation: Subtype: Link Rect: 304, 279, 328, 286 Annotation: Subtype: Link Rect: 407, 243, 471, 250 Annotation: Subtype: Link Rect: 404, 207, 472, 214 Annotation: Subtype: Link Rect: 521, 180, 545, 186 Annotation: Subtype: Link Rect: 304, 172, 361, 179 Annotation: Subtype: Link Rect: 537, 152, 545, 159 Annotation: Subtype: Link Rect: 304, 144, 386, 151 Annotation: Subtype: Link Rect: 471, 116, 541, 123 Annotation: Subtype: Link Rect: 492, 88, 545, 95 Annotation: Subtype: Link Rect: 304, 80, 321, 87 Annotation: Subtype: Link Rect: 49, 33, 192, 40 Annotation: Subtype: Link Rect: 499, 33, 545, 40 Annotation: Subtype: Link Rect: 456, 799, 545, 806 Thumb: true Page: Label: 16 Annotations: Annotation: Subtype: Link Rect: 119, 729, 186, 736 Annotation: Subtype: Link Rect: 208, 702, 267, 709 Annotation: Subtype: Link Rect: 100, 666, 170, 673 Annotation: Subtype: Link Rect: 209, 638, 279, 645 Annotation: Subtype: Link Rect: 60, 610, 118, 617 Annotation: Subtype: Link Rect: 192, 590, 265, 597 Annotation: Subtype: Link Rect: 137, 562, 212, 569 Annotation: Subtype: Link Rect: 249, 534, 290, 541 Annotation: Subtype: Link Rect: 49, 526, 82, 533 Annotation: Subtype: Link Rect: 266, 498, 290, 505 Annotation: Subtype: Link Rect: 49, 490, 126, 497 Annotation: Subtype: Link Rect: 198, 454, 290, 461 Annotation: Subtype: Link Rect: 87, 411, 166, 418 Annotation: Subtype: Link Rect: 94, 375, 184, 382 Annotation: Subtype: Link Rect: 133, 339, 223, 346 Annotation: Subtype: Link Rect: 94, 311, 193, 318 Annotation: Subtype: Link Rect: 197, 283, 274, 290 Annotation: Subtype: Link Rect: 187, 235, 260, 242 Annotation: Subtype: Link Rect: 60, 199, 119, 206 Annotation: Subtype: Link Rect: 60, 148, 150, 155 Annotation: Subtype: Link Rect: 108, 112, 178, 119 Annotation: Subtype: Link Rect: 94, 76, 168, 83 Annotation: Subtype: Link Rect: 486, 737, 545, 744 Annotation: Subtype: Link Rect: 304, 729, 325, 736 Annotation: Subtype: Link Rect: 339, 702, 398, 709 Annotation: Subtype: Link Rect: 392, 666, 462, 673 Annotation: Subtype: Link Rect: 467, 630, 542, 637 Annotation: Subtype: Link Rect: 404, 602, 504, 609 Annotation: Subtype: Link Rect: 367, 566, 444, 573 Annotation: Subtype: Link Rect: 380, 538, 459, 545 Annotation: Subtype: Link Rect: 339, 502, 412, 509 Annotation: Subtype: Link Rect: 349, 474, 417, 481 Annotation: Subtype: Link Rect: 453, 454, 518, 461 Annotation: Subtype: Link Rect: 521, 435, 545, 442 Annotation: Subtype: Link Rect: 304, 427, 361, 434 Annotation: Subtype: Link Rect: 456, 399, 521, 406 Annotation: Subtype: Link Rect: 486, 379, 535, 386 Annotation: Subtype: Link Rect: 441, 351, 515, 358 Annotation: Subtype: Link Rect: 506, 323, 545, 330 Annotation: Subtype: Link Rect: 304, 315, 334, 322 Annotation: Subtype: Link Rect: 537, 295, 545, 302 Annotation: Subtype: Link Rect: 304, 287, 359, 294 Annotation: Subtype: Link Rect: 521, 267, 545, 274 Annotation: Subtype: Link Rect: 304, 259, 371, 266 Annotation: Subtype: Link Rect: 425, 239, 485, 246 Annotation: Subtype: Link Rect: 430, 191, 485, 198 Annotation: Subtype: Link Rect: 420, 156, 499, 163 