5312269b4a51d9110d374c8bf37c84a3 pmc_11099799.pdf 3de9cafe49c3748df939c295ab0dc5c64a5bcf6c pmc_11099799.pdf 20f700f2998c31ecea6482f9583a03f2ce0254a33911a0f8ddedaac1eb9413f4 pmc_11099799.pdf Title: Peripheral and intestinal T lymphocyte subsets in dogs with chronic inflammatory enteropathy Creator: Arbortext Advanced Print Publisher 9.1.520/W Unicode Producer: Acrobat Distiller 11.0 (Windows) CreationDate: Thu May 9 05:27:13 2024 CEST ModDate: Thu May 9 05:27:13 2024 CEST Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 12 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 2857581 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- EEBHAE+AdvTT6071803a.B Type 1C WinAnsi yes yes no 469 0 EEBHED+AdvOT582d4acf Type 1C WinAnsi yes yes no 470 0 EEBHEE+AdvP4C4E59 Type 1C Custom yes yes yes 471 0 EEBHHE+AdvTTa9c1b374 Type 1C WinAnsi yes yes no 472 0 EEBHHF+AdvTTa9c1b374+03 Type 1C Custom yes yes yes 473 0 EEBHHG+AdvTTeb5f0e55.I Type 1C WinAnsi yes yes no 474 0 EEBIIB+AdvTTa9c1b374+20 Type 1C Custom yes yes yes 475 0 EEBKME+AdvP4C4E74 Type 1C Custom yes yes no 218 0 EEBLKB+AdvTTfac587ca.B Type 1C WinAnsi yes yes no 219 0 EEBLJA+AdvTTc0096231+22 Type 1C Custom yes yes yes 63 0 EEEFPO+AdvTT9c438aa4.BI Type 1C WinAnsi yes yes no 220 0 EEEFPP+AdvP4C4E46 Type 1C WinAnsi yes yes no 103 0 EEEGAP+AdvTT6071803a.B+03 Type 1C Custom yes yes yes 104 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-04-05 02:48:12 CEST RepresentationInformation: pmc_11099799.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-04-04 02:07:15 CEST Size: 2857581 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 496 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Peripheral and intestinal T lymphocyte subsets in dogs with chronic inflammatory enteropathy Destination: atl_JVIM_17036_ Children: Item: Title: 1 INTRODUCTION Destination: HeadingJVIM_17036jvim17036-sec-0007 Item: Title: 2 MATERIALS AND METHODS Destination: HeadingJVIM_17036jvim17036-sec-0008 Children: Item: Title: 2.1 Study groups Destination: HeadingJVIM_17036jvim17036-sec-0009 Children: Item: Title: 2.1.1 Healthy control dogs Destination: HeadingJVIM_17036jvim17036-sec-0010 Item: Title: 2.1.2 CIE dogs Destination: HeadingJVIM_17036jvim17036-sec-0011 Item: Title: 2.2 Sample collection and endoscopic and histopathologic scoring Destination: HeadingJVIM_17036jvim17036-sec-0012 Item: Title: 2.3 PBL, IEL, and LPL isolation Destination: HeadingJVIM_17036jvim17036-sec-0013 Item: Title: 2.4 Flow cytometry Destination: HeadingJVIM_17036jvim17036-sec-0014 Item: Title: 2.5 Statistical analysis Destination: HeadingJVIM_17036jvim17036-sec-0015 Item: Title: 3 RESULTS Destination: HeadingJVIM_17036jvim17036-sec-0016 Children: Item: Title: 3.1 Animals Destination: HeadingJVIM_17036jvim17036-sec-0017 Item: Title: 3.2 Clinical, endoscopic, and histopathological evaluation Destination: HeadingJVIM_17036jvim17036-sec-0018 Item: Title: 3.3 Peripheral blood immunophenotype Destination: HeadingJVIM_17036jvim17036-sec-0019 Item: Title: 3.4 Intestinal immunophenotype Destination: HeadingJVIM_17036jvim17036-sec-0020 Item: Title: 3.5 Associations between PBL subsets and CBC-derived inflammatory biomarkers and clinical, endoscopic, and histopathologic... Destination: HeadingJVIM_17036jvim17036-sec-0021 Item: Title: 4 DISCUSSION Destination: HeadingJVIM_17036jvim17036-sec-0022 Item: Title: ACKNOWLEDGMENT Destination: HeadingJVIM_17036jvim17036-sec-0023 Item: Title: CONFLICT OF INTEREST DECLARATION Destination: HeadingJVIM_17036jvim17036-sec-0024 