353314ada1ec24ec5516a188c29962bc pmc_11303006.pdf 25f20c283a28fa1fbdf79ca15cffee1d1cef1410 pmc_11303006.pdf 447fca59f9881e2d45a185d86060730ebcee2b03ac0cda43fdee6d14e605bf59 pmc_11303006.pdf Title: Comparison of two bundles for reducing surgical site infection in colorectal surgery: multicentre cohort study Subject: DOI: 10.1093/bjsopen/zrae080; BJS Open, 8, 4, 2024-08-06.; Abstract: Background: There is controversy regarding the maximum number of elements that can be included in a surgical site infection prevention bundle. In addition, it is unclear whether a bundle of this type can be implemented at a multicentre level. Methods: A pragmatic, multicentre cohort study was designed to analyse surgical site infection rates in elective colorectal surgery after the sequential implementation of two preventive bundle protocols. Secondary outcomes were to determine compliance with individual measures and to establish their effectiveness, duration of stay, microbiology and 30-day mortality rate. Results: A total of 32 205 patients were included. A 50% reduction in surgical site infection was achieved after the implementation of two sequential sets of bundles: from 18.16% in the Baseline group to 10.03% with Bundle-1 and 8.19% with Bundle-2. Bundle-2 reduced superficial-surgical site infection (OR 0.74 Keywords: Author: Miriam Flores-Yelamos Creator: Servigistics Arbortext Advanced Print Publisher 11.1.4546/W-x64 Producer: PDFlib+PDI 9.0.7p3 (C++/Win64) CreationDate: Mon Aug 5 18:11:22 2024 CEST ModDate: Tue Aug 6 05:02:22 2024 CEST Custom Metadata: yes Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 12 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 263764 bytes Optimized: yes PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- KUDQZL+CaeciliaLTStd-Bold Type 1C Custom yes yes yes 2248 0 HXKCXO+CaeciliaLTStd-Roman Type 1C Custom yes yes yes 2251 0 YFMIOY+CaeciliaLTStd-Light Type 1C Custom yes yes yes 2254 0 ADPUJQ+CaeciliaLTStd-LightItalic Type 1C Custom yes yes yes 2257 0 TUALKI+CaeciliaLTStd-Heavy Type 1C Custom yes yes yes 2260 0 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PrintArea: CropBox PageClip: CropBox PageLayout: OneColumn PageMode: UseOutlines Language: en Outlines: Item: Title: Comparison of two bundles for reducing surgical site infection in colorectal surgery: multicentre cohort study Destination: head1 Children: Item: Title: Introduction Destination: seczrae080-s0 Item: Title: Methods Destination: seczrae080-s1 Children: Item: Title: Setting and patients Destination: seczrae080-s1.1 Item: Title: Data source, definitions, study outcomes and variables Destination: seczrae080-s1.2 Item: Title: Intervention Destination: seczrae080-s1.3 Item: Title: Statistical analysis Destination: seczrae080-s1.4 Item: Title: Ethical issues Destination: seczrae080-s1.5 Item: Title: Results Destination: seczrae080-s2 Children: Item: Title: SSI rates and bundle compliance Destination: seczrae080-s2.1 Item: Title: Individual effect of bundle measures on SSI rates Destination: seczrae080-s2.2 Item: Title: Secondary outcomes Destination: seczrae080-s2.3 Item: Title: Discussion Destination: seczrae080-s3 Item: Title: Collaborators Destination: seczrae080-s4 Children: Item: Title: VINCat Colorectal Surveillance Team Destination: seczrae080-s4a Item: Title: Funding Destination: seczrae080-s5 Item: Title: Acknowledgements Destination: acknow Item: Title: Disclosure Destination: seczrae080-s6 Item: Title: Supplementary material Destination: seczrae080-s7 Item: Title: Data availability Destination: seczrae080-s8 Item: Title: Author contributions Destination: seczrae080-s9 Item: Title: Institutional review board statement Destination: seczrae080-s10 Item: Title: References Destination: reflist Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 335 ImageHeight: 79 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: ADPUJQ+CaeciliaLTStd-LightItalic FontSubset: true FirstChar: 1 LastChar: 59 FontDescriptor: FontName: 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BaseFont: YFMIOY+CaeciliaLTStd-Light FontSubset: true FirstChar: 1 LastChar: 99 FontDescriptor: FontName: YFMIOY+CaeciliaLTStd-Light Flags: Nonsymbolic FontBBox: -164, -266, 1130, 908 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true XMP: uuid:dec5a02c-e6d5-4b73-b4f6-63baa01b8adb uuid:2800FE61-82D5-EE71-846A-2678755177F9 True PDFlib+PDI 9.0.7p3 (C++/Win64) application/pdf 10.1093/bjsopen/zrae080 en Oxford University Press Comparison of two bundles for reducing surgical site infection in colorectal surgery: multicentre cohort study Miriam Flores-Yelamos Aina Gomila-Grange Josep M. Badia Alexander Almendral Ana Vázquez David Parés Marta Pascual Enric Limón Miquel Pujol Montserrat Juvany members of the VINCat Colorectal Surveillance Team DOI: 10.1093/bjsopen/zrae080; BJS Open, 8, 4, 2024-08-06.; Abstract: Background: There is controversy regarding the maximum number of elements that can be included in a surgical site infection prevention bundle. In addition, it is unclear whether a bundle of this type can be implemented at a multicentre level. Methods: A pragmatic, multicentre cohort study was designed to analyse surgical site infection rates in elective colorectal surgery after the sequential implementation of two preventive bundle protocols. Secondary outcomes were to determine compliance with individual measures and to establish their effectiveness, duration of stay, microbiology and 30-day mortality rate. Results: A total of 32 205 patients were included. A 50% reduction in surgical site infection was achieved after the implementation of two sequential sets of bundles: from 18.16% in the Baseline group to 10.03% with Bundle-1 and 8.19% with Bundle-2. Bundle-2 reduced superficial-surgical site infection (OR 0.74 © The Author(s) 2024. Published by Oxford University Press on behalf of BJS Foundation Ltd. Journal BJS Open © The Author(s) 2024. 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