14af0737868ba9b52f127110ce34e2f0 322323.pdf 52b3358d8f44f84778491c95880c7b32a89e25f6 322323.pdf 1008aac521354b135effc563a8656c245663471a7ec90038d2d895a0d32bc483 322323.pdf Title: Inferring disease course from differential exon usage in the wide titinopathy spectrum Subject: Ann Clin Transl Neurol 2024.11:2745-2755 Creator: Arbortext Advanced Print Publisher 9.1.531/W Unicode Producer: Acrobat Distiller 15.0 (Windows); modified using iText 4.2.0 by 1T3XT CreationDate: Wed Oct 16 13:07:32 2024 CEST ModDate: Tue Feb 17 09:39:42 2026 CET Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 752253 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- KDDHKP+AdvPSSym Type 1C WinAnsi yes yes no 44 0 KDDHJM+AdvTTec369687 Type 1C WinAnsi yes yes no 84 0 KDDHLA+AdvPSFT-LI Type 1C WinAnsi yes yes no 45 0 KDDHJN+AdvMINION-B Type 1C WinAnsi yes yes no 46 0 KDDHKO+AdvMINION-R Type 1C MacRoman yes yes no 47 0 KDDGIM+AdvPSFT-R Type 1C WinAnsi yes yes no 48 0 KDDGIN+AdvPSFTBL Type 1C MacRoman yes yes no 49 0 KDDGPM+AdvP4C4E59 Type 1C Custom yes yes yes 141 0 KDDHIJ+AdvPSFT-L Type 1C Custom yes yes no 51 0 KDDHJK+AdvTT3713a231+20 Type 1C WinAnsi yes yes no 142 0 KDDHJL+AdvPSFT-B Type 1C WinAnsi yes yes no 54 0 KDDHMC+AdvMINION-I Type 1C WinAnsi yes yes no 50 0 KDDHMA+AdvPSFT-BI Type 1C WinAnsi yes yes no 52 0 KDDHMB+AdvTTec369687+20 Type 1C WinAnsi yes yes no 53 0 Times-Roman Type 1 WinAnsi no no no 5 0 KDEAJN+AdvSPSASORT Type 1C Custom yes yes no 140 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2026-02-18 04:06:16 CET RepresentationInformation: 322323.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2026-02-17 10:20:39 CET Size: 752253 Format: PDF Version: 1.7 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ErrorMessage: Invalid indirect destination - referenced object 'emaill_2344448_1' cannot be found ID: PDF-HUL-149 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'emaill_2344448_1' cannot be found ID: PDF-HUL-122 Offset: 727427 MIMEtype: application/pdf PDFMetadata: Objects: 0 FreeObjects: 2 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Abstract Destination: head2_2137527 Item: Title: Introduction Destination: head3_967975 Item: Title: Material and Methods Destination: head4_2106700 Children: Item: Title: Clinical features analysis Destination: head5_2191050 Item: Title: Molecular genetic analysis Destination: head6_832522 Item: Title: RNA„-„sequencing„ on samples cohort Destination: head7_1296448 Item: Title: Results Destination: head8_621647 Children: Item: Title: Patients deceased before birth or in the perinatal period Destination: head9_1127748 Item: Title: Congenital cases improving with’age Destination: head10_2266474 Item: Title: Congenital cases worsening with’age Destination: head11_2097772 Item: Title: An unlikely case of titinopathy Destination: head12_1886897 Item: Title: Discussion Destination: head13_495122 Children: Item: Title: acn352189-fig-0001 Destination: lacn352189-fig-0001 Item: Title: acn352189-fig-0002 Destination: lacn352189-fig-0002 Item: Title: Conclusions Destination: head14_1212097 