Item: Title: OFF-LABEL ANTIMICROBIAL DECLARATION Destination: HeadingJVIM_17036jvim17036-sec-0025 Item: Title: INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC) OR OTHER APPROVAL DECLARATION Destination: HeadingJVIM_17036jvim17036-sec-0026 Item: Title: HUMAN ETHICS APPROVAL DECLARATION Destination: HeadingJVIM_17036jvim17036-sec-0027 Item: Title: REFERENCES Destination: HeadingJVIM_17036jvim17036-bibl-00011 Info: Title: Peripheral and intestinal T lymphocyte subsets in dogs with chronic inflammatory enteropathy Creator: Arbortext Advanced Print Publisher 9.1.520/W Unicode Producer: Acrobat Distiller 11.0 (Windows) CreationDate: Thu May 09 05:57:13 CEST 2024 ModDate: Thu May 09 05:57:13 CEST 2024 ID: 0xa1c0b9f974fb3e7156759e906c4e2f8a, 0xaefb8a8b2be8fcf3085e4bde73e43da5 Filters: FilterPipeline: FlateDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 2093 ImageHeight: 2082 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode ColorSpace: ICCBased Intent: Perceptual Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1538 ImageHeight: 1941 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode ColorSpace: ICCBased Intent: Perceptual Fonts: Type1: Font: BaseFont: EEEFPP+AdvP4C4E46 FontSubset: true FirstChar: 80 LastChar: 80 FontDescriptor: FontName: EEEFPP+AdvP4C4E46 Flags: Nonsymbolic FontBBox: 55, -1000, 999, 0 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EEEGAP+AdvTT6071803a.B+03 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: EEEGAP+AdvTT6071803a.B+03 Flags: Symbolic FontBBox: -510, -270, 1072, 979 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EEBHAE+AdvTT6071803a.B FontSubset: true FirstChar: 37 LastChar: 241 FontDescriptor: FontName: EEBHAE+AdvTT6071803a.B Flags: Nonsymbolic FontBBox: -52, -177, 1041, 947 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EEBHED+AdvOT582d4acf FontSubset: true FirstChar: 180 LastChar: 180 FontDescriptor: FontName: EEBHED+AdvOT582d4acf Flags: Nonsymbolic FontBBox: -72, -208, 927, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EEBHEE+AdvP4C4E59 FontSubset: true FirstChar: 1 LastChar: 61 FontDescriptor: FontName: EEBHEE+AdvP4C4E59 Flags: Symbolic FontBBox: -31, -250, 1000, 750 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EEBHHE+AdvTTa9c1b374 FontSubset: true FirstChar: 37 LastChar: 252 FontDescriptor: FontName: EEBHHE+AdvTTa9c1b374 Flags: Nonsymbolic FontBBox: -41, -177, 1010, 927 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EEBHHF+AdvTTa9c1b374+03 FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: EEBHHF+AdvTTa9c1b374+03 Flags: Symbolic FontBBox: -500, -260, 1041, 947 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EEBHHG+AdvTTeb5f0e55.I FontSubset: true FirstChar: 38 LastChar: 241 FontDescriptor: FontName: EEBHHG+AdvTTeb5f0e55.I Flags: Nonsymbolic FontBBox: -83, -177, 989, 927 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EEBKME+AdvP4C4E74 FontSubset: true FirstChar: 1 LastChar: 4 FontDescriptor: FontName: EEBKME+AdvP4C4E74 Flags: Symbolic FontBBox: -20, -958, 1114, 770 FontFile3: true EncodingDictionary: Differences: true Font: BaseFont: EEBIIB+AdvTTa9c1b374+20 FontSubset: true FirstChar: 2 LastChar: 151 FontDescriptor: FontName: EEBIIB+AdvTTa9c1b374+20 Flags: Symbolic FontBBox: -239, -218, 1166, 937 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: EEBLKB+AdvTTfac587ca.B FontSubset: true FirstChar: 49 LastChar: 85 FontDescriptor: FontName: EEBLKB+AdvTTfac587ca.B Flags: Nonsymbolic FontBBox: -72, -177, 1062, 958 