643ddb04cd9afe5612d4df5e1c5783d7 pmc_11132137.pdf db7cb23cd8b4330d1baf9b5ea6733ee129716fc9 pmc_11132137.pdf 511ccc141dd24e9dc1e07a60207a23a87cda9d3091092e76e739357285029228 pmc_11132137.pdf Title: Robotic, transanal, and laparoscopic total mesorectal excision for locally advanced mid/low rectal cancer: European multicentre, propensity score-matched study Subject: DOI: 10.1093/bjsopen/zrae044; BJS Open, 8, 3, 2024-05-28.; Abstract: Background: Total mesorectal excision (TME) is the standard surgery for low/mid locally advanced rectal cancer. The aim of this study was to compare three minimally invasive surgical approaches for TME with primary anastomosis (laparoscopic TME, robotic TME, and transanal TME). Methods: Records of patients undergoing laparoscopic TME, robotic TME, or transanal TME between 2013 and 2022 according to standardized techniques in expert centres contributing to the European MRI and Rectal Cancer Surgery III (EuMaRCS-III) database were analysed. Propensity score matching was applied to compare the three groups with respect to the complication rate (primary outcome), conversion rate, postoperative recovery, and survival. Results: A total of 468 patients (mean(s.d.) age of 64.1(11) years) were included; 190 (40.6%) patients underwent laparoscopic TME, 141 (30.1%) patients underwent robotic TME, and 137 (29.3%) patients unde Keywords: Author: Nicola de’Angelis Creator: Servigistics Arbortext Advanced Print Publisher 11.1.4546/W-x64 Producer: PDFlib+PDI 9.0.7p3 (C++/Win64) CreationDate: Tue May 28 12:17:10 2024 CEST ModDate: Tue May 28 13:44:30 2024 CEST Custom Metadata: yes Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 10 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 267277 bytes Optimized: yes PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- YWXWYW+CaeciliaLTStd-Bold Type 1C Custom yes yes yes 1441 0 FIYRGN+CaeciliaLTStd-Roman Type 1C Custom yes yes yes 1444 0 KFYQSN+CaeciliaLTStd-Light Type 1C Custom yes yes yes 1447 0 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MIMEtype: application/pdf Profile: Linearized PDF, Tagged PDF PDFMetadata: Objects: 0 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: true NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: OneColumn PageMode: UseOutlines Language: en Outlines: Item: Title: Robotic, transanal, and laparoscopic total mesorectal excision for locally advanced mid/low rectal cancer: European multicentre, propensity score-matched study Destination: head1 Children: Item: Title: Introduction Destination: seczrae044-s0 Item: Title: Methods Destination: seczrae044-s1 Children: Item: Title: Study population Destination: seczrae044-s1.1 Item: Title: Study design Destination: seczrae044-s1.2 Item: Title: Study outcomes Destination: seczrae044-s1.3 Item: Title: Statistical analyses Destination: seczrae044-s1.4 Item: Title: Results Destination: seczrae044-s2 Item: Title: Discussion Destination: seczrae044-s3 Item: Title: Collaborators Destination: seczrae044-s4 Children: Item: Title: European MRI and Rectal Cancer Surgery (EuMaRCS) Study Group Destination: seczrae044-s4.1 Item: Title: Funding Destination: seczrae044-s4.2 Item: Title: Acknowledgements Destination: acknow Item: Title: Author contributions Destination: seczrae044-s5 Item: Title: Disclosure Destination: seczrae044-s6 Item: Title: Supplementary material Destination: seczrae044-s7 Item: Title: Data availability Destination: seczrae044-s8 Item: Title: References Destination: reflist Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 335 ImageHeight: 79 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: DDNFQY+CaeciliaLTStd-Italic FontSubset: true FirstChar: 1 LastChar: 14 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Marchegiani Aleix Martínez-Pérez Alberto Biondi Salvatore Pucciarelli Carlo Alberto Schena Gianluca Pellino Miquel Kraft Annabel S. van Lieshout Luca Morelli Alain Valverde Renato Micelli Lupinacci Segundo A. Gómez-Abril Roberto Persiani Jurriaan B. Tuynman Eloy Espin-Basany Frederic Ris on behalf of the European MRI and Rectal Cancer Surgery (EuMaRCS) Study Group DOI: 10.1093/bjsopen/zrae044; BJS Open, 8, 3, 2024-05-28.; Abstract: Background: Total mesorectal excision (TME) is the standard surgery for low/mid locally advanced rectal cancer. The aim of this study was to compare three minimally invasive surgical approaches for TME with primary anastomosis (laparoscopic TME, robotic TME, and transanal TME). Methods: Records of patients undergoing laparoscopic TME, robotic TME, or transanal TME between 2013 and 2022 according to standardized techniques in expert centres contributing to the European MRI and Rectal Cancer Surgery III (EuMaRCS-III) database were analysed. Propensity score matching was applied to compare the three groups with respect to the complication rate (primary outcome), conversion rate, postoperative recovery, and survival. Results: A total of 468 patients (mean(s.d.) age of 64.1(11) years) were included; 190 (40.6%) patients underwent laparoscopic TME, 141 (30.1%) patients underwent robotic TME, and 137 (29.3%) patients unde © The Author(s) 2024. Published by Oxford University Press on behalf of BJS Foundation Ltd. Journal BJS Open © The Author(s) 2024. 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