Item: Title: Acknowledgements Destination: head15_1886898 Item: Title: Funding Information Destination: head16_2139949 Item: Title: Conflict of Interest Destination: head17_579472 Item: Title: Author Contributions Destination: head18_748173 Children: Item: Title: Data Availability Statement Destination: head19_1254274 Item: Title: References Destination: head20_1507325 Children: Item: Title: acn352189-bib-0001 Destination: lacn352189-bib-0001 Item: Title: acn352189-bib-0002 Destination: lacn352189-bib-0002 Item: Title: acn352189-bib-0003 Destination: lacn352189-bib-0003 Item: Title: acn352189-bib-0004 Destination: lacn352189-bib-0004 Item: Title: acn352189-bib-0005 Destination: lacn352189-bib-0005 Item: Title: acn352189-bib-0006 Destination: lacn352189-bib-0006 Item: Title: acn352189-bib-0007 Destination: lacn352189-bib-0007 Item: Title: acn352189-bib-0008 Destination: lacn352189-bib-0008 Item: Title: acn352189-bib-0009 Destination: lacn352189-bib-0009 Item: Title: acn352189-bib-0010 Destination: lacn352189-bib-0010 Item: Title: acn352189-bib-0011 Destination: lacn352189-bib-0011 Item: Title: acn352189-bib-0012 Destination: lacn352189-bib-0012 Item: Title: acn352189-bib-0013 Destination: lacn352189-bib-0013 Item: Title: acn352189-bib-0014 Destination: lacn352189-bib-0014 Item: Title: acn352189-bib-0015 Destination: lacn352189-bib-0015 Item: Title: acn352189-bib-0016 Destination: lacn352189-bib-0016 Item: Title: acn352189-bib-0017 Destination: lacn352189-bib-0017 Item: Title: acn352189-bib-0018 Destination: lacn352189-bib-0018 Item: Title: acn352189-bib-0019 Destination: lacn352189-bib-0019 Item: Title: acn352189-bib-0020 Destination: lacn352189-bib-0020 Item: Title: acn352189-bib-0021 Destination: lacn352189-bib-0021 Item: Title: acn352189-bib-0022 Destination: lacn352189-bib-0022 Item: Title: acn352189-bib-0023 Destination: lacn352189-bib-0023 Item: Title: acn352189-bib-0024 Destination: lacn352189-bib-0024 Item: Title: acn352189-bib-0025 Destination: lacn352189-bib-0025 Item: Title: acn352189-bib-0026 Destination: lacn352189-bib-0026 Item: Title: acn352189-bib-0027 Destination: lacn352189-bib-0027 Item: Title: acn352189-bib-0028 Destination: lacn352189-bib-0028 Item: Title: acn352189-bib-0029 Destination: lacn352189-bib-0029 Item: Title: acn352189-bib-0030 Destination: lacn352189-bib-0030 Item: Title: acn352189-bib-0031 Destination: lacn352189-bib-0031 Item: Title: acn352189-bib-0032 Destination: lacn352189-bib-0032 Item: Title: acn352189-bib-0033 Destination: lacn352189-bib-0033 Item: Title: acn352189-bib-0034 Destination: lacn352189-bib-0034 Item: Title: acn352189-bib-0035 Destination: lacn352189-bib-0035 Item: Title: acn352189-bib-0036 Destination: lacn352189-bib-0036 Item: Title: acn352189-bib-0037 Destination: lacn352189-bib-0037 Item: Title: acn352189-bib-0038 Destination: lacn352189-bib-0038 Item: Title: acn352189-bib-0039 Destination: lacn352189-bib-0039 Item: Title: acn352189-bib-0040 Destination: lacn352189-bib-0040 Item: Title: acn352189-supitem Destination: lacn352189-supitem Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 