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EEEFPO+AdvTT9c438aa4.BI FontSubset: true FirstChar: 80 LastChar: 80 FontDescriptor: FontName: EEEFPO+AdvTT9c438aa4.BI Flags: Nonsymbolic FontBBox: -83, -177, 1010, 947 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EEBLJA+AdvTTc0096231+22 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: EEBLJA+AdvTTc0096231+22 Flags: Symbolic FontBBox: -10, -208, 1281, 906 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true XMP: VoR 10.1111/jvim.17036 10.1111/jvim.17036 10.1111/(ISSN)1939-1676 3 Peripheral and intestinal T lymphocyte subsets in dogs with chronic inflammatory enteropathy Pages: Page: Label: 1437 Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 119, 592, 120, 604 Destination: 422 Annotation: Subtype: Link Rect: 119, 597, 125, 610 Destination: 422 Annotation: Subtype: Link Rect: 127, 596, 136, 604 Annotation: Subtype: Link Rect: 275, 592, 276, 604 Destination: 422 Annotation: Subtype: Link Rect: 275, 597, 281, 610 Destination: 422 Annotation: Subtype: Link Rect: 370, 592, 371, 604 Destination: 422 Annotation: Subtype: Link Rect: 370, 597, 376, 610 Destination: 422 Annotation: Subtype: Link Rect: 154, 574, 155, 586 Destination: 422 Annotation: Subtype: Link Rect: 154, 579, 160, 591 Destination: 422 Annotation: Subtype: Link Rect: 163, 578, 171, 586 Annotation: Subtype: Link Rect: 346, 574, 347, 586 Destination: 422 Annotation: Subtype: Link Rect: 346, 579, 353, 591 Destination: 422 Annotation: Subtype: Link Rect: 485, 574, 486, 586 Destination: 422 Annotation: Subtype: Link Rect: 485, 579, 491, 591 Destination: 422 Annotation: Subtype: Link Rect: 130, 556, 131, 568 Destination: 422 Annotation: Subtype: Link Rect: 130, 561, 136, 574 Destination: 422 Annotation: Subtype: Link Rect: 295, 556, 297, 568 Destination: 422 Annotation: Subtype: Link Rect: 295, 561, 302, 574 Destination: 422 Annotation: Subtype: Link Rect: 65, 357, 120, 364 Annotation: Subtype: Link Rect: 205, 72, 382, 79 Annotation: Subtype: Link Rect: 410, 32, 518, 39 Thumb: true Page: Label: 1438 Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 201, 555, 210, 563 Destination: 183 Annotation: Subtype: Link Rect: 186, 542, 194, 550 Destination: 183 Annotation: Subtype: Link Rect: 92, 516, 105, 524 Destination: 183 Annotation: Subtype: Link Rect: 189, 490, 202, 498 Destination: 183 Annotation: Subtype: Link Rect: 218, 477, 226, 485 Destination: 183 Annotation: Subtype: Link Rect: 146, 425, 159, 433 Destination: 183 Annotation: Subtype: Link Rect: 75, 399, 82, 407 Destination: 183 Annotation: Subtype: Link Rect: 90, 360, 105, 368 Destination: 183 Annotation: Subtype: Link Rect: 61, 347, 76, 355 Destination: 183 Annotation: Subtype: Link Rect: 168, 334, 184, 342 Destination: 183 Annotation: Subtype: Link Rect: 64, 282, 72, 290 Destination: 183 Annotation: Subtype: Link Rect: 88, 243, 91, 251 Destination: 183 Annotation: Subtype: Link Rect: 77, 204, 92, 212 Destination: 183 Annotation: Subtype: Link Rect: 207, 178, 223, 186 Destination: 183 Annotation: Subtype: Link Rect: 245, 165, 248, 173 Destination: 183 Thumb: true Page: Label: 1439 Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 214, 724, 229, 732 Destination: 203 Annotation: Subtype: Link Rect: 273, 698, 288, 706 Destination: 203 Annotation: Subtype: Link Rect: 281, 464, 288, 472 Destination: 203 Annotation: Subtype: Link Rect: 204, 451, 211, 459 Destination: 203 Annotation: Subtype: Link Rect: 205, 386, 212, 394 Destination: 203 Annotation: Subtype: Link Rect: 104, 360, 111, 368 Destination: 203 Annotation: