ca22ee9c3896c16cd0d4b711db46ce41 pmc_11242028.pdf 0350c5a7b53c1723a906945d6f8808df92376067 pmc_11242028.pdf ef9acf2698cfe3b0374f130bec04278248bcf4f92d307bf8386430d727055882 pmc_11242028.pdf Title: Adherence to Supervised and Unsupervised Exercise Programmes in Ageing Population with Intermittent Claudication: A Randomized Controlled Trial Subject: Background: Intermittent Claudication symptomatic peripheral arterial disease (ICSPAD) is associated with reduced mobility, functional capacity, and quality of life. Physical exercise is an effective non-pharmacological intervention for the management of ICSPAD. Adherence to exercise programs is challenging, due to the nature of the disease and the complex comorbidities associated with it. This study aimed to determine adherence to three supervised physical exercise programs (a walking intervention, strength intervention, and concurrent intervention) and an unsupervised exercise program (standard advice) in individuals with ICSPAD. Methods: In this clinical trial, 122 patients were divided into four groups based on the type of exercise program they followed: standard advice, walking intervention, strength intervention, and concurrent intervention. Results: The results revealed that while the demographic characteristics were similar, the strength intervention group had a younger mean age, and the walking group had a higher prevalence of hypertension and increased usage of anti-hypertensive drugs. Adherence to physical exercise and pedometer wearing was highest in the standard advice group. Logistic regression analysis showed lower odds of adherence to exercise and pedometer wearing in the intervention groups compared to the standard advice group. Adherence did not significantly vary across ankle-brachial index categories. Furthermore, there was no significant difference in adherence between the severity levels of intermittent claudication, though mild cases tended to exhibit higher adherence. Conclusions: The results show that the standard advice from healthcare professionals positively influences treatment adherence. Keywords: clinical trial; intermittent claudication; adherence; medical education and training; primary health care; vascular medicine; sports medicine Author: Cecilia Herrero-Alonso, Victor-Miguel López-Lifante, Anna Costa-Garrido, Guillem Pera, Maite Alzamora, Rosa Forés, Esau José Martínez-Ruíz, Juan López-Palencia, Luciana Moizé-Arcone, Ester Mateo-Aguilar, Vanesa Rodríguez-Sales, Marina Alventosa, Antonio Heras, Marta Valverde, Concepció Violán and Pere Torán-Monserrat Creator: LaTeX with hyperref Producer: pdfTeX-1.40.25 CreationDate: Thu Jul 11 14:27:59 2024 CEST ModDate: Thu Jul 11 14:30:31 2024 CEST Custom Metadata: no Metadata Stream: no Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 14 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 374997 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- RFSHBY+URWPalladioL-Bold Type 1 Custom yes yes yes 10 0 DXDOPO+URWPalladioL-Roma Type 1 Custom yes yes yes 16 0 KZNWQK+URWPalladioL-Ital Type 1 Custom yes yes yes 21 0 XPUSBJ+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 37 0 BSDWLC+TimesNewRomanPSMT Type 1C WinAnsi yes yes no 40 0 IKKWKP+CMSY10 Type 1 Builtin yes yes yes 69 0 WVWPDJ+PazoMath-Italic Type 1 Builtin yes yes yes 77 0 RLYTRW+CMMI10 Type 1 Builtin yes yes yes 85 0 WBVKDJ+URWPalladioL-BoldItal Type 1 Custom yes yes yes 93 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-02-06 02:50:03 CET RepresentationInformation: pmc_11242028.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-01-17 02:40:07 CET Size: 374997 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 262 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: section.1 Item: Title: Materials and Methods Destination: section.2 Children: Item: Title: Design, Setting, and Study Population Destination: subsection.2.1 Item: Title: Participant Recruitment, Follow-Up Destination: subsection.2.2 Item: Title: Randomization Destination: subsection.2.3 Item: Title: Intervention Programs and Control Group on Physical Exercise Destination: subsection.2.4 Item: Title: Main Outcomes Destination: subsection.2.5 Item: Title: Outcome Measures Destination: subsection.2.6 Item: Title: Sample Size Destination: subsection.2.7 Item: Title: Statistical Analysis Destination: subsection.2.8 Item: Title: Ethics Destination: subsection.2.9 Item: Title: Results Destination: section.3 Children: Item: Title: Study Population Characteristics Destination: subsection.3.1 Item: Title: Adherence to Physical Exercise Programs Destination: subsection.3.2 Item: Title: Adherence to Physical Exercise and Ankle-Brachial Index Destination: subsection.3.3 Item: Title: Adherence to Physical Exercise and Claudication Walk Test Destination: subsection.3.4 Item: Title: Discussion Destination: section.4 Item: Title: Conclusions Destination: section.5 Item: Title: References Destination: section.6 Info: Title: Adherence to Supervised and Unsupervised Exercise Programmes in Ageing Population with Intermittent Claudication: A Randomized Controlled Trial Author: Cecilia Herrero-Alonso, Victor-Miguel López-Lifante, Anna Costa-Garrido, Guillem Pera, Maite Alzamora, Rosa Forés, Esau José Martínez-Ruíz, Juan López-Palencia, Luciana Moizé-Arcone, Ester Mateo-Aguilar, Vanesa Rodríguez-Sales, Marina Alventosa, Antonio Heras, Marta Valverde, Concepció Violán and Pere Torán-Monserrat Subject: Background: Intermittent Claudication symptomatic peripheral arterial disease (ICSPAD) is associated with reduced mobility, functional capacity, and quality of life. Physical exercise is an effective non-pharmacological intervention for the management of ICSPAD. Adherence to exercise programs is challenging, due to the nature of the disease and the complex comorbidities associated with it. This study aimed to determine adherence to three supervised physical exercise programs (a walking intervention, strength intervention, and concurrent intervention) and an unsupervised exercise program (standard advice) in individuals with ICSPAD. Methods: In this clinical trial, 122 patients were divided into four groups based on the type of exercise program they followed: standard advice, walking intervention, strength intervention, and concurrent intervention. Results: The results revealed that while the demographic characteristics were similar, the strength intervention group had a younger mean age, and the walking group had a higher prevalence of hypertension and increased usage of anti-hypertensive drugs. Adherence to physical exercise and pedometer wearing was highest in the standard advice group. Logistic regression analysis showed lower odds of adherence to exercise and pedometer wearing in the intervention groups compared to the standard advice group. Adherence did not significantly vary across ankle-brachial index categories. Furthermore, there was no significant difference in adherence between the severity levels of intermittent claudication, though mild cases tended to exhibit higher adherence. Conclusions: The results show that the standard advice from healthcare professionals positively influences treatment adherence. 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