228 ImageHeight: 45 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 228 ImageHeight: 45 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1966 ImageHeight: 779 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Intent: Perceptual Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1961 ImageHeight: 1943 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Intent: Perceptual Fonts: Type1: Font: BaseFont: KDDHKP+AdvPSSym FontSubset: true FirstChar: 170 LastChar: 170 FontDescriptor: FontName: KDDHKP+AdvPSSym Flags: Nonsymbolic FontBBox: -177, -291, 1083, 1010 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: KDEAJN+AdvSPSASORT FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: KDEAJN+AdvSPSASORT Flags: Symbolic FontBBox: -281, -437, 1343, 989 FontFile3: true EncodingDictionary: Differences: true Font: BaseFont: KDDHLA+AdvPSFT-LI FontSubset: true FirstChar: 46 LastChar: 121 FontDescriptor: FontName: KDDHLA+AdvPSFT-LI Flags: Nonsymbolic FontBBox: -135, -239, 1031, 781 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: KDDGPM+AdvP4C4E59 FontSubset: true FirstChar: 1 LastChar: 160 FontDescriptor: FontName: KDDGPM+AdvP4C4E59 Flags: Symbolic FontBBox: -31, -250, 1000, 750 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: KDDHJN+AdvMINION-B FontSubset: true FirstChar: 46 LastChar: 118 FontDescriptor: FontName: KDDHJN+AdvMINION-B Flags: Nonsymbolic FontBBox: -145, -239, 1145, 750 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: KDDHJK+AdvTT3713a231+20 FontSubset: true FirstChar: 151 LastChar: 151 FontDescriptor: FontName: KDDHJK+AdvTT3713a231+20 Flags: Nonsymbolic FontBBox: -468, -208, 1708, 843 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: KDDHKO+AdvMINION-R FontSubset: true FirstChar: 37 LastChar: 223 FontDescriptor: FontName: KDDHKO+AdvMINION-R Flags: Serif, Nonsymbolic FontBBox: -135, -239, 1104, 750 FontFile3: true Encoding: MacRomanEncoding Font: BaseFont: KDDGIM+AdvPSFT-R FontSubset: true FirstChar: 35 LastChar: 122 FontDescriptor: FontName: KDDGIM+AdvPSFT-R Flags: Nonsymbolic FontBBox: -166, -239, 1000, 802 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: KDDGIN+AdvPSFTBL FontSubset: true FirstChar: 45 LastChar: 223 FontDescriptor: FontName: KDDGIN+AdvPSFTBL Flags: Nonsymbolic FontBBox: -156, -239, 1000, 791 FontFile3: true Encoding: MacRomanEncoding Font: BaseFont: KDDHMC+AdvMINION-I FontSubset: true FirstChar: 48 LastChar: 120 FontDescriptor: FontName: KDDHMC+AdvMINION-I Flags: Nonsymbolic FontBBox: -135, -239, 1104, 750 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: KDDHIJ+AdvPSFT-L FontSubset: true FirstChar: 30 LastChar: 148 FontDescriptor: FontName: KDDHIJ+AdvPSFT-L Flags: Nonsymbolic FontBBox: -145, -239, 1000, 770 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: KDDHJM+AdvTTec369687 FontSubset: true FirstChar: 43 LastChar: 62 FontDescriptor: FontName: KDDHJM+AdvTTec369687 Flags: Nonsymbolic FontBBox: -72, -208, 927, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: KDDHMA+AdvPSFT-BI FontSubset: true FirstChar: 65 LastChar: 121 