Subtype: Link Rect: 181, 191, 188, 199 Destination: 203 Annotation: Subtype: Link Rect: 331, 526, 336, 534 Destination: 40 Annotation: Subtype: Link Rect: 323, 373, 330, 381 Destination: 203 Annotation: Subtype: Link Rect: 426, 201, 431, 209 Destination: 72 Thumb: true Page: Label: 1440 Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 433, 256, 440, 264 Destination: 203 Annotation: Subtype: Link Rect: 322, 243, 329, 251 Destination: 203 Annotation: Subtype: Link Rect: 335, 217, 342, 225 Destination: 203 Annotation: Subtype: Link Rect: 463, 217, 470, 225 Destination: 203 Annotation: Subtype: Link Rect: 374, 149, 378, 157 Destination: 81 Annotation: Subtype: Link Rect: 385, 45, 389, 53 Destination: 81 Annotation: Subtype: Link Rect: 71, 693, 74, 701 Destination: 40 Annotation: Subtype: Link Rect: 217, 693, 220, 701 Destination: 40 Annotation: Subtype: Link Rect: 67, 679, 70, 687 Destination: 40 Annotation: Subtype: Link Rect: 218, 679, 221, 687 Destination: 40 Annotation: Subtype: Link Rect: 67, 665, 70, 673 Destination: 40 Annotation: Subtype: Link Rect: 224, 665, 227, 673 Destination: 40 Annotation: Subtype: Link Rect: 67, 651, 70, 659 Destination: 40 Annotation: Subtype: Link Rect: 71, 637, 74, 645 Destination: 40 Annotation: Subtype: Link Rect: 211, 637, 214, 645 Destination: 40 Annotation: Subtype: Link Rect: 73, 623, 75, 631 Destination: 40 Annotation: Subtype: Link Rect: 217, 623, 220, 631 Destination: 40 Annotation: Subtype: Link Rect: 65, 609, 68, 617 Destination: 40 Annotation: Subtype: Link Rect: 211, 609, 214, 617 Destination: 40 Annotation: Subtype: Link Rect: 71, 595, 74, 603 Destination: 40 Thumb: true Page: Label: 1441 Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 334, 45, 352, 53 Destination: 115 Thumb: true Page: Label: 1442 Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 79, 689, 85, 697 Destination: 203 Annotation: Subtype: Link Rect: 371, 672, 374, 679 Destination: 81 Annotation: Subtype: Link Rect: 371, 658, 374, 665 Destination: 81 Annotation: Subtype: Link Rect: 89, 647, 96, 655 Destination: 203 Annotation: Subtype: Link Rect: 371, 644, 374, 651 Destination: 81 Annotation: Subtype: Link Rect: 371, 630, 374, 637 Destination: 81 Annotation: Subtype: Link Rect: 371, 616, 374, 623 Destination: 81 Annotation: Subtype: Link Rect: 367, 602, 370, 609 Destination: 81 Annotation: Subtype: Link Rect: 260, 591, 263, 598 Destination: 81 Annotation: Subtype: Link Rect: 79, 576, 85, 583 Destination: 203 Annotation: Subtype: Link Rect: 371, 558, 374, 566 Destination: 81 Annotation: Subtype: Link Rect: 103, 548, 110, 555 Destination: 203 Annotation: Subtype: Link Rect: 371, 530, 374, 538 Destination: 81 Annotation: Subtype: Link Rect: 214, 259, 216, 267 Destination: 81 Annotation: Subtype: Link Rect: 387, 256, 390, 263 Destination: 81 Annotation: Subtype: Link Rect: 528, 256, 531, 263 Destination: 81 Annotation: Subtype: Link Rect: 213, 231, 216, 239 Destination: 81 Annotation: Subtype: Link Rect: 391, 200, 394, 207 Destination: 81 Annotation: Subtype: Link Rect: 532, 200, 535, 207 Destination: 81 Thumb: true Page: Label: 1443 Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 244, 682, 261, 690 Destination: 115 Annotation: Subtype: Link Rect: 67, 591, 72, 599 Destination: 127 Annotation: Subtype: Link Rect: 418, 695, 435, 703 Destination: 115 Annotation: Subtype: Link Rect: 403, 643, 413, 651 Destination: 115 Thumb: true Page: Label: 1444 Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 226, 266, 235, 274 Destination: 115 