097cd0ddf61872bd10db53ad94fa6170 JouBioChe_a2025m1v301_108061.pdf db174a129a641648eee0c20e2262996083ac7908 JouBioChe_a2025m1v301_108061.pdf 2d4a97f2600c3ca270e7013c2152f586bd7a4c384acdfdea07737a12700631b8 JouBioChe_a2025m1v301_108061.pdf Title: p38α and p38β regulate osmostress-induced apoptosis Subject: Journal of Biological Chemistry, 301 (2025) 108061. doi:10.1016/j.jbc.2024.108061 Author: Nabil Ben Messaoud Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Sat Jan 4 13:16:52 2025 CET ModDate: Sat Jan 4 13:18:52 2025 CET Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 593.972 x 782.986 pts Page rot: 0 File size: 1890641 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- NFMHOE+AdvOTf0bf83d5.I Type 1C WinAnsi yes yes no 1024 0 NFMHPE+AdvOT46dcae81 Type 1C WinAnsi yes yes no 1037 0 NFMIED+AdvOT2bda31c3.B Type 1C WinAnsi yes yes no 1043 0 NFMIEE+AdvOT0d9ab1db.I Type 1C WinAnsi yes yes no 1045 0 NFMHIL+AdvOTce3d9a73 Type 1C WinAnsi yes yes no 1016 0 NFMHIM+AdvPS4BD310 Type 1C WinAnsi yes yes no 1019 0 NFMHIN+AdvOT07517017 Type 1C WinAnsi yes yes no 1021 0 NFMHLM+AdvOT65f8a23b.I Type 1C WinAnsi yes yes no 1004 0 NFMHLN+AdvOTe34d3d11 Type 1C WinAnsi yes yes no 1007 0 NFMHMO+AdvOTcf92ab37.I Type 1C WinAnsi yes yes no 1010 0 NFMHMP+AdvOTe34d3d11+fb Type 1C Custom yes yes yes 1020 0 NFMHNA+AdvPS3F4C13 Type 1C WinAnsi yes yes no 1005 0 NFMHNB+AdvOTa9103878 Type 1C WinAnsi yes yes no 1027 0 NFMHNC+AdvOTa9103878+fb Type 1C Custom yes yes yes 1033 0 NFMHOD+AdvOTa9103878+20 Type 1C WinAnsi yes yes no 1028 0 NFMIFF+AdvOT3b30f6db.B Type 1C WinAnsi yes yes no 653 0 NFMIGG+AdvOT56309c18.I Type 1C WinAnsi yes yes no 652 0 NFMIGH+AdvPS4721B4 Type 1C WinAnsi yes yes no 646 0 NFMKDN+AdvOT46dcae81+fb Type 1C Custom yes yes yes 658 0 NFMJPO+Arial-BoldMT CID TrueType Identity-H yes yes yes 664 0 NFMKFO+AdvP4C4E51 Type 1C WinAnsi yes yes no 665 0 NFMKFP+AdvOT46dcae81+20 Type 1C WinAnsi yes yes no 669 0 NFMNFN+Arial-BoldMT Type 1C WinAnsi yes yes no 697 0 NFMODJ+AdvOTd0125be5.BI Type 1C WinAnsi yes yes no 707 0 NFMOGJ+AdvOTb0c9bf5d+22 Type 1C Custom yes yes yes 725 0 NFMOGK+AdvP4C4E74 Type 1C Custom yes yes yes 718 0 NFMOGL+AdvOTa9103878+22 Type 1C Custom yes yes no 719 0 NFNADB+AdvOTf0bf83d5.I+20 Type 1C WinAnsi yes yes no 759 0 NFNADC+AdvOTf0bf83d5.I+fb Type 1C Custom yes yes yes 760 0 NFNADD+AdvOT455ab362 Type 1C WinAnsi yes yes no 746 0 NFNAEE+AdvOT3dc04c26.I Type 1C WinAnsi yes yes no 750 0 NFNAEF+AdvOT455ab362+20 Type 1C WinAnsi yes yes no 753 0 NFNAEG+AdvOT455ab362+fb Type 1C Custom yes yes yes 748 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-01-16 02:40:03 CET RepresentationInformation: JouBioChe_a2025m1v301_108061.