Annotation: Subtype: Link Rect: 342, 128, 412, 135 Annotation: Subtype: Link Rect: 315, 100, 367, 107 Annotation: Subtype: Link Rect: 349, 72, 404, 79 Annotation: Subtype: Link Rect: 49, 33, 192, 40 Annotation: Subtype: Link Rect: 499, 33, 545, 40 Annotation: Subtype: Link Rect: 456, 799, 545, 806 Thumb: true Page: Label: 17 Annotations: Annotation: Subtype: Link Rect: 160, 745, 236, 752 Annotation: Subtype: Link Rect: 194, 718, 268, 724 Annotation: Subtype: Link Rect: 282, 690, 290, 697 Annotation: Subtype: Link Rect: 49, 682, 121, 689 Annotation: Subtype: Link Rect: 180, 654, 249, 661 Annotation: Subtype: Link Rect: 166, 626, 225, 633 Annotation: Subtype: Link Rect: 223, 598, 285, 605 Annotation: Subtype: Link Rect: 118, 570, 177, 577 Annotation: Subtype: Link Rect: 126, 550, 216, 557 Annotation: Subtype: Link Rect: 189, 522, 279, 529 Annotation: Subtype: Link Rect: 180, 494, 260, 501 Annotation: Subtype: Link Rect: 97, 466, 172, 473 Annotation: Subtype: Link Rect: 282, 447, 290, 453 Annotation: Subtype: Link Rect: 49, 439, 119, 446 Annotation: Subtype: Link Rect: 146, 411, 196, 418 Annotation: Subtype: Link Rect: 219, 391, 286, 398 Annotation: Subtype: Link Rect: 184, 371, 259, 378 Annotation: Subtype: Link Rect: 235, 351, 290, 358 Annotation: Subtype: Link Rect: 49, 343, 74, 350 Annotation: Subtype: Link Rect: 145, 315, 209, 322 Annotation: Subtype: Link Rect: 141, 287, 259, 294 Annotation: Subtype: Link Rect: 214, 259, 270, 266 Annotation: Subtype: Link Rect: 60, 231, 167, 238 Annotation: Subtype: Link Rect: 129, 203, 204, 210 Annotation: Subtype: Link Rect: 94, 168, 162, 175 Annotation: Subtype: Link Rect: 97, 140, 181, 147 Annotation: Subtype: Link Rect: 119, 112, 220, 119 Annotation: Subtype: Link Rect: 121, 76, 202, 83 Annotation: Subtype: Link Rect: 474, 729, 545, 736 Annotation: Subtype: Link Rect: 386, 702, 441, 709 Annotation: Subtype: Link Rect: 349, 666, 425, 673 Annotation: Subtype: Link Rect: 388, 646, 453, 653 Annotation: Subtype: Link Rect: 445, 626, 504, 633 Annotation: Subtype: Link Rect: 431, 598, 502, 605 Annotation: Subtype: Link Rect: 353, 570, 438, 577 Annotation: Subtype: Link Rect: 349, 542, 430, 549 Annotation: Subtype: Link Rect: 387, 514, 469, 521 Annotation: Subtype: Link Rect: 506, 494, 545, 501 Annotation: Subtype: Link Rect: 304, 486, 321, 493 Annotation: Subtype: Link Rect: 521, 458, 545, 465 Annotation: Subtype: Link Rect: 304, 450, 379, 457 Annotation: Subtype: Link Rect: 445, 423, 513, 430 Annotation: Subtype: Link Rect: 435, 395, 515, 402 Annotation: Subtype: Link Rect: 364, 367, 415, 374 Annotation: Subtype: Link Rect: 521, 347, 545, 354 Annotation: Subtype: Link Rect: 304, 339, 359, 346 Annotation: Subtype: Link Rect: 349, 311, 417, 318 Annotation: Subtype: Link Rect: 469, 291, 545, 298 Annotation: Subtype: Link Rect: 304, 283, 318, 290 Annotation: Subtype: Link Rect: 521, 263, 545, 270 Annotation: Subtype: Link Rect: 304, 255, 333, 262 Annotation: Subtype: Link Rect: 383, 227, 445, 234 Annotation: Subtype: Link Rect: 450, 199, 501, 206 Annotation: Subtype: Link Rect: 537, 172, 545, 