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Title:           Pan-Genome Provides Insights into Vibrio Evolution and Adaptation to Deep-Sea Hydrothermal Vents
Subject:         DOI: 10.1093/gbe/evae131; Genome Biology and Evolution, 16, 7, 2024-07-15.; Abstract: This study delves into the genomic features of 10 Vibrio strains collected from deep-sea hydrothermal vents in the Pacific Ocean, providing insights into their evolutionary history and ecological adaptations. Through sequencing and pan-genome analysis involving 141 Vibrio species, we found that deep-sea strains exhibit larger genomes with unique gene distributions, suggesting adaptation to the vent environment. The phylogenomic reconstruction of the investigated isolates revealed the presence of 2 main clades: The first is monophyletic, consisting exclusively of Vibrio alginolyticus, while the second forms a monophyletic clade comprising both Vibrio antiquarius and Vibrio diabolicus species, which were previously isolated from deep-sea vents. All strains carry virulence and antibiotic resistance genes related to those found in human pathogenic Vibrio species which may play a wider ecological role other than host infection in these environments. In addition, functional genomic analysis identified genes potentially related to deep-sea survival and stress response, alongside candidate genes encoding for novel antimicrobial agents. Ultimately, the pan-genome we generated represents a valuable resource for future studies investigating the taxonomy, evolution, and ecology of Vibrio species.
Keywords:        Vibrio; deep-sea hydrothermal vents; pan-genome; antibiotic resistance genes; virulence factors; comparative genomics
Author:          Emanuele Bosi
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      Title: Pan-Genome Provides Insights into Vibrio Evolution and Adaptation to Deep-Sea Hydrothermal Vents
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        Title: Materials and Methods
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          Title: Vibrio Strains Isolation and Sequencing
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          Title: Genome Analysis
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          Title: Pan-genome Analysis
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          Title: Phylogenetic Analysis of the Clade Vibrio alginolyticus
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          Title: Interaction With Bivalves
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        Title: Results
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         Item: 
          Title: Sequencing and Assembly of Vibrio spp. From Deep-Sea Vents
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          Title: The Pan-Genome of the Genus Vibrio
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          Title: Phylogenomics of Vibrio
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