FontDescriptor: FontName: KDDHMA+AdvPSFT-BI Flags: Nonsymbolic FontBBox: -166, -239, 1083, 791 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: KDDHMB+AdvTTec369687+20 FontSubset: true FirstChar: 150 LastChar: 150 FontDescriptor: FontName: KDDHMB+AdvTTec369687+20 Flags: Nonsymbolic FontBBox: -208, -208, 1062, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: KDDHJL+AdvPSFT-B FontSubset: true FirstChar: 40 LastChar: 150 FontDescriptor: FontName: KDDHJL+AdvPSFT-B Flags: Nonsymbolic FontBBox: -156, -239, 1000, 791 FontFile3: true Encoding: WinAnsiEncoding XMP: application/pdfdoi:10.1002/acn3.52189 10.1002/acn3.52189https://doi.org/10.1002/acn3.52189 2024-08-28trueonlinelibrary.wiley.com10.1002/acn3.52189 onlinelibrary.wiley.comtrue10.1002/acn3.521892024-08-28 VoR Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 175, 638, 178, 648 Annotation: Subtype: Link Rect: 175, 637, 178, 647 Annotation: Subtype: Link Rect: 178, 637, 185, 648 Annotation: Subtype: Link Rect: 237, 626, 240, 636 Annotation: Subtype: Link Rect: 237, 625, 240, 635 Annotation: Subtype: Link Rect: 240, 625, 247, 636 Annotation: Subtype: Link Rect: 498, 614, 501, 624 Annotation: Subtype: Link Rect: 498, 613, 501, 623 Annotation: Subtype: Link Rect: 501, 613, 508, 624 Annotation: Subtype: Link Rect: 420, 590, 423, 600 Annotation: Subtype: Link Rect: 420, 589, 423, 599 Annotation: Subtype: Link Rect: 423, 590, 431, 601 Annotation: Subtype: Link Rect: 289, 566, 292, 576 Annotation: Subtype: Link Rect: 289, 565, 292, 575 Annotation: Subtype: Link Rect: 292, 566, 299, 577 Annotation: Subtype: Link Rect: 395, 566, 398, 576 Annotation: Subtype: Link Rect: 395, 565, 398, 575 Annotation: Subtype: Link Rect: 398, 566, 405, 577 Annotation: Subtype: Link Rect: 227, 554, 230, 564 Annotation: Subtype: Link Rect: 227, 553, 230, 563 Annotation: Subtype: Link Rect: 230, 554, 237, 565 Annotation: Subtype: Link Rect: 127, 115, 197, 123 Destination: null Annotation: Subtype: Link Rect: 57, 105, 89, 112 Destination: null Annotation: Subtype: Link Rect: 214, 51, 303, 57 Annotation: Subtype: Link Rect: 519, 782, 595, 767 Thumb: true Page: Label: 2 Annotations: Annotation: Subtype: Link Rect: 105, 441, 114, 450 Destination: 137 Annotation: Subtype: Link Rect: 167, 393, 170, 402 Destination: 137 Annotation: Subtype: Link Rect: 104, 357, 113, 366 Destination: 137 Annotation: Subtype: Link Rect: 129, 309, 137, 319 Destination: 137 Annotation: Subtype: Link Rect: 104, 213, 111, 223 Destination: 170 Annotation: Subtype: Link Rect: 104, 213, 111, 223 Destination: 170 Annotation: Subtype: Link Rect: 104, 213, 111, 223 Destination: 170 Annotation: Subtype: Link Rect: 104, 213, 117, 223 Destination: 170 Annotation: Subtype: Link Rect: 110, 166, 120, 175 Destination: 170 Annotation: Subtype: Link Rect: 110, 166, 120, 175 Destination: 170 Annotation: Subtype: Link Rect: 110, 166, 120, 175 Destination: 170 Annotation: Subtype: Link Rect: 110, 166, 127, 175 Destination: 170 Annotation: Subtype: Link Rect: 134, 142, 141, 151 Destination: 170 Annotation: Subtype: Link Rect: 386, 476, 396, 