179 Annotation: Subtype: Link Rect: 304, 164, 373, 171 Annotation: Subtype: Link Rect: 485, 144, 538, 151 Annotation: Subtype: Link Rect: 392, 116, 439, 123 Annotation: Subtype: Link Rect: 521, 88, 545, 95 Annotation: Subtype: Link Rect: 304, 80, 339, 87 Annotation: Subtype: Link Rect: 49, 33, 192, 40 Annotation: Subtype: Link Rect: 499, 33, 545, 40 Annotation: Subtype: Link Rect: 456, 799, 545, 806 Thumb: true Page: Label: 18 Annotations: Annotation: Subtype: Link Rect: 282, 745, 290, 752 Annotation: Subtype: Link Rect: 49, 737, 119, 744 Annotation: Subtype: Link Rect: 281, 718, 290, 724 Annotation: Subtype: Link Rect: 49, 710, 90, 716 Annotation: Subtype: Link Rect: 168, 682, 245, 689 Annotation: Subtype: Link Rect: 230, 654, 290, 661 Annotation: Subtype: Link Rect: 49, 646, 74, 653 Annotation: Subtype: Link Rect: 185, 618, 241, 625 Annotation: Subtype: Link Rect: 166, 590, 220, 597 Annotation: Subtype: Link Rect: 180, 562, 259, 569 Annotation: Subtype: Link Rect: 159, 534, 240, 541 Annotation: Subtype: Link Rect: 131, 506, 182, 513 Annotation: Subtype: Link Rect: 188, 478, 262, 485 Annotation: Subtype: Link Rect: 210, 450, 264, 457 Annotation: Subtype: Link Rect: 181, 423, 237, 430 Annotation: Subtype: Link Rect: 282, 395, 290, 402 Annotation: Subtype: Link Rect: 49, 387, 117, 394 Annotation: Subtype: Link Rect: 114, 351, 189, 358 Annotation: Subtype: Link Rect: 152, 331, 228, 338 Annotation: Subtype: Link Rect: 132, 303, 195, 310 Annotation: Subtype: Link Rect: 235, 283, 290, 290 Annotation: Subtype: Link Rect: 49, 275, 67, 282 Annotation: Subtype: Link Rect: 167, 255, 245, 262 Annotation: Subtype: Link Rect: 431, 745, 494, 752 Annotation: Subtype: Link Rect: 451, 718, 506, 724 Annotation: Subtype: Link Rect: 375, 690, 460, 697 Annotation: Subtype: Link Rect: 410, 662, 492, 669 Annotation: Subtype: Link Rect: 422, 634, 499, 641 Annotation: Subtype: Link Rect: 315, 606, 378, 613 Annotation: Subtype: Link Rect: 425, 578, 476, 585 Annotation: Subtype: Link Rect: 500, 550, 545, 557 Annotation: Subtype: Link Rect: 304, 542, 339, 549 Annotation: Subtype: Link Rect: 537, 502, 545, 509 Annotation: Subtype: Link Rect: 304, 494, 345, 501 Annotation: Subtype: Link Rect: 461, 466, 545, 473 Annotation: Subtype: Link Rect: 304, 458, 331, 465 Annotation: Subtype: Link Rect: 388, 431, 453, 438 Annotation: Subtype: Link Rect: 470, 403, 533, 410 Annotation: Subtype: Link Rect: 427, 375, 519, 382 Annotation: Subtype: Link Rect: 395, 347, 476, 354 Annotation: Subtype: Link Rect: 440, 319, 499, 326 Annotation: Subtype: Link Rect: 496, 291, 545, 298 Annotation: Subtype: Link Rect: 304, 283, 346, 290 Annotation: Subtype: Link Rect: 396, 255, 475, 262 Annotation: Subtype: Link Rect: 49, 33, 192, 40 Annotation: Subtype: Link Rect: 499, 33, 545, 40 Annotation: Subtype: Link Rect: 456, 799, 545, 806 Thumb: true Checksum: 748f5ccb Type: CRC32 Checksum: 109910392559d7d5f1cfb9e04ab59433 Type: MD5 Checksum: b07c24b01bee8021b52067524b70da3f591f427c Type: SHA-1 Checksum: c27791b64ae7d0b5aca9b946c2b063eba98d30a3c7da002eafa7766954c9dc55 Type: SHA-256