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-01-08 13:16:44 CET Size: 1890641 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 1108 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: p38α and p38β regulate osmostress-induced apoptosis Destination: titlink1 Children: Item: Title: Results Destination: flink1 Children: Item: Title: Xenopus p38α and p38γ are phosphorylated in response to hyperosmotic shock Destination: slink1 Item: Title: Xenopus p38β is phosphorylated in response to hyperosmotic shock Destination: slink2 Item: Title: A constitutively active Xp38α or Xp38β accelerates osmostress-induced apoptosis Destination: slink3 Item: Title: Kinases and caspases are linked in a positive feedback loop: cytochrome c induces caspase-3 activation and phosphorylation ... Destination: slink4 Item: Title: Discussion Destination: flink2 Item: Title: Experimental procedures Destination: flink3 Children: Item: Title: Oocyte isolation and treatment Destination: slink5 Item: Title: RT-PCR and DNA constructs Destination: slink6 Item: Title: Site-directed mutagenesis and in vitro transcription Destination: slink7 Item: Title: Oocyte injection and hyperosmotic shock treatment Destination: slink8 Item: Title: Oocyte lysis and Western blot analysis Destination: slink9 Item: Title: Assay for DEVDase activity Destination: slink10 Item: Title: Statistical analysis Destination: slink11 Item: Title: Data availability Destination: flink4 Item: Title: Supporting information Destination: flink12 Item: Title: Author contributions Destination: flink5 Item: Title: Funding and additional information Destination: flink6 Item: Title: References Destination: blink1 Info: Title: p38α and p38β regulate osmostress-induced apoptosis Author: Nabil Ben Messaoud Subject: Journal of Biological Chemistry, 301 (2025) 108061. doi:10.1016/j.jbc.2024.108061 Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Sat Jan 04 13:46:52 CET 2025 ModDate: Sat Jan 04 13:48:52 CET 2025 ID: 0xc92b2846eadfb562b6bd6c712d0ae8c3, 0x7f7939b7ed7271428f2a8db3dc29471e Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 34 ImageHeight: 34 ColorSpace: palette color BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 225 ImageHeight: 50 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 103 ImageHeight: 98 ColorSpace: palette color BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 225 ImageHeight: 50 ColorSpace: black is zero BitsPerSample: 8 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López apoptosis p38 stress oocyte Xenopus cell death caspase osmotic shock Journal of Biological Chemistry, 301 (2025) 108061. doi:10.1016/j.jbc.2024.108061 The Authors journal Journal of Biological Chemistry © 2024 The Authors. 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Annotations: Annotation: Subtype: Link Rect: 53, 716, 290, 724 Annotation: Subtype: Link Rect: 53, 706, 290, 714 Annotation: Subtype: Link Rect: 53, 696, 112, 704 Annotation: Subtype: Link Rect: 53, 686, 290, 694 Annotation: Subtype: Link Rect: 53, 676, 176, 684 Annotation: Subtype: Link Rect: 53, 666, 290, 674 Annotation: Subtype: Link Rect: 53, 656, 211, 664 Annotation: Subtype: Link Rect: 53, 646, 290, 654 Annotation: Subtype: Link Rect: 53, 636, 290, 644 Annotation: Subtype: Link Rect: 53, 626, 290, 634 Annotation: Subtype: Link Rect: 53, 616, 133, 624 Annotation: Subtype: Link Rect: 53, 606, 290, 614 Annotation: Subtype: Link Rect: 53, 596, 290, 604 Annotation: Subtype: Link Rect: 53, 586, 290, 594 Annotation: Subtype: Link Rect: 53, 576, 134, 584 Annotation: Subtype: Link Rect: 53, 566, 290, 574 Annotation: Subtype: Link Rect: 53, 556, 290, 564 Annotation: Subtype: Link Rect: 53, 546, 290, 554 Annotation: Subtype: Link Rect: 53, 536, 274, 544 Annotation: Subtype: Link Rect: 53, 527, 290, 535 Annotation: Subtype: Link Rect: 53, 517, 290, 525 Annotation: Subtype: Link Rect: 53, 507, 118, 515 Annotation: Subtype: Link Rect: 53, 497, 290, 505 Annotation: Subtype: Link Rect: 53, 487, 290, 495 Annotation: Subtype: Link Rect: 53, 477, 208, 485 Annotation: Subtype: Link Rect: 53, 467, 290, 475 Annotation: Subtype: Link Rect: 53, 457, 290, 465 Annotation: Subtype: Link Rect: 53, 447, 89, 455 Annotation: Subtype: Link Rect: 53, 437, 290, 445 Annotation: Subtype: Link Rect: 53, 427, 290, 435 Annotation: Subtype: Link Rect: 53, 417, 89, 425 Annotation: Subtype: Link Rect: 53, 407, 290, 415 Annotation: Subtype: Link Rect: 53, 397, 290, 405 Annotation: Subtype: Link Rect: 53, 387, 81, 395 Annotation: Subtype: Link Rect: 53, 377, 290, 385 Annotation: Subtype: Link Rect: 53, 367, 290, 375 Annotation: Subtype: Link Rect: 53, 357, 290, 365 Annotation: Subtype: Link Rect: 53, 347, 218, 355 Annotation: Subtype: Link Rect: 53, 337, 290, 345 Annotation: Subtype: Link Rect: 53, 327, 290, 335 Annotation: Subtype: Link Rect: 53, 317, 290, 325 Annotation: Subtype: Link Rect: 53, 307, 97, 315 Annotation: Subtype: Link Rect: 53, 297, 290, 305 Annotation: Subtype: Link Rect: 53, 287, 290, 295 Annotation: Subtype: Link Rect: 53, 277, 290, 285 Annotation: Subtype: Link Rect: 53, 267, 137, 275 Annotation: Subtype: Link Rect: 53, 258, 290, 266 Annotation: Subtype: Link Rect: 53, 248, 290, 256 Annotation: Subtype: Link Rect: 53, 238, 256, 246 Annotation: Subtype: Link Rect: 53, 228, 290, 236 Annotation: Subtype: Link Rect: 53, 218, 290, 226 Annotation: Subtype: Link Rect: 53, 208, 220, 216 Annotation: Subtype: Link Rect: 53, 198, 290, 206 Annotation: Subtype: Link Rect: 53, 188, 290, 196 Annotation: Subtype: Link Rect: 53, 178, 290, 186 Annotation: Subtype: Link Rect: 53, 168, 205, 176 Annotation: Subtype: Link Rect: 53, 158, 290, 166 Annotation: Subtype: Link Rect: 53, 148, 290, 156 Annotation: Subtype: Link Rect: 53, 138, 260, 146 Annotation: Subtype: Link Rect: 53, 128, 290, 136 Annotation: Subtype: Link Rect: 53, 118, 290, 126 Annotation: Subtype: Link Rect: 53, 108, 290, 116 Annotation: Subtype: Link Rect: 53, 98, 102, 106 Annotation: Subtype: Link Rect: 53, 88, 290, 96 Annotation: Subtype: Link Rect: 53, 78, 290, 86 Annotation: Subtype: Link Rect: 53, 68, 132, 76 Annotation: Subtype: Link Rect: 316, 716, 553, 724 Annotation: Subtype: Link Rect: 316, 706, 553, 714 Annotation: Subtype: Link Rect: 316, 696, 518, 704 Annotation: Subtype: Link Rect: 316, 686, 553, 694 Annotation: Subtype: Link Rect: 316, 676, 394, 684 Annotation: Subtype: Link Rect: 316, 666, 553, 674 Annotation: Subtype: Link Rect: 316, 656, 553, 664 Annotation: Subtype: Link Rect: 316, 646, 553, 654 Annotation: Subtype: Link Rect: 316, 636, 392, 644 Annotation: Subtype: Link Rect: 316, 626, 553, 