486 Destination: 170 Annotation: Subtype: Link Rect: 386, 476, 396, 486 Destination: 170 Annotation: Subtype: Link Rect: 386, 476, 396, 486 Destination: 170 Annotation: Subtype: Link Rect: 386, 476, 403, 486 Destination: 170 Annotation: Subtype: Link Rect: 348, 441, 355, 450 Destination: 170 Annotation: Subtype: Link Rect: 471, 405, 478, 414 Destination: 170 Annotation: Subtype: Link Rect: 412, 357, 435, 366 Destination: 170 Annotation: Subtype: Link Rect: 454, 285, 477, 295 Destination: 170 Annotation: Subtype: Link Rect: 531, 261, 538, 271 Destination: 170 Thumb: true Page: Label: 3 Annotations: Annotation: Subtype: Link Rect: 269, 570, 278, 580 Destination: 242 Annotation: Subtype: Link Rect: 162, 272, 258, 281 Destination: 242 Annotation: Subtype: Link Rect: 123, 260, 132, 269 Destination: 242 Annotation: Subtype: Link Rect: 162, 260, 171, 269 Destination: 242 Annotation: Subtype: Link Rect: 277, 84, 284, 94 Destination: 170 Annotation: Subtype: Link Rect: 504, 682, 511, 692 Destination: 170 Annotation: Subtype: Link Rect: 475, 658, 482, 668 Destination: 170 Annotation: Subtype: Link Rect: 375, 475, 380, 484 Destination: 96 Annotation: Subtype: Link Rect: 402, 475, 406, 484 Destination: 100 Annotation: Subtype: Link Rect: 337, 463, 346, 472 Destination: 242 Thumb: true Page: Label: 4 Thumb: true Page: Label: 5 Thumb: true Page: Label: 6 Annotations: Annotation: Subtype: Link Rect: 137, 599, 144, 608 Destination: 170 Annotation: Subtype: Link Rect: 205, 558, 214, 568 Destination: 242 Annotation: Subtype: Link Rect: 124, 427, 133, 436 Destination: 242 Annotation: Subtype: Link Rect: 343, 694, 346, 704 Destination: 137 Annotation: Subtype: Link Rect: 373, 539, 377, 548 Destination: 137 Annotation: Subtype: Link Rect: 382, 479, 389, 488 Destination: 170 Annotation: Subtype: Link Rect: 509, 451, 518, 460 Destination: 242 Annotation: Subtype: Link Rect: 310, 439, 319, 448 Destination: 242 Annotation: Subtype: Link Rect: 335, 343, 339, 353 Destination: 121 Annotation: Subtype: Link Rect: 360, 343, 365, 353 Destination: 130 Annotation: Subtype: Link Rect: 394, 343, 403, 353 Destination: 242 Annotation: Subtype: Link Rect: 527, 260, 532, 269 Destination: 121 Annotation: Subtype: Link Rect: 419, 156, 426, 166 Destination: 170 Thumb: true Page: Label: 7 Annotations: Annotation: Subtype: Link Rect: 222, 242, 229, 252 Destination: 170 Annotation: Subtype: Link Rect: 160, 146, 163, 156 Destination: 137 Annotation: Subtype: Link Rect: 92, 111, 95, 120 Destination: 137 Annotation: Subtype: Link Rect: 501, 206, 508, 216 Destination: 170 Thumb: true Page: Label: 8 Annotations: Annotation: Subtype: Link Rect: 338, 151, 347, 161 Destination: 242 Annotation: Subtype: Link Rect: 353, 155, 394, 165 Destination: 170 Thumb: true Page: Label: 9 Annotations: Annotation: Subtype: Link Rect: 149, 634, 159, 644 Destination: 242 Annotation: Subtype: Link Rect: 149, 634, 159, 644 Destination: 242 Annotation: Subtype: Link Rect: 149, 634, 159, 644 Destination: 242 Annotation: Subtype: Link Rect: 149, 634, 166, 644 Destination: 242 Annotation: Subtype: Link Rect: 179, 527, 186, 536 Destination: 242 Annotation: Subtype: Link Rect: 131, 336, 138, 345 Destination: 242 Annotation: Subtype: Link Rect: 85, 288, 101, 297 Destination: 242 Annotation: Subtype: Link Rect: 219, 252, 226, 261 Destination: 242 Annotation: Subtype: Link Rect: 416, 269, 503, 277 Annotation: Subtype: Link Rect: 435, 234, 515, 242 Annotation: Subtype: Link Rect: 510, 198, 520, 207 Annotation: Subtype: Link Rect: 316, 187, 355, 195 Annotation: Subtype: Link Rect: 316, 187, 355, 195 Annotation: Subtype: Link Rect: 316, 187, 380, 195 Annotation: Subtype: Link Rect: 433, 152, 491, 160 Annotation: Subtype: Link Rect: 433, 152, 491, 160 Annotation: Subtype: Link Rect: 433, 152, 507, 160 Annotation: Subtype: Link Rect: 433, 152, 507, 160 Annotation: Subtype: Link Rect: 433, 152, 507, 160 Annotation: Subtype: Link Rect: 316, 140, 336, 149 Annotation: Subtype: Link Rect: 316, 140, 336, 149 Annotation: Subtype: Link Rect: 316, 140, 342, 149 Annotation: Subtype: Link Rect: 398, 105, 472, 114 Thumb: true Page: Label: 10 Annotations: Annotation: Subtype: Link Rect: 139, 679, 220, 688 Annotation: Subtype: Link Rect: 161, 644, 235, 653 Annotation: Subtype: Link Rect: 93, 597, 186, 606 Annotation: Subtype: Link Rect: 139, 550, 194, 559 Annotation: Subtype: Link Rect: 167, 515, 260, 524 Annotation: Subtype: Link Rect: 236, 468, 291, 477 Annotation: Subtype: Link Rect: 175, 422, 240, 430 Annotation: Subtype: Link Rect: 140, 375, 213, 384 Annotation: Subtype: Link Rect: 278, 340, 289, 348 Annotation: Subtype: Link Rect: 80, 328, 169, 337 Annotation: Subtype: Link Rect: 224, 293, 283, 302 Annotation: Subtype: Link Rect: 224, 293, 283, 302 Annotation: Subtype: Link Rect: 224, 293, 283, 302 Annotation: Subtype: Link Rect: 80, 281, 96, 290 Annotation: Subtype: Link Rect: 80, 281, 96, 290 Annotation: Subtype: Link Rect: 80, 281, 116, 290 Annotation: Subtype: Link Rect: 80, 281, 116, 290 Annotation: Subtype: Link Rect: 80, 281, 120, 290 Annotation: Subtype: Link Rect: 281, 234, 291, 243 Annotation: Subtype: Link Rect: 80, 223, 107, 231 Annotation: Subtype: Link Rect: 80, 223, 107, 231 Annotation: Subtype: Link Rect: 80, 223, 127, 231 Annotation: Subtype: Link Rect: 80, 223, 127, 231 Annotation: Subtype: Link Rect: 80, 223, 143, 231 Annotation: Subtype: Link Rect: 94, 117, 164, 126 Annotation: Subtype: Link Rect: 385, 691, 432, 700 Annotation: Subtype: Link Rect: 385, 691, 432, 700 Annotation: Subtype: Link Rect: 385, 691, 452, 700 Annotation: Subtype: Link Rect: 385, 691, 452, 700 Annotation: Subtype: Link Rect: 385, 691, 477, 700 Annotation: Subtype: Link Rect: 459, 644, 535, 653 Annotation: Subtype: Link Rect: 411, 586, 490, 594 Annotation: Subtype: Link Rect: 339, 539, 422, 547 Annotation: Subtype: Link Rect: 339, 539, 422, 547 Annotation: Subtype: Link Rect: 339, 539, 442, 547 Annotation: Subtype: Link Rect: 339, 539, 442, 547 Annotation: Subtype: Link Rect: 339, 539, 467, 547 Annotation: Subtype: Link Rect: 339, 480, 397, 489 Annotation: Subtype: Link Rect: 339, 480, 397, 489 Annotation: Subtype: Link Rect: 339, 480, 413, 