Annotation: Subtype: Link Rect: 436, 204, 447, 212 Destination: 183 Annotation: Subtype: Link Rect: 421, 152, 436, 160 Destination: 203 Annotation: Subtype: Link Rect: 356, 126, 371, 134 Destination: 203 Annotation: Subtype: Link Rect: 517, 126, 533, 134 Destination: 203 Annotation: Subtype: Link Rect: 325, 61, 341, 69 Destination: 203 Annotation: Subtype: Link Rect: 353, 644, 356, 651 Destination: 127 Annotation: Subtype: Link Rect: 134, 525, 137, 532 Destination: 127 Annotation: Subtype: Link Rect: 349, 532, 352, 540 Destination: 127 Annotation: Subtype: Link Rect: 134, 497, 137, 504 Destination: 127 Annotation: Subtype: Link Rect: 349, 504, 352, 511 Destination: 127 Annotation: Subtype: Link Rect: 528, 476, 531, 483 Destination: 127 Annotation: Subtype: Link Rect: 349, 448, 352, 455 Destination: 127 Annotation: Subtype: Link Rect: 353, 392, 356, 399 Destination: 127 Thumb: true Page: Label: 1445 Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 216, 724, 231, 732 Destination: 203 Annotation: Subtype: Link Rect: 153, 685, 168, 693 Destination: 203 Annotation: Subtype: Link Rect: 258, 685, 274, 693 Destination: 203 Annotation: Subtype: Link Rect: 186, 594, 193, 602 Destination: 203 Annotation: Subtype: Link Rect: 67, 568, 74, 576 Destination: 203 Annotation: Subtype: Link Rect: 281, 542, 288, 550 Destination: 203 Annotation: Subtype: Link Rect: 260, 451, 284, 459 Destination: 183 Annotation: Subtype: Link Rect: 211, 425, 227, 433 Destination: 203 Annotation: Subtype: Link Rect: 59, 412, 74, 420 Destination: 183 Annotation: Subtype: Link Rect: 239, 360, 255, 368 Destination: 203 Annotation: Subtype: Link Rect: 59, 269, 74, 277 Destination: 203 Annotation: Subtype: Link Rect: 95, 165, 102, 173 Destination: 183 Annotation: Subtype: Link Rect: 75, 139, 90, 147 Destination: 203 Annotation: Subtype: Link Rect: 94, 87, 101, 95 Destination: 203 Annotation: Subtype: Link Rect: 121, 48, 136, 56 Destination: 203 Annotation: Subtype: Link Rect: 520, 711, 527, 719 Destination: 203 Annotation: Subtype: Link Rect: 314, 633, 330, 641 Destination: 203 Annotation: Subtype: Link Rect: 434, 633, 440, 641 Destination: 210 Annotation: Subtype: Link Rect: 431, 581, 446, 589 Destination: 203 Annotation: Subtype: Link Rect: 515, 555, 531, 563 Destination: 203 Annotation: Subtype: Link Rect: 408, 516, 423, 524 Destination: 210 Annotation: Subtype: Link Rect: 328, 412, 340, 420 Destination: 183 Annotation: Subtype: Link Rect: 338, 321, 345, 329 Destination: 203 Annotation: Subtype: Link Rect: 387, 269, 402, 277 Destination: 210 Annotation: Subtype: Link Rect: 383, 243, 398, 251 Destination: 203 Annotation: Subtype: Link Rect: 322, 100, 337, 108 Destination: 203 Annotation: Subtype: Link Rect: 403, 87, 427, 95 Destination: 203 Annotation: Subtype: Link Rect: 429, 74, 436, 82 Destination: 203 Thumb: true Page: Label: 1446 Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 281, 724, 288, 732 Destination: 210 Annotation: Subtype: Link Rect: 93, 60, 101, 68 Annotation: Subtype: Link Rect: 103, 58, 246, 66 Annotation: Subtype: Link Rect: 114, 47, 123, 55 Annotation: Subtype: Link Rect: 125, 45, 268, 53 Thumb: true Page: Label: 1447 Sequence: 11 Thumb: true Page: Label: 1448 Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 395, 519, 467, 527 Thumb: true Checksum: 5c082988 Type: CRC32 Checksum: 5312269b4a51d9110d374c8bf37c84a3 Type: MD5 Checksum: 3de9cafe49c3748df939c295ab0dc5c64a5bcf6c Type: SHA-1 Checksum: 20f700f2998c31ecea6482f9583a03f2ce0254a33911a0f8ddedaac1eb9413f4 Type: SHA-256