634 Annotation: Subtype: Link Rect: 316, 616, 553, 624 Annotation: Subtype: Link Rect: 316, 606, 522, 614 Annotation: Subtype: Link Rect: 316, 596, 553, 604 Annotation: Subtype: Link Rect: 316, 586, 553, 594 Annotation: Subtype: Link Rect: 316, 576, 553, 584 Annotation: Subtype: Link Rect: 316, 566, 448, 574 Annotation: Subtype: Link Rect: 316, 556, 553, 564 Annotation: Subtype: Link Rect: 316, 546, 553, 554 Annotation: Subtype: Link Rect: 316, 536, 451, 544 Annotation: Subtype: Link Rect: 316, 527, 553, 535 Annotation: Subtype: Link Rect: 316, 517, 553, 525 Annotation: Subtype: Link Rect: 316, 507, 553, 515 Annotation: Subtype: Link Rect: 316, 497, 390, 505 Annotation: Subtype: Link Rect: 316, 487, 553, 495 Annotation: Subtype: Link Rect: 316, 477, 553, 485 Annotation: Subtype: Link Rect: 316, 467, 519, 475 Annotation: Subtype: Link Rect: 316, 457, 553, 465 Annotation: Subtype: Link Rect: 316, 447, 553, 455 Annotation: Subtype: Link Rect: 316, 437, 424, 445 Annotation: Subtype: Link Rect: 316, 427, 553, 435 Annotation: Subtype: Link Rect: 316, 417, 396, 425 Annotation: Subtype: Link Rect: 316, 407, 553, 415 Annotation: Subtype: Link Rect: 316, 397, 553, 405 Annotation: Subtype: Link Rect: 316, 387, 553, 395 Annotation: Subtype: Link Rect: 316, 377, 449, 385 Annotation: Subtype: Link Rect: 316, 367, 553, 375 Annotation: Subtype: Link Rect: 316, 357, 553, 365 Annotation: Subtype: Link Rect: 316, 347, 352, 355 Annotation: Subtype: Link Rect: 316, 337, 553, 345 Annotation: Subtype: Link Rect: 316, 327, 553, 335 Annotation: Subtype: Link Rect: 316, 317, 553, 325 Annotation: Subtype: Link Rect: 316, 307, 344, 315 Annotation: Subtype: Link Rect: 316, 297, 553, 305 Annotation: Subtype: Link Rect: 316, 287, 553, 295 Annotation: Subtype: Link Rect: 316, 277, 553, 285 Annotation: Subtype: Link Rect: 316, 267, 420, 275 Annotation: Subtype: Link Rect: 316, 258, 553, 266 Annotation: Subtype: Link Rect: 316, 248, 553, 256 Annotation: Subtype: Link Rect: 316, 238, 344, 246 Annotation: Subtype: Link Rect: 316, 228, 553, 236 Annotation: Subtype: Link Rect: 316, 218, 553, 226 Annotation: Subtype: Link Rect: 316, 208, 522, 216 Annotation: Subtype: Link Rect: 316, 198, 553, 206 Annotation: Subtype: Link Rect: 316, 188, 553, 196 Annotation: Subtype: Link Rect: 316, 178, 553, 186 Annotation: Subtype: Link Rect: 316, 168, 506, 176 Annotation: Subtype: Link Rect: 316, 158, 553, 166 Annotation: Subtype: Link Rect: 316, 148, 553, 156 Annotation: Subtype: Link Rect: 316, 138, 553, 146 Annotation: Subtype: Link Rect: 316, 128, 392, 136 Annotation: Subtype: Link Rect: 316, 118, 553, 126 Annotation: Subtype: Link Rect: 316, 108, 553, 116 Annotation: Subtype: Link Rect: 316, 98, 361, 106 Annotation: Subtype: Link Rect: 316, 88, 553, 96 Annotation: Subtype: Link Rect: 316, 78, 553, 86 Annotation: Subtype: Link Rect: 316, 68, 408, 76 Checksum: 8d22faf6 Type: CRC32 Checksum: 097cd0ddf61872bd10db53ad94fa6170 Type: MD5 Checksum: db174a129a641648eee0c20e2262996083ac7908 Type: SHA-1 Checksum: 2d4a97f2600c3ca270e7013c2152f586bd7a4c384acdfdea07737a12700631b8 Type: SHA-256