489 Annotation: Subtype: Link Rect: 339, 480, 413, 489 Annotation: Subtype: Link Rect: 339, 480, 437, 489 Annotation: Subtype: Link Rect: 339, 480, 437, 489 Annotation: Subtype: Link Rect: 339, 480, 485, 489 Annotation: Subtype: Link Rect: 442, 445, 530, 454 Annotation: Subtype: Link Rect: 326, 433, 361, 442 Annotation: Subtype: Link Rect: 377, 398, 484, 407 Annotation: Subtype: Link Rect: 400, 363, 458, 372 Annotation: Subtype: Link Rect: 400, 363, 458, 372 Annotation: Subtype: Link Rect: 400, 363, 474, 372 Annotation: Subtype: Link Rect: 400, 363, 474, 372 Annotation: Subtype: Link Rect: 400, 363, 494, 372 Annotation: Subtype: Link Rect: 400, 363, 494, 372 Annotation: Subtype: Link Rect: 400, 363, 501, 372 Annotation: Subtype: Link Rect: 326, 351, 367, 360 Annotation: Subtype: Link Rect: 385, 293, 464, 302 Annotation: Subtype: Link Rect: 459, 258, 532, 266 Annotation: Subtype: Link Rect: 446, 223, 503, 231 Annotation: Subtype: Link Rect: 446, 223, 503, 231 Annotation: Subtype: Link Rect: 446, 223, 518, 231 Annotation: Subtype: Link Rect: 446, 223, 518, 231 Annotation: Subtype: Link Rect: 446, 223, 518, 231 Annotation: Subtype: Link Rect: 326, 211, 345, 220 Annotation: Subtype: Link Rect: 326, 211, 345, 220 Annotation: Subtype: Link Rect: 326, 211, 350, 220 Annotation: Subtype: Link Rect: 497, 164, 531, 173 Annotation: Subtype: Link Rect: 326, 152, 386, 161 Annotation: Subtype: Link Rect: 412, 82, 507, 91 Thumb: true Page: Label: 11 Annotations: Annotation: Subtype: Link Rect: 211, 679, 261, 688 Annotation: Subtype: Link Rect: 72, 668, 139, 676 Annotation: Subtype: Link Rect: 231, 632, 261, 641 Annotation: Subtype: Link Rect: 72, 621, 99, 629 Annotation: Subtype: Link Rect: 72, 621, 99, 629 Annotation: Subtype: Link Rect: 72, 621, 115, 629 Annotation: Subtype: Link Rect: 72, 621, 115, 629 Annotation: Subtype: Link Rect: 72, 621, 139, 629 Annotation: Subtype: Link Rect: 72, 621, 139, 629 Annotation: Subtype: Link Rect: 72, 621, 143, 629 Annotation: Subtype: Link Rect: 174, 574, 231, 583 Annotation: Subtype: Link Rect: 174, 574, 231, 583 Annotation: Subtype: Link Rect: 174, 574, 246, 583 Annotation: Subtype: Link Rect: 174, 574, 246, 583 Annotation: Subtype: Link Rect: 174, 574, 271, 583 Annotation: Subtype: Link Rect: 174, 574, 271, 583 Annotation: Subtype: Link Rect: 174, 574, 275, 583 Annotation: Subtype: Link Rect: 220, 527, 250, 536 Annotation: Subtype: Link Rect: 72, 515, 189, 524 Annotation: Subtype: Link Rect: 85, 468, 134, 477 Annotation: Subtype: Link Rect: 85, 468, 134, 477 Annotation: Subtype: Link Rect: 85, 468, 159, 477 Annotation: Subtype: Link Rect: 385, 691, 439, 700 Annotation: Subtype: Link Rect: 385, 656, 465, 665 Annotation: Subtype: Link Rect: 509, 621, 520, 629 Annotation: Subtype: Link Rect: 317, 609, 368, 618 Annotation: Subtype: Link Rect: 419, 562, 514, 571 Thumb: true Checksum: 5c3e0e5e Type: CRC32 Checksum: 14af0737868ba9b52f127110ce34e2f0 Type: MD5 Checksum: 52b3358d8f44f84778491c95880c7b32a89e25f6 Type: SHA-1 Checksum: 1008aac521354b135effc563a8656c245663471a7ec90038d2d895a0d32bc483 Type: SHA-256